895 research outputs found
Effectiveness of a temperature control system in home induction hobs to reduce acrylamide formation during pan frying
The trajectories of EAEC countries development: Numerical analysis of competitive strategies in investments
This paper discusses comparative analysis of trajectories in the development of participating countries of the Eurasian Economic Union (EAEC) in a two-dimensional phase space. The coordinates in the space is represented by the value of a dynamic variable that is a key indicator of the country's development, and the rate of its relative growth. This allows for construction of a ternary classification diagram describing competitive behavior strategies of countries in question. The comparative analysis was run for two primary factors: the size of investment in the main capital and R&D spendings. The authors carried out analysis and identification of competitive strategies for the behavior of the EAEC countries, as well as he proposed conclusions and recommendations on improving the policy of economic development. © 2017 Author(s)
Structural insights into the similar modes of Nrf2 transcription factor recognition by the cytoplasmic repressor Keap1
The structure of mouse Keap1-DC complexed with the DLG motif peptide of Nrf2 transcription factor was determined at 1.9 Å resolution. The structure showed that the peptide binds to Keap1-DC at the bottom region of the β-propeller domain
ПРОГНОЗУВАННЯ КЛІНІЧНОГО ПЕРЕБІГУ ВИРАЗКОВОЇ ХВОРОБИ ШЛУНКА
The authors made morphological and functional researches of the stomach on 76 patients to determine the prognosis of stomsch ulcer’ clinical manifestation, complications’ prevention and a choice of an adequate method of treatment. Complex clinical research and studying of motor, evacuation and secretory functions and the degrees of stomach pollution by Helicobacter pylori gave an opportunity to determine the risk groups, to predict the clinical manifestation of disease, to develop indications for conservative treatment, to determine its amount and to prove the necessity of surgical intervention in every particular case. Such approach to the treatment allows to improve considerably results of patients’ cure from stomach ulcer and to reduce terms of rehabilitation of patients from 45 to 30 days.Для визначення прогнозу клінічного перебігу виразкової хвороби шлунка, попередження ускладнень та вибору адекватного методу лікування авторами проведено морфофункціональні дослідження шлунка в 76 хворих. Комплексне клінічне дослідження та вивчення моторно-евакуаторної, секреторної функції й ступеня обсіменіння Helicobacter pylori шлунка дало можливість виявити групи ризику, прогнозувати клінічний перебіг захворювання, розробити показання до консервативного лікування, визначити його межі й своєчасно обгрунтувати необхідність хірургічного втручання в кожному конкретному випадку захворювання. Такий підхід до лікування хворих на виразкову хворобу шлунка дозволив значно покращити результати лікування та скоротити терміни реабілітації хворих із 45 до ЗО днів
The Management of Multicultural Members of Registered Student Organization (RSO) by Observing Two Groups: Volunteer Illini Projects (RSO1) and Dance 2XS Caliente (RSO2) at UIUC
Poster Presentation for EUI Spring 2017 Student Conference, concerning multicultural registered student organizations.Ope
Automated bow shock and magnetopause boundary detection with Cassini using threshold and deep learning methods
Two algorithms set for automatic detection of bow shock (BS) and magnetopause (MP) boundaries at Saturn using in situ magnetic field and plasma data acquired by the Cassini spacecraft are presented. Traditional threshold-based and modern deep learning algorithms were investigated for the task of boundary detection. Sections of Cassini’s orbits were pre-selected based on empirical BS and MP boundary models, and from outlier detection in magnetic field data using an autoencoder neural network. The threshold method was applied to pre-selected magnetic field and plasma data independently to compute parameters to which a threshold was applied to determine the presence of a boundary. The deep learning method used a type of convolutional neural network (CNN) called ResNet on images of magnetic field time series data and electron energy-time spectrograms to classify the presence of boundaries. 2012 data were held out of the training data to test and compare the algorithms on unseen data. The comparison showed that the CNN method applied to plasma data outperformed the threshold method. A final multiclass CNN classifier trained on plasma data obtained F1 scores of 92.1% ± 1.4% for BS crossings and 84.7% ± 1.9% for MP crossings on a corrected test dataset (from use of a bootstrap method). Reliable automated detection of boundary crossings could enable future spacecraft experiments like the PEP instrument on the upcoming JUICE spacecraft mission to dynamically adapt the best observing mode based on rapid classification of the boundary crossings as soon as it appears, thus yielding higher quality data and improved potential for scientific discovery
Productive cultural capital as an institutional means of ensuring the modernization process of the national economy
Розкрито процес трансформації ролі економіки в організації суспільства, періодичних змін
парадигм її розвитку протягом історії, місце у цих перетвореннях різних форм капіталу. Досліджено вплив на
формування економічної реальності як об’єктивних чинників, так і процесів, зумовлених волюнтаристичним
лобіюванням інтересів найбільших власників капіталів. Здійснено аналіз відмінних мотивів, якими керуються
суб’єкти економічної взаємодії залежно від рівня їх володіння важливими ресурсами. Проаналізовано боротьбу
різних видів капіталу, їх власників між собою за доходи, вплив, домінування, владу, яка супроводжується
періодичною зміною панівних еліт, що опираються на різні за змістом активи. Виявлено вичерпання
потенціалу сучасної парадигми розвитку економіки, де утвердився в якості панівного фіктивний капітал, в
основі якого рента, імітація корисної для суспільства діяльності, стимулювання штучних потреб, що
супроводжується одночасним експонентним наростанням кризових явищ відразу у низці важливих для
суспільства сфер його життєдіяльності. Встановлено необхідність зміни парадигми розвитку, сформованої
ще у період Нового часу і переорієнтування на випереджаючий розвиток продуктивного культурного капіталу.
