7 research outputs found
Genetic mechanisms of critical illness in COVID-19.
- Author
- A A Roger Thompson
- A Abraheem
- A Agasou
- A Ahmed
- A Ali
- A Allan
- A Altabaibeh
- A Alvaro
- A Aspinwall
- A Ayers
- A Bamford
- A Barron
- A Bashyal
- A Bellini
- A Bociek
- A Botello
- A Bowes
- A Brady
- A Brayne
- A Brown
- A Brown
- A Butler
- A Campbell
- A Carter
- A Collins
- A Cowley
- A Cowton
- A Cowton
- A Cox
- A Crew
- A Dance
- A Daniel
- A Daniels
- A Dela Rosa
- A Drummond
- A Durie
- A E Heron
- A Easthope
- A Easthope
- A Evans
- A Fofano
- A Gales
- A Ganesan
- A Gardner
- A Garg
- A Gherman
- A Gordon
- A Gratrix
- A Gulati
- A Gupta
- A Haigh
- A Haldeos
- A Harrison
- A Harvey
- A Hayes
- A Higham
- A Higham
- A Hilldrith
- A Holden
- A Hormis
- A Hutcheon
- A Javaid
- A Joseph
- A Kaliappan
- A Katary
- A Kay
- A Kayani
- A Kent
- A Kirkby
- A Knight
- A Kubisz-Pudelko
- A Kuravi
- A Lewis
- A Loveridge
- A Lyle
- A Mayer
- A McAlpine
- A McCarthy
- A McGregor
- A McGregor
- A Meikle
- A Mitchell
- A Mitra
- A Morris
- A Morrison
- A Naranjo
- A Nicholson
- A Nicholson
- A Nilsson
- A Noakes
- A Patel
- A Pickard
- A Poole
- A Price
- A Puxty
- A Quinn
- A Quinn
- A Raithatha
- A Rattray
- A Reddy
- A Reed
- A Reyes
- A Rose
- A Rose
- A Rostron
- A Roy
- A Roynon-Reed
- A S Raj
- A Salberg
- A Sanderson
- A Serrano-Ruiz
- A Solesbury
- A Sukha
- A Swain
- A Tariq
- A Thomas
- A Thomas
- A Todd
- A Tomas
- A Tridente
- A Tucci
- A Turnbull
- A Uriel
- A Ustianowski
- A Vochin
- A Vuylsteke
- A Waite
- A Walden
- A Whileman
- A Wilkinson
- A Williams
- A Williams
- A Wilson
- A Zak
- A Zaki
- Achille Iolascon
- Adam Auton
- Adam Brown
- Agnese Verzuri
- Agostino Ognibene
- Agostino Riva
- Ailsa Golightly
- Alan Maclean
- Alessandra
- Alessandra Stella
- Alessandra Vergori
- Alessia Giorli
- Alexander J Mentzer
- Alice Donati
- Alison M Meynert
- Alistair Nichol
- Ana da Silva Filipe
- Andrea Antinori
- Andrea Cossarizza
- Andrea Ganna
- Andrea Tommasi
- Andrew Rambaut
- Andrew Stenhouse
- Andy Law
- Anjali J Shastri
- Anna Canaccini
- Anna Maria Pinto
- Annarita Giliberti
- Annemarie B Docherty
- Antonella D'Arminio Monforte
- Antonia Ying Wai Ho
- Antonio Di Biagio
- Antony Symons
- Arianna Emiliozzi
- Arianna Gabrieli
- Audrey Coutts
- B Anwar
- B Attwood
- B Baines
- B Blackledge
- B Borislavova
- B Chandler
- B Charles
- B Creagh-Brown
- B David
- B Deacon
- B Deacon
- B Digby
- B Faulkner
- B Fuller
- B Gumbrill
- B Gurung
- B Hadebe
- B Hairsine
- B Hopkins
- B Johnston
- B Lenagh
- B Masunda
- B Ogg
- B Patel
- B Player
- B Purewal
- B Scholefield
- B Shelley
- B Sloan
- B Thomas
- B Wadams
- B Welsh
- B Wilkinson
- B Winter-Goodwin
- B Yates
- Baillie J Kenneth
- Barbara Rossetti
- Beale Rupert
- Beatrice Alex
- Benjamin Bach
- Bretherick Andrew D
- Bruno Frediani
- C Adams
- C Ahmed
- C Almaden-Boyle
- C Ashbrook-Raby
- C Basikolo
- C Battle
- C Beazley
- C Beith
- C Borra
- C Brandwood
- C Brantwood
- C Burnett
- C Castro Delgado
- C Clark
- C Clulow
- C Collins
- C Cruz
- C Davis
- C Demetriou
- C Dennis
- C Dexter
- C Downes
- C Dunmore
- C Eastgate
- C Eckbad
- C Finch
- C Gibson
- C Gorman
- C Hays
- C Hewitt
- C Holl
- C Howcroft
- C Humphrey
- C Jackson
- C Jardine
- C Jennings
- C Jones
- C Kaye
- C Lynch
- C Lyons
- C McCulloch
- C McParland
- C McParland
- C Murphy
- C Parmar
- C Pawley
- C Phillips
- C Phillips
- C Pothecary
- C Pothecary
- C Prendergast
- C Price
- C Rishton
- C Sell
- C Shovelton
- C Sicat
- C Stuart
- C Summers
- C Swan
- C Thompson
- C Thorpe
- C Tibke
- C Tierney
- C Vigurs
- C Wells
- C Whitton
- C Whyte
- C Wrey Brown
- Cameron J Fairfield
- Carmelo Piscopo
- Carmen Marciano
- Caroline Abernathy
- Carrol Gamble
- Caterina Lo Rizzo
- Catherine A Shaw
- Catherine H Weldon
- Caulfield Mark
- Ceilia Boz
- Cesira Nencioni
- Chelsea Ye
- Chiara Fallerini
- Chiara Gabbi
