Ultrastructure and Physical Properties of an Adhesive Surface, the Toe Pad Epithelium of the Tree Frog, Litoria caerulea.

Knowledge of both surface structure and physical properties such as stiffness and elasticity are essential to understanding any adhesive system. In this study of an adhesion surface in the tree frog, Litoria caerulea White, a variety of techniques including atomic force microscopy were used to investigate the microstructure and properties of an epithelium that adheres through wet adhesion. Litoria toe pads consist of a hexagonal array of flat-topped epithelial cells, separated by mucus-filled channels. Under an atomic force microscope, this `flat' surface is highly structured at the nanoscale, consisting of a tightly packed array of columnar nanopillars (described as hemidesmosomes by previous authors), 326±84 nm in diameter, each of which possesses a central dimple 8±4 nm in depth. In fixed tissue (transmission electron microscopy), the nanopillars are approximately as tall as they are broad. At the gross anatomical level, larger toe pads may be subdivided into medial and lateral parts by two large grooves. Although the whole toe pad is soft and easily deformable, the epithelium itself has an effective elastic modulus equivalent to silicon rubber (mean Eeff=14.4±20.9 MPa; median Eeff=5.7 MPa), as measured by the atomic force microscope in nanoindentation mode. The functions of these structures are discussed in terms of maximising adhesive and frictional forces by conforming closely to surface irregularities at different length scales and maintaining an extremely thin fluid layer between pad and substrate. The biomimetic implications of these findings are reviewed

Neogene paleoceanography of the eastern equatorial Pacific based on the radiolarian record of IODP drill sites off Costa Rica

The Integrated Ocean Drilling Program (IODP) Expedition 344 drilled cores following a transect across the convergent margin off Costa Rica. Two of the five sites (U1381 and U1414) are the subject of the present study. Major radiolarian faunal breaks and characteristic species groups were defined with the aid of cluster analysis, nodal analysis, and discriminant analysis of principal components. A middle-late Miocene to Pleistocene age (radiolarian zones RN5 to RN16) was determined for the sites, which agrees with the nannofossil zonations and 40Ar/39Ar and tephra layers. Considering the northward movement of the Cocos plate (∼7.3 cm/yr), and a paleolatitude calculator, it is assumed that during the Miocene the two sites were located ∼1000 km to the southwest of their current position, slightly south of the equator. The radiolarian faunas retrieved were thus seemingly formed under the influence of different oceanic currents and sources of nutrients. Changes in the radiolarian assemblages at Site U1414 point at dissimilar environmental settings associated with the colder South Equatorial Current and the warmer Equatorial Countercurrent, as well as to coastal upwelling. These differences are best reflected by changes in the abundance of the morphotype Spongurus spp., with noticeably higher values during the Miocene, than in the Pliocene and the Pleistocene. Because Spongurus spp. is generally associated with cooler waters, these abundance variations (as well as those of several other species) suggest that during the Miocene the area had a stronger influence of colder waters than during younger periods. During the Pliocene and the lowermost Pleistocene, biogenic remains are scarce, presumably due to the terrigenous input, which could have diluted and affected the preservation of pelagic fossils, as well as to the displacement of the site to warmer waters. A typically tropical fauna characterized the Pleistocene, yet with widespread presence of colder water species, most probably indicative of the influence of coastal upwelling processes.Fil: Sandoval, María I.. Universidad de Costa Rica; Costa Rica. Universite de Lausanne; SuizaFil: Boltovskoy, Demetrio. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Ecología, Genética y Evolución de Buenos Aires. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Ecología, Genética y Evolución de Buenos Aires; ArgentinaFil: Baxter, Alan T.. University of New England; Australia. McGill University; CanadáFil: Baumgartner, Peter O.. Universite de Lausanne; Suiz

Self-supervised automated wrapper generation for weblog data extraction

Data extraction from the web is notoriously hard. Of the types of resources available on the web, weblogs are becoming increasingly important due to the continued growth of the blogosphere, but remain poorly explored. Past approaches to data extraction from weblogs have often involved manual intervention and suffer from low scalability. This paper proposes a fully automated information extraction methodology based on the use of web feeds and processing of HTML. The approach includes a model for generating a wrapper that exploits web feeds for deriving a set of extraction rules automatically. Instead of performing a pairwise comparison between posts, the model matches the values of the web feeds against their corresponding HTML elements retrieved from multiple weblog posts. It adopts a probabilistic approach for deriving a set of rules and automating the process of wrapper generation. An evaluation of the model is conducted on a dataset of 2,393 posts and the results (92% accuracy) show that the proposed technique enables robust extraction of weblog properties and can be applied across the blogosphere for applications such as improved information retrieval and more robust web preservation initiatives

