124 research outputs found
About the determination of critical exponents related to possible phase transitions in nuclear fragmentation
We introduce a method based on the finite size scaling assumption which
allows to determine numerically the critical point and critical exponents
related to observables in an infinite system starting from the knowledge of the
observables in finite systems. We apply the method to bond percolation in 2
dimensions and compare the results obtained when the bond probability p or the
fragment multiplicity m are chosen as the relevant parameter.Comment: 12 pages, TeX, 4 figure
Early onset pauciarticular arthritis is the major risk factor for naproxen-induced pseudoporphyria in juvenile idiopathic arthritis
Pseudoporphyria (PP) is characterized by skin fragility, blistering and scarring in sun-exposed skin areas without abnormalities in porphyrin metabolism. The phenylpropionic acid derivative group of nonsteroidal anti-inflammatory drugs, especially naproxen, is known to cause PP. Naproxen is currently one of the most prescribed drugs in the therapy of juvenile idiopathic arthritis (JIA). The prevalence of PP was determined in a 9-year retrospective study of children with JIA and associated diseases. In addition, we prospectively studied the incidence of PP in 196 patients (127 girls and 69 boys) with JIA and associated diseases treated with naproxen from July 2001 to March 2002. We compared these data with those from a matched control group with JIA and associated diseases not treated with naproxen in order to identify risk factors for development of PP. The incidence of PP in the group of children taking naproxen was 11.4%. PP was particularly frequent in children with the early-onset pauciarticular subtype of JIA (mean age 4.5 years). PP was associated with signs of disease activity, such as reduced haemoglobin (<11.75 g/dl), and increased leucocyte counts (>10,400/ÎŒl) and erythocyte sedimentation rate (>26 mm/hour). Comedications, especially chloroquine intake, appeared to be additional risk factors. The mean duration of naproxen therapy before the onset of PP was 18.1 months, and most children with PP developed their lesions within the first 2 years of naproxen treatment. JIA disease activity seems to be a confounding factor for PP. In particular, patients with early-onset pauciarticular JIA patients who have significant inflammation appear to be prone to developing PP upon treatment with naproxen
Breakup Conditions of Projectile Spectators from Dynamical Observables
Momenta and masses of heavy projectile fragments (Z >= 8), produced in
collisions of 197Au with C, Al, Cu and Pb targets at E/A = 600 MeV, were
determined with the ALADIN magnetic spectrometer at SIS. An analysis of
kinematic correlations between the two and three heaviest projectile fragments
in their rest frame was performed. The sensitivity of these correlations to the
conditions at breakup was verified within the schematic SOS-model. The data
were compared to calculations with statistical multifragmentation models and to
classical three-body calculations. Classical trajectory calculations reproduce
the dynamical observables. The deduced breakup parameters, however, differ
considerably from those assumed in the statistical multifragmentation models
which describe the charge correlations. If, on the other hand, the analysis of
kinematic and charge correlations is performed for events with two and three
heavy fragments produced by statistical multifragmentation codes, a good
agreement with the data is found with the exception that the fluctuation widths
of the intrinsic fragment energies are significantly underestimated. A new
version of the multifragmentation code MCFRAG was therefore used to investigate
the potential role of angular momentum at the breakup stage. If a mean angular
momentum of 0.75/nucleon is added to the system, the energy fluctuations
can be reproduced, but at the same time the charge partitions are modified and
deviate from the data.