- Chiara Spertilli
- Chloe Donohue
- Chris Ponting
- Christoper A Green
- Cinthia E Jannes
- Clare Jackson
- Clohisey Sara
- Cristina Mussini
- D Antcliffe
- D Bakthavatsalam
- D Banach
- D Baptista
- D Bell
- D Branney
- D Brealey
- D Brealey
- D Butcher
- D Butcher
- D Childs
- D Clarke
- D Collier
- D Collier
- D Cristiano
- D Dawson
- D Donaldson
- D Duffin
- D Fottrell-Gould
- D Golden
- D Griffin
- D Hamilton
- D Hawcutt
- D Hope
- D Horner
- D Kallon
- D Kaye
- D Kelly
- D Loader
- D Lomas
- D Martin
- D McGlynn
- D McLaughlanv
- D Melia
- D Menzies
- D Mullan
- D Pogson
- D Potla
- D Potoczna
- D Purohit
- D Raynard
- D Salutous
- D Salutous
- D Scaletta
- D Shaw
- D Skinner
- D Smyth
- D Strachan
- D Tetla
- D Thornton
- D Trodd
- D Vedage
- D Walker
- D Warren
- D Williams
- D Wood
- D Wright
- Daniela Francisci
- Daniella Coker
- Danilo Tacconi
- David A van Heel
- David Bennet
- David L Robertson
- David Stuart
- Dawn Law
- Debby Bogaert
- Derek Murphy
- Domenico A Coviello
- E Abaleke
- E Allan
- E Anastasescu
- E Andrews
- E Apetri
- E B Jude
- E Beech
- E Beranova
- E Bevan
- E Black
- E Brinkworth
- E Collins
- E Combes
- E Davies
- E Dobson
- E Dooks
- E Fisher
- E Gendall
- E Goff
- E Goodwin
- E Gordon
- E Heeney
- E Horsley
- E Hughes
- E Johnson
- E Knights
- E Lee
- E London
- E Maccacari
- E Massey
- E McKenna
- E Meadows
- E Moncur
- E Morino
- E Mwaura
- E Peasgood
- E Perkins
- E Radford
- E Raith
- E Raith
- E Salciute
- E Smith
- E Smithson
- E Stoddard
- E Stones
- E Thomas
- E Tilney
- E Timlick
- E Treus Gude
- E Virgilio
- E Watson
- E Wilby
- Edoardo Conticini
- Egle Saviciute
- Elena Bargagli
- Elena Desanctis
- Elisa Benetti
- Elisa Frullanti
- Elisabetta Menatti
- Elisabetta Schiaroli
- Ellie Mcmaster
- Emma C Thomson
- Emmanuelle Marques
- Enrico Martinelli
- Esther Duncan
- Esther Merlini
- Ewen M Harrison
- F Anderson
- F Auld
- F Bibi
- F Davies
- F Farquhar
- F Fisher
- F Hurford
- F Kibutu
- F McNeela
- F Moore
- F Nasir
- F Trim
- F Wakinshaw
- F Williams
- Fabio Lena
- Fawkes Angie
- Federico Anedda
- Federico Franchi
- Ferdinando Giannattasio
- Filip Taneski
- Filippo Aucella
- Filippo Biscarini
- Floriana Valentino
- Fourman Max Head
- Francesca Andretta
- Francesca Fava
- Francesca Gatti
- Francesca Mari
- Francesca Montagnani
- Francesco Castelli
- Francesco Raimondi
- Furniss James
- G Andrew
- G Arbane
- G Bell
- G Bercades
- G Croston
- G Debreceni
- G Durrant
- G Hambrook
- G Hobden
- G Houston
- G Hughes
- G Jones
- G Lubimbi
- G Maloney
- G Martir
- G Millen
- G Mills
- G O'Connor
- G Padden
- G Randell
- G Sadera
- G Seddon
- G Sera Howe
- G Sloane
- G Subramanian
- G Tsinaslanidis
- G Turner
- G Watson
- G Wray
- Gabriella Coiro
- Gabriella Doddato
- Gail Carson
- Gardar Sveinbjornsson
- Gary Leeming
- Genni Spargi
- Georgios Pollakis
- Giacomo Zanelli
- Gian Piero Caldarelli
- Giancarlo Bosio
- Giuseppe Fiorentino
- Giuseppe Merla
- Gountouna Elvina
- Graham S Cooke
- Griffiths Fiona
- Grimes Graeme
- H Bancroft
- H Bates
- H Belfield
- H Blackman
- H Blakemore
- H Brooke
- H Button
- H Coles
- H Curgenven
- H Filipe
- H Fox
- H Golding
- H Hill
- H Holcombe
- H Houlden
- H Jeffrey
- H Kent
- H Langton
- H McGuinness
- H Meghari
- H Millward
- H Moore
- H Parker
- H Pearson
- H Prady
- H Quinn
- H Rangarajan
- H Rehman
- H Reschreiter
- H Riley
- H Sainsbury
- H Savill
- H Sturgeon
- H T-Michael
- H Tench
- H Tiveran
- H Turner
- H Whittle
- H Willis
- H Wood
- Haley Chris
- Hanning Mal
- Harrison David
- Hayley Hardwick
- Hayward Caroline
- Helen Szoor-McElhinney
- Hinds Charles
- Ho Antonia
- Horby Peter
- I Ali Mohamed Ali
- I Balagosa
- I Birkinshaw
- I Burn
- I Chadbourn
- I D Clement
- I Edmond
- I Frost
- I Hass
- I Hussain
- I Lancoma-Malcolm
- I Leadbitter
- I Nagra
- I Otahal
- I Otahal
- I Turner-Bone
- I Welters
- I White
- I Wynter
- Ilaria Meloni
