170 research outputs found

    Regions and the Territorial Cohesion

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    Territorial cohesion is an important target of European Union, constantly promoted by its institutions and their representatives. In the context of the Europe 2020 strategy, one of the most important support documents, the region represents a very important issue, being considered to be the key to its successfulness. The region is seen as a support for the smart growth and all the operational policy concepts try to make use of the spatial potential, by taking better account of the territorial specificities. Two main questions play attention: the need to transform the present-day developmental regions into administrative ones is a priority? What kind of regionalization it must to be promoted? Correlating these issues with already defined territorial cohesion, the administrative region is a real tool for the future territorial development. The experience of the last 14 years asks urgently the building of a new territorial administrative reform, giving competences to regions. For instant, each development region is a construction resulted from a free association of the counties. Their role in the regional development is much reduced one, because their regional councils are not elected; decisions taken at this level are consultative for the social, economical, cultural or political actors

    DYNAMICS OF SPATIAL COMPLEXITY IN DISADVANTAGED SOCIO-ECONOMIC AREAS

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    This paper examines the relevance of spatial complexity concept, especially looking to the dynamics, applied to the disadvantaged socio-economic areas. Relations between different territorial sub-systems have a strong spatial component. Socio-economic sub-systems are connected and interrelated causally but this trend accumulates differentiated increases that are transmitted to spatial complexity. Spatial complexity is not synonymous with economic development unless specialization is achieved only in the primary sector. On the other hand, forced diversification of economic activities achieved by a centralized political system is not a way out of the vicious circle of underdevelopment. Using some relevant variables to measure the socio-economic territorial discrepancies, were delineated the disadvantaged areas. The deep analysis it was made on three selected socio-economic areas, located in different geographical contexts. Dynamics of spatial complexity of rural areas is a relative one, contradictory, with reducing trends of. These tendencies are defined by a subsistence dominant agriculture, accompanied by an incipient services sector

    Correlation between body mass index and the results of the treatment of iron deficiency anemia in pregnant women

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    Department of Pharmacology and Clinical Pharmacology, Nicolae Testemitsanu State University of Medicine and Pharmacy, Chisinau, the Republic of MoldovaBackground: Iron deficiency anemia (IDA) is a hematologic syndrome characterized by the deregulation of hemoglobin synthesis due to iron deficiency. During pregnancy, there is an increase of about six times of iron. A correlation between body mass index (BMI) and hemoglobin (Hb) in pregnant women with IDA during the treatment with “Sorbifer Durules” (SD) was evaluated. Material and methods: A retrospective, cohort study. 40 medical cards of pregnant women diagnosed with IDA during the pregnancy and who were treated with SD: one tablet 2 times per day, were studied. The BMI and Hb levels were assessed in each trimester of pregnancy. The dynamic of Hb values was determined: ΔHb II-I – the difference between Hb values of the 2nd and of the 1st trimesters, ΔHbIII-II – the difference between Hb values of the 3rd and of the 2nd trimesters. Statistics: Pearson’s correlation coefficient. Results: IDA was diagnosed in 15 out of 40 pregnant women in the 1st trimester of pregnancy (IDA1), in 19 – in the 2nd trimester (IDA2), in 6 – in the 3rd trimester (IDA3). 7 pregnant IDA1 with normal body weight (BMI = 18,5-25 kg/m2) had ΔHbII-I=14,28 g/l, 8 pregnant IDA1 with grade I obesity (BMI=30-35 kg/m2) had ΔHbII-I=26,12 g/l. Pearson correlation coefficient between BMI in the 1st trimester of pregnancy and ΔHbII-I in pregnant IDA1: r=+0,617, p=0,014. The associations between BMI and ΔHb in pregnant IDA2 and IDA3 were negligible. Conclusions: There is a substantial and significant association between BMI in pregnant women who developed IDA in the 1st trimester and Hb increase during the treatment with SD

    Influence of surface roughness on burner characteristics and combustion performance of AM combustors

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    The transformation of the fossil fuel-based energy sector to a resilient, secure, and environmentally friendly equivalent, could potentially be achieved through the utilisation of “green” hydrogen-based energy. Although the introduction of pure, or blended hydrogen fuels to the power generation sector is associated with serious operability issues, novel manufacturing methods including Additive Manufacturing (AM) could assist in addressing such issues and facilitate the transformation of the power generation industry. Apart from the environmental, operational, and economic benefits afforded through AM, the latter is capable of delivering “manufacturable” surface roughness, enhancing the production efficiency of components and potentially improving gas turbine performance. This thesis aims to gain an understanding, through CFD and empirical investigations, of the impact of surface roughness on aerodynamics, combustion performance and emissions of a generic AM combustor characteristic of practical burners utilising conventional methane, pure hydrogen and an energy balanced mixture of methane and hydrogen. Parametric combustion studies of the selected fuel types are conducted in a new generic swirl burner under atmospheric pressure and elevated temperature conditions, relevant to practical burner designs. A system comprising of several diagnostic tools has been developed and operated to accommodate the empirical investigation of surface roughness and deliver the relevant research objectives. Additionally, a computational study of the impact of surface roughness on the resultant aerodynamic flow field has also been designed and implemented. The effectiveness of the employed computational method was supported by the experimental results. The analysis of the empirical and computational findings of the present thesis, aims to build upon the existing knowledge concerning the influence of surface roughness on burner characteristics and combustion phenomena, informing gas turbine manufacturers on potential advantages and economic incentives of AM burners. With increasing surface roughness, the flame location is shifted towards the centreline of the burner, due to the alteration of the aerodynamic flow field. This observation is further supported computationally. The trend is consistent under any fuel type studied and did not influence the NOx emissions or the burner stability envelopes

    Acute toxicity of profetur and metiferon

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    Was studied the acute toxicity of substances metiferon and profetur by intraperitoneal administration in rats and mice. Preparations were introduced in different doses to determine the maximum tolerated dose and lethal absolute dose. At high doses of profetur animals became inhibited, apathetic, didn't react to stimuli audible and tactile intensity initially moderate and then high, caused tonic seizures. At high doses of metiferon, animals showed signs of peritoneal irritation, aggression, high excitability, tonic seizures, and stereotyped movements. Median lethal dose (LD50) determination was made according to the method of Kerber. LD50 of profetur is 630 mg/kg for mice. LD50 of metiferon is 520 mg/kg for mice and 480 mg/kg for rats

    Educational support in an Expanded Learning Time initiative: Optimizing its components to promote inclusive education

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    Expanded Learning Time (ELT) measures have been implemented internationally to reduce the likelihood of academic underachievement among students at risk. The goal of this article is to examine the components of an ELT initiative aimed at supporting students at risk of academic failure in order to optimize the components that can improve its use and organization. Through a mixed method research approach, we have analyzed the experiences of 1,786 5th through 10th graders, 238 teachers and 126 instructors of a city-wide after-school initiative in Spain. This within-group study examines the design of the support, the environment, and the interactions between stakeholders as key components to optimize this support and promote equity. The results show which support components are related to greater support use. The results also suggest understanding these measures as additional support placed within an enriched support network. Implications for practice, research and policy towards this type of initiative are also discussed
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