579 research outputs found
Nonlinear Dynamic Analysis, Volume II Final Report
Numerical methods and computer program for analyzing lateral plane vibration characteristics of simple structure possessing hysteresis dampin
Full-Scale Turbofan Engine Noise-Source Separation Using a Four-Signal Method
Contributions from the combustor to the overall propulsion noise of civilian transport aircraft are starting to become important due to turbofan design trends and expected advances in mitigation of other noise sources. During on-ground, static-engine acoustic tests, combustor noise is generally sub-dominant to other engine noise sources because of the absence of in-flight effects. Consequently, noise-source separation techniques are needed to extract combustor-noise information from the total noise signature in order to further progress. A novel four-signal source-separation method is applied to data from a static, full-scale engine test and compared to previous methods. The new method is, in a sense, a combination of two- and three-signal techniques and represents an attempt to alleviate some of the weaknesses of each of those approaches. This work is supported by the NASA Advanced Air Vehicles Program, Advanced Air Transport Technology Project, Aircraft Noise Reduction Subproject and the NASA Glenn Faculty Fellowship Program
Dialekt och skola. En orientering om förhållanden i Sverige
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Reaching the end of the line: Urinary tract infections
Urinary tract infections (UTIs) cause a substantial health care burden. UTIs (i) are most often caused by uropathogeni
Peculiarities of anharmonic lattice dynamics and thermodynamics of alkaline-earth metals
The calculations are performed for a broad range of the properties of Ca and
Sr in the fcc and bcc phases. A detailed information on the magnitude and
character of temperature dependence of anharmonic effects in the lattice
dynamics over the entire Brillouin zone (frequency shifts and phonon damping,
Gruneisen parameters) is given. A detailed comparison of the computational
results for the heat capacity and thermal expansion with the experimental data
is carried out; the theoretical results are in good agreement with the
experiment.Comment: 16 pages, 19 Postscript figures, Revte
Structural and chemical embrittlement of grain boundaries by impurities: a general theory and first principles calculations for copper
First principles calculations of the Sigma 5 (310)[001] symmetric tilt grain
boundary in Cu with Bi, Na, and Ag substitutional impurities provide evidence
that in the phenomenon of Bi embrittlement of Cu grain boundaries electronic
effects do not play a major role; on the contrary, the embrittlement is mostly
a structural or "size" effect. Na is predicted to be nearly as good an
embrittler as Bi, whereas Ag does not embrittle the boundary in agreement with
experiment. While we reject the prevailing view that "electronic" effects
(i.e., charge transfer) are responsible for embrittlement, we do not exclude
the role of chemistry. However numerical results show a striking equivalence
between the alkali metal Na and the semi metal Bi, small differences being
accounted for by their contrasting "size" and "softness" (defined here). In
order to separate structural and chemical effects unambiguously if not
uniquely, we model the embrittlement process by taking the system of grain
boundary and free surfaces through a sequence of precisely defined gedanken
processes; each of these representing a putative mechanism. We thereby identify
three mechanisms of embrittlement by substitutional impurities, two of which
survive in the case of embrittlement or cohesion enhancement by interstitials.
Two of the three are purely structural and the third contains both structural
and chemical elements that by their very nature cannot be further unravelled.
We are able to take the systems we study through each of these stages by
explicit computer simulations and assess the contribution of each to the nett
reduction in intergranular cohesion. The conclusion we reach is that
embrittlement by both Bi and Na is almost exclusively structural in origin;
that is, the embrittlement is a size effect.Comment: 13 pages, 5 figures; Accepted in Phys. Rev.
Mucosal infection rewires TNFÉ‘ signaling dynamics to skew susceptibility to recurrence
A mucosal infectious disease episode can render the host either more or less susceptible to recurrent infection, but the specific mechanisms that tip the balance remain unclear. We investigated this question in a mouse model of recurrent urinary tract infection and found that a prior bladder infection resulted in an earlier onset of tumor necrosis factor-alpha (TNFÉ‘)-mediated bladder inflammation upon subsequent bacterial challenge, relative to age-matched naive mice. However, the duration of TNFÉ‘ signaling activation differed according to whether the first infection was chronic (Sensitized) or self-limiting (Resolved). TNFÉ‘ depletion studies revealed that transient early-phase TNFÉ‘ signaling in Resolved mice promoted clearance of bladder-colonizing bacteria via rapid recruitment of neutrophils and subsequent exfoliation of infected bladder cells. In contrast, sustained TNFÉ‘ signaling in Sensitized mice prolonged damaging inflammation, worsening infection. This work reveals how TNFÉ‘ signaling dynamics can be rewired by a prior infection to shape diverse susceptibilities to future mucosal infections
Tomographic retrieval of water vapour and temperature around polar mesospheric clouds using Odin-SMR
Structure-function correlates of fibrinogen binding by Acinetobacter adhesins critical in catheter-associated urinary tract infections
Multidrug-resistan
Assessment techniques, database design and software facilities for thermodynamics and diffusion
The purpose of this article is to give a set of recommendations to producers of assessed thermodynamic data, who may be involved in either the critical evaluation of limited chemical systems or the creation and dissemination of larger thermodynamic databases. Also, it is hoped that reviewers and editors of scientific publications in this field will find some of the information useful. Good practice in the assessment process is essential, particularly as datasets from many different sources may be combined together into a single database. With this in mind, we highlight some problems that can arise during the assessment process and we propose a quality assurance procedure. It is worth mentioning at this point, that the provision of reliable assessed thermodynamic data relies heavily on the availability of high quality experimental information. The different software packages for thermodynamics and diffusion are described here only briefly
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