- Immacolata Andolfo
- Isabella Zanella
- J Allan
- J Barker
- J Bewley
- J Biddle
- J Birch
- J Birch
- J Bradley-Potts
- J Brown
- J Bryant
- J Butler
- J Camsooksai
- J Carter
- J Caterson
- J Cebrian Suarez
- J Cockerill-Taylor
- J Cole
- J Colley
- J Cooper
- J Cupitt
- J Cuttler
- J Daglish
- J Dasgin
- J Dawson
- J Dearden
- J Deery
- J Donnachie
- J Dykes
- J Easton
- J Egan
- J Fernandez Roman
- J Finn
- J Fletcher
- J Frankham
- J Gaylard
- J Gill
- J Godden
- J Goodsell
- J Gregory
- J Greig
- J Gurasashvili
- J Hardy
- J Harris
- J Hatton
- J Hawes
- J Highgate
- J Hornsby
- J Hulme
- J Hunt
- J Hutter
- J Ingham
- J Jones
- J Jones
- J K Baillie
- J Kassam
- J Kenneth Baillie
- J Kenneth Baillie
- J Keshet-Price
- J Liew
- J Little
- J Mallinson
- J Martin
- J Matthews
- J McCormick
- J Medhora
- J Melville
- J Moreno Cuesta
- J Morgan
- J Naisbitt
- J Norris
- J North
- J Parkin
- J Pendlebury
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- J Perry
- J Pheby
- J Philbin
- J Pinnell
- J Queiroz
- J Radhakrishnan
- J Reid
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- J Ritzema
- J Ruddy
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- J Scriven
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- J Shiel
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- J Taylor
- J Tebbutt
- J Texeira
- J Thomas
- J Thrush
- J Tomlinson
- J Valentine
- J Whiteside
- J Wilkins
- J Willson
- J Zamikula
- Jake Dunning
- Jane Weaver
- Janet Harrison
- Janet T Scott
- Janie F Shelton
- Jen Meikle
- Jo Dalton
- Johnny Millar
- Jorge Esparza-Gordillo
- Jose E Krieger
- Julian A Hiscox
- K Archer
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- K Dent
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- K Elston
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- K Fernandes
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- K Gilbert
- K Golder
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- K Hanson
- K Hanson
- K Hard
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- K Hayes
- K Holding
- K Holdroyd
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- K Hugill
- K Inweregbu
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- K Karthik
- K King
- K Knowles
- K Lang
- K Liyanage
- K Manso
- K Netherton
- K Postlethwaite
- K Potts
- K Prager
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- K Pritchard
- K Puxty
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- K Rooney
- K Sellick
- K Shuker
- K Simpson
- K Simpson
- K Slevin
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- K Stammers
- K Stroud
- K Sweet
- K Tatham
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- K White
- K Williams
- K Xavier
- Katarzyna Hafezi
- Keating Sean
- Kenneth A Mclean
- Kirstie Morrice
- Klaric Lucija
- Klenerman Paul
- Knight Julian
- Kousathanas Athanasios
- L Abel
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- L Allen
- L Armstrong
- L Barclay
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- L Gurr
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- L Hudig
- L Keating
- L Kittridge
- L Lankester
- L Lennon
- L Lim
- L Ma
- L Marshall
- L Matupe
- L McMorrow
- L McQuillan
- L Mew
- L Mostoles
- L Mwaura
- L Newey
- L O'Brien
- L O'Malley
- L O'Neill
- L Ortiz-Ruiz de Gordoa
- L Ortiz-Ruiz de Gordoa
- L Park
- L Pippard
- L Prentice
- L Rad
- L Ramos
- L Riddles
- L Roche
- L Roche
- L Rooney
- L Rosaroso
- L Shaw
- L Smith
- L Stevenson
- L Symon
- L Thomis
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- L Thrasyvoulou
- L Ting
- L Tonks
- L Turner
- L van Koutrik
- L Wilcox
- L Wild
- L Wilding
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- L Wren
- L Zitter
- Lance C W Turtle
- Laura Bergantini
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- Laura Marsh
- Laura Merson
- Law Andrew
- Leonardo Croci
- Lia Crotti
- Ling Lowell
