1,432 research outputs found
The building stones and slates of Killin : an investigation of stone for the built heritage
The village of Killin lies in an area of dramatic landscape and mountain scenery. The use of local stone
in the buildings gives a direct connection to this landscape and reflects the local geology, comprising
mostly metamorphic rocks of Precambrian age –dominantly limestone, meta-sandstone, mica schist
and meta-igneous rocks. All of these (with the exception of the Loch Tay Limestone which was used for
soil improvement) were used in buildings and structures within the Killin Conservation Area.
The stone masonry in the village is classified into five categories; (1) cottages (mostly harled) built of
random rubble from field and river boulders and surface rock outcrops, (2) two storey buildings with
irregular coursed rubble walls of meta-sandstone and mica schist with large dressings of silver-grey
slabs of actinolite schist, (3) and (4) larger late 19th century buildings with dressings of Central Belt
sandstone used in combination with squared rubble walling of local actinolite schist and metasandstone.
The 5th masonry category represents relatively late buildings constructed using distinctive
imported stone types (e.g. whinstone, granite, red sandstone). These categories are broadly
chronological in order and reflect the development of architectural form along with improving
transportation of materials over time
Metatarsophalangeal joint pain in psoriatic arthritis: a cross-sectional study
Methods. Thirty-four consecutive patients with PsA (mean age 45.3 years, 65% female, mean disease duration 9.9 years) and 22 control participants (mean age 37.9 years, 64% female) underwent clinical and US examination to determine the presence of pain, swelling, synovitis, erosions, effusions and submetatarsal bursae at the MTP joints. Mean barefoot peak plantar pressures were determined at each MTP joint. Levels of pain, US-determined pathology and peak pressures were compared between groups. Binary logistic regression was used to identify demographic, clinical examination-derived, US-derived and plantar pressure predictors of pain at the MTP joints in the PsA group.
Results. The presence of pain, deformity, synovitis, erosions (P < 0.001) and submetatarsal bursae and peak plantar pressure at MTP 3 (P < 0.05) were significantly higher in the PsA group. MTP joint pain in PsA was independently predicted by high BMI, female gender and the presence of joint subluxation, synovitis and erosion.
Conclusion. These results suggest local inflammatory and structural factors, together with systemic factors (gender, BMI), are predominantly responsible for painful MTP joints in PsA, with no clear role for plantar pressure characteristics
Rising top-income persistence in Australia: evidence from income tax data
We use a new Australian longitudinal income tax dataset, Alife, covering 1991–2017, to examine levels and trends in the persistence in top-income group membership, focussing on the top 1%. We summarize persistence in multiple ways, documenting levels and trends in rates of remaining in top-income groups; re-entry to the top; the income changes associated with top-income transitions; and we also compare top-income persistence rates for annual and ‘permanent’ incomes. Regardless of the perspective taken, top-income persistence increased markedly over the period, with most of the increase occurring in the mid-2000s and early 2010s. In the mid- to late2010s, Australian top-income persistence rates appear to have been near the top of the range of tax-data estimates for other countries. Using univariate breakdowns and multivariate regression, we show that the rise in top-income persistence in Australia was experienced by many population subgroups
Prognostic significance of high-grade dysplasia in colorectal adenomas.
Aim  Colonoscopy to detect and remove polyps has contributed to a reduction in colorectal carcinoma. Three-year follow up is recommended for patients considered to be at high risk (at least three adenomas, adenoma ≥ 1 cm, villous or high-grade features). Our study focused on patients diagnosed with high-grade dysplasia with regard to initial management and follow up. Method  A search of patients who had had endoscopic removal of a high-grade adenoma was carried out. Patients with the following were excluded: follow up of \u3c 1 year, polyposis syndromes, prior colon cancer and a diagnosis of adenocarcinoma within 6 months following initial diagnosis. Results  Eighty-three patients treated between 1999 and 2007 for high-grade dysplasia (HGD) in a colorectal adenoma were identified. Over a median follow-up period of 4 years, 53 (64%) developed further adenomatous polyps. Among these, 7% had an adenoma with HGD or an adenocarcinoma. In all these patients, the initial high-grade adenoma was \u3e 1 cm in diameter. Initial follow-up colonoscopy was performed on average 7 months following the initial diagnosis. Ten per cent of patients underwent prophylactic segmental resection, and 6% received argon laser therapy. Conclusion  The study demonstrates that patients who have a colorectal adenoma \u3e 1 cm with HGD may be at high risk of developing further adenomas with HGD or carcinoma. Close follow up is warranted
Surface-reconstructed Icosahedral Structures for Lead Clusters
We describe a new family of icosahedral structures for lead clusters. In
general, structures in this family contain a Mackay icosahedral core with a
reconstructed two-shell outer-layer. This family includes the anti-Mackay
icosahedra, which have have a Mackay icosahedral core but with most of the
surface atoms in hexagonal close-packed positions. Using a many-body glue
potential for lead, we identify two icosahedral structures in this family which
have the lowest energies of any known structure in the size range from 900 to
15000 lead atoms. We show that these structures are stabilized by a feature of
the many-body glue part of the interatomic potential.Comment: 9 pages, 8 figure
A Clinico-epidemiological Study Of Bites By Spiders Of The Genus Phoneutria.
From January, 1984 to December, 1996, 422 patients (ages 9 m-99 y, median 29 y) were admitted after being bitten by spiders which were brought and identified as Phoneutria spp. Most of the bites occurred at March and April months (29.2%), in the houses (54.5%), during the day (76.5%), and in the limbs (feet 40.9%, hands 34.3%). Upon hospital admission, most patients presented only local complaints, mainly pain (92.1%) and edema (33.1%) and were classified as presenting mild (89.8%), moderate (8.5%) and severe (0.5%) envenomation. Few patients (1.2%) did not present signs of envenomation. Severe accidents were only confirmed in two children (9 m, 3 y). Both developed acute pulmonary edema, and the older died 9 h after the accident. Patients more than 70 year-old had a significantly greater (p<0.05) frequency of moderate envenomations compared to the 10-70-year-old individuals. Proceedings to relief local pain were frequently performed (local anesthesia alone 32.0%, local anesthesia plus analgesics 20.6% and oral analgesics alone 25. 1%). Only 2.3% of the patients (two cases classified as severe and eight as moderate, eight of them in children) were treated with i.v. antiarachnid antivenom. No antivenom early reaction was observed. In conclusion, accidents involving the genus Phoneutria are common in the region of Campinas, with the highest risk groups being children under 10 years of age and adults over 70 years of age. Cases of serious envenomation are rare (0.5%).4217-2
Constraints on narrow exotic states from K+p and K0_Lp scattering data
We consider the effect of exotic S=+1 resonances Theta+ and Theta++ on K+p
elastic scattering data (total cross section) and the process K0_Lp-->K0_Sp.
Data near the observed Theta+(1540) are examined for evidence of additional
states. The width limit for a Theta++ state is reconsidered and shown to be
much less than 1 MeV.Comment: 4 pages, 3 eps figures; minor corrections, one fig adde
Insulin stimulation of glucose transport in isolated rat adipocytes. Functional evidence for insulin activation of intrinsic transporter activity within the plasma membrane
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