73 research outputs found
The cytosolic DnaJ-like protein Djp1p is involved specifically in peroxisomal protein import
The Saccharomyces cerevisiae DJP1 gene encodes
a cytosolic protein homologous to Escherichia coli
DnaJ. DnaJ homologues act in conjunction with molecular
chaperones of the Hsp70 protein family in a variety
of cellular processes. Cells with a DJP1 gene deletion
are viable and exhibit a novel phenotype among cytosolic
J-protein mutants in that they have a specific impairment
of only one organelle, the peroxisome. The phenotype
was also unique among peroxisome assembly
mutants: peroxisomal matrix proteins were mislocalized
to the cytoplasm to a varying extent, and peroxisomal
structures failed to grow to full size and exhibited a
broad range of buoyant densities. Import of marker
proteins for the endoplasmic reticulum, nucleus, and
mitochondria was normal. Furthermore, the metabolic
adaptation to a change in carbon source, a complex
multistep process, was unaffected in a DJP1 gene deletion
mutant. We conclude that Djp1p is specifically required
for peroxisomal protein import
Wellenlaengendurchstimmbare cw- und Puls-Halbleiterlaserquellen mit externen Glasfaserkavitaeten fuer die Gasanalytik
Available from TIB Hannover: DtF QN1(92,43) / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekSIGLEBundesministerium fuer Bildung, Wissenschaft, Forschung und Technologie, Bonn (Germany)DEGerman
Novel design for a mode-hop free tunable single mode external fiber cavity semiconductor laser
Available from TIB Hannover: DtF QN1(92,44) / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekSIGLEBundesministerium fuer Bildung, Wissenschaft, Forschung und Technologie, Bonn (Germany)DEGerman
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