- Lisa Norman
- Lorenzo Salerni
- Lorna Donnelly
- Louise Cullum
- Louise Macgillivray
- Louise Sigfrid
- Luca Cantarini
- Luca Guidelli
- Luca Masucci
- Luisa Tavecchia
- M Abdelrazik
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- M Bates
- M Bellamy
- M Birt
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- M Bokhari
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- M Bromley
- M Bruce
- M Brunton
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- M Callaghan
- M Carmody
- M Carnahan
- M Casey
- M Caswell
- M Chablani
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- M Clark
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- M Croft
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- M Davey
- M Davies
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- Maaike Swets
- Mahdad Noursadeghi
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- Marco Castori
- Marco Feri
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- Marco Mandalà
- Marco Sita
- Margherita Baldassarri
- Mari E K Niemi
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- Meera Chand
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- Michelle Girvan
- Millar Jonathan
- Mirella Bruttini
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- S Gopal
- S Greer
- S Gurung Rai
- S Henderson
- S Hierons
- S Hope
- S Humphreys
- S Hussain
- S Jenkins
- S Jhanji
- S Jones
- S Jose
- S Joseph
- S Kaul
- S Keenan
- S Keith
- S Kennedy-Hay
- S Kimber
- S Kumar
- S Laha
- S Latham
- S Leaver
- S Lee
- S Leggett
- S MacFadyen
- S Manna
- S Marriott
- S Masuko
- S McIvor
- S McKechnie
- S Melling
- S Mellor
- S Mepham
- S Metherell
- S Mitchard
- S Mohamed Ally
- S Monnery
- S Moore
- S Morrison
- S Moultrie
- S Mtuwa
- S Mulla
- S Munt
- S Murdoch
- S O'Sullivan
- S Packham
- S Patch
- S Pearson
- S Pitts
- S Preston
- S Purvis
- S Quaid
- S Ray
- S Roche
- S Rose
- S Rundell
- S Salmi
- S Sathe
- S Selvanayagam
- S Shelton
- S Shepardson
- S Siddiqui
- S Smuts
- S Sousa Arias
- S Spencer
- S Srikaran
- S Stone
- S Swann
- S Tilbey
- S Turki
- S Turney
- S Twiss
- S Wadd
- S Whiteley
- S Williams
- S Wood
- S Yussuf
- Sabino Scolletta
- Samreen Ijaz
- Sandro Mancarella
- Sandro Panese
- Sara Amitrano
- Sara McDonald
- Sarah Law
- Sarah McCafferty
- Saverio Giuseppe Parisi
- Saye Khoo
- Scott Richard
- Semple Malcolm G
- Serafina Valente
- Serena Ludovisi
- Sergio Daga
- Seán Keating
- Shankar-Hari Manu
- Shen Xia
- Shih Barbara
- Shiranee Sriskandan
- Shona C Moore
- Silvia Cappelli
- Simona Marcantonio
- Simone Furini
- Sophie Halpin
- Sophie Venturelli
- Stefania Mantovani
- Stefano Baratti
- Stefano Ceri
- Stefano Rusconi
- Stella Aslibekyan
- Stephanie Roberts
- Stephen R Knight
- Summers Charlotte
- Susanna Croci
- Susanna Guerrini
- T Anderson
- T Arden
- T Baird
- T Behan
- T Bemand
- T Cosier
- T Coventry
- T Duncan
- T Felton
- T Geary
- T Hazleton
- T Joefield
- T Kannan
- T Lawton
- T Marsden
- T Martin
- T McHugh
- T Newman
- T Nortcliffe
- T O Jones
- T Pogreban
- T Rees
- T Samakomva
- T Smith
- T Smith
- T Szakmany
- T Varghes
- T Williams
- T Wood
- Tammy Gilchrist
- Tenesa Albert
- Teresa Filshtein-Sonmez
- Thomas M Drake
- Thushan de Silva
- Tim Walsh
- Tom Fletcher
- Tom Solomon
- Tony Wackett
- Trevor Paterson
- Tullio Trotta
- Turtle Lance
- U Poultney
- V Amin
- V Anumakonda
- V Bastion
- V Cannons
- V Crickmore
- V Gopal
- V Irvine
- V Kasipandian
- V Krishnamurthy
- V Lake
- V Linnett
- V Martinson
- V Nagarajan
- V Page
- V Parris
- V Parris
- V Pristopan
- V Ratnam
- V Rivers
- V Sarathy
- V Thomas
- V Thwaites
- V Tuckey
- V Turner
- V Wagstaff
- V Waugh
- Valentina Anemoli
- Vanessa Sancho-Shimizu
- Victoria Shaw
- Vitart Veronique
- W Harrison
- W Khaliq
- W Khaliq
- W McCormick
- W Woodyatt
- Walker Susan
- Walsh Timothy
- Wang Bo
- Wei Shen Lim
- Wendy S Barclay
- William A Paxton
