CHRONIC INFLAMMATORY DEMYELINATING POLYNEUROPATHY

Chronic inflammatory demyelinating polyneuropathy (CIDP) merupakan penyakit neuropati autoimun kronik. CIDP klasik ditandai dengan hilangnya persepsi sensorik dan kelemahan anggota gerak secara progresif dan disertai hilangnya refleks selama lebih dari 8 minggu. Penyakit ini cukup jarang terjadi, namun apabila tidak di tatalaksana dengan tepat dapat menyebabkan kecacatan. Diagnosis CIDP ditegakkan berdasarkan gejala klinis, pemeriksaan analisa LCS, dan pemeriksaan  elektrodiagnostik. Pilihan terapi CIDP yang cukup efektif dan terjangkau adalah kortikosteroid, dimana obat ini berfungsi menekan inflamasi dengan menghambat aktivitas  sel T. Prognosis CIDP relatif baik pada pasien usia muda, gejala kelemahan otot proksimal, respon terhadap terapi steroid, dan dari studi elektrofisiologi terdapat perlambatan conduction velocities yang ringa

KADAR BETA AMYLOID 42 PLASMA PADA PENYAKIT PARKINSON DAN HUBUNGANNYA DENGAN SUBTIPE MOTORIK

Latar Belakang: Penyakit Parkinson (PD) adalah penyakit neurodegeneratif kronik progresif yang secara klinis diklasifikasikan menjadi subtipe tremor dan postural instability and gait difficulty (PIGD). Subtipe PIGD memiliki gejala motorik lebih berat dibandingkan tremor. Biomarker Beta Amyloid 42 (Aβ-42) diduga berperan dalam progresivitas penyakit PD melalui interaksinya dengan protein Alfa Sinuklein. Tujuan penelitian ini untuk mengetahui kadar Aβ-42 plasma penyakit Parkinson dan hubungannya dengan subtipe motorik. Metode: Penelitian ini menggunakan desain cross sectional. Sampel dipilih dengan metode consecutive sampling. Semua subjek diperiksa kadar Aβ-42 plasma. Subtipe motorik PD diklasifikasikan berdasarkan rasio skor motorik MDS-UPDRS. Analisa statistik menggunakan SPSS dengan nilai p <0.05 dianggap bermakna secara statistik. Hasil: Penelitian ini terdiri dari 50 orang penderita Parkinson dan 20 orang kontrol. Pada kelompok PD, didapatkan rerata usia penderita 63,30±8,1 tahun dan median kadar Aβ-42 plasma 29,01 ng/L. Dari 50 penderita, 44 % berada pada stadium Hoehn and Yahr II dan 56% memiliki subtipe tremor. Setelah dianalisis, tidak terdapat perbedaan bermakna kadar Aβ-42 plasma penderita PD dan kontrol (p=0,28). Terdapat kecenderungan peningkatan kadar Aβ-42 plasma pada subtipe PIGD. Namun setelah dianalisis tidak ditemukan hubungan kadar Aβ-42 plasma dengan subtipe motorik (p= 0,07). Kesimpulan: Pada penelitian ini median kadar Aβ-42 plasma penderita PD 29,01 ng/L. Tidak terdapat perbedaan kadar Aβ-42 plasma penderita PD dan kontrol. Kadar Aβ-42 plasma cenderung lebih tinggi pada subtipe PIGD, namun tidak ditemukan hubungan kadar Aβ-42 plasma dengan subtipe motorik

KORELASI AMBANG NYERI TEKAN OTOT DENGAN DERAJAT NYERI DAN DISABILITAS PADA PENGENDARA OJEK ONLINE YANG MENDERITA NYERI PUNGGUNG BAWAH MIOFASIAL

