293 research outputs found

    How AI hype impacts the LGBTQ+ community

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    Hype around Artificial Intelligence (AI) has been a feature of this technology since its inception. However, the most recent wave of AI hype has been leveraged to encourage adoption of AI technologies that cause issues for marginalised communities. Hype is also a means to obfuscate real issues of bias, harm, and exploitation felt most sharply by marginalised communities when AI is implemented. This therefore raises the question of power imbalances as a feature of AI technologies as we currently know them. This paper will study the relationship of AI hype and marginalised communities, with particular emphasis on the LGBTQ + community, and look at the way that AI impacts on this community. This paper will pose two key questions: does hype affect marginalised communities, particularly hype around new technologies such as AI; and what impact does the LGBTQ + community experience as a result of hype. This paper will then move on to discuss areas that provide a focus for discourse of AI hype and the impact on the LGBTQ + community: policy and decision-making, the maintenance of the cisgender heteronormative (cishet) baseline, the ubiquity of a mythology of AI, and the role of market expansion

    Identification and discussion of selected Roman objects. In: Cook, Martin, Lawson, John A and McLaren, Dawn, 'Excavations and Interventions in and around Cramond Roman Fort and Annexe, 1976 to 1990'. Scottish Archaeology Internet Report 74

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    Cramond Roman Fort has been the focus of archaeological interest since the publication of John Wood’s history of the parish in the late 18th century, with a floruit of activity in the latter half of the 20th century. Playing an important part in this volume of work have been the excavations led by the late Mr Charlie Hoy (d 1991), an Edinburgh amateur archaeologist working principally with the Edinburgh Archaeological Field Society and latterly on his own. His excavations have recovered a wide range of evidence from the Mesolithic through the Roman and medieval periods up to the post-medieval development of Cramond House Estate. Hoy’s investigations have been hugely important to our understanding of the Roman fort’s associated annexe/extramural settlement, in particular providing new evidence for its origins in the Antonine period, and for Severan occupation, as well as uncovering a multi-phased road and associated wooden structures. In addition, the artefact assemblage further adds to the corpus from the site and includes an internationally significant sword pendant belonging to a beneficiarius (beneficiarii were troops on special service for the provincial governor) that demonstrates the presence of German troops at the fort, and perhaps hints at the presence of the emperor himself

    The querns from Phantassie and Eweford Cottages

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    Bilateral absence of the musculocutaneous nerve : implications for humerus fracture and atypical median nerve palsy

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    The absence of the musculocutaneous nerve represents a failure of the nerve to depart from the median nerve during early development. During a routine dissection of a 66-year-old white female cadaver, a bilateral absence of the musculocutaneous nerve was observed in the upper limbs. Muscles of the anterior flexor compartments of the arms including biceps brachii and brachialis were supplied by branches of the median nerve. The lateral cutaneous nerve of the forearm also branched from the median nerve. In a clinical case of a particularly high median nerve injury, a variation of an absent musculocutaneous nerve may not only result in typical median nerve palsy of the forearm and hand, but palsy in the arm that would manifest as deficiencies in both shoulder and elbow flexion as well as cutaneous sensory loss from the lateral forearm

    Art, Intuition, and Identity in RamĂłn y Cajal

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    In the history of neuroscience, Cajal stands tall. Many figures in the late 19th and early 20th centuries made major contributions to neuroscience-Sherrington, Ferrier, Jackson, Holmes, Adrian, and Békésy, to name a few. But in the public mind, Cajal is unique. His application of the Golgi method, with an array of histologic stains, unlocked a wealth of new knowledge on the structure and function of the brain. Here we argue that Cajal's success should not only be attributed to the importance of his scientific contributions but also to the artistic visual language that he created and to his pioneering self-branding, which exploited methods of the artist, including classical drawing and the new invention of photography. We argue that Cajal created his distinctive visual language and self-branding strategy by interweaving an ostensibly objective research product with an intimately subjective narrative about the brain and himself. His approach is evident in the use of photography, notably self-portraits, which furthered broad engagement initially inspired by his scientific drawings. Through his visual language, Cajal made an impact in art and culture far beyond the bounds of science, which has sustained his scientific legacy.</p

    'Hitting the spot': Developing individuals with lived-experience of health and social care as facilitators to deliver a course to enhance public involvement in research - a Welsh perspective