- William Greenhalf
- Wilson James F
- Wrobel Nicola
- Wu Yang
- X Qiu
- Y Baird
- Y Choudhury
- Y Hussain
- Y Jackson
- Y Thirlwall
- Yang Jian
- Yang Zhijian
- Z Alldis
- Z Belagodu
- Z Bradshaw
- Z Coton
- Z Daly
- Z Farzad
- Z Fernandez
- Z Garland
- Z Maqsood
- Z Omar
- Z Prime
- Z Scott
- Zechner Marie
- Zhai Ranran
- Zheng Chenqing
- Publication venue
- Nature
- Publication date
- 01/01/2020
- Field of study
Host-mediated lung inflammation is present1, and drives mortality2, in the critical illness caused by coronavirus disease 2019 (COVID-19). Host genetic variants associated with critical illness may identify mechanistic targets for therapeutic development3. Here we report the results of the GenOMICC (Genetics Of Mortality In Critical Care) genome-wide association study in 2,244 critically ill patients with COVID-19 from 208 UK intensive care units. We have identified and replicated the following new genome-wide significant associations: on chromosome 12q24.13 (rs10735079, P = 1.65 × 10-8) in a gene cluster that encodes antiviral restriction enzyme activators (OAS1, OAS2 and OAS3); on chromosome 19p13.2 (rs74956615, P = 2.3 × 10-8) near the gene that encodes tyrosine kinase 2 (TYK2); on chromosome 19p13.3 (rs2109069, P = 3.98 × 10-12) within the gene that encodes dipeptidyl peptidase 9 (DPP9); and on chromosome 21q22.1 (rs2236757, P = 4.99 × 10-8) in the interferon receptor gene IFNAR2. We identified potential targets for repurposing of licensed medications: using Mendelian randomization, we found evidence that low expression of IFNAR2, or high expression of TYK2, are associated with life-threatening disease; and transcriptome-wide association in lung tissue revealed that high expression of the monocyte-macrophage chemotactic receptor CCR2 is associated with severe COVID-19. Our results identify robust genetic signals relating to key host antiviral defence mechanisms and mediators of inflammatory organ damage in COVID-19. Both mechanisms may be amenable to targeted treatment with existing drugs. However, large-scale randomized clinical trials will be essential before any change to clinical practice
A prenylated dsRNA sensor protects against severe COVID-19
- Author
- Adeniji Kayode
- Agranoff Daniel
- Agwuh Ken
- Ahmed Katie A.
- Ail Dhiraj
- Aldera Erin L.
- Alegria Ana
- Alex Beatrice
- Allan Jay
- Allen Sam
- Andrikopoulos Petros
- Angus Brian
- Armstrong Jane A.
- Ashish Abdul
- Ashworth Milton
- Asiimwe Innocent G.
- Atkinson Dougal
- Bach Benjamin
- Baillie J. Kenneth
- Baillie J. Kenneth
- Bakshi Siddharth
- Barclay Wendy S.
- Bari Shahedal
- Barlow Gavin
- Barlow Samantha L.
- Barnass Stella
- Barrett Nicholas
- Bassford Christopher
- Basude Sneha
- Baxter David
- Beadsworth Michael
- Bernatoniene Jolanta
- Berridge John
- Berry Colin
- Best Nicola
- Bogaert Debby
- Booth Laura
- Bothma Pieter
- Brennan Benjamin
- Brittain-Long Robin
- Bullock Katie
- Bulteel Naomi
- Burden Tom
- Burtenshaw Andrew
- Cameron-Ruiz Natalia
- Carlucci Nicola
- Carracedo Alejandra Doce
- Carson Gail
- Caruth Vikki
- Cass Emily
- Castello Alfredo
- Catterall Benjamin W. A.
- Chadwick David
- Chadwick David
- Chambler Duncan
- Chand Meera
- Chechi Kanta
- Chee Nigel
- Child Jenny
- Chukkambotla Srikanth
- Clark Jordan J.
- Clark Tom
- Clarke Emily A.
- Clohisey Sara
- Clohisey Sara
- Cole Sarah
- Cole Sarah
- Collini Paul
- Connor Marie
- Cooke Graham S.
- Cooper Louise
- Cosgrove Catherine
- Cox Helen
- Crozier Thomas W. M.
- Cupitt Jason
- Cutino-Moguel Maria-Teresa
- Da Silva Filho Joao Luiz
- da Silva Filipe Ana
- Dalton Jo
- Dark Paul
- Davies Emma L.
- Davis Christopher
- Davis Ilan
- Dawson Chris
- de Lima Ferreira Luiz Carlos
- de Silva Thushan
- Dervisevic Samir
- Dincarslan Oslem
- Docherty Annemarie B.
- Donegan Cara
- Donnison Phil
- Donohue Chloe
- dos Santos Correia Gonçalo
- Douthwaite Sam
- Drake Thomas M.