Background: Online taxi rider is one of the jobs that requires the rider to be in a sitting or flexed position for a long time. An ergonomic position at work affects the pressure and tension of the lower back muscles. Continuous muscle pressure and strain has the risk of causing myofascial low back pain (LBP) in Online taxi riders. Objectives: This study aims to determine the correlation between the pressure threshold and the degree of pain and degree of disability in online motorcycle taxi drivers who suffer from LBP. Methods: This study is an observational study with a cross-sectional design. All samples were examined for muscle pressure at trigger points at paraspinal mucle in the lower back area using an Algometer. Assessment of the degree of pain was carried out using the Numeric Pain Scale instrument and the degree of disability was assessed by the Oswetri Disability Index. Results: In this study, 30 online Online taxi riders were found with complaints of myofascial low back pain with an average pressure threshold that causes pain at the trigger point of 5.03 ± 1.3 kgf. After conducting bivariate analysis with the Pearson test, no significant correlation was found between the threshold of muscle tension and the degree of pain and degree of disability of Online taxi riders who suffer from LBP (p&gt;0.05). Conclusion: There is no correlation between the threshold of muscle pressure and the degree of pain and disability of Online taxi rider. Keywords: threshold of tenderness, myofacial lower back pain, online taxi rider

HUBUNGAN HASIL PEMERIKSAAN NEUTROPHIL TO LYMPHOCYTE RATIO (NLR) DENGAN DERAJAT KEPARAHAN COVID-19 DI RSUD H. ABDUL MANAP JAMBI TAHUN 2021

ABSTRACT Background: Coronavirus disease (COVID-19) was initially found in Wuhan, Hubei Province, China, in December 2019. Simple hematology laboratory tests such as Neutrophil to Lymphocyte Ratio (NLR) measurements are used to describe the prognosis of patients in various clinical circumstances. This study aims to describe the correlation between NLR test results with the severity degree of COVID-19 patients without pregnancy and comorbid in RSUD H. Abdul Manap Jambi from January to December 2021. Methods: The research used a retrospective cross-sectional method. NLR data were collected from medical records and laboratory tests of COVID-19 patients. The Spearman test was used for bivariate analysis. Results: There were 38 samples in this study, with the majority of the patient with NLR &lt;3,13 (58%) and patients with mild and moderate COVID-19 severity (39,5%). Based on the statistical test between NLR and COVID-19, the severity degree gets p-value= = 0,001 with r-correlation= = 0,829. Conclusion: It can be concluded that there is a strong correlation between Neutrophil to Lymphocyte Ratio (NLR) with Covid-19 severity degree patients without pregnancy and comorbid in RSUD H. Abdul Manap Jambi from January to December 2021. Keywords: COVID-19, NLR, Severity Degree, Characteristic &nbsp; ABSTRAK Latar Belakang: Coronavirus disease (COVID-19) pertama kali ditemukan di Wuhan, provinsi Hubei, China pada Desember 2019. Pemeriksaan laboratorium Hematologi sederhana seperti pengukuran Neutrophil to Lymphocyte Ratio (NLR) dapat digunakan sebagai faktor untuk menentukan prognosis pasien COVID-19 dalam berbagai kondisi klinis. Penelitian ini bertujuan untuk mengetahui hubungan hasil pemeriksaan Neutrophil to Lymphocyte Ratio (NLR) dengan derajat keparahan pasien COVID-19 tanpa kehamilan dan komorbid di RSUD H. Abdul Manap Jambi pada bulan Januari hingga Desember tahun 2021. Metode: Penelitian ini menggunakan metode retrospective cross sectional dengan melihat data rekam medis dan pemeriksaan laboratorium pasien COVID-19. Analisis bivariat menggunakan uji Spearman. Hasil: Dari 38 sampel penelitian, persentase terbanyak sampel adalah pasien dengan hasil perhitungan NLR &lt;3,13 (58%) dan pasien dengan derajat keparahan COVID-19 ringan dan sedang (39,5%). Berdasarkan uji statistik diperoleh p-value &lt;0,001 dan r-korelasi adalah 0,829. Kesimpulan: Terdapat hubungan sangat kuat antara hasil pemeriksaan Neutrophil to Lymphocyte Ratio (NLR) dengan derajat keparahan pasien COVID-19 tanpa kehamilan dan komorbid di RSUD H. Abdul Manap Jambi pada bulan Januari hingga Desember tahun 2021. Kata Kunci : COVID-19, NLR, Derajat Keparahan, Karakteristik &nbsp

