7,449 research outputs found

    Differences in Relationship and Sexual Satisfaction and Social Support Between Only Lesbian, Mostly Lesbian, and Bisexual Women

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    Research suggests relationship and sexual satisfaction and social support are correlated with components of well-being such as anxiety, depression, and physical health. Differences in relationship and sexual satisfaction and social support have been identified between sexual minority women (SMW; i.e., lesbian and bisexual) and heterosexual women. However, classifying SMW into a single group may mask important differences. Further research is needed to better understand the differences in relationship and sexual satisfaction and social support between subgroups of SMW. Thus, the purpose of the present study was to examine differences in these constructs between women who identify as only lesbian, mostly lesbian, and bisexual. Participants were 427 partnered sexual minority women (Mage = 24.66; 84.8% White; 46.8% only lesbian; 34.2% mostly lesbian; 19% bisexual) recruited from social media to complete an online survey consisting of measures of relationship, health, and related factors as part of a larger study. A one-way ANOVA revealed statistically significant differences between only lesbian, mostly lesbian, and bisexual women in relationship satisfaction (p=.021), sexual satisfaction (p=.049), and social support (p=.034). Post-hoc pairwise comparisons revealed women who identified as only lesbian reported better relationship satisfaction (p=.007), sexual satisfaction (p=.015), and social support (p=.010) than women who identified as mostly lesbian. There were no differences between bisexual women and women who identified as either only lesbian or mostly lesbian. These findings identified important differences between subgroups of SMW, with women who identify as mostly lesbian reporting the lowest relationship and sexual satisfaction and social support. This study provides further evidence that collapsing across identities within the broad category of SMW may mask meaningful subgroup differences. Additional research is needed to further explore disparities in well-being among subsections of SMW. Findings may help identify important protective factors for mental and physical health and well-being specific to SMW of different identities.https://digitalcommons.odu.edu/gradposters2023_sciences/1007/thumbnail.jp

    The Effect of Pre-Harvest Application of Pectic Oligosaccharides and Abscisic Acid on Technological Ripening and Anthocyanin Profile of ‘Syrah’ Must and Grapes Grown in a Warm Climate

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    The progressive increase of environmental temperature as a consequence of climate change is a challengefor the wine industry. Elevated temperatures during grape ripening affect the development of grape skincolor by inhibiting the synthesis of pigments and promoting their degradation, which causes an imbalancein the chromatic quality of must and red wine. The application of pectic oligosaccharides (POs) and abscisicacid (ABA) triggers the phenylpropanoid pathway and increases the color index in grapes. Since the atharvestpigments and phenolic compounds are determinant for wine quality, this work addressed the preharvestapplication of POs and ABA as an in-field strategy for improving the quality of Syrah must andgrapes grown in a warm climate. The color development, physicochemical parameters, phenolic content,and pigments in berries and must were evaluated. Results showed POs and ABA improved berry colordevelopment and anthocyanin content during ripening. Musts from POs-treated berries exhibited thehighest phenols concentration and the most intense color, related to higher chroma values and anthocyanincontent, particularly delphinidin, petunidin, and malvidin 3-glucosides, while ABA improved must tonalityby reducing the hue angle. In summary, POs and ABA application at verĂĄison, differentially modulatedthe technological ripening of Syrah grapes and can be an alternative to conventional agrochemicals topreserve the quality of musts elaborated from grapes grown in warm climates, by increasing the content ofphenolic compounds and enhancing berry skin color development through the differential accumulationof anthocyanins

    AB0690 Antiphospholipid antibodies and spondyloarthritis. Truth or myth? Our results in a third level hospital

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    [EN] The importance of antiphospholipid antibodies and their clinical involvement in thrombotic phenomena, isolated or associated with certain autoimmune diseases such as systemic lupus erythematosus, is known. However, in spondyloarthritis (SpA) there is little published data about it.S

    Influence of conservation tillage and soil water content on crop yield in dryland compacted alfisol of Central Chile

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    Chilean dryland areas of the Mediterranean climate region are characterized by highly degraded and compacted soils, which require the use of conservation tillage systems to mitigate water erosion as well as to improve soil water storage. An oat (Avena sativa L. cv. Supernova-INIA) - wheat (Triticum aestivum L. cv. Pandora-INIA) crop rotation was established under the following conservation systems: no tillage (Nt), Nt + contour plowing (Nt+Cp), Nt + barrier hedge (Nt+Bh), and Nt + subsoiling (Nt+Sb), compared to conventional tillage (Ct) to evaluate their influence on soil water content (SWC) in the profile (10 to 110 cm depth), the soil compaction and their interaction with the crop yield. Experimental plots were established in 2007 and lasted 3 yr till 2009 in a compacted Alfisol. At the end of the growing seasons, SWC was reduced by 44 to 51% in conservation tillage systems and 60% in Ct. Soil water content had a significant (p < 0.05) interaction with tillage system and depth; Nt+Sb showed lower SWC between 10 to 30 cm, but higher and similar to the rest between 50 to 110 cm except for Ct. Although, SWC was higher in conservation tillage systems, the high values on soil compaction affected yield. No tillage + subsoiling reduced soil compaction and had a significant increment of grain yield (similar to Ct in seasons 2008 and 2009). These findings show us that the choice of conservation tillage in compacted soils of the Mediterranean region needs to improve soil structure to obtain higher yields and increment SWC

    Risk Factors for Soil-Transmitted Helminth Infections during the First 3 Years of Life in the Tropics; Findings from a Birth Cohort.

