Multi-decadal Reduction in Glacier Velocities and Mechanisms Driving Deceleration at Polythermal White Glacier, Arctic Canada

Annual and seasonal surface velocities measured continuously from 1960 to 1970 at White Glacier, a 14 km long polythermal valley glacier spanning ~100–1800 m a.s.l., provide the most comprehensive early record of ice dynamics in the Canadian Arctic. Through comparison with differential GPS-derived velocity data spanning 2012–16, we find reductions in mean annual velocity by 31 and 38% at lower elevations (600 and 400 m a.s.l.). These are associated with decreased internal ice deformation due to ice thinning and reduced basal motion likely due to increased hydraulic efficiency in recent years. At higher elevation (~850 m a.s.l.) there is no detectable change in annual velocity and the expected decrease in internal deformation rates due to ice thinning is offset by increased basal motion in both summer and winter, likely attributable to supraglacial melt accessing a still inefficient subglacial drainage system. Decreases in mass flux at lower elevations since the 1960s cannot explain the observed elevation loss of ~20 m, meaning that ice thinning along the glacier trunk is primarily a function of downwasting rather than changing ice dynamics. The current response of the glacier exemplifies steady thinning, velocity slowdown and upstream retreat of the ELA but, because the glacier has an unstable geometry with considerable mass in the 1300–1500 m elevation range, a retreat of the ELA to >1300 plausible within 25–40 years, could trigger runaway wastage

Learning-Focused Leadership and Leadership Support: Meaning and Practice in Urban Systems

Synthesizes three reports on what good education leadership means and how it can best be supported, including the role of the school leader and the transformation of central district offices to focus more on improving instruction. Outlines key practices

Ramond-Ramond Cohomology and O(D,D) T-duality

In the name of supersymmetric double field theory, superstring effective actions can be reformulated into simple forms. They feature a pair of vielbeins corresponding to the same spacetime metric, and hence enjoy double local Lorentz symmetries. In a manifestly covariant manner --with regard to O(D,D) T-duality, diffeomorphism, B-field gauge symmetry and the pair of local Lorentz symmetries-- we incorporate R-R potentials into double field theory. We take them as a single object which is in a bi-fundamental spinorial representation of the double Lorentz groups. We identify cohomological structure relevant to the field strength. A priori, the R-R sector as well as all the fermions are O(D,D) singlet. Yet, gauge fixing the two vielbeins equal to each other modifies the O(D,D) transformation rule to call for a compensating local Lorentz rotation, such that the R-R potential may turn into an O(D,D) spinor and T-duality can flip the chirality exchanging type IIA and IIB supergravities.Comment: 1+37 pages, no figure; Structure reorganized, References added, To appear in JHEP. cf. Gong Show of Strings 2012 (http://wwwth.mpp.mpg.de/members/strings/strings2012/strings_files/program/Talks/Thursday/Gongshow/Lee.pdf

On the Riemann Tensor in Double Field Theory

Double field theory provides T-duality covariant generalized tensors that are natural extensions of the scalar and Ricci curvatures of Riemannian geometry. We search for a similar extension of the Riemann curvature tensor by developing a geometry based on the generalized metric and the dilaton. We find a duality covariant Riemann tensor whose contractions give the Ricci and scalar curvatures, but that is not fully determined in terms of the physical fields. This suggests that \alpha' corrections to the effective action require \alpha' corrections to T-duality transformations and/or generalized diffeomorphisms. Further evidence to this effect is found by an additional computation that shows that there is no T-duality invariant four-derivative object built from the generalized metric and the dilaton that reduces to the square of the Riemann tensor.Comment: 36 pages, v2: minor changes, ref. added, v3: appendix on frame formalism added, version to appear in JHE

A Double Sigma Model for Double Field Theory

We define a sigma model with doubled target space and calculate its background field equations. These coincide with generalised metric equation of motion of double field theory, thus the double field theory is the effective field theory for the sigma model.Comment: 26 pages, v1: 37 pages, v2: references added, v3: updated to match published version - background and detail of calculations substantially condensed, motivation expanded, refs added, results unchange

