An Archaeological Survey of Friedrich Park, Bexar County, Texas

An archaeological survey of the Friedrich Park property, in north Bexar County, Texas, was conducted by the Center for Archaeological Research, University of Texas at San Antonio. These investigations were made at the request of the Parks and Recreation Department of the City of San Antonio. The field work was undertaken by the authors during the months of May and July, 1975. All field activities were carried out under the terms of State Antiquities Permit No. 83. Friedrich Park is located in northern Bexar County, approximately 10 miles north of IH 410 and west of IH 10. The specific area examined encompassed a total of approximately 200 acres. The purpose of the survey was to ascertain the existence of any historic or archaeological resources which should be preserved in the interest of the park. Once resources were found, the task of the survey team was to evaluate the nature and the significance of the sites

Primary skin fibroblasts as a model of Parkinson's disease

Parkinson's disease is the second most frequent neurodegenerative disorder. While most cases occur sporadic mutations in a growing number of genes including Parkin (PARK2) and PINK1 (PARK6) have been associated with the disease. Different animal models and cell models like patient skin fibroblasts and recombinant cell lines can be used as model systems for Parkinson's disease. Skin fibroblasts present a system with defined mutations and the cumulative cellular damage of the patients. PINK1 and Parkin genes show relevant expression levels in human fibroblasts and since both genes participate in stress response pathways, we believe fibroblasts advantageous in order to assess, e.g. the effect of stressors. Furthermore, since a bioenergetic deficit underlies early stage Parkinson's disease, while atrophy underlies later stages, the use of primary cells seems preferable over the use of tumor cell lines. The new option to use fibroblast-derived induced pluripotent stem cells redifferentiated into dopaminergic neurons is an additional benefit. However, the use of fibroblast has also some drawbacks. We have investigated PARK6 fibroblasts and they mirror closely the respiratory alterations, the expression profiles, the mitochondrial dynamics pathology and the vulnerability to proteasomal stress that has been documented in other model systems. Fibroblasts from patients with PARK2, PARK6, idiopathic Parkinson's disease, Alzheimer's disease, and spinocerebellar ataxia type 2 demonstrated a distinct and unique mRNA expression pattern of key genes in neurodegeneration. Thus, primary skin fibroblasts are a useful Parkinson's disease model, able to serve as a complement to animal mutants, transformed cell lines and patient tissues

Flora of Nature Park Papuk

Papuk je proglašen Parkom prirode 23. travnja 1999. godine. Sadrži brojna prirodna bogatstva; biljnog i životinjskog svijeta. U svom seminaru sam se osvrnula na floru Parka prirode Papuk, na najugroženije biljne vrste, te na zaštićene biljne vrste kako bih ih sama bolje upoznala ali i upozorila na važnost očuvanja ovog bogatstva. Razlog ugroženosti ovih vrsta je ponajviše branje u dekorativne svrhe i prenamjena staništa, sječa šuma i slično. Radi iznimnog bogatstva biljnog i životinjskog svijeta mnogo vrsta je zaštićeno kako bi se očuvala biološka raznolikost. Prirodne ljepote koje se mogu vidjeti u Parku prirode Papuk jednostavno je nemoguće opisati, to se mora vidjeti i doživjeti.Papuk was declared a Nature park 23rd april 1999. It contains many natural resources, flora and fauna. In my seminar, I commented on the flora Papuk Nature Park, the most endangered species, and protected species that would be better met alone and warned of the importance of preserving this wealth. The reason these types of threat is mainly for decorative purposes, harvesting and conversion of habitats, forest cutting etc. In order to exceptional wealth of flora and fauna many species is protected to maintain biological diversity. Natural beauty that can be seen in the nature park Papuk it is simply impossible to describe, it must be seen and experienced

Competition between structural distortion and magnetic moment formation in fullerene C20_{20}

