What doesn't kill you makes you stronger: Psychological trauma and its relationship to enhanced memory control.

Control processes engaged in halting the automatic retrieval of unwanted memories have been shown to reduce the later recallability of the targets of suppression. Like other cognitive skills that benefit from practice, we hypothesized that memory control is similarly experience dependent, such that individuals with greater real-life experience at stopping retrieval would exhibit better inhibitory control over unwanted memories. Across two experiments, we found that college students reporting a greater history of trauma exhibited more suppression-induced forgetting of both negative and neutral memories than did those in a matched group who had reported experiencing little to no trauma. The association was especially evident on a test of suppression-induced forgetting involving independent retrieval cues that are designed to better isolate the effects of inhibitory control on memory. Participants reporting more trauma demonstrated greater generalized forgetting of suppressed material. These findings raise the possibility that, given proper training, individuals can learn to better manage intrusive experiences, and are broadly consistent with the view that moderate adversity can foster resilience later in life. (PsycINFO Database Record (c) 2018 APA, all rights reserved)

Active Forgetting: Adaptation of Memory by Prefrontal Control.

Over the past century, psychologists have discussed whether forgetting might arise from active mechanisms that promote memory loss to achieve various functions, such as minimizing errors, facilitating learning, or regulating one's emotional state. The past decade has witnessed a great expansion in knowledge about the brain mechanisms underlying active forgetting in its varying forms. A core discovery concerns the role of the prefrontal cortex in exerting top-down control over mnemonic activity in the hippocampus and other brain structures, often via inhibitory control. New findings reveal that such processes not only induce forgetting of specific memories but also can suppress the operation of mnemonic processes more broadly, triggering windows of anterograde and retrograde amnesia in healthy people. Recent work extends active forgetting to nonhuman animals, presaging the development of a multilevel mechanistic account that spans the cognitive, systems, network, and even cellular levels. This work reveals how organisms adapt their memories to their cognitive and emotional goals and has implications for understanding vulnerability to psychiatric disorders

The Character Development Project Final Report

This report consists of three elements. The project outline offers an overview of the intervention and how it was implemented. Sections 3 to 6 include the Principal Investigators’ remarks (Professor Trevor Cooling), and the findings and recommendations of the researcher who designed the questionnaires and worked on data analysis (Dr Sabina Hulbert), and the researchers who undertook school visits and have worked on deriving qualitative case study data from the visits as well as school portfolios (Miss Caroline Thomas and Dr Peter Gregory). Finally, we include a summary of the evaluation report

Viewing art on a tablet computer: a wellbeing intervention for people with dementia and their caregivers

Background: Art-based interventions have been shown to be beneficial for the wellbeing of people with dementia and their caregivers. This paper explored whether such interventions can be delivered via a touchscreen tablet device displaying art images. Methods: Twelve pairs of volunteers with dementia and informal caregivers were recruited. A quasi-experimental mixed-methods within-subjects study evaluated the wellbeing impacts of art viewing using visual analogue scales and explored participant experiences with thematic analysis. Findings: Quantitative results showed a significant effect for change in composite wellbeing from session one to session five. Wellbeing subdomains showed impact on wellbeing, which generally increased with number of sessions. Qualitative findings included changes in cognition, behaviour, mood and relationships. These changes tended to be viewed positively. Conclusions: The results suggest touchscreen-based art interventions could yield wellbeing benefits for this population. A larger-scale controlled study would help to determine whether wider dementia care practice implications can be drawn

An experimental and theoretical investigation of plane-stress fracture of 2024-T351 aluminum alloy

Plane-stress fracture behavior of precracked aluminum alloy

Body temperatures of modern and extinct vertebrates from ^(13)C-^(18)O bond abundances in bioapatite

The stable isotope compositions of biologically precipitated apatite in bone, teeth, and scales are widely used to obtain information on the diet, behavior, and physiology of extinct organisms and to reconstruct past climate. Here we report the application of a new type of geochemical measurement to bioapatite, a “clumped-isotope” paleothermometer, based on the thermodynamically driven preference for ^(13)C and ^(18)O to bond with each other within carbonate ions in the bioapatite crystal lattice. This effect is dependent on temperature but, unlike conventional stable isotope paleothermometers, is independent from the isotopic composition of water from which the mineral formed. We show that the abundance of ^(13)C-^(18)O bonds in the carbonate component of tooth bioapatite from modern specimens decreases with increasing body temperature of the animal, following a relationship between isotope “clumping” and temperature that is statistically indistinguishable from inorganic calcite. This result is in agreement with a theoretical model of isotopic ordering in carbonate ion groups in apatite and calcite. This thermometer constrains body temperatures of bioapatite-producing organisms with an accuracy of 1–2 °C. Analyses of fossilized tooth enamel of both Pleistocene and Miocene age yielded temperatures within error of those derived from similar modern taxa. Clumped-isotope analysis of bioapatite represents a new approach in the study of the thermophysiology of extinct species, allowing the first direct measurement of their body temperatures. It will also open new avenues in the study of paleoclimate, as the measurement of clumped isotopes in phosphorites and fossils has the potential to reconstruct environmental temperatures

Parallel Regulation of Memory and Emotion Supports the Suppression of Intrusive Memories.

Intrusive memories often take the form of distressing images that emerge into a person's awareness, unbidden. A fundamental goal of clinical neuroscience is to understand the mechanisms allowing people to control these memory intrusions and reduce their emotional impact. Mnemonic control engages a right frontoparietal network that interrupts episodic retrieval by modulating hippocampal activity; less is known, however, about how this mechanism contributes to affect regulation. Here we report evidence in humans (males and females) that stopping episodic retrieval to suppress an unpleasant image triggers parallel inhibition of mnemonic and emotional content. Using fMRI, we found that regulation of both mnemonic and emotional content was driven by a shared frontoparietal inhibitory network and was predicted by a common profile of medial temporal lobe downregulation involving the anterior hippocampus and the amygdala. Critically, effective connectivity analysis confirmed that reduced amygdala activity was not merely an indirect consequence of hippocampal suppression; rather, both the hippocampus and the amygdala were targeted by a top-down inhibitory control signal originating from the dorsolateral prefrontal cortex. This negative coupling was greater when unwanted memories intruded into awareness and needed to be purged. Together, these findings support the broad principle that retrieval suppression is achieved by regulating hippocampal processes in tandem with domain-specific brain regions involved in reinstating specific content, in an activity-dependent fashion.SIGNIFICANCE STATEMENT Upsetting events sometimes trigger intrusive images that cause distress and that may contribute to psychiatric disorders. People often respond to intrusions by suppressing their retrieval, excluding them from awareness. Here we examined whether suppressing aversive images might also alter emotional responses to them, and the mechanisms underlying such changes. We found that the better people were at suppressing intrusions, the more it reduced their emotional responses to suppressed images. These dual effects on memory and emotion originated from a common right prefrontal cortical mechanism that downregulated the hippocampus and amygdala in parallel. Thus, suppressing intrusions affected emotional content. Importantly, participants who did not suppress intrusions well showed increased negative affect, suggesting that suppression deficits render people vulnerable to psychiatric disorders

User guide for the GeoScour GB V1 dataset

This report describes the BGS GeoScour data product. The methods used to create the component datasets have been critically assessed and its fitness for purpose determined by specialists in BGS. GeoScour looks specifically and only at the geological factors that influence scour and does not consider any hydraulic or hydrodynamic factors. This document outlines the background to why the dataset was created, its potential uses and gives a brief description of the data layers. Technical information regarding the GIS and how the data was created is described and advice is provided on using the dataset