Using evidence to inform health policy: case study

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Examining Body-Focused Self-Improvement and Self-Evaluation Social Comparisons on Exercise in Young Adult Women Using Ecological Momentary Assessment

Exercise is highly recommended by health professionals due to its numerous health benefits, yet little is known about the social factors that influence people’s motivation to exercise each day. Studies on social comparisons reveal that college women frequently evaluate their weight and shape compared to those around them through upward body-focused comparisons (i.e., comparing themselves to someone they perceive to be thinner or in better physical shape). Research suggests these comparisons can be driven by two different motivations, self-evaluation and self-improvement. However, the occurrence of these two different types of motivations in everyday life and how they may be associated with different levels of body dissatisfaction and exercise behaviors have yet to be examined in an ecologically valid study. The purpose of this study was to examine whether the way in which women seek and internalize daily upward body-focused social comparisons, in a self-evaluation or a self-improvement manner, is associated with different levels of body dissatisfaction, exercise intentions, and behaviors. Undergraduate college women (N = 74, Mage = 20.4 years) completed ecological momentary assessment measures on the frequency and nature of their social comparisons, their thoughts of exercising, and body dissatisfaction five times per day for seven consecutive days. Intentions to exercise the next day were gathered each night and their exercise behavior was collected continuously with a Fitbit accelerometer. Multilevel analyses revealed that comparisons high in self-evaluation and self-improvement were significantly associated with greater momentary thoughts of exercising (ps.05). However, person-level differences in baseline measures of body dissatisfaction, appearance comparison tendency, and exercise behaviors used as moderators revealed differences between these motivations as well as their associations with body dissatisfaction and exercise behaviors. This was the first study to examine motivations to engage in naturally occurring upward body-focused comparisons. Theoretical and clinical implications associated with self-improvement motivation findings and future directions for research are discussed

Body Dissatisfaction and Disordered Eating Among College Women’s Social Networks: An Investigation of Perceived Changes Following a Dissonance-Based Body Image Intervention

Body dissatisfaction is associated with numerous health consequences and is pervasive among college women. Effective interventions exist that reduce body dissatisfaction in college women by helping them resist sociocultural pressures to conform to the appearance ideal, such as the Body Project. Yet research is limited on whether social and behavioral processes help participants reduce their engagement in sociocultural appearance-ideal messages and contribute to the intervention’s effectiveness. The primary purpose of the present study was to examine these social and behavioral processes, including the changes in college women’s social networks associated with their participation in the Body Project. Undergraduate and graduate students participated in the two session, peer-led version of the Body Project and completed measures at five timepoints (Baseline 1, Baseline 2, Post-intervention, 1-month Follow-up, 3-month Follow-up). The measures assessed constructs examined previously in Body Project research in addition to body dissatisfaction maintenance behaviors (appearance comparison tendency, body checking, and negative body talk) and participants’ perceived social networks’ body dissatisfaction and related behaviors. Seventy-nine completed Baseline 1, of which 39 completed at least one Body Project session and 31 completed the full two-session intervention. Because of the coronavirus pandemic, Body Project groups were stopped indefinitely and 22 who completed Baseline 1 were unable to attend their pre-scheduled group. Latent growth models with three piecewise slopes (assessment effects, intervention effects, and maintenance effects) were used to examine changes in these measures beyond the effects of time. Significant intervention effects were found for the previously measured constructs and the body dissatisfaction maintenance behaviors examined. One marginally significant change in participants’ social networks was found; the friends participants removed from their social networks engaged in more disordered eating than the friends they added at 1-month follow-up. Despite this limited evidence for social network change, the study revealed several ways in which social networks may perpetuate body dissatisfaction and related behaviors. This was one of the first studies to examine these social and behavioral processes within the Body Project and assess these constructs in women’s social networks. Findings suggest that additional processes, including reductions in body dissatisfaction maintenance behaviors and the facilitation of perceived group similarity and closeness contribute to the intervention’s effectiveness and should be explored further in future research and considered in the development of cost-effective intervention modifications

