1,911 research outputs found

    On the Large Time Behavior of Solutions of Hamilton-Jacobi Equations Associated with Nonlinear Boundary Conditions

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    In this article, we study the large time behavior of solutions of first-order Hamilton-Jacobi Equations, set in a bounded domain with nonlinear Neumann boundary conditions, including the case of dynamical boundary conditions. We establish general convergence results for viscosity solutions of these Cauchy-Neumann problems by using two fairly different methods : the first one relies only on partial differential equations methods, which provides results even when the Hamiltonians are not convex, and the second one is an optimal control/dynamical system approach, named the "weak KAM approach" which requires the convexity of Hamiltonians and gives formulas for asymptotic solutions based on Aubry-Mather sets

    A global multicenter study on reference values: 2. Exploration of sources of variation across the countries.

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    This global multicenter study on reference values (RVs) allowed us to explore biological sources of variation (SVs) of RVs across the world.As described in the first part of this paper, RVs of 50 major analytes from 13,396 healthy individuals living in 12 countries were obtained. Analyzed in this study were 23 clinical chemistry analytes and 8 analytes measured by immunoturbidimetry. Multiple regression analysis was performed for each gender, country by country, analyte by analyte, by setting four major SVs (age, BMI, and levels of drinking and smoking) as a fixed set of explanatory variables. For analytes with skewed distributions, log-transformation was applied. The association of each source of variation with RVs was expressed as partial correlation coefficient (rp).Obvious gender and age-related changes in the RVs were observed in many analytes, almost consistently between countries. Compilation of age-related change profiles of RVs after adjusting for between-country differences revealed peculiar patterns specific to each analyte. Judged fromrp, BMI related changes were observed in many nutritional and inflammatory markers in almost all countries. However, the slope of linear BMI vs. RV relationship differed greatly among countries for some analytes. Alcohol and smoking-related changes were observed less conspicuously in a limited number of analytes.Features of sex, age, alcohol, and smoking-related changes in RVs of major analytes were almost comparable worldwide. The finding of differences in BMI-related changes among countries in some analytes is quite relevant to understanding ethnic differences in susceptibility to nutritionally related diseases

    Different disk structures in the hexagonal columnar mesophases of 2,3-dicyano-6,7,10,11-tetraalkoxy-1,4-diazatriphenylenes and 2,3-dicyano-6,7,10,11-tetraalkoxytriphenylenes

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    This is an electronic version of an article published in Liquid Crystals. 34(3): 401-410 (2007). "Liquid Crystals" is available online at: http://www.informaworld.com/openurl?genre=article&issn=0267-8292&volume=34&issue=3&spage=401ArticleLIQUID CRYSTALS. 34(1-3): 401-410 (2007)journal articl

    Measurement of Single and Double Spin-Flip Probabilities in Inelastic Deuteron Scattering on 12C at 270 MeV

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    The deuteron single and double spin-flip probabilities, S1 and S2, have been measured for the 12C(pol{d},pol{d}') reaction at Ed = 270 MeV for an excitation energy range between 4 and 24 MeV and a scattering angular range between Theta_lab = 2.5 and 7.5 deg. The extracted S1 exhibits characteristic values depending on the structure of the excited state. The S2 is close to zero over the measured excitation energy range. The SFP angular distribution data for the 2+ (4.44 MeV) and 1+ (12.71 MeV) states are well described by the microscopic DWIA calculations

    Involvement of (pro)renin receptor in the glomerular filtration barrier

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    (Pro)renin receptor-bound prorenin not only causes the generation of angiotensin II via the nonproteolytic activation of prorenin, it also activates the receptor’s own intracellular signaling pathways independent of the generated angiotensin II. Within the kidneys, the (pro)renin receptor is not only present in the glomerular mesangium, it is also abundant in podocytes, which play an important role in the maintenance of the glomerular filtration barrier. Recent in vivo studies have demonstrated that the overexpression of the (pro)renin receptor to a degree similar to that observed in hypertensive rat kidneys leads to slowly progressive nephropathy with proteinuria. In addition, the handle region peptide, which acts as a decoy peptide and competitively inhibits the binding of prorenin to the receptor, is more beneficial than an angiotensin-converting enzyme inhibitor with regard to alleviating proteinuria and glomerulosclerosis in experimental animal models of diabetes and essential hypertension. Thus, the (pro)renin receptor may be upregulated in podocytes under hypertensive conditions and may contribute to the breakdown of the glomerular filtration barrier

    The performance of thin NaI(Tl) scintillator plate for dark matter search

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    A thin (0.05cm) and wide area (5cmX5cm) NaI(Tl) scintillator was developed. The performance of the thin NaI(Tl) plate, energy resolution, single photoelectron energy and position sensitivity were tested. An excellent energy resolution of 20% (FWHM) at 60keV was obtained. The single photoelectron energy was calculated to be approximately 0.42 0.02keV. Position information in the 5cmx5cm area of the detector was also obtained by analyzing the ratio of the number of photons collected at opposite ends of the detector. The position resolution was obtained to be 1cm (FWHM) in the 5cmx5cm area.Comment: 10 pages. Accepted to Journal of Physical Society of Japa

    Three-body dN interaction in the analysis of the 12C(pol_d,d') reaction at 270 MeV

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    We have measured the cross sections and analyzing powers Ay and Ayy for the elastic and inelastic scattering of deuterons from the 0+(g.s.), 2+(4.44 MeV), 3-(9.64 MeV), 1+(12.71 MeV), and 2-(18.3 MeV) states in 12C at an incident energy of 270 MeV. The data are compared with microscopic distorted-wave impulse approximation calculations where the projectile-nucleon effective interactionis taken from the three-nucleon t-matrix given by rigorous Faddeev calculations presently available at intermediate energies. The agreement between theory and data compares well with that for the (p,p') reactions at comparable incident energies/nucleon.Comment: 17 pages, 3 Postscript figure

    Complete Set of Polarization Transfer Observables for the 12C(p,n)^{12}{\rm C}(p,n) Reaction at 296 MeV and 0^{\circ}

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    A complete set of polarization transfer observables has been measured for the 12C(p,n)^{12}{\rm C}(p,n) reaction at Tp=296MeVT_p=296 {\rm MeV} and θlab=0\theta_{\rm lab}=0^{\circ}. The total spin transfer Σ(0)\Sigma(0^{\circ}) and the observable f1f_1 deduced from the measured polarization transfer observables indicate that the spin--dipole resonance at Ex7MeVE_x \simeq 7 {\rm MeV} has greater 22^- strength than 11^- strength, which is consistent with recent experimental and theoretical studies. The results also indicate a predominance of the spin-flip and unnatural-parity transition strength in the continuum. The exchange tensor interaction at a large momentum transfer of Q3.6fm1Q \simeq 3.6 {\rm fm}^{-1} is discussed.Comment: 4 pages, 4 figure
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