4,330 research outputs found

    Engineering learning of sustainable product lifecycle through CDIO

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    Sustainable development is an optional CDIO (Conceive, Design, Implement, Operate) standard in the engineering curriculum, however, due to the impact of climate change on society and the environment, sustainability is now seen as a crucial aspect of learning. Engineering has contributed to climate change through non-sustainable solutions, so it is important to implement a sustainable CDIO standard in the engineering curriculum. In the UK, the Engineering Council already requires engineering-accredited courses to embed sustainability into the engineering curriculum, learning, practice and assessment following the UNESCO sustainability goals. This means that the engineering curriculum is required to provide learning opportunities for students to engineer sustainable solutions that are fit for all of society. This paper illustrates how the optional CDIO standard: sustainable development has been implemented in a second-year capstone project module The module challenges students to research and develop a low-carbon footprint product for World Rugby The module placed learning emphasis on a diamond TQM+ paradigm (Time, Quality, Management, Sustainability, Health & Safety) and challenged students to consider environmental impact and circular economy solutions. The paper reports on student learning, challenges, and successes in satisfying this diamond TQM+ paradigm to engineer sustainable rugby equipment (products, clothing, footwear, PPE) solutions and opportunities for further student learning development

    Tinjauan Hukum Islam terhadap Pelaksanaan Pidana Kurungan bagi Anak Nakal di Rutan Anak Blitar

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    Among the criminal problem that are faced by society today is children crimes and violations, which legally referred to as "child crime". Consequently, they must be held accountable through a judicial process that can lead to imprisonment. In Indonesia, one of the places for child incarceration is in the Children's Correction Center (LPA) of Blitar. The study aims to determine the implementation of imprisonment policy for children in LPA Blitar and the Islamic criminal law's perspective. The results of this study concluded that the criminal justice process for children criminals in LPA Blitar prevails under the current law. As for the efforts of the Blitar LPA in its implementation of the policy is to provide guidance and education in a best and fair manner tailored with the evolution of children's psychology. In Islamic law, there is no prohibition about children's punishment as long as the child has passed the age of baligh, but must prioritize the education and mental development of the child. It is in line with sharia law and relevant law in Indonesi

    Pengaruh Pelapukan Batulempung Formasi Subang terhadap beberapa Sifat Keteknikannya Guna Menunjang Efektivitas Pemilihan Desain Perkuatan Lereng

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    Dalam makalah ini dibahas karakteristik pelapukan batulempung Formasi Subang dalam kaitannya dengan sistem klasifikasi derajat pelapukan batuan dan perubahan nilai beberapa sifat keteknikannya. Lokasi pengamatan lapangan dan pengambilan contoh batuan dilaksanakan di daerah Karawang Selatan, Jawa Barat, karena kehadiran jenis batuan ini menempati wilayah yang cukup luas. Secara umum batulempung Formasi Subang dapat dibedakan atas enam zona yang mencerminkan perbedaan derajat pelapukannya. Hasil pengujian beberapa sifat keteknikan yang merupakan parameter dasar dalam analisis kestabilan lereng, seperti berat isi, kohesi, dan sudut geser dalam, memperlihatkan adanya hubungan yang berarti terhadap perubahan derajat pelapukannya. Maka, dengan mengetahui variasi derajat pelapukan batulempung Formasi Subang diharapkan perencanaan atau pemilihan desain (jenis) perkuatan lereng dapat dilakukan secara lebih tepat dan eifisien.Influence of Weathering in Claystone of Subang Formation on Some Engineering Properties to Effectively Support in Choosing of Slope- Reinforcement DesignThis paper presents weathering characteristics of claystone of Subang Formation in relation to weathering grade classification system and changes of some engineering properties. The field observation and rock-soil sampling were located at Southern Karawang area, West Java, where the claystone is distributed widely. Generally, claystone of Subang Formation can be classified into six degrees of weathering. The examination results of some engineering properties, such as unit weight, cohesion, and internal friction angle as basic parameters of slope stability analysis, indicate good relationship with the change of weathering grade. As an implication, by knowing various weathering grades, the planning or choosing of slope-reinforcement-design will be more effective and efficient.

    Efficacy of erythropoietin-pretreated mesenchymal stem cells in murine burn wound healing: possible in vivo transdifferentiation into keratinocytes

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    Background: Stem cells have shown promising potential to treat burn wounds. Erythropoietin was capable of promoting in vitro transdifferentiation of mesenchymal stem cells (MSCs). The aim of the study was to investigate possible role of erythropoietin-pretreated mesenchymal stem cells (EPOa/MSCs) in burn wounds healing and to evaluate its in vivo differentiation into keratinocytes. Materials and methods: Forty rats were utilised in this study divided into four groups (n = 10 for each). Control group (I), burn group (II), burn + MSCs, group (III), burn + EPOa/MSCs. 1 × 106 cells were injected locally for each 1 cm2 of burn areas. Burn areas were followed-up morphologically. After 21 days of the experiment, the rats were euthanised, skin specimens were assessed biochemically, histologically and immunohistochemically. Results: EPOa/MSCs enhanced significantly (p < 0.05) burn wound vimentin gene expression and level of interleukin (IL)-10 while decreased IL-1 and COX2 as compared to the burn group. Histologically, EPOa/MSCs improved epithelialisation despite stem cells’ differentiation into keratinocytes was rarely detected by PKH26 red fluorescence. EPOa/MSCs promoted angiogenesis as detected by significant increase in VEGF and PDGF immunoexpression as compared to burn group. Conclusions: EPOa/MSCs may improve burn wound healing, probably through anti-inflammatory, immunomodulatory and angiogenic action. However, in vivo transdifferentiation into keratinocytes was rarely detected
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