Annular elastolytic giant cell granuloma: a "visible" diagnosis

Annular elastolytic giant cell granuloma (AEGCG) is a rare granulomatous skin disease of undetermined cause, characterized by annular plaques with raised erythematous borders in sun-exposed skin. The typical histologic features are dermal infiltration by multinucleated giant cells, elastin degeneration, and elastophagocytosis. The authors describe a clinical case of AEGCG, which exhibited an excellent response to hydroxycloroquine.info:eu-repo/semantics/publishedVersio

Adult blaschkolinear acquired inflammatory skin eruption (BLAISE) with simultaneous features of lichen striatus and blaschkitis

Blaschkitis and lichen striatus are generally distinguished in the literature by the age of onset, lesion distribution, and histopathology. However, there is currently no clear consensus among authors about whether to consider blaschkitis and lichen striatus different clinical entities or a spectrum ofthe same disease. We present a case of adult BLAISE with features of both lichen striatus and blaschkitis, which seems to support the theory that these clinical entities may in fact represent a spectrum of the same pathological process.info:eu-repo/semantics/publishedVersio

Infantile bullous pemphigoid with "string of pearls sign"

Bullous pemphigoid (BP) is an immune mediated bullous disease that is manifested by urticarial plaques with superimposed subepidermal blisters and significant pruritus. It is generally found in the elderly, but is rare in the pediatric population. A 5-month-old girl previously diagnosed with hand-foot-mouth disease was examined in our dermatology department owing to vesicles and bullae, initially located to the hands and feet, which progressed with new lesions. Tense vesicles and bullae distributed in an annular string of pearls pattern on the abdomen and facial and cervical regions were noted. Histologic and immunologic findings were consistent with the diagnosis of infantile BP. Disease control was obtained with oral prednisolone and dapsone; the patient was still in clinical remission 6 months after treatment cessation. The differential diagnosis of the clinical presentation of the lesions in our patient is of note, given that this blistering pattern is frequently reported in association with linear IgA bullous dermatosis.info:eu-repo/semantics/publishedVersio

Walks In Nature As Exercise Of Self- Knowledge: Leading To Authentic Happiness.

The concern for the environment begun to emerge in a more intriguing way in 1960 ́s, and since then a long journey of reflections about the origin and mitigation of atrocities committed by the human being has triggered ecological movements, laws and higher education graduations. However, the root of all environmental barbarism lies on the human being crises and his distorted, corrupted values. Nowadays, the confront with that crises led to an increasing questioning about the human essence, whether individually or collectively or in the field of science. The present qualitative study aimed to evaluate the effect of the natural world experience on the participants of a walk known as Eco or Walking Coaching performed with so-called Animistic Activities – AA (perception exercises, play games and group experiences, mindfulness, among others). The results pointed out that these experiences are an excellent stage for reflections that lead to self-knowledge and, consequently, the revision of values and attitudes that may promote a sustainably happy life