Virtue and austerity

Virtue ethics is often proposed as a third way in health-care ethics, that while consequentialism and deontology focus on action guidelines, virtue focuses on character; all three aim to help agents discern morally right action although virtue seems to have least to contribute to political issues, such as austerity. I claim: (1) This is a bad way to characterize virtue ethics. The 20th century renaissance of virtue ethics was first proposed as a response to the difficulty of making sense of ‘moral rightness’ outside a religious context. For Aristotle the right action is that which is practically best; that means best for the agent in order to live a flourishing life.There are no moral considerations besides this. (2) Properly characterized, virtue ethics can contribute to discussion of austerity. A criticism of virtue ethics is that fixed characteristics seem a bad idea in ever-changing environments; perhaps we should be generous in prosperity, selfish in austerity. Furthermore, empirical evidence suggests that people indeed do change with their environment. However, I argue that virtues concern fixed values not fixed behaviour; the values underlying virtue allow for different behaviour in different circumstances: in austerity, virtues still give the agent the best chance of flourishing. Two questions arise. (a) In austere environments might not injustice help an individual flourish by, say, obtaining material goods? No, because unjust acts undermine the type of society the agent needs for flourishing. (b) What good is virtue to those lacking the other means to flourish? The notion of degrees of flourishing shows that most people would benefit somewhat from virtue. However, in extreme circumstances virtue might harm rather than benefit the agent: such circumstances are to be avoided; virtue ethics thus has a political agenda to enable flourishing. This requires justice, a fortiori when in austerity

Managerial Work in a Practice-Embodying Institution - The role of calling, the virtue of constancy

What can be learned from a small scale study of managerial work in a highly marginal and under-researched working community? This paper uses the ‘goods-virtues-practices-institutions’ framework to examine the managerial work of owner-directors of traditional circuses. Inspired by MacIntyre’s arguments for the necessity of a narrative understanding of the virtues, interviews explored how British and Irish circus directors accounted for their working lives. A purposive sample was used to select subjects who had owned and managed traditional touring circuses for at least 15 years, a period in which the economic and reputational fortunes of traditional circuses have suffered badly. This sample enabled the research to examine the self-understanding of people who had, at least on the face of it, exhibited the virtue of constancy. The research contributes to our understanding of the role of the virtues in organizations by presenting evidence of an intimate relationship between the virtue of constancy and a ‘calling’ work orientation. This enhances our understanding of the virtues that are required if management is exercised as a domain-related practice

Task-irrelevant auditory metre shapes visuomotor sequential learning

The ability to learn and reproduce sequences is fundamental to every-day life, and deficits in sequential learning are associated with developmental disorders such as specific language impairment. Individual differences in sequential learning are usually investigated using the serial reaction time task (SRTT), wherein a participant responds to a series of regularly timed, seemingly random visual cues that in fact follow a repeating deterministic structure. Although manipulating inter-cue interval timing has been shown to adversely affect sequential learning, the role of metre (the patterning of salience across time) remains unexplored within the regularly timed, visual SRTT. The current experiment consists of an SRTT adapted to include task-irrelevant auditory rhythms conferring a sense of metre. We predicted that (1) participants’ (n = 41) reaction times would reflect the auditory metric structure; (2) that disrupting the correspondence between the learned visual sequence and auditory metre would impede performance; and (3) that individual differences in sensitivity to rhythm would predict the magnitude of these effects. Altering the relationship via a phase shift between the trained visual sequence and auditory metre slowed reaction times. Sensitivity to rhythm was predictive of reaction times over all. In an exploratory analysis, we, moreover, found that approximately half of participants made systematically different responses to visual cues on the basis of the cues’ position within the auditory metre. We demonstrate the influence of auditory temporal structures on visuomotor sequential learning in a widely used task where metre and timing are rarely considered. The current results indicate sensitivity to metre as a possible latent factor underpinning individual differences in SRTT performance

On Recurrent Reachability for Continuous Linear Dynamical Systems

The continuous evolution of a wide variety of systems, including continuous-time Markov chains and linear hybrid automata, can be described in terms of linear differential equations. In this paper we study the decision problem of whether the solution $\boldsymbol{x}(t)$ of a system of linear differential equations $d\boldsymbol{x}/dt=A\boldsymbol{x}$ reaches a target halfspace infinitely often. This recurrent reachability problem can equivalently be formulated as the following Infinite Zeros Problem: does a real-valued function $f:\mathbb{R}_{\geq 0}\rightarrow\mathbb{R}$ satisfying a given linear differential equation have infinitely many zeros? Our main decidability result is that if the differential equation has order at most $7$, then the Infinite Zeros Problem is decidable. On the other hand, we show that a decision procedure for the Infinite Zeros Problem at order $9$ (and above) would entail a major breakthrough in Diophantine Approximation, specifically an algorithm for computing the Lagrange constants of arbitrary real algebraic numbers to arbitrary precision.Comment: Full version of paper at LICS'1

