Занятость в эпоху технологических изменений и цифровизации экономики

Объектом исследования является современный рынок труда. Предмет исследования - занятость в эпоху технологических изменений и цифровизации экономики. Цель выпускной квалификационной работы – выявить специфику занятости в эпоху новых технологических изменений (на примере Китая). - дать характеристику занятости в эпоху технологических изменений и цифровизации экономики. - рассмотреть специфику становления рынка занятости на современном этапе развития экономики. - проанализировать состояние фриланса на европейском и российском рынке труда. В работе проведен анализ актуальных глобальных экономических и технологических тенденций, влияющих на трансформацию рынка труда и формирование новых социально-экономических отношений в условиях становления цифровой экономики.The object of research is the modern labor market. The subject of the study is employment in the era of technological change and the digitalization of the economy. The purpose of the final qualification work is to identify the specifics of employment in the era of new technological changes (for example, China). - to characterize employment in the era of technological change and the digitalization of the economy. - to consider the specifics of the formation of the employment market at the present stage of economic development. The paper analyzes the current global economic and technological trends that affect the transformation of the labor market and the formation of new socio-economic relations in the context of the digital economy

Modern Social Welfare in the Light of the Sustainability Model

The paper presents the analysis of interaction between the social welfare and sustainable development. The aim of this paper is to show that the social development mostly depends on community values that form the pathway of the social movement. It is shown that mankind can influence the future choosing the optimum way of its development. Therefore, it is necessary to appreciate personal aspects of sociogenesis and a mechanism of its functioning, differences between social and natural dynamics. From the authors’ viewpoint, a philosophical understanding of sustainability by means of welfare as a regulation mechanism, is one of approaches to the study of social life and social development. A model of socio-practical man's existence mostly oriented towards satisfaction of needs helps to analyze the relationship between the categories under review. The more so as an ordinary intake of consumer amenities transforms to the instrument of construction od social identity, the sociocultural integration of individual with society. Social welfare is presented as a multiple-factor construct represented by a synthesis of cause and effect. Explication technique, hermeneutical approach, and comparison study are used to clarify basic notions of this research

The hybridization of vocational and organizational and entrepreneurial skills in the activity of the well-being of modern society

This paper considers the problem of the need to transform approaches to organization, business, economic processes and education. The functional dependence between business and social well-being of society is revealed. The relevance of social aspects of entrepreneurial activity is emphasized. Currently, entrepreneurship is seen not only as a process of making a profit, but also as innovation, creativity, generation of ideas and non-standard approaches to activity. In this context, the skills of the entrepreneur acquire a special meaning and are important for specialists in various fields. Entrepreneurship can and should be considered by the organizers of education as a unique opportunity for the integration preparation of students for the implementation of professional - organizational and entrepreneurial activities at the same time. The concept of "hybrid activity" is introduced and the definition of "entrepreneurial skills" for a University student is proposed

Global prevalence and genotype distribution of hepatitis C virus infection in 2015 : A modelling study

Publisher Copyright: © 2017 Elsevier LtdBackground The 69th World Health Assembly approved the Global Health Sector Strategy to eliminate hepatitis C virus (HCV) infection by 2030, which can become a reality with the recent launch of direct acting antiviral therapies. Reliable disease burden estimates are required for national strategies. This analysis estimates the global prevalence of viraemic HCV at the end of 2015, an update of—and expansion on—the 2014 analysis, which reported 80 million (95% CI 64–103) viraemic infections in 2013. Methods We developed country-level disease burden models following a systematic review of HCV prevalence (number of studies, n=6754) and genotype (n=11 342) studies published after 2013. A Delphi process was used to gain country expert consensus and validate inputs. Published estimates alone were used for countries where expert panel meetings could not be scheduled. Global prevalence was estimated using regional averages for countries without data. Findings Models were built for 100 countries, 59 of which were approved by country experts, with the remaining 41 estimated using published data alone. The remaining countries had insufficient data to create a model. The global prevalence of viraemic HCV is estimated to be 1·0% (95% uncertainty interval 0·8–1·1) in 2015, corresponding to 71·1 million (62·5–79·4) viraemic infections. Genotypes 1 and 3 were the most common cause of infections (44% and 25%, respectively). Interpretation The global estimate of viraemic infections is lower than previous estimates, largely due to more recent (lower) prevalence estimates in Africa. Additionally, increased mortality due to liver-related causes and an ageing population may have contributed to a reduction in infections. Funding John C Martin Foundation.publishersversionPeer reviewe

Expression profile of the transient receptor potential (TRP) family in neutrophil granulocytes: evidence for currents through long TRP channel 2 induced by ADP-ribose and NAD

An early key event in the activation of neutrophil granulocytes is Ca(2+) influx. Members of the transient receptor potential (TRP) channel family may be held responsible for this. The aim of the present study is to analyse the expression pattern of TRP mRNA and identify characteristic currents unambiguously attributable to particular TRP channels. mRNA was extracted from human neutrophils, isolated by gradient centrifugation and also by magnetically labelled CD15 antibodies. The presence of mRNA was demonstrated using reverse transcriptase-PCR in neutrophils (controlled to be CD5-negative) as well as in human leukaemic cell line 60 (HL-60) cells, for the following TRP species: the long TRPC2 (LTRPC2), the vanilloid receptor 1, the vanilloid receptor-like protein 1 and epithelial Ca(2+) channels 1 and 2. TRPC6 was specific for neutrophils, whereas only in HL-60 cells were TRPC1, TRPC2, TRPC3, melastatin 1 and melastatin-related 1 found. Patch-clamp measurements in neutrophils revealed non-selective cation currents evoked by intracellular ADP-ribose and by NAD(+). Both these modes of activation have been found to be characteristic of LTRPC2. Furthermore, single-channel activity was resolved in neutrophils and it was indistinguishable from that in LTRPC2-transfected HEK-293 cells. The results provide evidence that LTRPC2 in neutrophil granulocytes forms an entry pathway for Na(+) and Ca(2+), which is regulated by ADP-ribose and the redox state