Electro-oxidation of amoxicillin using titanium electrodes electrophoretically coated by iridium or ruthenium with tantalum oxides

© 2020 Society of Chemical Industry (SCI) BACKGROUND: Amoxicillin (AMX) is one of the pharmaceutical compounds in waters being targeted in wastewater decontamination studies, and some of the technological alternatives to degrade it involve using modified surfaces with transition metal oxides, such as IrO2/Ta2O5|Ti and RuO2/Ta2O5|Ti, for in situ production of hydroxyl radical (•OH) to oxidize AMX in aqueous media. RESULTS: The IrO2/Ta2O5|Ti 70:30 electrode was best suited for AMX electro-oxidation, with 99.23% removal measured by HPLC-UV–Vis, 81.13% by COD removal, and current efficiency of 41.1% in 0.1 mol L–1 Na2SO4 after applying 15 mA for 6 h. These results are due to a larger surface area (251.67 cm2) and a higher amount of •OH radicals being generated by cm2 in neutral pH (3.8 mol L–1 cm−2) compared to the other electrodes. CONCLUSION: This paper shows the simulation of the experimental data regarding the complete degradation of AMX (100%) by HPLC, comparing the experimental results and simulation results for AMX degradation using the IrO2/Ta2O5|Ti 70:30. The modeling predicts and validates the disengagement of COD obtained experimentally, considering the mechanism proposed by Trovó and collaborators for the electro-oxidation of AMX to product C6 (C16H22N3O7S) by generating •OH. © 2020 Society of Chemical Industry (SCI)

Serbian Language version of the Modified Checklist for Autism in Toddlers, Revised, with Follow-Up: Cross-Cultural Adaptation and Assessment of Reliability

Early detection of Autism Spectrum Disorder (ASD) has proven to be of high significance, however there is a limited availability of ASD screening tools in Serbian language. In this study we aim to translate, assess reliability and, in part, test the applicability of Modified Checklist for Autism in Toddlers, Revised, with Follow-Up (M-CHAT R/F) in Serbian Healthcare environment. We screened 128 children in three primary healthcare centres and 20 children in a tertiary psychiatric center, using M-CHAT R/F translated into Serbian language, between December 2014 and October 2015. At the end of the screening process 80% of participants in the risk group screened positive for ASD, while in the control group 4 (3.1%) participants screened positive, with a mean total scores of 8.25 and 0.66 respectively. The Cronbach's a coefficient was 0.91 and Guttman's.6 was 0.93. Test-retest reliability was deemed as acceptable, and no significant correlation was found between M-CHAT-R/F scores and Epworth Sleepiness Scale for children scores. The Serbian version of the M-CHAT-R/F has shown satisfactory reliability. We can therefore assert that it is a reliable tool for identifying ASD and it can be used in clinical practice to improve early detection, assessment and treatment

Crecimiento y actividad de las enzimas digestivas de la trucha arcoíris (Oncorhynchus mykiss) alimentadas con probióticos autóctonos

Background. Probiotics in aquaculture are becoming important to improve the growth of fish, because of some useful modifications of physiological process, and consequently in fish growth.Goals.To assess the effects of two autochthonous bacterial strains, with probiotics features, on rainbow trout growth and digestive enzyme activities. Methods. In this study, was tested the effect of Bacillus pumilus (BP), Bacillus sp. (BSP) and the mixture (BPSP), on the growth and the activity of digestive enzymes of rainbow trout. The autochthonous strains, previously characterized as potentials probiotics in vitro, were administered individually at 1 x 107CFU g-1food, and as a mixture, the cellular concentration 0.5 x 107CFU g-1 food each one; during eight weeks. Results. Neither of the strains used generated significative growth, compared to the control. Were the fish fed with BSP that had the best growth, respect to BP and BPSP. The highest activity of enzymes was obtained in the fish treated with bacteria, and only in the case of BPSP the fish had a significant increase (P < 0.05) of proteases and amylase activity, compared with CTRL. Under the current trial conditions, strains BP and BSP, had no positive effects on growth and enzyme activities. The mixture improved the activity of protease and amylase of rainbow trout.Antecedentes: Los probioticos en la acuicultura han ganado importancia, ya que pueden mejorar la salud de los peces debido a los efectos positivos en la fisiologia digestiva de los animales y, consecuentemente, en el crecimiento. Objetivos: Evaluar el efecto de dos cepas bacterianas autoctonas con potencial probiótico sobre el crecimiento y la actividad de las proteasas totales, lipasa y amilasa de la trucha arcoiris. Métodos: Se evaluo el efecto de Bacillus pumilus (BP), Bacillus sp. (BSP) y la mezcla (BPSP) en el crecimiento y la actividad de enzimas digestivas de la trucha arcoiris. Las cepas autoctonas, previamente caracterizadas como potenciales probioticos in vitro, fueron suministradas a los peces a una densidad celular de 1x107 UFC g-1de alimento, individualmente y la mezcla, a la mitad de la concentracion cada una; durante ocho semanas. Resultados: Ninguna de las cepas empleadas genero crecimiento significativo, comparado con el control. Sin embargo, los peces alimentados con BSP tuvieron mejor crecimiento, respecto de BP y BPSP. La actividad enzimatica (proteasas, lipasa y amilasa) mas alta se obtuvo en los peces alimentados con BPSP, y fueron estadísticamente diferentes (P< 0.05) del control. Conclusiones: Las condiciones de experimentacion evaluadas no generaron efecto significativo sobre el crecimiento y la actividad de las enzimas digestivas cuando las cepas se suministraron individualmente. El consorcio bacteriano incremento significativamente la actividad de los tres grupos enzimaticos de la trucha arcoiris

