2,066 research outputs found

    A study of local approximation for polarization potentials

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    We discuss the derivation of an equivalent \textit{l}-independent polarization potential for use in the optical Schr\"{o}dinger equation that describes the elastic scattering of heavy ions. Three diffferent methods are used for this purpose. Application of our theory to the low energy scattering of the halo nucleus 11^{11}Li from a 12^{12}C target is made. It is found that the notion of \textit{l}-independent polarization potential has some validity but can not be a good substitute for the \textit{l}-dependent local equivalent Feshbach polarization potential.Comment: 8 pages, 4 figure

    Interplay of static and dynamic effects in 6He+ 238U Fusion

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    We investigate the influence of the neutron halo and the breakup channel in 6He + 238U fusion at near-barrier energies. To include static effects of the 2n-halo in 6He nuclei, we use a single-folding potential obtained from an appropriate nucleon-238U interaction and a realistic 6He density. Dynamical effects arising from the breakup process are then included through coupled-channel calculations. These calculations suggest that static effects dominate the cross section at energies above the Coulomb barrier, while the sub-barrier fusion cross section appears to be determined by coupling to the breakup channel. This last conclusion is uncertain due to the procedure employed to measure the fusion cross-section.Comment: 13 pages, 4 figure

    IgG4-related hypophysitis: a retrospective cohort study

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    Purpose: IgG4-related hypophysitis (IgG4-RH) is a rare chronic inflammatory condition of the pituitary gland. This study reports the presentation, management and outcomes for patients with histologically proven IgG4-related hypophysitis. Methods: A prospectively maintained electronic database was searched over a 14-year period from 1 January 2007 to 31 December 2020 at a single academic centre to identify all patients with a histological diagnosis of IgG4-RH. A retrospective case note review from electronic health records was conducted for each case to extract data on their presentation, management and outcomes. Results: A total of 8 patients (5 male) with a median age of 51 years were identified. The most common presenting symptoms were headache (4/8; 50%), fatigue (3/8; 37.5%) and visual impairment (2/8; 25%). Three patients were initially treated with high-dose steroids aiming for reduction of the pituitary mass. However, ultimately all patients underwent transsphenoidal surgery. Post-operative changes included radiological reduction in pituitary mass in all patients that had imaging (7/7; 100%), improvement in vision (1/2; 50%), residual thick pituitary stalk (5/7; 71.4%), persistent anterior hypopituitarism (4/8; 50%) and panhypopopituitarism including diabetes insipidus (3/8; 37.5%). Conclusions: IgG4-RH is an increasingly recognised entity presenting with a variety of symptoms and signs. Clinical presentation is similar to other forms of hypophysitis. It is therefore important to consider IgG4-RH as a differential and to have a low threshold for pituitary biopsy, the diagnostic gold standard. The diagnosis of IgG4-RH will guide decisions for additional workup for IgG4-related disease, multi-disciplinary team involvement and follow-up

    Clinical Prediction of Blood Parameters Associated with Breast, Colon, Thyroid, Ovarian, and Prostate Cancer

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    Cancer is a cellular change caused by uncontrolled cell growth and division. This disease develops from the growth of abnormal cells that have the potential to invade or spread to other parts of the body. The aim of this study was to investigate the relationship between blood parameters (e.g., Mean corpuscular volume (MCV), Mean corpuscular hemoglobin (MCH), Mean Corpuscular Hemoglobin Concentration (MCHC), Haemoglobin (HGB), White Blood Cell (WBC), and Red Blood Cell (RBC)) and different types of cancer. Breast cancer, thyroid gland cancer, ovarian cancer, testicular cancer, brain tumors as well as other types of cancer are based on the cell of the tissue found on or in the body. Any of these types of cancer are associated with a variety of health issues that put the patient's life in danger. Performing the complete blood count (CBC) test prior to or after a cancer diagnosis is necessary as abnormalities in the body can cause blood component rates to either increase or decrease, depending on the type of cancer, the patient's physiological mechanism, and the structural component. Since the CBC test belongs to hematology, drawing a blood sample and putting it into the anticoagulant tube for testing were preferred. In this study, the blood components of almost all patients were normal except for a few of them which may be due to other medical and biological factors. There is a significant relationship between blood parameters and cancer types.&nbsp

    Integrating water-energy-nexus in carbon footprint analysis in water utility company

