H-alpha Kinematics of the SINGS Nearby Galaxies Survey. II

This is the second part of an H-alpha kinematics follow-up survey of the Spitzer Infrared Nearby Galaxies Survey (SINGS) sample. The aim of this program is to shed new light on the role of baryons and their kinematics and on the dark/luminous matter relation in the star forming regions of galaxies, in relation with studies at other wavelengths. The data for 37 galaxies are presented. The observations were made using Fabry-Perot interferometry with the photon-counting camera FaNTOmM on 4 different telescopes, namely the Canada-France-Hawaii 3.6m, the ESO La Silla 3.6m, the William Herschel 4.2m, and the Observatoire du mont Megantic 1.6m telescopes. The velocity fields are computed using custom IDL routines designed for an optimal use of the data. The kinematical parameters and rotation curves are derived using the GIPSY software. It is shown that non-circular motions associated with galactic bars affect the kinematical parameters fitting and the velocity gradient of the rotation curves. This leads to incorrect determinations of the baryonic and dark matter distributions in the mass models derived from those rotation curves.Comment: 18 pages, 5 figures, 4 tables. Accepted for publication in MNRAS. All high-res. figures are available at http://www.astro.umontreal.ca/fantomm/singsII

Light self-focusing in the atmosphere:thin window model

Ultra-high power (exceeding the self-focusing threshold by more than three orders of magnitude) light beams from ground-based laser systems may find applications in space-debris cleaning. The propagation of such powerful laser beams through the atmosphere reveals many novel interesting features compared to traditional light self-focusing. It is demonstrated here that for the relevant laser parameters, when the thickness of the atmosphere is much shorter than the focusing length (that is, of the orbit scale), the beam transit through the atmosphere in lowest order produces phase distortion only. This means that by using adaptive optics it may be possible to eliminate the impact of self-focusing in the atmosphere on the laser beam. The area of applicability of the proposed "thin window" model is broader than the specific physical problem considered here. For instance, it might find applications in femtosecond laser material processing

Atomic and Molecular Gas Components in Spiral Galaxies of the Virgo Cluster

Based on two models, we investigate the molecular-to-atomic gas ratio in Virgo cluster galaxies in comparison with field galaxies. We show that the enhanced metallicity for cluster members and the ram pressure stripping of atomic gas from the disk periphery cannot fully explain the observed gas component ratios. The additional environmental factors affecting the interstellar medium and leading to an increase in the molecular gas fraction should be taken into account for cluster galaxies.Comment: 11 pages, 4 figure

Optimized testing strategy for the diagnosis of GAA-FGF14 ataxia/spinocerebellar ataxia 27B

Dominantly inherited GAA repeat expansions in FGF14 are a common cause of spinocerebellar ataxia (GAA-FGF14 ataxia; spinocerebellar ataxia 27B). Molecular confirmation of FGF14 GAA repeat expansions has thus far mostly relied on long-read sequencing, a technology that is not yet widely available in clinical laboratories. We developed and validated a strategy to detect FGF14 GAA repeat expansions using long-range PCR, bidirectional repeat-primed PCRs, and Sanger sequencing. We compared this strategy to targeted nanopore sequencing in a cohort of 22 French Canadian patients and next validated it in a cohort of 53 French index patients with unsolved ataxia. Method comparison showed that capillary electrophoresis of long-range PCR amplification products significantly underestimated expansion sizes compared to nanopore sequencing (slope, 0.87 [95% CI, 0.81 to 0.93]; intercept, 14.58 [95% CI, − 2.48 to 31.12]) and gel electrophoresis (slope, 0.84 [95% CI, 0.78 to 0.97]; intercept, 21.34 [95% CI, − 27.66 to 40.22]). The latter techniques yielded similar size estimates. Following calibration with internal controls, expansion size estimates were similar between capillary electrophoresis and nanopore sequencing (slope: 0.98 [95% CI, 0.92 to 1.04]; intercept: 10.62 [95% CI, − 7.49 to 27.71]), and gel electrophoresis (slope: 0.94 [95% CI, 0.88 to 1.09]; intercept: 18.81 [95% CI, − 41.93 to 39.15]). Diagnosis was accurately confirmed for all 22 French Canadian patients using this strategy. We also identified 9 French patients (9/53; 17%) and 2 of their relatives who carried an FGF14 (GAA)≥250 expansion. This novel strategy reliably detected and sized FGF14 GAA expansions, and compared favorably to long-read sequencing

