Эффективность кормовой добавки с высокой степенью защищенности протеина в кормлении новотельных коров

Intensive dairy farming in modern conditions is impossible without a solid forage base and the use of high-quality forage resources. A high level of cow productivity presupposes adequate nutrition for the animal at all physiological periods of its life. Due to the fact that cows consume relatively little feed during the first period of lactation, the primary task of livestock breeders is to provide the body of highly productive animals with the necessary amount of energy, protein and other nutrients. The article presents the data of a scientific experiment on the use of non-degradable protein in the rumen PassPro Balance in diets for fresh cows. The feed additive under study contributes to an increase in the level of dry matter consumption by animals. The average daily milk yield of the experimental group, which received the studied supplement, significantly increased by 12.0% (P <0.05) in comparison with the control group. There was also established a tendency to an increase in the fat content in the milk of cows from the experimental group. According to the biochemical analysis of the blood serum of cows, the level of albumin in all animals was within the physiological norm. The content of globulins was below the norm in animals of all groups without significantly significant differences. The activity of the AST and ALT enzymes between the groups did not differ significantly. However, it should be noted that in both groups these indicators were within the normal range. The level of alkaline phosphatase tended to increase in the experimental group by 20.8% in comparison with the control group. Feeding PassPro Supplements Balance in the diets for the experimental group made it possible to receive 2565,00 rubles of additional profit, while the level of profitability of milk production increased by 2.02% relative to control.Ведение интенсивного молочного скотоводства в современных условиях невозможно без прочной кормовой базы и использования высококачественных кормовых средств. Высокий уровень продуктивности коров предполагает полноценное питание животного во все физиологические периоды его жизни. Ввиду того, что коровы в первый период лактации потребляют относительно мало корма, первостепенной задачей животноводов является обеспечение организма высокопродуктивных животных необходимым количеством энергии, протеина и других питательных веществ. В статье приведены данные научного эксперимента по использованию в рационах для новотельных коров не распадаемого в рубце протеина PassPro Баланс. Изучаемая кормовая добавка способствует повышению уровня потребления сухого вещества животными. Среднесуточный удой опытной группы, получавшей изучаемую добавку, достоверно увеличился – на 12,0% (P<0,05) в сравнении с контролем. Установлена также тенденция к повышению содержания жира в молоке коров опытной группы. Согласно данным биохимического анализа сыворотки крови коров, уровень содержания альбуминов у всех животных находился в пределах физиологической нормы. Содержание глобулинов было ниже нормы у животных всех групп без достоверно значимых различий. Активность ферментов AST и ALT между группами отличалась недостоверно. Однако следует отметить, что в обеих группах эти показатели были в пределах нормы. Уровень щелочной фосфатазы имел тенденцию к повышению в опытной группе на 20,8 % по сравнению с контролем. Скармливание добавки PassPro Баланс в рационах для опытной группы позволило получить 2565,00 руб. дополнительной прибыли, при этом уровень рентабельности производства молока повысился на 2,02% относительно контроля

Effectiveness of a feed additive with a high degree of protein protection in feeding fresh cows

Intensive dairy farming in modern conditions is impossible without a solid forage base and the use of high-quality forage resources. A high level of cow productivity presupposes adequate nutrition for the animal at all physiological periods of its life. Due to the fact that cows consume relatively little feed during the first period of lactation, the primary task of livestock breeders is to provide the body of highly productive animals with the necessary amount of energy, protein and other nutrients. The article presents the data of a scientific experiment on the use of non-degradable protein in the rumen PassPro Balance in diets for fresh cows. The feed additive under study contributes to an increase in the level of dry matter consumption by animals. The average daily milk yield of the experimental group, which received the studied supplement, significantly increased by 12.0% (P &lt;0.05) in comparison with the control group. There was also established a tendency to an increase in the fat content in the milk of cows from the experimental group. According to the biochemical analysis of the blood serum of cows, the level of albumin in all animals was within the physiological norm. The content of globulins was below the norm in animals of all groups without significantly significant differences. The activity of the AST and ALT enzymes between the groups did not differ significantly. However, it should be noted that in both groups these indicators were within the normal range. The level of alkaline phosphatase tended to increase in the experimental group by 20.8% in comparison with the control group. Feeding PassPro Supplements Balance in the diets for the experimental group made it possible to receive 2565,00 rubles of additional profit, while the level of profitability of milk production increased by 2.02% relative to control.</jats:p

Use of failure-to-rescue to identify international variation in postoperative care in low-, middle- and high-income countries: A 7-day cohort study of elective surgery