Murdoch and the End of Ideology

Iris Murdoch had a lifelong interest in politics and she reflected upon the nature of ideology throughout her career. What she had to say on the subject developed during her career and relates to general academic discussions on the nature of ideology. At the outset of her career she was a committed socialist. She recognised that political ideology was in retreat after the Second World War but sought to contribute to socialist ideology. Later in her career she became sceptical of radical utopian ideologies, including socialism and developed a theory of politics that prioritised safeguarding individual liberty and security. However, she imagined that political thought would continue to develop and offer new possibilities and so she did not call for the end of ideology but continued to value political ideas

Electron mobility in surface- and buried- channel flatband In_0.53Ga_0.47As MOSFETs with ALD Al₂O₃ gate dielectric.

In this paper, we investigate the scaling potential of flatband III-V MOSFETs by comparing the mobility of surface and buried In<sub>0.53</sub>Ga<sub>0.47</sub>As channel devices employing an Atomic Layer Deposited (ALD) Al<sub>2</sub>O<sub>3</sub> gate dielectric and a delta-doped InGaAs/InAlAs/InP heterostructure. Peak electron mobilities of 4300 cm<sup>2</sup>/V·s and 6600 cm<sup>2</sup>/V·s at a carrier density of 3×1012 cm<sup>-2</sup> for the surface and buried channel structures respectively were determined. In contrast to similarly scaled inversion-channel devices, we find that mobility in surface channel flatband structures does not drop rapidly with electron density, but rather high mobility is maintained up to carrier concentrations around 4x10<sup>12</sup> cm<sup>-2</sup> before slowly dropping to around 2000 cm<sup>2</sup>/V·s at 1x10M<sup>13</sup> cm<sup>-2</sup>. We believe these to be world leading metrics for this material system and an important development in informing the III-V MOSFET device architecture selection process for future low power, highly scaled CM

Pathfinder cells provide a novel therapeutic intervention for acute kidney injury

Pathfinder cells (PCs) are a novel class of adult-derived cells that facilitate functional repair of host tissue. We used rat PCs to demonstrate that they enable the functional mitigation of ischemia reperfusion (I/R) injury in a mouse model of renal damage. Female C57BL/6 mice were subjected to 30 min of renal ischemia and treated with intravenous (i.v.) injection of saline (control) or male rat pancreas-derived PCs in blinded experimentation. Kidney function was assessed 14 days after treatment by measuring serum creatinine (SC) levels. Kidney tissue was assessed by immunohistochemistry (IHC) for markers of cellular damage, proliferation, and senescence (TUNEL, Ki67, p16ink4a, p21). Fluorescence in situ hybridization (FISH) was performed to determine the presence of any rat (i.e., pathfinder) cells in the mouse tissue. PC-treated animals demonstrated superior renal function at day 14 post-I/R, in comparison to saline-treated controls, as measured by SC levels (0.13 mg/dL vs. 0.23 mg/dL, p<0.001). PC-treated kidney tissue expressed significantly lower levels of p16ink4a in comparison to the control group (p=0.009). FISH analysis demonstrated that the overwhelming majority of repaired kidney tissue was mouse in origin. Rat PCs were only detected at a frequency of 0.02%. These data confirm that PCs have the ability to mitigate functional damage to kidney tissue following I/R injury. Kidneys of PC-treated animals showed evidence of improved function and reduced expression of damage markers. The PCs appear to act in a paracrine fashion, stimulating the host tissue to recover functionally, rather than by differentiating into renal cells. This study demonstrates that pancreatic-derived PCs from the adult rat can enable functional repair of renal damage in mice. It validates the use of PCs to regenerate damaged tissues and also offers a novel therapeutic intervention for repair of solid organ damage in situ