3,420 research outputs found
Neoadjuvant endocrine therapy for luminal breast cancer treatment: a first-choice alternative in times of crisis such as the COVID-19 pandemic
The epidemiological emergency caused by CoV-2 (COVID-19) has changed priorities in breast cancer management. In those places where the pandemic has had the greatest effect, it is of paramount importance for most patients to be at home, reducing or postponing their attendance at clinics, as well as avoiding surgeries. In this scenario, neoadjuvant endocrine treatment could be an appropriate alternative treatment for hormone receptor positive breast cancer (luminal-like tumours) in order to minimise hospital admissions and to delay elective surgeries. Accordingly, we present a simple protocol that can be applied to most cases of luminal-like breast cancer and is appropriate for the majority of secondary or tertiary medical centres, or even primary car
Random Surfaces that Suppress Single Scattering
We present a method for generating numerically a one-dimensional random
surface, defined by the equation x_3 = \zx, that suppresses single-scattering
processes in the scattering of light from it within a specified range of
scattering angles. Rigorous numerical calculations of the scattering of light
from surfaces generated by this approach show that the single-scattering
contribution to the mean scattered intensity is indeed suppressed within that
range of angles.Comment: 3 pagers (Latex), 3 figure
A tabu search heuristic for the Equitable Coloring Problem
The Equitable Coloring Problem is a variant of the Graph Coloring Problem
where the sizes of two arbitrary color classes differ in at most one unit. This
additional condition, called equity constraints, arises naturally in several
applications. Due to the hardness of the problem, current exact algorithms can
not solve large-sized instances. Such instances must be addressed only via
heuristic methods. In this paper we present a tabu search heuristic for the
Equitable Coloring Problem. This algorithm is an adaptation of the dynamic
TabuCol version of Galinier and Hao. In order to satisfy equity constraints,
new local search criteria are given. Computational experiments are carried out
in order to find the best combination of parameters involved in the dynamic
tenure of the heuristic. Finally, we show the good performance of our heuristic
over known benchmark instances
Design of one-dimensional Lambertian diffusers of light
We describe a method for designing a one-dimensional random surface that acts
as a Lambertian diffuser. The method is tested by means of rigorous computer
simulations and is shown to yield the desired scattering pattern.Comment: 6 pages, 2 figure
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