- Drummond Andrew
- Dumas Marc-Emmanuel
- Dunn Chris
- Dunning Jake
- DuRand Ingrid
- Dushianthan Ahilanadan
- Dyer Philip
- Dyer Tristan
- Elliott Angela
- Evans Anthony
- Evans Cariad
- Eziefula Chi
- Fairfield Cameron J.
- Fawkes Angie
- Fegan Chrisopher
- Finch Lorna
- Finn Adam
- Fisher Lewis W. S.
- Flaherty Lisa
- Fletcher Tom
- Foster Terry
- Freire Santana Monique
- Fullerton Duncan
- Gamble Carrol
- Garcia-Dorival Isabel
- Garg Atul
- Garg Sanjeev
- Girvan Michelle
- Gkrania-Klotsas Effrossyni
- Godden Jo
- Goldsmith Arthur
- Graham Clive
- Green Christopher A.
- Greenhalf William
- Greenhalf William
- Greenwood Edward J. D.
- Griffin Julian L.
- Griffiths Fiona
- Grimes Graeme
- Gu Quan
- Gunning Philip
- Gupta Rishi K.
- Halpin Sophie
- Hardwick Hayley
- Hardy Elaine
- Harrison Ewen M.
- Harrison Janet
- Hartley Catherine
- Hartshorn Stuart
- Harvey Daniel
- Havalda Peter
- Hawcutt Daniel B.
- Hendry Ross
- Herder Vanessa
- Ho Antonia
- Ho Antonia Ying Wai
- Hobrok Maria
- Hodgson Luke
- Holmes Anthony
- Horby Peter W.
- Hormis Anil
- Hughes Joseph
- Ijaz Samreen
- Iselin Louisa
- Jackson Clare
- Jacobs Michael
- Jain Susan
- Jarmson Innes
- Jarrett Ruth F.
- Jennings Paul
- Jensen Rebecca L.
- Jones Christopher B.
- Jones Trevor R.
- Kaliappan Agilan
- Kasipandian Vidya
- Keating Seán
- Kegg Stephen
- Kelsey Michael
- Kendall Jason
- Kerrison Caroline
- Kerslake Ian
- Khandaker Shadia
- Khoo Saye
- King Katharine
- Kiy Robyn T.
- Klenerman Paul
- Knight Stephen R.
- Koch Oliver
- Koduri Gouri
- Koshy George
- Koukorava Chrysa
- Kuchi Srikeerthana
- Laha Shondipon
- Laird Steven
- Lake Annette
- Lant Suzannah
- Larkin Susan
- Latawiec Diane
- Lavelle-Langham Lara
- Law Andrew
- Law Andrew
- Lee James
- Lee Jeffrey Y.
- Leeming Gary
- Lefteri Daniella
- Lehner Paul J.
- Leiner Tamas
- Lett Lauren
- Lewis Matthew R.
- Liggi Sonia
- Lillie Patrick
- Lim Wei Shen
- Limb James
- Linnett Vanessa
- Little Jeff
- Livoti Lucia A.
- Loney Colin
- Lytras Spyros
- Lyttle Mark
- MacLean Alan
- MacMahon Michael
- MacNaughton Emily
- Mancini Maria
- Mankregod Ravish
- Marsh Laura
- Marti Matthias
- Maslen Lynn
- Massey Hannah
- Masson Huw
- Matovu Elijah
- Maziere Nicole
- McCafferty Sarah
- McCullough Katherine
- McDonald Sarah
- McDonald Sarah E.
- McEvoy Laurence
- McEwen Ruth
- McLauchlan John
- Mclean Kenneth A.
- Meda Manjula
- Mentzer Alexander J.
- Merson Laura
- Metelmann Soeren
- Meynert Alison
- Meynert Alison M.
- Miah Nahida S.
- Middleton Joanna
- Mills Gary
- Minton Jane
- Mirfenderesky Mariyam
- Mitchell Joyce
- Mohandas Kavya
- Mok Quen
- Moon James
- Moore Elinoor
- Moore Shona C.
- Moore Shona C.
- Morgan Patrick
- Morrice Kirstie
- Morris Craig
- Mortimore Katherine
- Moses Samuel
- Mpenge Mbiye
- Mulla Rohinton
- Murphy Derek
- Murphy Ellen G.
- Murphy Lee
- Murphy Lee
- Murphy Michael
- Nagarajan Thapas
- Nagel Megan
- Nelson Mark
- Noerenberg Marko
- Norman Lisa
- Norris Lillian
- Noursadeghi Mahdad
- O?Shea Matthew K.
- Olanipekun Michael
- Oosthuyzen Wilna
- Openshaw Peter J. M.
- Openshaw Peter J. M.
- Osagie Anthonia
- Ostermann Marlies
- Otahal Igor
- Pais Mark
- Palmalux Natasha
- Palmarini Massimo
- Palmarini Massimo
- Palmieri Carlo
- Palmieri Carlo
- Panchatsharam Selva
- Papakonstantinou Danai
- Papineni Padmasayee
- Paraiso Hassan
- Patel Brij
- Pattison Natalie
- Paxton William A.