Massive Type II in Double Field Theory

We provide an extension of the recently constructed double field theory formulation of the low-energy limits of type II strings, in which the RR fields can depend simultaneously on the 10-dimensional space-time coordinates and linearly on the dual winding coordinates. For the special case that only the RR one-form of type IIA carries such a dependence, we obtain the massive deformation of type IIA supergravity due to Romans. For T-dual configurations we obtain a `massive' but non-covariant formulation of type IIB, in which the 10-dimensional diffeomorphism symmetry is deformed by the mass parameter.Comment: 21 page

MTSS1 is a critical epigenetically regulated tumor suppressor in CML

Chronic myeloid leukemia (CML) is driven by malignant stem cells that can persist despite therapy. We have identified Metastasis suppressor 1 (Mtss1/MIM) to be downregulated in hematopoietic stem and progenitor cells from leukemic transgenic SCLtTA/Bcr-Abl mice and in patients with CML at diagnosis, and Mtss1 was restored when patients achieved complete remission. Forced expression of Mtss1 decreased clonogenic capacity and motility of murine myeloid progenitor cells and reduced tumor growth. Viral transduction of Mtss1 into lineage depleted SCLtTA/Bcr-Abl bone marrow cells decreased leukemic cell burden in recipients, and leukemogenesis was reduced upon injection of Mtss1 overexpressing murine myeloid 32D cells. Tyrosine kinase inhibitor (TKI) therapy and reversion of Bcr-Abl expression increased Mtss1 expression but failed to restore it to control levels. CML patient samples revealed higher DNA methylation of specific Mtss1 promoter CpG sites that contain binding sites for Kaiso and Rest transcription factors. In summary, we identified a novel tumor suppressor in CML stem cells that is downregulated by both Bcr-Abl kinase-dependent and -independent mechanisms. Restored Mtss1 expression markedly inhibits primitive leukemic cell biology in vivo, providing a therapeutic rationale for the Bcr-Abl-Mtss1 axis to target TKI resistant CML stem cells in patients

Native-English-Speaking Teachers:Disconnections Between Theory, Research, and Practice

Native-English-speaking teachers (NESTs) have long been in demand for perceived benefits of the skills they bring to the classroom. However, the notion that native speakers provide the best models of the target language and thus make the best teachers of the language has been criticised in the literature. This article reports on the disconnection between academic literature on NESTs and the realities they report. Drawing on data from an investigation into NEST schemes globally, the article suggests that lived classroom experiences of NESTs are complex, They are also often bilingual, experienced, and qualified, and regard local English teachers (LETs) they work with as experts and in control of how English is practised in the classroom. These characteristics contrast with much of the academic literature, which explores the concept of native speakerism, which tends to view NESTs negatively. The article proposes that one reason for the disconnection between theory and practice is the parallel lives of researchers and teachers, whether NESTs or LETs. Thus, each group’s realities and concerns are not always understood by the other. The article suggests that a substantial group of bilingual and bicultural NESTs consider the country where work home, so future theorisations of NESTs and native speakerism should take account of these teachers

Slow change since the Little Ice Age at a far northern glacier with the potential for system reorganization: Thores Glacier, northern Ellesmere Island, Canada

Relatively little is known about the glaciers of northern Ellesmere Island, Canada. Here we describe the first field and remote sensing observations of Thores Glacier, located 50 km inland from the Arctic Ocean. The glacier is slow-moving, with maximum velocities of 26 m a −1 and a maximum observed thickness of 360 ± 4.3 m. There has been little change in terminus position since at least 1959, with a maximum advance of 170 m at the northwest terminus ending on land and retreat up to 130 m at the southeast terminus ending in Thores Lake. There is little evidence for change since the Little Ice Age as bedrock weathering patterns suggest retreat of no more than 20–30 m around most of the glacier margin. The supraglacial drainage network is generally poorly developed, without moulins and with few crevasses, and therefore no evidence of water reaching the glacier bed. This is supported by one-dimensional modelling, which suggests current basal temperatures of −7.0 °C to −12.0 °C along the centerline. Thores Glacier currently dams Thores Lake, which causes drainage to flow to the southeast. However, if the glacier thins or retreats sufficiently, regional drainage will reverse and flow to the north, and Thores Lake would no longer exist