We investigated the effect of on-site Coulomb interactions on the structural and magnetic ground state of the fullerene C$_{20}$ based on density-functional-theory calculations within the local density approximation plus on-site Coulomb corrections (LDA+$U$). The total energies of the high symmetry ($I_{h}$) and distorted ($D_{3d}$) structures of C$_{20}$ were calculated for different spin configurations. The ground state configurations were found to depend on the forms of exchange-correlation potentials and the on-site Coulomb interaction parameter $U$, reflecting the subtle nature of the competition between Jahn-Teller distortion and magnetic instability in fullerene C$_{20}$. While the non-magnetic state of the distorted $D_{3d}$ structure is robust for small $U$, a magnetic ground state of the undistorted $I_{h}$ structure emerges for $U$ larger than 4 eV when the LDA exchange-correlation potential is employed.Comment: 4 figures, 1 tabl

Test of a Novel Streptococcus pneumoniae Serotype 6C Type Specific Polyclonal Antiserum (Factor Antiserum 6d) and Characterisation of Serotype 6C Isolates in Denmark

<p>Abstract</p> <p>Background</p> <p>In 2007, Park <it>et al. </it>identified a novel serotype among <it>Streptococcus pneumoniae </it>serogroup 6 which they named serotype 6C. The aim of this study was to evaluate with the Neufeld test a novel <it>S. pneumoniae </it>serotype 6C type specific polyclonal antiserum. In addition, serotype 6C isolates found in Denmark in 2007 and 2008 as well as eight old original serotype 6A isolates were characterised.</p> <p>Methods</p> <p>In this study, 181 clinical <it>Streptococcus pneumoniae </it>isolates from Denmark 2007 and 2008 were examined; 96 isolates had previously been typed as serotype 6A and 85 as serotype 6B. In addition, eight older isolates from 1952 to 1987, earlier serotyped as 6A, were examined. Serotype 6C isolates were identified by PCR and serotyping with the Neufeld test using the novel type specific polyclonal antiserum, factor antiserum 6 d, in addition to factor antisera 6b, 6b* (absorbed free for cross-reactions to serotype 6C) and 6c. All antisera are commercially available and antiserum 6b obtained from the supplier after 1 January 2009 is antiserum 6b*. All serotype 6C isolates were further characterised using multi-locus sequence typing.</p> <p>Results</p> <p>When retesting all 96 original serotype 6A isolates by PCR and the Neufeld test, 29.6% (24 of 81) of the invasive isolates in Denmark from 2007 and 2008 were recognised as serotype 6C. In addition, three of eight old isolates originally serotyped as 6A were identified to be serotype 6C. The oldest serotype 6C isolate was from 1962. The serotype 6C isolates belonged to eleven different sequence types (ST) and nine clonal complexes (CC), ST1692 (CC395), ST386 (CC386) and ST481 (CC460) were the predominant types.</p> <p>Conclusions</p> <p>We tested a novel polyclonal antiserum 6 d, as well as modified antiserum 6b*, provided a scheme for the serotyping of <it>S. pneumoniae </it>serogroup 6 using the Neufeld test and compared the serotyping method with PCR based methods. The two types of methods provided the same results. In future, it will, therefore, be possible to test also serotype 6C in accordance to the standard method for serotyping of <it>S. pneumoniae </it>recommended by WHO.</p> <p>Among all invasive isolates from Denmark 2007 and 2008, serotype 6C constituted 29.6% of the original serotype 6A isolates. The serotype 6C isolates were found to be diverse belonging to a number of different STs and CCs of which most have been observed in other countries previously. Serotype 6C is regarded as an "old" serotype being present among <it>S. pneumoniae </it>isolates in Denmark for at least 48 years. The genetic diversity of serotype 6C isolates and their genetic relationship to other serotypes suggested that serotype 6C strains may have arisen from several different independent recombination events involving different parental strains such as serotypes 6A, 6B, 23F and 4.</p