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    Health and Care Research Wales has a strategic aim to ensure public involvement and engagement is central to what we do and visible in all elements of it. As part of the ongoing development of the Health and Care Research Wales Training Programme a project was initiated to develop members of the public as facilitators to deliver a public involvement in research course. The project was undertaken in collaboration with Macmillan Cancer Support and was advertised via the Involving People Network in Wales. Three trainee facilitators were recruited, from 14 people that applied, to deliver a public involvement in research training course, the Building Research Partnerships course, as it was known then, originally developed for and by Macmillan Cancer Support. As members of the Involving People Network, the trainees were given training, mentorship, financial and administrative support to develop their role as facilitators over a two year period. This has been reciprocated with incredible commitment, ongoing course delivery in Wales, excellent course evaluations, course review and involvement in future planning. Through this project several benefits were realised, including developing the course content and its delivery and building the skills and confidence of the individual facilitators themselves. Additionally, and importantly, the project team found that patients and members of the public who are given appropriate training and support can greatly enhance a research training programme and act as highly effective ambassadors to further the cause of public involvement in research

    Prenatal and Early, but Not Late, Postnatal Exposure of Mice to Sidestream Tobacco Smoke Increases Airway Hyperresponsiveness Later in Life

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    Background Cigarette smoke exposure in utero and during early postnatal development increases the incidence of asthma and airway hyperresponsiveness (AHR) later in life, suggesting that a possible critical period of developmental sensitivity exists in the prenatal and early postnatal periods. Objective We investigated mechanisms of susceptibility during critical developmental periods to sidestream smoke (SS) exposure and evaluated the possible effects of SS on neural responses. Methods We exposed three different age groups of mice to either SS or filtered air (FA) for 10 consecutive days beginning on gestation day (GD) 7 by maternal exposure or beginning on postnatal day (PND) 2 or PND21 by direct inhalation. Lung function, airway substance P (SP) innervation, and nerve growth factor (NGF) levels in broncho alveolar lavage fluid were measured after a single SS exposure on PND59. Results Methacholine (MCh) dose response for lung resistance (RL) was significantly elevated, and dynamic pulmonary compliance (Cdyn) was significantly decreased, in the GD7 and PND2 SS exposure groups compared with the FA groups after SS exposure on PND59. At the same time points, the percent area of SP nerve fibers in tracheal smooth muscle and the levels of NGF were significantly elevated. MCh dose–response curves for RL and Cdyn, SP nerve fiber density, and the level of NGF were not significantly changed in the PND21 exposure group after SS exposure on PND59. Conclusions These results suggest that a critical period of susceptibility to SS exposure exists in the prenatal and early postnatal period of development in mice that results in increased SP innervation, increased NGF levels in the airway, and enhanced MCh AHR later in life

    Prenatal and Early, but Not Late, Postnatal Exposure of Mice to Sidestream Tobacco Smoke Increases Airway Hyperresponsiveness Later in Life

    Get PDF
    Background Cigarette smoke exposure in utero and during early postnatal development increases the incidence of asthma and airway hyperresponsiveness (AHR) later in life, suggesting that a possible critical period of developmental sensitivity exists in the prenatal and early postnatal periods. Objective We investigated mechanisms of susceptibility during critical developmental periods to sidestream smoke (SS) exposure and evaluated the possible effects of SS on neural responses. Methods We exposed three different age groups of mice to either SS or filtered air (FA) for 10 consecutive days beginning on gestation day (GD) 7 by maternal exposure or beginning on postnatal day (PND) 2 or PND21 by direct inhalation. Lung function, airway substance P (SP) innervation, and nerve growth factor (NGF) levels in broncho alveolar lavage fluid were measured after a single SS exposure on PND59. Results Methacholine (MCh) dose response for lung resistance (RL) was significantly elevated, and dynamic pulmonary compliance (Cdyn) was significantly decreased, in the GD7 and PND2 SS exposure groups compared with the FA groups after SS exposure on PND59. At the same time points, the percent area of SP nerve fibers in tracheal smooth muscle and the levels of NGF were significantly elevated. MCh dose–response curves for RL and Cdyn, SP nerve fiber density, and the level of NGF were not significantly changed in the PND21 exposure group after SS exposure on PND59. Conclusions These results suggest that a critical period of susceptibility to SS exposure exists in the prenatal and early postnatal period of development in mice that results in increased SP innervation, increased NGF levels in the airway, and enhanced MCh AHR later in life
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