111 research outputs found
A homological interpretation of the transverse quiver Grassmannians
In recent articles, the investigation of atomic bases in cluster algebras
associated to affine quivers led the second-named author to introduce a variety
called transverse quiver Grassmannian and the first-named and third-named
authors to consider the smooth loci of quiver Grassmannians. In this paper, we
prove that, for any affine quiver Q, the transverse quiver Grassmannian of an
indecomposable representation M is the set of points N in the quiver
Grassmannian of M such that Ext^1(N,M/N)=0. As a corollary we prove that the
transverse quiver Grassmannian coincides with the smooth locus of the
irreducible components of minimal dimension in the quiver Grassmannian.Comment: final version, 7 pages, corollary 1.2 has been modifie
Low energy high angular resolution neutral atom detection by means of micro-shuttering techniques: the BepiColombo SERENA/ELENA sensor
The neutral sensor ELENA (Emitted Low-Energy Neutral Atoms) for the ESA
cornerstone BepiColombo mission to Mercury (in the SERENA instrument package)
is a new kind of low energetic neutral atoms instrument, mostly devoted to
sputtering emission from planetary surfaces, from E ~20 eV up to E~5 keV,
within 1-D (2x76 deg). ELENA is a Time-of-Flight (TOF) system, based on
oscillating shutter (operated at frequencies up to a 100 kHz) and mechanical
gratings: the incoming neutral particles directly impinge upon the entrance
with a definite timing (START) and arrive to a STOP detector after a flight
path. After a brief dissertation on the achievable scientific objectives, this
paper describes the instrument, with the new design techniques approached for
the neutral particles identification and the nano-techniques used for designing
and manufacturing the nano-structure shuttering core of the ELENA sensor. The
expected count-rates, based on the Hermean environment features, are shortly
presented and discussed. Such design technologies could be fruitfully exported
to different applications for planetary exploration.Comment: 11 page
Cluster algebras of type
In this paper we study cluster algebras \myAA of type . We solve
the recurrence relations among the cluster variables (which form a T--system of
type ). We solve the recurrence relations among the coefficients of
\myAA (which form a Y--system of type ). In \myAA there is a
natural notion of positivity. We find linear bases \BB of \myAA such that
positive linear combinations of elements of \BB coincide with the cone of
positive elements. We call these bases \emph{atomic bases} of \myAA. These
are the analogue of the "canonical bases" found by Sherman and Zelevinsky in
type . Every atomic basis consists of cluster monomials together
with extra elements. We provide explicit expressions for the elements of such
bases in every cluster. We prove that the elements of \BB are parameterized
by \ZZ^3 via their --vectors in every cluster. We prove that the
denominator vector map in every acyclic seed of \myAA restricts to a
bijection between \BB and \ZZ^3. In particular this gives an explicit
algorithm to determine the "virtual" canonical decomposition of every element
of the root lattice of type . We find explicit recurrence relations
to express every element of \myAA as linear combinations of elements of
\BB.Comment: Latex, 40 pages; Published online in Algebras and Representation
Theory, springer, 201
The potential impact of enhanced hygienic measures during the COVID-19 outbreak on hospital-acquired infections: A pragmatic study in neurological units
Objective: Hospital-acquired infections (HAIs) are frequent complications among acute patients hospitalized in neurological units, especially among those hospitalized for stroke. This study aimed to investigate if enhanced hygienic measures, including the systematic use of personal protective equipment (PPE), determined a decrease in HAI during the recent COVID-19 outbreak in “COVID-free” neurological units. Methods: Patients hospitalized in neurology and stroke units of Policlinico Umberto I Hospital in Rome from March 8, 2020 and discharged prior to May 31, 2020 were included in the study and compared with patients hospitalized during the same period in 2019. Results: A total of 319 patients were included in the study (n = 103 in 2020, n = 216 in 2019). Among patients hospitalized in 2019, the incidence of HAIs was 31.5% (95% confidence interval (CI): 0.25–0.38), compared with 23.3% (95% CI: 0.15–0.32) in 2020 (p = 0.12). Multivariable logistic regression showed that hospitalization during 2020 was independently associated with a lower risk of HAIs (odds ratio: 0.34, 95% CI:0.16–0.71, p = 0.004). Poisson regression models showed that hospitalization during 2020 was also independently associated with both a lower number of HAIs (relative risk [RR]: 0.56, 95% CI:0.38–0.81, p = 0.01) and a lower number of prescribed antibiotics per patient (RR: 0.66, 95% CI: 0.49–0.87, p = 0.02). Conclusion: Our study design provides evidence regarding the impact of stricter hygienic measures, such as increased PPE use, on HAIs. Larger studies are needed to support the extension of preventive measures even after the COVID-19 outbreak in order to limit the occurrence of HAIs
Quadratic differentials as stability conditions
We prove that moduli spaces of meromorphic quadratic differentials with
simple zeroes on compact Riemann surfaces can be identified with spaces of
stability conditions on a class of CY3 triangulated categories defined using
quivers with potential associated to triangulated surfaces. We relate the
finite-length trajectories of such quadratic differentials to the stable
objects of the corresponding stability condition.Comment: 123 pages; 38 figures. Version 2: hypotheses in the main results
mildly weakened, to reflect improved results of Labardini-Fragoso and
coauthors. Version 3: minor changes to incorporate referees' suggestions.