The structure of gauge-invariant ideals of labelled graph C∗C^*-algebras

In this paper, we consider the gauge-invariant ideal structure of a $C^*$-algebra $C^*(E,\mathcal{L},\mathcal{B})$ associated to a set-finite, receiver set-finite and weakly left-resolving labelled space $(E,\mathcal{L},\mathcal{B})$, where $\mathcal{L}$ is a labelling map assigning an alphabet to each edge of the directed graph $E$ with no sinks. Under the assumption that an accommodating set $\mathcal{B}$ is closed under taking relative complement, it is obtained that there is a one to one correspondence between the set of all hereditary saturated subsets of $\mathcal{B}$ and the gauge-invariant ideals of $C^*(E,\mathcal{L},\mathcal{B})$. For this, we introduce a quotient labelled space $(E,\mathcal{L},[\mathcal{B}]_R)$ arising from an equivalence relation $\sim_R$ on $\mathcal{B}$ and show the existence of the $C^*$-algebra $C^*(E,\mathcal{L},[\mathcal{B}]_R)$ generated by a universal representation of $(E,\mathcal{L},[\mathcal{B}]_R)$. Also the gauge-invariant uniqueness theorem for $C^*(E,\mathcal{L},[\mathcal{B}]_R)$ is obtained. For simple labelled graph $C^*$-algebras $C^*(E,\mathcal{L},\bar{\mathcal{E}})$, where $\bar{\mathcal{E}}$ is the smallest accommodating set containing all the generalized vertices, it is observed that if for each vertex $v$ of $E$, a generalized vertex $[v]_l$ is finite for some $l$, then $C^*(E,\mathcal{L},\bar{\mathcal{E}})$ is simple if and only if $(E,\mathcal{L},\bar{\mathcal{E}})$ is strongly cofinal and disagreeable. This is done by examining the merged labelled graph $(F,\mathcal{L}_F)$ of $(E,\mathcal{L})$ and the common properties that $C^*(E,\mathcal{L},\bar{\mathcal{E}})$ and $C^*(F,\mathcal{L},\bar{\mathcal{F}})$ share

Istraživanje lokvi i njihov nestanak na području Parka prirode Žumberak – Samoborsko Gorje, sjeverozapadna Hrvatska

This paper presents the results of surveys of ponds in the Žumberak-Samoborsko gorje Nature Park. The data were collected during 2005 and 164 ponds still present in this area were registered, of at least 342 ponds that were here in the past. The trend in pond loss in this area was calculated, and the opinions of the 54 inhabitants about ponds are analysed.Rad donosi rezultate istraživanja lokvi u Parku prirode Žumberak – Samoborsko gorje. Podaci su prikupljeni tijekom 2005. godine, a zabilježene su 164 lokve, od 342 koliko ih je najmanje postojalo u prošlosti. Izračunat je trend nestajanja lokvi na ovom području te su analizirana mišljenja 54 stanovnika o lokvama

New Gauge Invariant Formulation of the Chern-Simons Gauge Theory: Classical and Quantal Analysis

Recently proposed new gauge invariant formulation of the Chern-Simons gauge theory is considered in detail. This formulation is consistent with the gauge fixed formulation. Furthermore it is found that the canonical (Noether) Poincar\'e generators are not gauge invariant even on the constraints surface and do not satisfy the Poincar\'e algebra contrast to usual case. It is the improved generators, constructed from the symmetric energy-momentum tensor, which are (manifestly) gauge invariant and obey the quantum as well as classical Poincar\'e algebra. The physical states are constructed and it is found in the Schr\"odinger picture that unusual gauge invariant longitudinal mode of the gauge field is crucial for constructing the physical wavefunctional which is genuine to (pure) Chern-Simons theory. In matching to the gauge fixed formulation, we consider three typical gauges, Coulomb, axial and Weyl gauges as explicit examples. Furthermore, recent several confusions about the effect of Dirac's dressing function and the gauge fixings are clarified. The analysis according to old gauge independent formulation a' la Dirac is summarized in an appendix.Comment: No figures, 44 page