112 research outputs found

    Veils and Cloaks of Ignorance: Under-used Tools for Conflict Resolution

    Get PDF
    Published in cooperation with the American Bar Association Section of Dispute Resolutio

    Why Does Anyone Mediate if Mediation Risks Psychological Dissatisfaction, Extra Costs and Manipulation? Three Theories Reveal Paradoxes Resolved by Mediator Standards of Ethical Practice

    Get PDF
    Published in cooperation with the American Bar Association Section of Dispute Resolutio

    The Conspiracy Money Machine: Uncovering Telegram's Conspiracy Channels and their Profit Model

    Full text link
    In recent years, major social media platforms have implemented increasingly strict moderation policies, resulting in bans and restrictions on conspiracy theory-related content. To circumvent these restrictions, conspiracy theorists are turning to alternatives, such as Telegram, where they can express and spread their views with fewer limitations. Telegram offers channels -- virtual rooms where only administrators can broadcast messages -- and a more permissive content policy. These features have created the perfect breeding ground for a complex ecosystem of conspiracy channels. In this paper, we illuminate this ecosystem. First, we propose an approach to detect conspiracy channels. Then, we discover that conspiracy channels can be clustered into four distinct communities comprising over 17,000 channels. Finally, we uncover the "Conspiracy Money Machine," revealing how most conspiracy channels actively seek to profit from their subscribers. We find conspiracy theorists leverage e-commerce platforms to sell questionable products or lucratively promote them through affiliate links. Moreover, we observe that conspiracy channels use donation and crowdfunding platforms to raise funds for their campaigns. We determine that this business involves hundreds of donors and generates a turnover of over $90 million

    Colorization and Automated Segmentation of Human T2 MR Brain Images for Characterization of Soft Tissues

    Get PDF
    Characterization of tissues like brain by using magnetic resonance (MR) images and colorization of the gray scale image has been reported in the literature, along with the advantages and drawbacks. Here, we present two independent methods; (i) a novel colorization method to underscore the variability in brain MR images, indicative of the underlying physical density of bio tissue, (ii) a segmentation method (both hard and soft segmentation) to characterize gray brain MR images. The segmented images are then transformed into color using the above-mentioned colorization method, yielding promising results for manual tracing. Our color transformation incorporates the voxel classification by matching the luminance of voxels of the source MR image and provided color image by measuring the distance between them. The segmentation method is based on single-phase clustering for 2D and 3D image segmentation with a new auto centroid selection method, which divides the image into three distinct regions (gray matter (GM), white matter (WM), and cerebrospinal fluid (CSF) using prior anatomical knowledge). Results have been successfully validated on human T2-weighted (T2) brain MR images. The proposed method can be potentially applied to gray-scale images from other imaging modalities, in bringing out additional diagnostic tissue information contained in the colorized image processing approach as described

    White Matter Development in Early Puberty: A Longitudinal Volumetric and Diffusion Tensor Imaging Twin Study

    Get PDF
    White matter microstructure and volume show synchronous developmental patterns in children. White matter volume increases considerably during development. Fractional anisotropy, a measure for white matter microstructural directionality, also increases with age. Development of white matter volume and development of white matter microstructure seem to go hand in hand. The extent to which the same or different genetic and/or environmental factors drive these two aspects of white matter maturation is currently unknown. We mapped changes in white matter volume, surface area and diffusion parameters in mono- and dizygotic twins who were scanned at age 9 (203 individuals) and again at age 12 (126 individuals). Over the three-year interval, white matter volume (+6.0%) and surface area (+1.7%) increased, fiber bundles expanded (most pronounced in the left arcuate fasciculus and splenium), and fractional anisotropy increased (+3.0%). Genes influenced white matter volume (heritability ∼85%), surface area (∼85%), and fractional anisotropy (locally 7% to 50%) at both ages. Finally, volumetric white matter growth was negatively correlated with fractional anisotropy increase (r = –0.62) and this relationship was driven by environmental factors. In children who showed the most pronounced white matter growth, fractional anisotropy increased the least and vice-versa. Thus, white matter development in childhood may reflect a process of both expansion and fiber optimization

    Differential Development of Human Brain White Matter Tracts

    Get PDF
    Neuroscience is increasingly focusing on developmental factors related to human structural and functional connectivity. Unfortunately, to date, diffusion-based imaging approaches have only contributed modestly to these broad objectives, despite the promise of diffusion-based tractography. Here, we report a novel data-driven approach to detect similarities and differences among white matter tracts with respect to their developmental trajectories, using 64-direction diffusion tensor imaging. Specifically, using a cross-sectional sample comprising 144 healthy individuals (7 to 48 years old), we applied k-means cluster analysis to separate white matter voxels based on their age-related trajectories of fractional anisotropy. Optimal solutions included 5-, 9- and 14-clusters. Our results recapitulate well-established tracts (e.g., internal and external capsule, optic radiations, corpus callosum, cingulum bundle, cerebral peduncles) and subdivisions within tracts (e.g., corpus callosum, internal capsule). For all but one tract identified, age-related trajectories were curvilinear (i.e., inverted ‘U-shape’), with age-related increases during childhood and adolescence followed by decreases in middle adulthood. Identification of peaks in the trajectories suggests that age-related losses in fractional anisotropy occur as early as 23 years of age, with mean onset at 30 years of age. Our findings demonstrate that data-driven analytic techniques may be fruitfully applied to extant diffusion tensor imaging datasets in normative and neuropsychiatric samples

    CNS involvement in OFD1 syndrome: A clinical, molecular, and neuroimaging study

    Get PDF
    corecore