Sikap Mahasiswa Program Studi Pendidikan Dokter Angkatan 2013 Fakultas Kedokteran dan Ilmu Kesehatan Universitas Jambi terhadap Pelajaran Matematika dan Sains

ABSTRACT Background : Attitude that’s performed by someone can predict behaviors of the future. It shows what person will do in coming activities. Human’s attitude towards certain subject represents an important predictor that brings to academic achievement. Students who mayor in the medical faculty are the ones who naturally are interested in the subjects of mathematics and Natural science in their school. These subjects represent the main lessons that the medical students learn, even those subjects become parts of tested component selection in the entrance examination of new students. Positive attitude owned by students who have a great interest in those subjects make someone pleased in learning activities, and will cause good learning achievment. In fact, what are learnt in their interests of  mathematics and science represent a condition of the lecture activities in the medical faculty. The purpose of this research is to show descriptions of Medical Students’ attitudes towards Mathematics and Science subjects. It consists of general and component descriptions about Mathematics, Physics, Chemistry and Biology. Methods : This is a descriptive research. Subjects of the researh are taken from population of the Medical Students of Jambi University the year 2013. The population of the research consists of 142 students, 45 males and 97 females. The research instrument uses attitude scale towards Mathematics and  Natural Science. It has face, logic and construct validity. It has 0,92 parallel test reliability that consists of 12 items. Result : Medical students have positive attitudes towards Biology. They have neutral attitude towards Mathematics, Physics and Chemistry. There are greater positive attitude towards Biology. Very small numbers of students have negative attitude towards this subject. On Mathematics, there are more students who have positive attitude rather than negative ones. On Physics, there are twice numbers of students who have negative attitudes than positive ones. On chemistry, there are many students have positive attitudes. Conclusion: Medical students feel that learning Biology is  easy and simple subject. They evaluate it positively. They think that Biology is an important and useful subject. They are always ready waiting for learning this subject in class. They feel very comfortable with this subject.   Keywords: Attitude, Scale, Validity, Academic Achievement, Mathematics Scienc

PENYULUHAN KESEHATAN MENJAGA ANAK SEHAT DAN BAHAGIA DI MASA PANDEMI COVID-19

ABSTRACT The COVID-19 pandemic has had an impact on learning methods, namely from face-to-face to distance learning. Digital devices can provide highly sophisticated learning opportunities for early childhood. However, in conditions of activity restrictions during the pandemic, people have a tendency to use digital devices as a means of education, entertainment, and social interaction, which means that they also increase the duration of screen time in their daily lives. According to the American Academy of Child and Adolescent Psychiatry (AACAP), the maximum screen time for toddlers is 1 hour per day. Excessive screen time in children has been shown to be associated with behavioral health problems. The level of parental knowledge regarding the allowed screen time duration is quite good. This can be seen from the survey results where, after giving the material, respondents who have children in the 3-5 year age group who know the screen time duration is less than 1 hour are around 84.7% of respondents, where before receiving the material only 63.4% of respondents . Meanwhile, for respondents who have children aged 6-12 years as much as 77.1% know screen time after getting the material, where previously only 63.9%. It can be concluded that the implementation of this counseling was able to increase the knowledge of parents about the impact of excessive use of gadgets so as to prevent the adverse effects of gadgets such as negative behavior, obesity, and internet or gadget addiction. In addition, it is necessary to conduct counseling on the adverse effects of using gadgets in the adolescent and adult age groups. Keywords: COVID-19, Child Health, Screen Time &nbsp; ABSTRAK Pandemi COVID-19 memiliki dampak pada metode pembelajaran yaitu dari tatap muka menjadi pembelajaran jarak jauh. Perangkat&nbsp; digital&nbsp; dapat memberikan&nbsp; peluang&nbsp; belajar&nbsp; yang&nbsp; sangat&nbsp; canggih&nbsp; bagi&nbsp; anak&nbsp; usia&nbsp; dini.&nbsp; Namun dalam kondisi pembatasan aktivitas selama pandemi, masyarakat memiliki kecenderungan untuk menggunakan perangkat digital sebagai sarana pendidikan, hiburan, dan interaksi sosial, yang artinya turut meningkatkan durasi screen time dalam keseharian. Menurut American Academy of Child and Adolescent Psychiatry (AACAP), durasi screen time pada balita maksimal 1 jam per hari. Durasi screen time yang berlebihan pada anak-anak telah diketahui memiliki asosiasi terhadap permasalahan perilaku kesehatan. Tingkat pengetahuan orang tua mengenai durasi screen time yang diperbolehkan sudah cukup baik. Ini terlihat dari hasil survey dimana, setelah pemberian materi, pada responden yang memiliki anak di kelompok usia 3-5 tahun yang mengetahui durasi screen time kurang dari 1 jam adalah sekitar 84,7% responden, dimana sebelum mendapat materi hanya 63,4% responden. Sedangkan untuk responden yang memiliki anak usia 6-12 tahun sebanyak 77,1% mengetahui screen time setelah mendapatkan materi, dimana sebelumnya hanya 63,9%. Dapat disimpulkan pelaksanaan penyuluhan ini ternyata dapat meningkatkan pengetahuan para orang tua mengenai dampak penggunaan gadget berlebihan sehingga mencegah terjadinya efek buruk gadget seperti perilaku negatif, obesitas, dan kecanduan internet atau gadget. Selain itu perlu dilakukan penyuluhan dampak buruk penggunaan gadget pada kelompok usia remaja dan dewasa. Kata Kunci: COVID-19, Kesehatan Anak, Screen Tim

