Ultrastructural changes of CA1 subfield of hippocampus of experience stressed rat after acute heat stress

The aim of the present study is to use the transmission electron microscope to characterize the cell death of pyramidal cells from the CA1 subfield of hippocampus after 15 minutes received thermal stress in stress-experienced Sprague Dawley rats. Findings-the rats exposed to acute heat at 42 ºC, the nucleus membrane was destroyed and indeed some of the intracellular went out. In conclusion, acute thermal stress really caused injuries into neurons of the CA1 subfield of hippocampus. Repeated forced swimming stress early in life had enough influence to manipulate heat transmission. Therefore, less alteration are presented by the thermal stress in the experience stressed rat

Increasing The Export Performance of Indonesian MSMEs' Leading Products in The Global Market in Supporting The Economy in 2023

This research activity aims to assist home-based businesses in an effort to improve their product marketability in the global market by improving several important things, including: improving raw materials, building distribution channels, managing sales networks, building their own brands for their products, improving the shape and quality of packaging. with good labeling so that the product can be accepted and able to compete abroad in a wider market. Through this study, researchers conducted interviews, and used research instruments to measure 73 business owners. The goal is that it hampers the process of increasing the export of its products to foreign markets, it turns out that with the results of the interviews it can be seen that there are 12 main variables or factors that must be mastered and/or improved. So that home-based business products can have better performance as desired by overseas buyers or consumers. The testing approach in data processing uses the Tau Kendall W Test combined with the Categorical Test, so that the estimation process can be carried out properly. Through the test approach model and interviews that have been conducted on 73 business actors, it can be seen that the 12 variables or factors stated in this research are the main keywords through improving input, process and product improvement outputs. Product changes can help change the buyer's perception that the products they buy are completely safe and comply with safety, health and material requirements, including parts of environmentally friendly materials

Micro Business Segmentation Using Categorical Test Approach In Supporting Sales Network In East Java Indonesia

The main purpose of this research is to see or position the region in East Java, especially micro-enterprises by segmenting their products. There are five effective areas in East Java which are well-known centers of micro-enterprises, i.e Mojokerto, Pasuruan, Malang, Gresik and Lumajang with their local wisdom products. There are 160 micro business actors in the five regions of East Java. Where their products have the opportunity to be developed into mainstay products in the province of East Java. Based on the results of the Categorical test, an overview of the test results is obtained, i.e: for micro-enterprises in Malang and Gresik they have the same character (dimension 1, i.e: innovation, product attractiveness, product originality, raw materials and environmentally friendly) both management and products so that because they have similarities , the two regions deserve to develop a joint business in a sales network. As for dimension 2 (selling value, market value, quality and market opportunity) micro-enterprises in Pasuruan, Malang and Gresik can form a group together in the sales network in facing market opportunities and increasing sales. Whereas micro-enterprises in Lumajang city (are in a neutral segment (not dimension 1 and not dimension 2), micro-enterprises in Lumajang district may compete with four other cities in fighting for market opportunities, both locally and globally because in the Categorical test the position of micro-enterprises Lumajang is categorized as having a special character and is different from the other four cities, i.e Malang, Gresik, Mojokerto and Pasuruan, so that only micro-enterprises in Lumajang district may not participate in the sales network

PENGARUH KEGIATAN ENTREPRENEURSHIP TERHADAP PENGEMBANGAN DESTINASI WISATA KOTA BATU MALANG

Penelitian ini bertujuan untuk menganalisis pengaruh Entrepreneurship dan Tata kelola usaha terhadap kepemilikan usaha destinasi wisatadi Batu Malang. Populasi dalam  penelitian ini ialah kepemilikan usaha destinasi wisatadi Batu Malang dan sempel yang digunakan dalam penelitian ini sebanyak 45 orang responden. Teknik analisa data menggunakan Regresi Linier Berganda dengan hasil penelitian menunjukan bahwa berdasarkan hasil perhitungan hipotesis secara parsial dengan menggunakan progam analisa statsitik, di peroleh thitung sebesar 2,229 dengan sig 0,031> 0,05 atau dengan taraf signifikan kurang dari 0,05 atau sig sebesar 0,31 yang berarti variabel entrepreneurship secara parsial signifikan berpengaruh terhadap kepemilikan usaha destinasi wisatadi Batu Malang. Berdasarkan dari hasil hipotesis secara parsial dengan menggunakan progam analisa statistik, di peroleh thitung sebesar 2,110 dengan sig 0,041< 0,05 atau dengan taraf signifikan kurang dari 0,05 atau sig. sebesar 0,041 yang berarti variabel tata kelola usaha secara parsial signifikan berpengaruh terhadap kepemilikan usaha destinasi wisatadi Batu Malang

Bali: Tourism Economy The End Of 2021, Will Fly High Again?