PACS numbers: 25.70.Mn, 25.70.Pq, 25.75.Ld, 25.75.-qComment: 38 pages, RevTeX with 21 included figures; Also available from
http://www-kp3.gsi.de/www/kp3/aladin_publications.htm
An overview of physics teacher professional development activities organized within the Italian PLS-Physics plan over the past five years
The Italian PLS-"Piano Lauree Scientifiche"project has among its objectives the improvement of school-university cooperation, with a special emphasis on in-service teacher professional development. In pursuit of such goal, growing resources and an increasing effort to strengthen the collaboration with schools have been employed in the past years. A working group within the physics section of the PLS project has developed a questionnaire to inquire about teacher formation activities organized during the past five years. After extensive revision and testing, the university network of PLS-Physics was asked to fill the questionnaire. The resulting data from 139 initiatives provides an interesting perspective on the kind of activities, organizational choices and educational priorities for teacher professional development within the PLS-physics project
Pion radii in nonlocal chiral quark model
The electromagnetic radius of the charged pion and the transition radius of
the neutral pion are calculated in the framework of the nonlocal chiral quark
model. It is shown in this model that the contributions of vector mesons to the
pion radii are noticeably suppressed in comparison with a similar contribution
in the local Nambu--Jona-Lasinio model. The form-factor for the process
gamma*pi+pi- is calculated for the -1 GeV^2<q^2<1.6 GeV^2. Our results are in
satisfactory agreement with experimental data.Comment: 7 pages, 7 figure
Isotopic Dependence of the Nuclear Caloric Curve
The A/Z dependence of projectile fragmentation at relativistic energies has
been studied with the ALADIN forward spectrometer at SIS. A stable beam of
124Sn and radioactive beams of 124La and 107Sn at 600 MeV per nucleon have been
used in order to explore a wide range of isotopic compositions. Chemical
freeze-out temperatures are found to be nearly invariant with respect to the
A/Z of the produced spectator sources, consistent with predictions for expanded
systems. Small Coulomb effects (\Delta T \approx 0.6 MeV) appear for residue
production near the onset of multifragmentation.Comment: 11 pages, 3 figures, accepted for publ. in Phys. Rev. Let
Tracing a phase transition with fluctuations of the largest fragment size: Statistical multifragmentation models and the ALADIN S254 data
A phase transition signature associated with cumulants of the largest
fragment size distribution has been identified in statistical
multifragmentation models and examined in analysis of the ALADIN S254 data on
fragmentation of neutron-poor and neutron-rich projectiles. Characteristics of
the transition point indicated by this signature are weakly dependent on the
A/Z ratio of the fragmenting spectator source. In particular, chemical
freeze-out temperatures are estimated within the range 5.9 to 6.5 MeV. The
experimental results are well reproduced by the SMM model.Comment: 7 pages, 3 figures, Proceedings of the International Workshop on
Multifragmentation and Related Topics (IWM2009), Catania, Italy, November
2009
The Rho GDI Rdi1 regulates Rho GTPases by distinct mechanisms
© 2008 by The American Society for Cell Biology. Under the License and Publishing Agreement, authors grant to the general public, effective two months after publication of (i.e.,. the appearance of) the edited manuscript in an online issue of MBoC, the nonexclusive right to copy, distribute, or display the manuscript subject to the terms of the Creative CommonsâNoncommercialâShare Alike 3.0 Unported license (http://creativecommons.org/licenses/by-nc-sa/3.0).The small guanosine triphosphate (GTP)-binding proteins of the Rho family are implicated in various cell functions, including establishment and maintenance of cell polarity. Activity of Rho guanosine triphosphatases (GTPases) is not only regulated by guanine nucleotide exchange factors and GTPase-activating proteins but also by guanine nucleotide dissociation inhibitors (GDIs). These proteins have the ability to extract Rho proteins from membranes and keep them in an inactive cytosolic complex. Here, we show that Rdi1, the sole Rho GDI of the yeast Saccharomyces cerevisiae, contributes to pseudohyphal growth and mitotic exit. Rdi1 interacts only with Cdc42, Rho1, and Rho4, and it regulates these Rho GTPases by distinct mechanisms. Binding between Rdi1 and Cdc42 as well as Rho1 is modulated by the Cdc42 effector and p21-activated kinase Cla4. After membrane extraction mediated by Rdi1, Rho4 is degraded by a novel mechanism, which includes the glycogen synthase kinase 3ÎČ homologue Ygk3, vacuolar proteases, and the proteasome. Together, these results indicate that Rdi1 uses distinct modes of regulation for different Rho GTPases.Deutsche Forschungsgemeinschaf
Multiplicity correlations of intermediate-mass fragments with pions and fast protons in 12C + 197Au
Low-energy pi+ (E < 35 MeV) from 12C+197Au collisions at incident energies
from 300 to 1800 MeV per nucleon were detected with the Si-Si(Li)-CsI(Tl)
calibration telescopes of the INDRA multidetector. The inclusive angular
distributions are approximately isotropic, consistent with multiple
rescattering in the target spectator. The multiplicity correlations of the
low-energy pions and of energetic protons (E > 150 MeV) with intermediate-mass
fragments were determined from the measured coincidence data. The deduced
correlation functions 1 + R \approx 1.3 for inclusive event samples reflect the
strong correlations evident from the common impact-parameter dependence of the
considered multiplicities. For narrow impact-parameter bins (based on
charged-particle multiplicity), the correlation functions are close to unity
and do not indicate strong additional correlations. Only for pions at high
particle multiplicities (central collisions) a weak anticorrelation is
observed, probably due to a limited competition between these emissions.
Overall, the results are consistent with the equilibrium assumption made in
statistical multifragmentation scenarios. Predictions obtained with
intranuclear cascade models coupled to the Statistical Multifragmentation Model
are in good agreement with the experimental data.Comment: 9 pages, 11 figures, subm. to EPJ
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