28 research outputs found
Effects of CO2 on P-wave attenuation in porous media with micro-cracks: A synthetic modelling study
The presence of CO2 in hydrocarbon reservoirs can cause significant changes in seismic wave properties. In turn these properties can be used to map CO2 saturation in hydrocarbon reservoirs or aquifers â either from natural sources or by injection from the surface. We present the results of a synthetic modelling study of the effects of supercritical CO2 saturation on P-wave attenuation in a medium consisting of four horizontal layers, including a target aquifer. The target aquifer is modelled fully by an effective medium containing pores saturated with brine and/or CO2 and randomly-aligned microcracks at different densities. The other layers are modelled solely by their bulk seismic velocities and densities. We first compute synthetic seismograms for a reference case where the third layer is completely isotropic with no cracks, no pores and no fluid saturation. We then calculate synthetic seismograms for finite crack densities of 0.01, 0.02 and 0.03 at varying degrees of CO2 saturation in the third layer. The results of our analysis indicate that attenuation is sensitive both to CO2 saturation and the crack density. For a given crack density, attenuation increases gradually with decreasing percentage of CO2 saturation and reaches a maximum at around 10% saturation. The induced attenuation increases with crack density and with offset. These observations hold out the potential of using seismic attenuation as an additional diagnostic in the characterisation of rock formations for a variety of applications, including hydrocarbon exploration and production, subsurface storage of CO2 or geothermal energy extractio
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Energetic particle influence on the Earth's atmosphere
This manuscript gives an up-to-date and comprehensive overview of the effects of energetic particle precipitation (EPP) onto the whole atmosphere, from the lower thermosphere/mesosphere through the stratosphere and troposphere, to the surface. The paper summarizes the different sources and energies of particles, principally
galactic cosmic rays (GCRs), solar energetic particles (SEPs) and energetic electron precipitation (EEP). All the proposed mechanisms by which EPP can affect the atmosphere
are discussed, including chemical changes in the upper atmosphere and lower thermosphere, chemistry-dynamics feedbacks, the global electric circuit and cloud formation. The role of energetic particles in Earthâs atmosphere is a multi-disciplinary problem that requires expertise from a range of scientific backgrounds. To assist with this synergy, summary tables are provided, which are intended to evaluate the level of current knowledge of the effects of energetic particles on processes in the entire atmosphere
The forward physics facility at the high-luminosity LHC
High energy collisions at the High-Luminosity Large Hadron Collider (LHC) produce a large number of particles along the beam collision axis, outside of the acceptance of existing LHC experiments. The proposed Forward Physics Facility (FPF), to be located several hundred meters from the ATLAS interaction point and shielded by concrete and rock, will host a suite of experiments to probe standard model (SM) processes and search for physics beyond the standard model (BSM). In this report, we review the status of the civil engineering plans and the experiments to explore the diverse physics signals that can be uniquely probed in the forward region. FPF experiments will be sensitive to a broad range of BSM physics through searches for new particle scattering or decay signatures and deviations from SM expectations in high statistics analyses with TeV neutrinos in this low-background environment. High statistics neutrino detection will also provide valuable data for fundamental topics in perturbative and non-perturbative QCD and in weak interactions. Experiments at the FPF will enable synergies between forward particle production at the LHC and astroparticle physics to be exploited. We report here on these physics topics, on infrastructure, detector, and simulation studies, and on future directions to realize the FPF's physics potential
Mobilization of hematopoietic stem cells: state of the art
Purpose of review: Hematopoietic stem cells (HSCs) normally reside in the bone marrow but can be forced into the blood, a process termed mobilization used clinically to harvest large numbers of HSCs for transplantation. Currently the mobilizing agent of choice is granulocyte colony-stimulating factor; however, not all patients mobilize well. This article reviews recent advances in understanding the molecular mechanisms responsible for the retention of HSCs in the bone marrow, which are perturbed during HSC mobilization, and the clinical application of these findings. Recent findings: The interaction between the chemokine SDF-1/CXCL12 and its receptor CXCR4 is critical to retain HSCs within the bone marrow, leading to the discovery that small synthetic CXCR4 antagonists are potent mobilizing agents that synergize with granulocyte colony-stimulating factor. Separate research has shown that HSC numbers in the bone marrow can be boosted by increasing the number of osteoblasts that support HSCs. Summary: HSC mobilization induced by granulocyte colony-stimulating factor may be enhanced by directly targeting the chemotactic interaction between HSCs and bone marrow stroma with CXCR4 antagonists. When the primary problem is reduced, however, HSC numbers in the bone marrow, due to repeated chemotherapy/radiotherapy treatments, an alternative is to enhance HSC content by enhancing bone formation prior to mobilization