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    The purpose of this paper is to highlight the water-energy-nexus within the context of carbon footprint methodology and water utility industry. In particular, the carbon management for water utility industry is crucial in reducing carbon emission within the upstream water distribution system. The concept of water-energy nexus alone however can be misleading due to exclusion of indirect and embodied energy involved in the water production. The study highlights the total energy use within water supply system as well as embedded carbon emission through carbon footprint methodology. The case study approach is used as a research method. The carbon footprint analysis includes data collection from water utility company; and data identification of direct and indirect carbon emission from corporation operation. The result indicates that the indirect and embodied energy may not be significant in certain operation area but the energy use may be ambiguous when these elements are excluded. Integrating carbon footprint methodology within the water supply system can improve the understanding on water-energy-nexus when direct and indirect energy use is included in the analysis. This paper aims to benefit academics, government agencies and particularly water utility companies in integrating carbon footprint analysis in water production

    Craniopharyngioma in children: trends from a third consecutive single-center cohort study

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    OBJECTIVE: The management of children with craniopharyngioma has evolved over time, with a trend toward less invasive neurosurgical approaches as surgeons have sought to balance oncological control and treatment-related morbidity. To this end, the aim of this study was to evaluate the safety and effectiveness of the current management of children with craniopharyngioma compared to the previous management methods used at the authors’ treatment center. METHODS: A prospectively maintained database was searched over a 14-year period between January 1, 2005, and December 31, 2018, to identify all children 17 years of age or younger with a new diagnosis of craniopharyngioma. A retrospective case note review was performed for each child to extract data on the presentation, investigation, treatment, and outcome of their illness. Morbidity was assessed in the same fashion as in previous cohorts, according to the following categories: visual loss, pituitary dysfunction, hypothalamic dysfunction, neurological deficits, and cognitive impairment. RESULTS: In total, 59 children were identified with craniopharyngioma during the study period. A total of 92 operations were performed, including cyst drainage (35/92; 38.0%), craniotomy and resection (30/92; 32.6%), and transsphenoidal resection (16/92; 17.4%). Approximately two-thirds of all operations were performed using image guidance (66/92; 71.7%) and one-third were performed using endoscopy (27/92; 29.3%). The majority of children had adjuvant therapy comprising proton beam therapy (18/59; 30.5%) or conventional radiotherapy (16/59; 27.1%). The median follow-up duration was 44 months (range 1–142 months), and approximately one-half of the children had no evidence of residual disease on MRI studies (28/59; 47.5%). Of the remaining 31 children, there was a reduction in the volume of residual disease in 8 patients (8/59; 13.6%), stable residual disease in 18 (18/59; 30.5%), and tumor growth in 5 patients (5/59; 8.5%). There was significantly reduced morbidity (p < 0.05) in all categories in the current cohort compared with our last cohort (1996–2004). CONCLUSIONS: The authors’ institutional experience of pediatric craniopharyngioma confirms a trend toward less invasive neurosurgical procedures, most of which are now performed with the benefit of image guidance or endoscopy. Moreover, the authors have identified an expanding role for more targeted radiotherapy for children with residual disease. These advances have allowed for tumor control comparable to that achieved in previous cohorts, but with significantly reduced morbidity and mortality

    Simple broadband circularly polarized monopole antenna with two asymmetrically connected U-shaped parasitic strips and defective ground plane

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    A simple compact broadband circularly polarized monopole antenna, which comprises a simple monopole, a modified ground plane with an implementing triangular stub and two asymmetrically connected U-shaped parasitic strips, is proposed. Simulation results show that the proposed compact antenna (0.62λo×0.68λo) achieves a 10-dB impedance bandwidth (IBW) of 111% (1.7 to 5.95 GHz) and a 3-dB axial ratio bandwidth (ARBW) of 61% (3.3–6.2 GHz) with a peak gain between 2.9–4 dBi for the entire ARBW. With its broad IBW and ARBW, compact size and simple structure, the proposed antenna is suitable for different wireless communications

    Synthesis of (cinnamate-zinc layered hydroxide) intercalation compound for sunscreen application

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    Background: Zinc layered hydroxide (ZLH) intercalated with cinnamate, an anionic form of cinnamic acid (CA), an efficient UVA and UVB absorber, have been synthesized by direct method using zinc oxide (ZnO) and cinnamic acid as the precursor. Results: The resulting obtained intercalation compound, ZCA, showed a basal spacing of 23.9 Å as a result of cinnamate intercalated in a bilayer arrangement between the interlayer spaces of ZLH with estimated percentage loading of cinnamate of about 40.4 % w/w. The UV–vis absorption spectrum of the intercalation compound showed excellent UVA and UVB absorption ability. Retention of cinnamate in ZLH interlayers was tested against media usually came across with sunscreen usage to show low release over an extended period of time. MTT assay of the intercalation compound on human dermal fibroblast (HDF) cells showed cytotoxicity of ZCA to be concentration dependent and is overall less toxic than its precursor, ZnO. Conclusions: (Cinnamate-zinc layered hydroxide) intercalation compound is suitable to be used as a safe and effective sunscreen with long UV protection effect
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