Based on the Bali Economic Quarterly Development document for the second quarter of 2021 by BPS, from the beginning of 2020 until now, the Covid-19 pandemic has continued to infect Indonesia. Even the number of new cases affected by this disease is increasing. Based on data from the Covid-19 Handling Task Force, as of June 30, 2021, the number of daily new confirmed cases reached around 21,000. Not only attacking the health sector, but this pandemic has also shattered the joints of the economy. Various government efforts carried out in 2021 have been able to withstand the economic contraction year on year. In the second quarter of 2021, Indonesia's economic growth year on year was recorded at 7.07 percent and was the first positive growth since the second quarter of 2020. In particular, the tourism sector became the sector that experienced the highest growth in the second quarter of 2021. The transportation and accommodation provision business fields, which are the business fields most closely related to the tourism sector, are the two categories that experienced the highest growth, namely by 25.10 percent and 21.58 percent. Among all provinces in Indonesia, Bali can be said to be one of the provinces most affected by the Covid-19 pandemic. Bali's dependence on foreign tourist visits has caused Bali to still slump in the economy. Since March 2020, the arrival of foreign tourists to Bali has continued to decline. The decline even reached almost 100 percent when compared to the same months the previous year

Formulation and evaluation of antimicrobial herbosomal gel from Quercus infectoria extract

Nowadays, the use of herbal medicine is gaining importance for treating many diseases due to their significant effect and lesser side effects as compared to allopathic medicines. Phytosomal herbal formulations or herbosomes are better absorbed and produce better bioavailability than the conventional botanical extracts. Hence, this study is conducted to formulate the herbosomal gel from QI galls ethanolic extract. The QI gall was extracted using ethanol giving the percentage of yield 17%. For the High-Performance Liquid Chromatography analysis, it was revealed that the QI galls extract contains large amount of tannic acid (1794.18 mg/g) and small amount of gallic acid (76.22 mg/g). The formulation consists of 1.0% of Carbopol 940 were found to be the best formulation since it shows good physicochemical properties. pH value was 6.31 while the viscosity was 3482.3144 cps. Formulated gel showed good stability after 21 days of formulation by not showing significance changes in pH value, viscosity and spreadability. Disc diffusion method was used to determine the antimicrobial activity and the results showed the inhibition zone for P. aeruginosa was greater than S. aureus. As conclusion, the QI galls extract formulated herbosomes was showed promising results to be developed as a new antibacterial gel formulation

Second trimester uterine rupture: lesson learned

ntroduction: Uterine rupture is a rare obstetrics catastrophic especially if it occurs during early pregnancy. We experienced three cases of ruptured uterus in the second trimester that first line doctors and obstetrician could learn lessons from. Objectives: To study the presentations and outcome of uterine rupture in the second trimester. Methodology: A retrospective review of uterine rupture in Hospital Tengku Ampuan Afzan from the 1st of April 2010 to the 1st of April 2011. Data obtained from case records, histopathological and autopsy reports. Result: There were 3 cases of uterine rupture. First case, uterine rupture at 15 weeks post sexual intercourse, undiagnosed until postmortem. Second case: ruptured uterus at 24 week diagnosed at laparotomy with the indication of failed medical termination for fetal anomaly. Third case: ruptured uterus at 21 weeks following abdominal massage with initial diagnosis of acute gastroentritis. The final diagnosis was ruptured uterus secondary to placenta percreta, related to medical induction and interstitial pregnancy respectively. Conclusion: Rupture uterus should be considered with or without any risk factors regardless of the gestational age whenever any impression of hemoperitoneum. Intensive surgical method would be needed for accurate diagnosis and immediate management even in early pregnancy is a life saving

Self-healing polyurethane-polypropylene oxide copolymers for the protection of carbon and glass fiber-reinforced composites

Polyurethane-polypropylene oxide block copolymers containing fragments of an adduct capable of self-healing by the Diels-Alder reaction mechanism have been synthesized and studied for the first time. All obtained polyurethane copolymers were characterized by IR spectroscopy. The temperature transitions and thermal stability of copolymer melts were determined by using the methods of differential scanning calorimetry and thermogravimetric analysis. The self-healing effect was confirmed using a thermal cycling procedure on pre-damaged samples of modified polyurethanes and surface morphology studies. The perspective of the work begun on the creation of self-healing protective polyurethane coatings are shown

Robust bifunctional aluminium-salen catalysts for the preparation of cyclic carbonates from carbon dioxide and epoxides

Abstract Two new one-component aluminium-based catalysts for the reaction between epoxides and carbon dioxide have been prepared. The catalysts are composed of aluminium-salen chloride complexes with trialkylammonium groups directly attached to the aromatic rings of the salen ligand. With terminal epoxides, the catalysts induced the formation of cyclic carbonates under mild reaction conditions (25-35 °C; 1-10 bar carbon dioxide pressure). However, with cyclohexene oxide under the same reaction conditions, the same catalysts induced the formation of polycarbonate. The catalysts could be recovered from the reaction mixture and reused. 161

Uterine leiomyoma in the pediatric population: literature review

Uterine fibroids are the most common benign neoplastic tumor of the uterus, occurring in adolescents with a frequency of less than 1%. According to literature data, 87.5% of young patients, as a rule, have a variety of symptoms, the most frequent of which is abnormal uterine bleeding, anemizing the patient, abdominal pain, abdominal enlargement in volume. Diagnosis in adolescent girls may be difficult, due to the rarity, as well as the presence of some limitations in the echographic examination performed, as a rule, by transabdominal access. Methods of treating leiomyomas in women are well known and are widely described in clinical guidelines ranging from surgical to medicinal, however, they are not standardized for the pediatric population. Currently, no more than 25 clinical observations have been described in the literature, which indicates the importance of accumulating clinical data in order to develop an optimal clinical approach aimed at preserving reproductive function in such patients