Sikap Mahasiswa Program Studi Pendidikan Dokter Angkatan 2013 Fakultas Kedokteran Dan Ilmu Kesehatan Universitas Jambi Terhadap Pelajaran Matematika Dan Sains

Background : Attitude that's performed by someone can predict behaviors of the future. It shows what person will do in coming activities. Human's attitude towards certain subject represents an important predictor that brings to academic achievement. Students who mayor in the medical faculty are the ones who naturally are interested in the subjects of mathematics and Natural science in their school. These subjects represent the main lessons that the medical students learn, even those subjects become parts of tested component selection in the entrance examination of new students. Positive attitude owned by students who have a great interest in those subjects make someone pleased in learning activities, and will cause good learning achievment. In fact, what are learnt in their interests of mathematics and science represent a condition of the lecture activities in the medical faculty. The purpose of this research is to show descriptions of Medical Students' attitudes towards Mathematics and Science subjects. It consists of general and component descriptions about Mathematics, Physics, Chemistry and Biology. Methods : This is a descriptive research. Subjects of the researh are taken from population of the Medical Students of Jambi University the year 2013. The population of the research consists of 142 students, 45 males and 97 females. The research instrument uses attitude scale towards Mathematics and Natural Science. It has face, logic and construct validity. It has 0,92 parallel test reliability that consists of 12 items. Result : Medical students have positive attitudes towards Biology. They have neutral attitude towards Mathematics, Physics and Chemistry. There are greater positive attitude towards Biology. Very small numbers of students have negative attitude towards this subject. On Mathematics, there are more students who have positive attitude rather than negative ones. On Physics, there are twice numbers of students who have negative attitudes than positive ones. On chemistry, there are many students have positive attitudes. Conclusion: Medical students feel that learning Biology is easy and simple subject. They evaluate it positively. They think that Biology is an important and useful subject. They are always ready waiting for learning this subject in class. They feel very comfortable with this subject

Pemeriksaan Status Gizi dan Edukasi Nutrisi Pada Pasien Hipertensi

Prevalensi hipertensi di Indonesia terus mengalami peningkatan dari tahun ke tahun. Hampir sebagian besar (50%)&nbsp; pasien hipertensi memiliki faktor risiko kardiovaskuler , yaitu diabetes, dislipidemia, overweight dan obesitas, hiperurisemia dan sindroma metabolik. Salah satu upaya yang dapat dilakukan untuk mengurangi resiko terjadinya komplikasi kardiovaskuler pada penyakit hipertensi&nbsp; adalah dengan melakukan pemantauan status gizi dan pengaturan pola makan pada pasien hipertensi. Pada pasien hipertensi pengaturan pola makan bertujuan untuk menstabilkan tekanan darah, mencegah komplikasi organ-organ vital, mencegah penyakit stroke dan PJK, mencegah kematian dan meningkatkan kualitas hidup pasien hipertens