- Penrice-Randal Rebekah
- Pepperell Justin
- Peters Mark
- Phull Mandeep
- Pilgrim Jack
- Pinto Rute M.
- Pintus Stefania
- Pius Riinu
- Planche Tim
- Plotkin Daniel
- Pollakis Georgios
- Post Frank
- Price David
- Price Nicholas
- Prince Tessa
- Prout Rachel
- Rae Nikolas
- Rambaut Andrew
- Reschreiter Henrik
- Reynolds Tim
- Reynolds Will
- Richardson Neil
- Ridley P. Matthew
- Rihn Suzannah J.
- Roberts Devender
- Roberts Mark
- Roberts Stephanie
- Robertson David L.
- Robertson David L.
- Rose Alistair
- Rousseau Guy
- Ruge Bobby
- Russell Clark D.
- Ryan Brendan
- Sales Debby
- Saluja Taranprit
- Sancho-Shimizu Vanessa
- Sands Caroline J.
- Saviciute Egle
- Schmid Matthias L.
- Scott Janet T.
- Scott-Brown James
- Semple Malcolm G.
- Semple Malcolm G.
- Shah Aarti
- Shankar-Hari Manu
- Shanmuga Prad
- Sharma Anil
- Shaw Catherine A.
- Shaw Victoria
- Shaw Victoria E.
- Shawcross Anna
- Shears Rebecca K.
- Sigfrid Louise
- Singh Pooni Jagtur
- Sizer Jeremy
- Small Benjamin
- Smith Richard
- Snelson Catherine
- Solomon Tom
- Spencer Rebecca G.
- Spittle Nick
- Sriskandan Shiranee
- Staines Nikki
- Stambach Tom
- Stanton Richard J.
- Stewart Douglas G.
- Stewart Richard
- Stuart David
- Subramaniam Krishanthi S.
- Subudhi Pradeep
- Sugrue Elena
- Summers Charlotte
- Swann Olivia V.
- Swingler Simon
- Szakmany Tamas
- Szemiel Agnieska
- Taggart Aislynn
- Takats Zoltan
- Takis Panteleimon
- Tanianis-Hughes Jolanta
- Tatham Kate
- Tedder Richard S.
- Thomas Jo
- Thomas Jordan
- Thompson A. A. Roger
- Thompson Chris
- Thompson Robert
- Thomson Emma C.
- Thwaites Ryan S.
- Tridente Ascanio
- Trindade Maranhão Costa Fabio
- Trochu Erwan
- Tupper-Carey Darell
- Turnbull Matthew L.
- Turtle Lance C. W.
- Twagira Mary
- Vallotton Nick
- van Tonder Libby
- Vancheeswaran Rama
- Varjak Margus
- Vincent-Smith Lisa
- Visuvanathan Shico
- Vuylsteke Alan
- Waddy Sam
- Wake Rachel
- Walden Andrew
- Wang Bo
- Wang Eddie C. Y.
- Welters Ingeborg
- Wham Murray
- Whitehouse Tony
- Whittaker Paul
- Whittington Ashley
- Wickenhagen Arthur
- Wijesinghe Meme
- Wilcock Eve
- Williams Martin
- Wilson Lawrence
- Wilson Sam J.
- Winchester Stephen
- Wiselka Martin
- Wolverson Adam
- Wootton Daniel G.
- Workman Andrew
- Wrobel Nicola
- Yates Bryan
- Young Peter
- Zambon Maria
- Zhang J. Eunice
- Publication venue
- 'American Association for the Advancement of Science (AAAS)'
- Publication date
- 29/10/2021
- Field of study
Inherited genetic factors can influence the severity of COVID-19, but the molecular explanation underpinning a genetic association is often unclear. Intracellular antiviral defenses can inhibit the replication of viruses and reduce disease severity. To better understand the antiviral defenses relevant to COVID-19, we used interferon-stimulated gene (ISG) expression screening to reveal that OAS1, through RNase L, potently inhibits SARS-CoV-2. We show that a common splice-acceptor SNP (Rs10774671) governs whether people express prenylated OAS1 isoforms that are membrane-associated and sense specific regions of SARS-CoV-2 RNAs, or only express cytosolic, nonprenylated OAS1 that does not efficiently detect SARS-CoV-2. Importantly, in hospitalized patients, expression of prenylated OAS1 was associated with protection from severe COVID-19, suggesting this antiviral defense is a major component of a protective antiviral response
Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses
- Author
- Adeniji Kayode
- Aggleton John P.
- Agranoff Daniel
- Agwuh Ken
- Ahmed Katie A.
- Ail Dhiraj
- Al-Chalabi Ammar
- Aldera Erin L.
- Alegria Ana
- Alex Beatrice
- Allen Christopher M.
- Allen Sam
- Amin Jay
- Andrikopoulos Petros
- Angus Brian
- Armour Cherie
- Armstrong Jane A.
- Ashish Abdul
- Ashworth Milton
- Asiimwe Innocent G.
- Atkinson Dougal
- Bach Benjamin
- Baillie J. Kenneth
- Baillie J. Kenneth
- Baker Mark R.