Amphibian Diversity and Nestedness in a Dynamic Floodplain River (Tagliamento, NE-Italy)

Amphibian distribution and assemblage structure were investigated along the last morphologically intact river corridor in Central Europe (Tagliamento). Thirteen taxa were identified with Rana latastei and Bufo bufo being the predominant species. In the main study reach, a 2km2 dynamic island-braided floodplain in the middle section of the river, 130 water bodies were delineated that were situated either in the active floodplain (82 sites) or in the adjacent riparian forest (48 sites). Results demonstrated that the active floodplain increased appreciably the available habitat for amphibians, despite frequent disturbances by floods or droughts. Amphibian richness within a given habitat was significantly correlated with distance from vegetated islands, fish density, and water temperature. In the active floodplain, species distribution was highly predictable, exhibiting nearly perfect nestedness, suggesting that selective colonisation and extinction processes predominated. The degree of nestedness was much higher than in the adjacent riparian forest or in regulated floodplains in Central Europe. Results clearly emphasise that amphibians can exploit the entire hydrodynamic gradient, except the main channel. In the active floodplain, vegetated islands and large woody debris are important, directly and indirectly, in maintaining both habitat and amphibian diversity and density in this gravel-bed rive

Endovascular Treatment of Renal Artery Bifurcation Stenoses with Branched Balloon Angioplasty

An 85-year-old man with left sided single kidney presented with end-stage renal failure after an acute intestinal bleeding. A complex bifurcational stenoses distally to a 6 months previously implanted ostial stent in the left renal artery was found on duplex imaging and angiogram. These two de-novo stenoses in the distal main renal artery and the proximal segment of the lower branch were simultaneously treated with a ultra-low profile, monorail bifurcation balloon catheter system (Avion Bifurcation RX2™, Invatec, Italy) that consists of a main vessel balloon (20/3.5mm) and a side vessel balloon (20/2.75mm). One day and three months postinterventionally, duplex ultrasound demonstrated no recurrent stenoses. Bifurcation balloon catheter systems for complex renal artery stenosis are discussed

Die endovaskuläre Ausbildung für Gefäßchirurgen an der Universitätsklinik Bern

Zusammenfassung: Die technische Entwicklung im Bereich von Katheterinterventionen hat auch zunehmenden Einfluss auf das Tätigkeitsfeld der Gefäßchirurgen. Im Operationssaal werden häufiger additive Katheterinterventionen oder Kombinationsverfahren, auch Hybrideingriffe genannt, durchgeführt. Dies setzt zwingend kathetertechnische Fertigkeiten voraus. Deshalb werden an der Klinik und Poliklinik für Herz- und Gefäßchirurgie in Bern in Zusammenarbeit mit interventionell tätigen Angiologen und Radiologen die Gefäßchirurgen in kathetertechnischen Interventionen trainiert. Katheterinterventionen zwingen dazu, die technische Ausrüstung des Operationssaals laufend anzupassen und die Schulung des Assistenzpersonals zu förder

Investor protection through model case procedures – implementing collective goals and individual rights under the 2012 Amendment of the German Capital Markets Model Case Act (KapMuG)

The German Capital Markets Model Case Act (KapMuG) and its amendment of 2012 highlight some fundamentals of collective redress in civil law countries at the example of model case procedures in the field of investor protection. That is why a survey of the ongoing activities of the European Union in the area of collective redress and of its repercussions on the member state level forms a suitable basis for the following analysis of the 2012 amendment of the KapMuG. It clearly brings into focus a shift from sector-specific regulation with an emphasis on the cross-border aspect of protecting consumers towards a “coherent approach” strengthening the enforcement of EU law. As a result, regulatory policy and collective redress are two sides of the same coin today. With respect to the KapMuG such a development brings about some tension between its aim to aggregate small individual claims as efficiently as possible and the dominant role of individual procedural rights in German civil procedure. This conflict can be illustrated by some specific rules of the KapMuG: its scope of application, the three-tier procedure of a model case procedure, the newly introduced notification of claims and the new opt-out settlement under the amended §§ 17-19