Актуалізовано важливість визначення перспективних цілей, розроблення стратегій їх досягнення й переходу
національної економіки від рефлекторного реагування на проблеми чи зміну споживацького попиту на
прийняття рішень і формування комплексу дій відповідно до якнайшвидшого досягнення встановленої мети.
Розкрито руйнівну для сучасної цивілізації та навколишнього природного середовища орієнтацію на кількісні
параметри зростання та необхідність переорієнтування на виробництво матеріальних благ максимально
довготривалого використання, замкнених циклів виробництва та розвиток культурного потенціалу людей
замість нагромадження знаків багатства, яке має тенденцію до їх концентрації у вузького кола суб’єктів
економічної діяльності, породжуючи монополістичні тенденції вже у масштабах глобалізованої економіки.The article reveals the process of transformation of the role of the economy in the organization
of society, periodic changes in the paradigms of its development throughout history, the place in these transformations of various forms of capital, the studied influence on the formation of economic reality, both
objective factors and processes caused by the voluntarist lobbying of the interests of the largest capital owners.
An analysis of different motives, which are guided by subjects of economic interaction, depending on the level of
their ownership of important resources, is carried out. The struggle of different types of capital and their owners
among themselves for income, influence, dominance, and power, which is accompanied by a periodic change of
ruling elites based on assets of different content, is analyzed. The exhaustion of the potential of the modern
paradigm of economic development, where fictitious capital, which is based on rent, imitation of activities useful
to society, stimulation of artificial needs, accompanied by the simultaneous exponential growth of crisis
phenomena in a number of important spheres of societyʼs life activity, has been identified as the dominant one.
The need to change the paradigm of development, formed in the period of the New Age and reorientation to the
anticipatory development of productive cultural capital, has been established. The importance of defining
prospective goals, developing strategies for their achievement, and transitioning the national economy from a
reflexive response to problems or changes in consumer demand to decision-making and the formation of a set of
actions in accordance with the fastest possible achievement of the set goal has been updated. It is revealed that
the focus on quantitative parameters of growth and the need to reorientate on the production of material goods of
maximum long-term use, closed production cycles and the development of the cultural potential of people instead
of the accumulation of signs of wealth, which tends to their concentration in a narrow circle of subjects, are
destructive for modern civilization and the natural environment economic activity, giving rise to monopolistic
tendencies already on the scale of the globalized economy
Boron-Made N2: Realization of a B≡B Triple Bond in the B2Al3− Cluster
Until now, all B≡B triple bonds have been achieved by adopting two ligands in the L→B≡B←L manner. Herein, we report an alternative route of designing the B≡B bonds based on the assumption that by acquiring two extra electrons, an element with the atomic number Z can have properties similar to those of the element with the atomic number Z+2. Specifically, we show that due to the electron donation from Al to B, the negatively charged B≡B kernel in the B2Al3− cluster mimics a triple N≡N bond. Comprehensive computational searches reveal that the global minimum structure of B2Al3− exhibits a direct B–B distance of 1.553 Å, and its calculated electron vertical detachment energies are in excellent agreement with the corresponding values of the experimental photoelectron spectrum. Chemical bonding analysis revealed one σ and two π bonds between the two B atoms, thus confirming a classical textbook B≡B triple bond, similar to that of N2
Anti-histone H1 IgGs possess proliferative activity towards human T-leukaemia cem cells
The aim of this study was to characterize the proliferative activity of the anti-histone H1 IgGs towards human T-leukaemia CEM cells. Materials and Methods: Anti-histone H1 IgGs were purified from blood serum of systemic lupus erythematosus patients by precipitation of serum proteins with 50% ammonium sulfate followed by a sequential affinity chromatography on Protein GSepharose and histone H1-Sepharose columns. To avoid contamination with other proteins, anti-histone H1 IgGs were subjected to strongly acidic pH 2.0 during gel filtration through HPLC column. The effects of the anti-histone H1 IgGs on cell viability and cell cycle were tested by MTS-assay and flow cytometry, correspondingly. The cross-reactivity of the anti-histone H1 antibodies towards heterogenetic and cellular antigens was evaluated by Western-blot analysis. Results: It was found that incubation of CEM cells with the HPLC-purified anti-histone H1 IgGs resulted in significant stimulation of cell growth by 46% after 48 h of incubation. These IgGs possess an antigenic poly-specificity to positively charged heterogenetic antigens and different cellular antigens. FITC-labeled and biotinylated anti-histone H1 IgGs are internalized by CEM cells and preferentially accumulated in the cytoplasm. Conclusion: The anti-histone H1 IgGs are shown to internalize human T-leukemia CEM and stimulate their proliferation. These IgGs are polyspecific toward cellular antigens
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