2,778 research outputs found

    Complex project scheduling

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    Student Modeling Based on Fine-Grained Programming Process Snapshots

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    ICER '17 Proceedings of the 2017 ACM Conference on International Computing Education Research. New York, NY, USA : ACM, 2017 ISBN: 978-1-4503-4968-0I am studying the use of fine-grained programming process data for student modeling. The initial plan is to construct different types of program state representations such as Abstract Syntax Trees (ASTs) from the data. These program state representations could be used for both automatically inferring knowledge components that the students are trying to learn as well as for modeling students' knowledge on those specific components.Peer reviewe

    Permeability characteristics of human endothelial monolayers seeded on different extracellular matrix proteins.

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    OBJECTIVE: To investigate whether endothelial monolayer permeability changes induced by inflammatory mediators are affected by the extracellular matrix protein used for cell seeding. METHODS: Human umbilical venular endothelial cells (HUVEC) were grown to confluent monolayers on membranes coated with either collagen, fibronectin or gelatin. The permeability to albumin and dextran was then assessed, both under normal conditions and after treatment with tumor necrosis factor-alpha (TNF-alpha) and bacterial lipopolysaccharide (LPS). RESULTS: With any of the three protein coatings, tight junctions were formed all over the monolayers. The permeability of the coated membranes to albumin and dextran was reduced strongly by confluent monolayers; the relative reduction was similar for the three matrix proteins used. Pre-incubation of the monolayers with either TNF-alpha or LPS increased permeability dose dependently. However, the relative increase due to either treatment was independent of the protein used for membrane coating. CONCLUSION: The extracellular matrix protein used for initial seeding of endothelial cultures plays a minor role in determining the permeability changes induced in HUVEC monolayers by inflammatory mediators

    Methodiek schoolverlatersinformatiesysteem 1996

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    On the derivation of SPH schemes for shocks through inhomogeneous media

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    Smoothed Particle Hydrodynamics (SPH) is typically used for the simulation of shock propagation through solid media, commonly observed during hypervelocity impacts. Although schemes for impacts into monolithic structures have been studied using SPH, problems occur when multimaterial structures are considered. This study begins from a variational framework and builds schemes for multiphase compressible problems, coming from different density estimates. Algorithmic details are discussed and results are compared upon three one-dimensional Riemann problems of known behavior

    Impact of Atmospheric Rivers on Future Poleward Moisture Transport and Arctic Climate in EC-Earth2

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    Alongside mean increases in poleward moisture transport (PMT) to the Arctic, most climate models also project a linear increase in the interannual variability (IAV) with future warming. It is still uncertain to what extent atmospheric rivers (ARs) contribute to the projected IAV increase of PMT. We analyzed large-ensemble climate simulations to (a) explore the link between PMT and ARs in the present-day (PD) and in two warmer climates (+2 and +3°C compared to pre-industrial global mean temperature), (b) assess the dynamic contribution to changes in future ARs, and (c) analyze the effect of ARs on Arctic climate on interannual timescales. We find that the share of AR-related PMT (ARPMT) to PMT increases from 42% in the PD to 53% in the +3°C climate. Our results show that the mean increases in AR-frequency and intensity are mainly caused by higher atmospheric moisture levels, while dynamic variability regulates regional ARs on an interannual basis. Notably, the amount of ARs reaching the Arctic in any given region and season strongly depends on the regional jet stream position and speed southwest of this region. This suggests that future changes in dynamics may significantly amplify or dampen the regionally consistent moisture-induced increase in ARs in a warmer climate. Our results further support previous findings that positive ARPMT anomalies are profoundly linked to increased surface air temperature and precipitation, especially in the colder seasons, and have a predominantly negative effect on sea ice.</p

    Does implicit memory during anaesthesia persist in children?

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    Background Recent studies suggest that implicit memory (especially perceptual implicit memory) persists during adequate general anaesthesia in adults. Studies in children, however, have failed to demonstrate implicit memory during general anaesthesia, possibly because of differences in methodological design. We therefore designed a prospective study with the aim of evaluating implicit memory in children undergoing general anaesthesia, using a perceptual memory test based on the mere exposure effect, previously tested in a control group. Methods Twelve infrequent neutral words were played 12 times in a random sequence via headphones to 36 children aged 8-12 yr during elective or emergency surgery. The children were not premedicated, and general anaesthesia was maintained with isoflurane. The word presentation started immediately after the surgical incision. Within 36 h after the stimulus presentation, the memory was assessed by using a forced-choice preference judgement task. Time constraint and word deterioration with a low-pass filter were used to prevent the subjects from utilizing intentional retrieval. The implicit memory score was obtained by calculating the proportion of target words preferred, which was compared with the chance level (0.5). Results The percentage of correct responses given by the children was comparable with the chance level. The memory score was mean (sd) 0.48 (0.16) (95% CI 0.43-0.53). Conclusions The use of a perceptual implicit memory test based on the mere exposure procedure in children failed to reveal any evidence of implicit memory under general anaesthesi

    A latent trait look at pretest-posttest validation of criterion-referenced test items

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    Since Cox and Vargas (1966) introduced their pretest-posttest validity index for criterion-referenced test items, a great number of additions and modifications have followed. All are based on the idea of gain scoring; that is, they are computed from the differences between proportions of pretest and posttest item responses. Although the method is simple and generally considered as the prototype of criterion-referenced item analysis, it has many and serious disadvantages. Some of these go back to the fact that it leads to indices based on a dual test administration- and population-dependent item p values. Others have to do with the global information about the discriminating power that these indices provide, the implicit weighting they suppose, and the meaningless maximization of posttest scores they lead to. Analyzing the pretest-posttest method from a latent trait point of view, it is proposed to replace indices like Cox and Vargas’ Dpp by an evaluation of the item information function for the mastery score. An empirical study was conducted to compare the differences in item selection between both methods
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