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    Background: Soil-transmitted helminths (STH) infect more than 2 billion humans worldwide, causing significant morbidity in children. There are few data on the epidemiology and risk factors for infection in pre-school children. To investigate risk factors for infection in early childhood, we analysed data prospectively collected in the ECUAVIDA birth cohort in Ecuador. Methods and Findings: Children were recruited at birth and followed up to 3 years of age with periodic collection of stool samples that were examined microscopically for STH parasites. Data on social, demographic, and environmental risk factors were collected from the mother at time of enrolment. Associations between exposures and detection of STH infections were analysed by multivariable logistic regression. Data were analysed from 1,697 children for whom a stool sample was obtained at 3 years. 42.3% had at least one STH infection in the first 3 years of life and the most common infections were caused by A. lumbricoides (33.2% of children) and T. trichiura (21.2%). Hookworm infection was detected in 0.9% of children. Risk of STH infection was associated with factors indicative of poverty in our study population such as Afro-Ecuadorian ethnicity and low maternal educational level. Maternal STH infections during pregnancy were strong risk factors for any childhood STH infection, infections with either A. lumbricoides or T. trichiura, and early age of first STH infection. Children of mothers with moderate to high infections intensities with A. lumbricoides were most at risk. Conclusions: Our data show high rates of infection with STH parasites during the first 3 years of life in an Ecuadorian birth cohort, an observation that was strongly associated with maternal STH infections during pregnancy. The targeted treatment of women of childbearing age, in particular before pregnancy, with anthelmintic drugs could offer a novel approach to the prevention of STH infections in pre-school children

    Instability of hyper-compact Kerr-like objects

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    Viable alternatives to astrophysical black holes include hyper-compact objects without horizon, such as gravastars, boson stars, wormholes and superspinars. The authors have recently shown that typical rapidly-spinning gravastars and boson stars develop a strong instability. That analysis is extended in this paper to a wide class of horizonless objects with approximate Kerr-like geometry. A detailed investigation of wormholes and superspinars is presented, using plausible models and mirror boundary conditions at the surface. Like gravastars and boson stars, these objects are unstable with very short instability timescales. This result strengthens previous conclusions that observed hyper-compact astrophysical objects with large rotation are likely to be black holes.Comment: 15 pages, 3 figures. To be published in CQ

    On the origin of the Norwegian lemming.

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    The Pleistocene glacial cycles resulted in significant changes in species distributions, and it has been discussed whether this caused increased rates of population divergence and speciation. One species that is likely to have evolved during the Pleistocene is the Norwegian lemming (Lemmus lemmus). However, the origin of this species, both in terms of when and from what ancestral taxon it evolved, has been difficult to ascertain. Here, we use ancient DNA recovered from lemming remains from a series of Late Pleistocene and Holocene sites to explore the species' evolutionary history. The results revealed considerable genetic differentiation between glacial and contemporary samples. Moreover, the analyses provided strong support for a divergence time prior to the Last Glacial Maximum (LGM), therefore likely ruling out a postglacial colonization of Scandinavia. Consequently, it appears that the Norwegian lemming evolved from a small population that survived the LGM in an ice-free Scandinavian refugium

    Enhancer Sequence Variants and Transcription-Factor Deregulation Synergize to Construct Pathogenic Regulatory Circuits in B-Cell Lymphoma

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    SummaryMost B-cell lymphomas arise in the germinal center (GC), where humoral immune responses evolve from potentially oncogenic cycles of mutation, proliferation, and clonal selection. Although lymphoma gene expression diverges significantly from GC B cells, underlying mechanisms that alter the activities of corresponding regulatory elements (REs) remain elusive. Here we define the complete pathogenic circuitry of human follicular lymphoma (FL), which activates or decommissions REs from normal GC B cells and commandeers enhancers from other lineages. Moreover, independent sets of transcription factors, whose expression was deregulated in FL, targeted commandeered versus decommissioned REs. Our approach revealed two distinct subtypes of low-grade FL, whose pathogenic circuitries resembled GC B or activated B cells. FL-altered enhancers also were enriched for sequence variants, including somatic mutations, which disrupt transcription-factor binding and expression of circuit-linked genes. Thus, the pathogenic regulatory circuitry of FL reveals distinct genetic and epigenetic etiologies for GC B-cell transformation
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