HUBUNGAN SCREEN TIME DENGAN KEJADIAN MIGRAIN PADA MAHASISWA KEDOKTERAN UNIVERSITAS JAMBI ANGKATAN 2018

ABSTRACT Background: Migraine is one of the most common primary headache complaints. Migraine can occur due to trigger factors including foods with certain ingredients (such as tyramine, chocolate), menstrual cycles, weather, sleep patterns, bright light, and screen time. Screen time is the total time spent viewing or watching gadget screens such as televisions, computers (laptops), smartphones, tablets and video games. Objectives: To determine the relationship between screen time and the incidence of migraine in medical students at Jambi University. Methods: This research is a quantitative analytic study with a cross sectional design. Respondents consisted of 93 medical students at Jambi University Batch 2018 who were taken by the total sampling method and had met the inclusion and exclusion criteria. Screen time data and migraine incidence were assessed using a questionnaire. Analysis of the relationship between the two variables was tested by chi-square test and processed with SPSS version 25. Results: The results showed that there was a significant relationship between screen time and the incidence of migraine. Conclusions: the longer the use of screen time, the higher the incidence of migraine in medical students at Jambi University batch 2018. Keywords: Migraine, Screen time &nbsp; ABSTRAK Latar belakang: Migrain merupakan salah satu keluhan nyeri kepala primer yang paling sering ditemukan. Kejadian migrain dapat terjadi karena adanya faktor pemicu diantaranya makanan dengan kandungan tertentu (seperti tiramin, cokelat), siklus menstruasi, cuaca, pola tidur, cahaya yang terang, dan screen time. Screen time adalah waktu total yang dihabiskan untuk melihat atau menonton layar gadget seperti televisi, komputer (laptop), smartphone, tablet dan video game. Tujuan: Mengetahui hubungan antara screen time dengan kejadian migrain pada mahasiswa kedokteran Universitas Jambi. Metode: Penelitian ini merupakan penelitian analitik kuantitatif dengan desain cross sectional. Responden terdiri dari 93 mahasiswa kedokteran Universitas Jambi Angkatan 2018 yang diambil dengan metode total sampling dan telah memenuhi kriteria inklusi dan eksklusi. Data screen time dan kejadian migrain dinilai dengan kuisioner. Analisis hubungan antara dua variabel diuji dengan uji chi-square dan diolah dengan SPSS versi 25. Hasil: Hasil penelitian didapatkan adanya hubungan antara screen time dengan kejadian migrain. Kesimpulan: Semakin lama penggunaan screen time maka akan meningkatkan kejadian migrain pada mahasiswa kedokteran Universitas Jambi angkatan 2018. Kata kunci: Migrain, Screen tim

Hypovitaminosis D In Chronic Low Back Pain

Background: Vitamin D deficiency has been linked to various pain conditions, including chronic low back pain. The role of vitamin D for the health of the musculoskeletal system involves the downregulation of pro-inflammatory cytokines that contribute to pain and the upregulation of anti-inflammatory cytokines that help reduce inflammation. Hypovitaminosis D can result from various factors, including age, low exposure to sunlight, dietary factors and genetic. Objectives: This study aimed to determine vitamin D levels in chronic low back pain patients. Methods: This research is an observational study with a cross sectional design. The population was all patients with chronic low back pain for more than 3 months. All samples underwent a total Vitamin D 25-OH examination using the Enzyme Linked Fluorescent Assay (ELFA). Results: This study found that the majority of participants are elderly women (73.5%) aged 56-65 years (30.6%). In this study 59.2% of participants had vitamin D deficiency and 30.6% had vitamin D insufficiency. Based on radiological examination, 34.7% had lumbar osteoarthritis. Conclusion: Patient with chronic low back pain had low level of vitamin D. Adequate sunlight exposure, dietary intake, and supplementation when necessary are essential strategies to prevent vitamin D deficiency and its associated health risks in the aging population. Key words: Chronic low back pain, Vitamin