1,484 research outputs found

    Learning from interactions with prisoners

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    Self-interest And Public Interest: The Motivations Of Political Actors

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    Self-Interest and Public Interest in Western Politics showed that the public, politicians, and bureaucrats are often public spirited. But this does not invalidate public-choice theory. Public-choice theory is an ideal type, not a claim that self-interest explains all political behavior. Instead, public-choice theory is useful in creating rules and institutions that guard against the worst case, which would be universal self-interestedness in politics. In contrast, the public-interest hypothesis is neither a comprehensive explanation of political behavior nor a sound basis for institutional design

    Developments in cell biology for quantitative immunoelectron microscopy based on thin sections: a review

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    Quantitative immunoelectron microscopy uses ultrathin sections and gold particle labelling to determine distributions of molecules across cell compartments. Here, we review a portfolio of new methods for comparing labelling distributions between different compartments in one study group (method 1) and between the same compartments in two or more groups (method 2). Specimen samples are selected unbiasedly and then observed and expected distributions of gold particles are estimated and compared by appropriate statistical procedures. The methods can be used to analyse gold label distributed between volume-occupying (organelle) and surface-occupying (membrane) compartments, but in method 1, membranes must be treated as organelles. With method 1, gold counts are combined with stereological estimators of compartment size to determine labelling density (LD). For volume-occupiers, LD can be expressed simply as golds per test point and, for surface-occupiers, as golds per test line intersection. Expected distributions are generated by randomly assigning gold particles to compartments and expressing observed/expected counts as a relative labelling index (RLI). Preferentially-labelled compartments are identified from their RLI values and by Chi-squared analysis of observed and expected distributions. For method 2, the raw gold particle counts distributed between compartments are simply compared across groups by contingency table and Chi-squared analysis. This identifies the main compartments responsible for the differences between group distributions. Finally, we discuss labelling efficiency (the number of gold particles per target molecule) and describe how it can be estimated for volume- or surface-occupiers by combining stereological data with biochemical determinations

    VUV photon induced fluorescence study of SF5CF3

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    The interaction of SF5_5CF3_3 with vacuum-UV radiation has been investigated by photon induced fluorescence spectroscopy. Total fluorescence yield and dispersed fluorescence spectra of SF5_5CF3_3 were recorded in the 200-1000 nm fluorescence window. In all cases, the fluorescence spectra resemble those of CF3_3X (X=H, F, Cl, and Br) molecules. At photon energies below 20 eV, the emission is attributed to the excited CF3_3 and CF2_2 fragments. The threshold for the CF3_3 emission is 10.2 ± 0.2 eV, giving an upper-limit estimate for the SF5_5-CF3_3 bond dissociation energy of 3.9 ± 0.3 eV. The excitation functions of the CF3 and CF2 emissions were measured in the photon energy range 13.6 – 27.0 eV. The resonant structures observed in SF5_5CF3_3 are attributed to electronic transitions from valence to Rydberg orbitals, following similar assignments in CF3_3X molecules. The photoabsorption spectrum of SF5_5CF3_3 shows features at the same energies, indicating a strong contribution from Rydberg excitations

    Inclusive growth in English cities: mainstreamed or sidelined?

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    <p>The concept of inclusive growth is increasingly presented as offering prospects for more equitable social outcomes. However, inclusive growth is subject to a variety of interpretations and lacks definitional clarity. In England, via devolution, cities are taking on new powers for policy domains that can influence inclusive growth outcomes. This opens up opportunities for innovation to address central issues of low pay and poverty. This paper examines the extent to which inclusive growth concerns form a central or peripheral aspect in this new devolution through the content analysis of devolution agreements. It concludes that inclusive growth concerns appear to be largely sidelined.</p

    Congressional campaign effects on candidate recognition and evaluation

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    To date, most congressional scholars have relied upon a standard model of American electoral behavior developed in the presidential setting. This research extends our knowledge of Congressmen's incumbency advantages and their sources. Candidate preference is viewed as a function of the relative recognition and evaluation of incumbents and their challengers, as well as of Democrats and Republicans. In the recognition model, contact with voters and media effects are quite important, but there is no direct role for party identification. Evaluation is a function of personal contact and party identification, and media variables are insignificant. Relative recognition, relative evaluation, and party identification are three important predictors of candidate preference, and incumbency itself adds little beyond what is contained in incumbent recognition and evaluation advantages.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/45489/1/11109_2004_Article_BF00989756.pd

    Reliability of 1-repetition maximum estimation for upper and lower body muscular strength measurement in untrained middle aged type 2 diabetic patients

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    Purpose: The 1-repetition maximum (1-RM) test is the gold standard test for evaluating maximal dynamic strength of groups of muscles. However, safety of actual 1-RM testing is questionable in clinical situations such as type 2 diabetes (T2D), where an estimated 1-RM test is preferred. It is unclear if acceptable test retest reliability exists for the estimated 1-RM test in middle aged T2D patients. This study examined the reliability of the estimated 1-RM strength test in untrained middle aged T2D subjects.Methods: Twenty five untrained diabetic males (n=19) and females (n=6) aged 40.7+0.4 years participated in the study. Participants undertook the first estimated 1-RM test for five exercises namely supine bench press, leg press, lateral pull, leg extension and seated biceps curls. A familiarisation session was provided three to five days before the first test. 1-RM was estimated for all participants by Brzycki 1-RM prediction equation. Another identical 1-RM estimation procedure occurred one week after first test. Intraclass correlation coefficients (ICC), paired t-test, standard error of measurement (SEM), Bland-Altman plots, and estimation of 95% CI were used to assess reliability.Results: Test-retest reliability was excellent (ICC2,1=0.98-0.99) for all measurements with the highest for leg extension (ICC2,1=0.99). The SEM was lowest for lateral pull and leg extension exercises. Paired t-tests showed non-significant differences between the means of 2 sessions across three of five exercises.Conclusions: The study findings suggest that estimation of 1-RM is reliable for upper and lower body muscular strength measurement in untrained middle aged T2D patients.https://doi.org/10.5812/asjsm.345493pubpub

    The effect of carbohydrate ingestion on the motor skill proficiency of soccer players

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    This study examined the effects of ingesting a glucose-polymer (GP) solution on the motor skill proficiencies of association football (soccer) players from two teams playing during two matches in a cool environment. Fifteen minutes before each match and at halftime, players from both teams ingested 5 ml/kg of either placebo or a 6.9% GP solution. GP ingestion did not improve tackling, heading, dribbling, or shooting ability. On the contrary, the mean of successful tackles was lower with GP ingestion than with placebo. The success rate for heading, dribbling, and shooting also tended to be lower in the GP than in the placebo condition. In contrast, success in passing and ball control was similar in the two conditions. Improvements in passing and ball control may have been related to a decrease in the intensity of play in the second half of the game. These data indicate that there are no measurable benefits of GP ingestion for the motor skill proficiencies of soccer players during games played in a cool environment.IS
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