995 research outputs found
Body mass index and extent of MRI-detected inflammation: opposite effects in rheumatoid arthritis versus other arthritides and asymptomatic persons
Imaging- and therapeutic targets in neoplastic and musculoskeletal inflammatory diseas
Anomalous Spin Dynamics observed by High Frequency ESR in Honeycomb Lattice Antiferromagnet InCu2/3V1/3O3
High-frequency ESR results on the S=1/2 Heisenberg hexagonal antiferromagnet
InCu2/3V1/3O3 are reported. This compound appears to be a rare model substance
for the honeycomb lattice antiferromagnet with very weak interlayer couplings.
The high-temperature magnetic susceptibility can be interpreted by the S=1/2
honeycomb lattice antiferromagnet, and it shows a magnetic-order-like anomaly
at TN=38 K. Although, the resonance field of our high-frequency ESR shows the
typical behavior of the antiferromagnetic resonance, the linewidth of our
high-frequency ESR continues to increase below TN, while it tends to decrease
as the temperature in a conventional three-dimensional antiferromagnet
decreases. In general, a honeycomb lattice antiferromagnet is expected to show
a simple antiferromagnetic order similar to that of a square lattice
antiferromagnet theoretically because both antiferromagnets are bipartite
lattices. However, we suggest that the observed anomalous spin dynamics below
TN is the peculiar feature of the honeycomb lattice antiferromagnet that is not
observed in the square lattice antiferromagnet.Comment: 5 pages, 5 figure
Predicting risk for radiographic damage in rheumatoid arthritis:comparative analysis of the multi-biomarker disease activity score and conventional measures of disease activity in multiple studies
Pathophysiology and treatment of rheumatic disease
Study trip as means of expanded learning
This article explores the study trip as an interconnected activity of work and play, constituting an extended means of teaching design studio in spatial design related disciplines. This study analyses the case of a cohort of about 200 students involved in a joint project in three cities, Athens, Tokyo and London, where groups were challenged with a common project brief. The students conducted empirical studies of the cities through play and enjoyment. The case study provides evidence of the benefits and issues emerging in this particular teaching and learning method of project-based and field work research in spatial design
Phase diagram of a Heisenberg spin-Peierls model with quantum phonons
Using a new version of the density-matrix renormalization group we determine
the phase diagram of a model of an antiferromagnetic Heisenberg spin chain
where the spins interact with quantum phonons. A quantum phase transition from
a gapless spin-fluid state to a gapped dimerized phase occurs at a non-zero
value of the spin-phonon coupling. The transition is in the same universality
class as that of a frustrated spin chain, which the model maps to in the
anti-adiabatic limit. We argue that realistic modeling of known spin-Peierls
materials should include the effects of quantum phonons.Comment: RevTeX, 5 pages, 3 eps figures included using epsf. Improved theories
in adiabatic and non-adiabatic regimes give better agreement with DMRG. This
version accepted in Physical Review Letter
Association of the 6q23 region with the rate of joint destruction in rheumatoid arthritis
BACKGROUND: /st> Two novel genetic polymorphisms on chromosome 6q23 are associated with susceptibility to rheumatoid arthritis (RA). Both polymorphisms (rs6920220 and rs10499194) reside in a region close to the gene encoding tumour necrosis factor alpha-induced protein 3 (TNFAIP3). TNFAIP3 is a negative regulator of NF-kappaB and is involved in inhibiting TNF-receptor-mediated signalling effects. Interestingly, the initial associations were detected in patients with longstanding RA. However, no association was found for rs10499194 in a Swedish cohort with early arthritis. This might be caused by over-representation of patients with severe disease in cohorts with longstanding RA. OBJECTIVE: /st> To analyse the effect of the 6q23 region on the rate of joint destruction. METHODS: /st> Five single nucleotide polymorphisms in 6q23 were genotyped in 324 Dutch patients with early RA. Genotypes were correlated with progression of radiographic joint damage for a follow-up time of 5 years. RESULTS: /st> Two polymorphisms (rs675520 and rs9376293) were associated with severity of radiographic joint damage in patients positive for anti-citrullinated protein/peptide antibodies (ACPA). Importantly, the effects were present after correction for confounding factors such as secular trends in treatment. CONCLUSIONS: /st> These data associate the 6q23 region with the rate of joint destruction in ACPA+ RA.Pathophysiology and treatment of rheumatic disease
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Everyday life and locative play: an exploration of Foursquare and playful engagements with space and place
Foursquare is a location-based social network (LBSN) that combines gaming elements with features conventionally associated with social networking sites (SNSs). Following two qualitative studies, this article sets out to explore what impact this overlaying of physical environments with play has on everyday life and experiences of space and place. Drawing on early understandings of play, alongside the flâneur and ‘phoneur’ as respective methods for conceptualizing play in the context of mobility and urbanity, this article examines whether the suggested division between play and ordinary life is challenged by Foursquare, and if so, how this reframing of play is experienced. Second, this article investigates what effect this LBSN has on mobility choices and spatial relationships. Finally, the novel concept of the ‘phoneur’ is posited as a way of understanding how pervasive play through LBSNs acts as a mediating influence on the experience of space and place
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