1er. Coloquio de educación para el diseño en la sociedad 5.0

Las memorias del 1er. Coloquio de Educación para el Diseño en la Sociedad 5.0 debenser entendidas como un esfuerzo colectivo de la comunidad de académicos de la División de Ciencias y Artes para el Diseño, que pone de manifiesto los retos y oportunidades que enfrenta la educación en diseño en un contexto de cambio acelerado y rompimiento de paradigmas.El evento se realizó el pasado mes de mayo de 2018 y se recibieron más de 50 ponencias por parte de las profesoras y profesores de la División.Las experiencias y/o propuestas innovadoras en cuanto a procesos de enseñanza y aprendizaje que presentan los autores en cada uno de sus textos son una invitación a reflexionar sobre nuestra situación actual en la materia, y emprender acciones en la División para continuar brindando una educación de calidad en diseño a nuestras alumnas, alumnos y la sociedad.Adicionalmente, se organizaron tres conferencias magistrales sobre la situación actual de la educación en Diseño y de las Instituciones de Educación Superior, impartidas por el Mtro. Luis Sarale, profesor de la Universidad Nacional de Cuyo en Mendoza (Argentina), y Presidente en su momento, de la Red de Carreras de Diseño en Universidades Públicas Latinoamericanas (DISUR), el Dr. Romualdo López Zárate, Rector de la Unidad Azcapotzalco, así como del Mtro. Luis Antonio Rivera Díaz, Jefe de Departamento de Teoría y Procesos del Diseño de la División de la Ciencias de la Comunicación y Diseño, en la Unidad Cuajimalpa de nuestra institución.La publicación de estas memorias son un esfuerzo divisional, organizado desde la Coordinación de Docencia Divisional y la Coordinación de Tecnologías del Aprendizaje, del Conocimiento y la Comunicación, para contribuir a los objetivos planteados en el documento ACCIONES:Agenda CyAD2021, en particular al eje de Innovación Educativa. Es necesario impulsar a todos los niveles de la División espacios de discusión orientados a reflexionar sobre el presente y futuro en la educación del diseñador, que contribuya a mejorar la calidad de la docencia y favorezca al fortalecimiento de los procesos de enseñanza y aprendizaje.Finalmente, extiendo un amplio reconocimiento a todos los miembros de la División que hicieron posible este evento, así como a todos los ponentes y participantes por compartir su conocimiento para que la División sea cada día mejor

Un determinante con contenido: El caso de su/sus

En el español de la Ciudad de México es frecuente que el proclítico su/sus aparezca modificando nominales de diferente naturaleza semántica. En el presente trabajo se muestra que esta forma, estrictamente funcional, funge dentro de la frase nominal como un determinante con contenido. La finalidad es mostrar que las formas su/sus tienen una serie de rasgos semánticos binarios (definitud/anáfora-catáfora, posesión/ relación, proximidad/empatía), los cuales se distribuyen en una escala jerárquica, de manera tal que se activan o se ponen en relieve a partir del condicionamiento contextual de la frase nominal. En esta propuesta, la posesión es entendida como una relación que se establece entre una entidad que aparece en el dominio del poseedor y una entidad que puede ser poseída o transferida. Los rasgos de su/sus se interpretan en frases nominales simples y complejas a partir de la revisión del Proyecto para el Estudio Sociolingüístico del Español de España y de América (PRESEEA) y de otro corpus integrado por registros orales de personas con escolaridad media y superior. Se muestra que, en frases del tipo su celular de Ramón, la forma su codifica definitud/ catáfora, mientras que la preposición de expresa la relación de posesión. Lo anterior deja al descubierto hallazgos relevantes para brindar una explicación detallada ante la polisemia de los proclíticos posesivos de tercera person