Mutations in the Mitochondrial Methionyl-tRNA Synthetase Cause a Neurodegenerative Phenotype in Flies and a Recessive Ataxia (ARSAL) in Humans

The study of Drosophila neurodegenerative mutants combined with genetic and biochemical analyses lead to the identification of multiple complex mutations in 60 patients with a novel form of ataxia/leukoencephalopathy

Weaving our way towards a new generation of fibre-optic chemical sensors based on spider silk

From the spider's perspective, silk is not only a building material but also a safety net, a weapon and a sensory organ to detect the presence of preys on its web. Indeed, this primeval material has been shaped over hundreds of millions of years by spiders to create a myriad of silk fibre types with different level of toughness, elasticity, stickiness depending on its attributed function in the web. From a human perspective, scientists are currently working on harnessing all the extraordinary properties of this material for applications spiders would never thought of, from biocompatible tissue engineering (enhancement of skin regeneration and nerve guides) to biodegradable electronics and development of specialised textile and composites. However, the potential of using spider silk fibre for chemical sensing has been overlooked. In this communication, we will explore the potential of using spider silk as a new type of fibre optic chemical sensor in a fully bio-inspired approach

Exploring the use of native spider silk as an optical fibre for chemical sensing

A spider uses up to seven different types of silk, all having specific functions, as building material, weapon, and sensory organ to detect the presence of preys on its web. Recently, scientists have put under the limelight the extraordinary properties of this ancient material. Indeed, native silk, directly extracted from spiders, is a tough, biodegradable, and biocompatible thread used mainly for tissue engineering and textile applications. Blessed with outstanding optical properties, this protein strand can also be used as a bioresorbable optical fiber and is, moreover, intrinsically sensitive to chemical compounds. In this communication, the waveguiding properties of native dragline silk are assessed and a pioneering proof-of-concept experiment using pristine spider silk as an optical fiber to measure humidity content is demonstrated. The feasibility of using silk-based optical fiber chemical sensors is also discussed

Space-based application of the CAN laser to LIDAR and orbital debris remediation

Development of pulsed lasers for space-based science missions entail many additional challenges compared to terrestrial experiments. For systems requiring short pulses ≪1 ns with energies >100 mJ and fast repetition rates >10 kHz there are currently few if no laser architectures capable of operating with high electrical efficiency >20% and have good system stability. The emergence of a mulit-channel fiber-based Coherent-Amplifying-Network or CAN laser potentially enables such capability for space based missions. Here in this article we present an analysis of two such missions scaling up in pulse energy from ≈100 mJ for a supercontinuum LIDAR application utilising atmospheric filamentation to the higher energy demands needed for space debris remediation requiring ≈10 J pulses. This scalability of the CAN laser provides pathways for development of the core science and technology where many new novel space applications can be made possible

Deep Fabry-Perot Halpha Observations of NGC 7793: a Very Extended Halpha Disk and a Truly Declining Rotation Curve

28 pages, 8 figures. Accepted for publication in AJInternational audienceDeep Halpha observations of the Sculptor Group galaxy NGC 7793 were obtained on the ESO 3.60m and the Marseille 36cm telescopes at La Silla, Chile. Halpha emission is detected all the way to the edge of the HI disk, making of the HII disk of NGC 7793 one of the largest ever observed in a quiet non-AGN late-type system. Even in the very outer parts, the HII ionizing sources are probably mainly internal (massive stars in the disk) with an unlikely contribution from the extragalactic ionizing background. The Halpha kinematics confirms what had already been seen with the HI observations: NGC 7793 has a truly declining rotation curve. However, the decline is not Keplerian and a dark halo is still needed to explain the rotation velocities in the outer parts