This version to appear in Publ. Math. de l'IHE
Genome sequences of three SARS-CoV-2 P.1 strains identified from patients returning from Brazil to Italy
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of the current coronavirus disease 2019 (COVID-19) pandemic. We report the complete sequences of three SARS-CoV-2 P.1 strains obtained from nasopharyngeal swab specimens from three patients returning from Brazil to Italy
Sustained seizure freedom with adjunctive brivaracetam in patients with focal onset seizures
The maintenance of seizure control over time is a clinical priority in patients with epilepsy. The aim of this study was to assess the sustained seizure frequency reduction with adjunctive brivaracetam (BRV) in real-world practice. Patients with focal epilepsy prescribed add-on BRV were identified. Study outcomes included sustained seizure freedom and sustained seizure response, defined as a 100% and a ≥50% reduction in baseline seizure frequency that continued without interruption and without BRV withdrawal through the 12-month follow-up. Nine hundred ninety-four patients with a median age of 45 (interquartile range = 32–56) years were included. During the 1-year study period, sustained seizure freedom was achieved by 142 (14.3%) patients, of whom 72 (50.7%) were seizure-free from Day 1 of BRV treatment. Sustained seizure freedom was maintained for ≥6, ≥9, and 12 months by 14.3%, 11.9%, and 7.2% of patients from the study cohort. Sustained seizure response was reached by 383 (38.5%) patients; 236 of 383 (61.6%) achieved sustained ≥50% reduction in seizure frequency by Day 1, 94 of 383 (24.5%) by Month 4, and 53 of 383 (13.8%) by Month 7 up to Month 12. Adjunctive BRV was associated with sustained seizure frequency reduction from the first day of treatment in a subset of patients with uncontrolled focal epilepsy
Adjunctive Brivaracetam in Focal Epilepsy: Real-World Evidence from the BRIVAracetam add-on First Italian netwoRk STudy (BRIVAFIRST)
Background: In randomized controlled trials, add-on brivaracetam (BRV) reduced seizure frequency in patients with drug-resistant focal epilepsy. Studies performed in a naturalistic setting are a useful complement to characterize the drug profile. Objective: This multicentre study assessed the effectiveness and tolerability of adjunctive BRV in a large population of patients with focal epilepsy in the context of real-world clinical practice. Methods: The BRIVAFIRST (BRIVAracetam add-on First Italian netwoRk STudy) was a retrospective, multicentre study including adult patients prescribed adjunctive BRV. Patients with focal epilepsy and 12-month follow-up were considered. Main outcomes included the rates of seizure‐freedom, seizure response (≥ 50% reduction in baseline seizure frequency), and treatment discontinuation. The incidence of adverse events (AEs) was also considered. Analyses by levetiracetam (LEV) status and concomitant use of strong enzyme-inducing antiseizure medications (EiASMs) and sodium channel blockers (SCBs) were performed. Results: A total of 1029 patients with a median age of 45 years (33–56) was included. At 12 months, 169 (16.4%) patients were seizure-free and 383 (37.2%) were seizure responders. The rate of seizure freedom was 22.3% in LEV-naive patients, 7.1% in patients with prior LEV use and discontinuation due to insufficient efficacy, and 31.2% in patients with prior LEV use and discontinuation due to AEs (p < 0.001); the corresponding values for ≥ 50% seizure frequency reduction were 47.9%, 29.7%, and 42.8% (p < 0.001). There were no statistically significant differences in seizure freedom and seizure response rates by use of strong EiASMs. The rates of seizure freedom (20.0% vs. 16.6%; p = 0.341) and seizure response (39.7% vs. 26.9%; p = 0.006) were higher in patients receiving SCBs than those not receiving SCBs; 265 (25.8%) patients discontinued BRV. AEs were reported by 30.1% of patients, and were less common in patients treated with BRV and concomitant SCBs than those not treated with SCBs (28.9% vs. 39.8%; p = 0.017). Conclusion: The BRIVAFIRST provided real-world evidence on the effectiveness of BRV in patients with focal epilepsy irrespective of LEV history and concomitant ASMs, and suggested favourable therapeutic combinations
Ionospheric photoelectrons at Venus: Initial observations by ASPERA-4
Abstract We report the detection of electrons due to photo-ionization of atomic oxygen and carbon dioxide in the Venus atmosphere by solar helium 30.4 nm photons. The detection was by the Analyzer of Space Plasma and Energetic Atoms (ASPERA-4) Electron Spectrometer (ELS) on the Venus Express (VEx) European Space Agency (ESA) mission. Characteristic peaks in energy for such photoelectrons have been predicted by Venus atmosphere/ionosphere models. The ELS energy resolution (DE/E$7%) means that these are the first detailed measurements of such electrons. Considerations of ion production and transport in the atmosphere of Venus suggest that the observed photoelectron peaks are due primarily to ionization of atomic oxygen.
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