Multimodal therapy of idiopathic pyoderma gangrenosum

A 13-year old girl was admitted to the University of California Davis Medical Center for evaluation and treatment of cutaneous bullae and ulcerations over her lower extremities that were refractory to antibiotic therapy and incision and drainage.  Her disease continued to worsen with the appearance of multiple new bullae and the progression of old ones into deep ulcers with undermined borders.  Biopsy revealed a neutrophilic dermatosis and diagnostic work-up was negative for infectious or autoimmune etiologies.  Given her clinical presentation, biopsy results, and negative work-up, a diagnosis of pyoderma gangrenosum (PG) was made and she was started on immunosuppressive medications.  The patient was started on a multidrug regimen of prednisone and cyclosporine but remission was not achieved until the addition of adalimumab.  After the inflammatory component of her disease was under control, wound care measures were maximized to promote ulcer healing.  Wound care measures included compression and debridement.  Upon complete closure of all wounds she was successfully transitioned to mycophenolate mofetil monotherapy for maintenance therapy.  This case emphasizes the need for combinational therapy to successfully treat severe cases of PG, which are often refractory to monotherapy with prednisone or cyclosporine.   It also highlights the importance of appropriate wound care to achieve complete ulcer healing

Multimodal therapy of idiopathic pyoderma gangrenosum

A 13-year old girl was admitted to the University of California Davis Medical Center for evaluation and treatment of cutaneous bullae and ulcerations over her lower extremities that were refractory to antibiotic therapy and incision and drainage.  Her disease continued to worsen with the appearance of multiple new bullae and the progression of old ones into deep ulcers with undermined borders.  Biopsy revealed a neutrophilic dermatosis and diagnostic work-up was negative for infectious or autoimmune etiologies.  Given her clinical presentation, biopsy results, and negative work-up, a diagnosis of pyoderma gangrenosum (PG) was made and she was started on immunosuppressive medications.  The patient was started on a multidrug regimen of prednisone and cyclosporine but remission was not achieved until the addition of adalimumab.  After the inflammatory component of her disease was under control, wound care measures were maximized to promote ulcer healing.  Wound care measures included compression and debridement.  Upon complete closure of all wounds she was successfully transitioned to mycophenolate mofetil monotherapy for maintenance therapy.  This case emphasizes the need for combinational therapy to successfully treat severe cases of PG, which are often refractory to monotherapy with prednisone or cyclosporine.   It also highlights the importance of appropriate wound care to achieve complete ulcer healing

Degradation of phenols by heterogeneous electro-Fenton with a Fe3O4-chitosan composite and a boron-doped diamond anode

Four phenolic compounds, either as single molecules or in mixtures, were treated by heterogeneous electro-Fenton using an undivided cell with a Ti mesh cathode, put in contact with a composite made of Fe3O4 nanoparticles (NPs) on chitosan (CS) made by chemical reduction, and a boron-doped diamond (BDD) anode. The removals attained upon the application of 2.3 V for 4 h to model solutions with 0.5 mol dm-3 H2SO4 as electrolyte were: 93% for phenol, 30% for m-chlorophenol, 24% for o-chlorophenol and 22% for p-chlorophenol. COD removal efficiencies reached 95% for phenol and m-chlorophenol, 88% for p-chlorophenol and 57% for o-chlorophenol. The degradation was feasible thanks to the production of hydroxyl radicals, both on the BDD surface (i.e., BDD(¿OH)) from water oxidation and in the bulk from Fenton's reaction. The composite cathode allowed the continuous H2O2 electrogeneration and Fe(III) reduction to Fe(II). The reaction between H2O2 and Fe(II) in solid or liquid phase yielded ¿OH. The disappearance of phenols was much slower in the absence of the composite catalyst