The incidence and impact of postoperative complications are poorly described. Failure-to-rescue, the rate of death following complications, is an important quality measure for perioperative care but has not been investigated across multiple health care systems. Methods. We analysed data collected during the International Surgical Outcomes Study, an international 7-day cohort study of adults undergoing elective inpatient surgery. Hospitals were ranked by quintiles according to surgical procedural volume (Q1 lowest to Q5 highest). For each quintile we assessed in-hospital complications rates, mortality, and failure-to-rescue. We repeated this analysis ranking hospitals by risk-adjusted complication rates (Q1 lowest to Q5 highest). Results. A total of 44 814 patients from 474 hospitals in 27 low-, middle-, and high-income countries were available for analysis. Of these, 7508 (17%) developed one or more postoperative complication, with 207 deaths in hospital (0.5%), giving an overall failure-to-rescue rate of 2.8%. When hospitals were ranked in quintiles by procedural volume, we identified a threefold variation in mortality (Q1: 0.6% vs Q5: 0.2%) and a two-fold variation in failure-to-rescue (Q1: 3.6% vs Q5: 1.7%). Ranking hospitals in quintiles by risk-adjusted complication rate further confirmed the presence of important variations in failureto- rescue, indicating differences between hospitals in the risk of death among patients after they develop complications. Conclusions. Comparison of failure-to-rescue rates across health care systems suggests the presence of preventable postoperative deaths. Using such metrics, developing nations could benefit from a data-driven approach to quality improvement, which has proved effective in high-income countries

Kuluttajabarometri maakunnittain 2000, 2. neljännes

Suomen virallinen tilasto (SVT

Use of failure-to-rescue to identify international variation in postoperative care in low-, middle- and high-income countries: a 7-day cohort study of elective surgery

This was an investigator-initiated study funded by Nestle Health Sciences through an unrestricted research grant and by a National Institute for Health Research (UK) Professorship held by R.P. The study was sponsored by Queen Mary University of London

Global patient outcomes after elective surgery: prospective cohort study in 27 low-, middle- and high-income countries The International Surgical Outcomes Study group

BACKGROUND: As global initiatives increase patient access to surgical treatments, there remains a need to understand the adverse effects of surgery and define appropriate levels of perioperative care. METHODS: We designed a prospective international 7-day cohort study of outcomes following elective adult inpatient surgery in 27 countries. The primary outcome was in-hospital complications. Secondary outcomes were death following a complication (failure to rescue) and death in hospital. Process measures were admission to critical care immediately after surgery or to treat a complication and duration of hospital stay. A single definition of critical care was used for all countries. RESULTS: A total of 474 hospitals in 19 high-, 7 middle- and 1 low-income country were included in the primary analysis. Data included 44 814 patients with a median hospital stay of 4 (range 2-7) days. A total of 7508 patients (16.8%) developed one or more postoperative complication and 207 died (0.5%). The overall mortality among patients who developed complications was 2.8%. Mortality following complications ranged from 2.4% for pulmonary embolism to 43.9% for cardiac arrest. A total of 4360 (9.7%) patients were admitted to a critical care unit as routine immediately after surgery, of whom 2198 (50.4%) developed a complication, with 105 (2.4%) deaths. A total of 1233 patients (16.4%) were admitted to a critical care unit to treat complications, with 119 (9.7%) deaths. Despite lower baseline risk, outcomes were similar in low- and middle-income compared with high-income countries. CONCLUSIONS: Poor patient outcomes are common after inpatient surgery. Global initiatives to increase access to surgical treatments should also address the need for safe perioperative care. STUDY REGISTRATION: ISRCTN5181700

The surgical safety checklist and patient outcomes after surgery: a prospective observational cohort study, systematic review and meta-analysis

© 2017 British Journal of Anaesthesia Background: The surgical safety checklist is widely used to improve the quality of perioperative care. However, clinicians continue to debate the clinical effectiveness of this tool. Methods: Prospective analysis of data from the International Surgical Outcomes Study (ISOS), an international observational study of elective in-patient surgery, accompanied by a systematic review and meta-analysis of published literature. The exposure was surgical safety checklist use. The primary outcome was in-hospital mortality and the secondary outcome was postoperative complications. In the ISOS cohort, a multivariable multi-level generalized linear model was used to test associations. To further contextualise these findings, we included the results from the ISOS cohort in a meta-analysis. Results are reported as odds ratios (OR) with 95% confidence intervals. Results: We included 44 814 patients from 497 hospitals in 27 countries in the ISOS analysis. There were 40 245 (89.8%) patients exposed to the checklist, whilst 7508 (16.8%) sustained ≥1 postoperative complications and 207 (0.5%) died before hospital discharge. Checklist exposure was associated with reduced mortality [odds ratio (OR) 0.49 (0.32–0.77); P\u3c0.01], but no difference in complication rates [OR 1.02 (0.88–1.19); P=0.75]. In a systematic review, we screened 3732 records and identified 11 eligible studies of 453 292 patients including the ISOS cohort. Checklist exposure was associated with both reduced postoperative mortality [OR 0.75 (0.62–0.92); P\u3c0.01; I2=87%] and reduced complication rates [OR 0.73 (0.61–0.88); P\u3c0.01; I2=89%). Conclusions: Patients exposed to a surgical safety checklist experience better postoperative outcomes, but this could simply reflect wider quality of care in hospitals where checklist use is routine