- Bakshi Siddharth
- Barclay Wendy S.
- Bari Shahedal
- Barlow Gavin
- Barlow Samantha L.
- Barnass Stella
- Barrett Nicholas
- Barrett Suzanne
- Bassford Christopher
- Basu Neil
- Basude Sneha
- Batra Rahul
- Baxter David
- Beadsworth Michael
- Benjamin Laura
- Bernatoniene Jolanta
- Berridge John
- Berry Colin
- Best Nicola
- Bethlehem Richard
- Blackledge Bethan
- Boardman Sarah A.
- Bogaert Debby
- Booth Laura
- Bothma Pieter
- Bradley John R.
- Bradley John R.
- Breen David P.
- Breen Gerome
- Breen Gerome
- Brennan Benjamin
- Breuer Judith
- Brittain-Long Robin
- Broome Matthew R.
- Bullmore Edward
- Bullock Katie
- Bulteel Naomi
- Burden Tom
- Burtenshaw Andrew
- Butler Matthew
- Carlucci Nicola
- Carracedo Alejandra D.
- Carson Alan
- Carson Gail
- Caruth Vikki
- Cass Emily
- Catterall Benjamin W.
- Cavanagh Jonathan
- Cavanagh Jonathan
- Chadwick David
- Chambler Duncan
- Chand Meera
- Chechi Kanta
- Chee Nigel
- Child Jenny
- Chinnery Patrick F.
- Chiollaz Anne-Cecile
- Christmas David
- Christmas David M.
- Chukkambotla Srikanth
- Clark Jordan J.
- Clark Jordan J.
- Clark Richard
- Clark Tom
- Clarke Emily A.
- Clohisey Sara
- Cole Sarah
- Coleman Jonathan R.
- Coles Alaisdair
- Coles Alasdair J.
- Collie Ceryce
- Collie Ceryce
- Collini Paul
- Connor Marie
- Cooke Graham S.
- Cooper Louise
- Cosgrove Catherine
- Cossette Nadine
- Cousins David
- Coutts Audrey
- Cox Helen
- Cupitt Jason
- Cutino-Moguel Maria-Teresa
- da Silva Ana
- Dalton Jo
- Darby Alastair
- Dark Paul
- David Anthony S.
- Davies Nicholas
- Davis Christopher
- Dawson Chris
- de Silva Thushan
- Defres Sylviane
- Dervisevic Samir
- Digby Richard
- Dincarslan Oslem
- Docherty Annemarie B.
- Dodd Katherine C.
- Donegan Cara
- Donnelly Lorna
- Donnison Phil
- Donohue Chloe
- dos Santos Gonçalo
- Douthwaite Sam
- Drake Thomas M.
- Dregan Alex
- Drummond Andrew
- Duff Eugene
- Dumas Marc-Emmanuel
- Dunai Cordelia
- Dunai Cordelia
- Dunn Chris
- Dunning Jake
- DuRand Ingrid
- Dushianthan Ahilanadan
- Dyer Philip
- Dyer Tristan
- Easton Ava
- Ebrahimi Soraya
- Egbe Franklyn N.
- Elliott Angela
- Ellul Mark A.
- Evangelou Nikos
- Evans Anthony
- Evans Cariad
- Eziefula Chi
- Facer Bethany
- Fairfield Cameron J.
- Fawkes Angie
- Fegan Chrisopher
- Fernandes Peter M.
- Finch Lorna
- Finn Adam
- Fisher Lewis W.
- Flaherty Lisa
- Fletcher Tom
- Foster Terry
- Fower Andrew
- Fox Hannah
- Francis Richard
- Fullerton Duncan
- Gamble Carrol
- Garcia-Dorival Isabel
- Garg Atul
- Garg Sanjeev
- Garjani Afagh
- George Lily
- Gilchrist Tammy
- Girvan Michelle
- Gkrania-Klotsas Effrossyni
- Glen Kiran
- Godden Jo
- Goldsmith Arthur
- Graham Clive
- Grammatikopoulos Tassos
- Green Christoper A.
- Greenhalf William
- Gregory Rebecca
- Griffin Julian L.
- Griffiths Fiona
- Griffiths Michael
- Griffiths Michael
- Grimbly Victoria
- Grundmann Alexander
- Grundmann Alexander
- Gunatilake Savini
- Gunning Philip
- Gupta Rishi K.
- Hafezi Katarzyna
- Halpin Sophie
- Hamid Shahd H.
- Hampshire Adam
- Hannah C.
- Hardwick Hayley
- Hardwick Marc
- Hardy Elaine
- Harris Jade D.
- Harrison Ewan
- Harrison Ewen M.
- Harrison Janet
- Harrison Neil
- Harrison Neil A.
- Harrison Paul J.
- Hartley Catherine
- Hartmann Monika
- Hartshorn Stuart
- Harvey Daniel
- Havalda Peter
- Hawcutt Daniel B.
- Held Marie
- Hendry Ross
- Hetherington Claire
- Hiscox Julian
- Hobrok Maria
- Hodel Eva M.
- Hodgson Luke
- Holden Karl
- Holland Angela E.
- Holmes Anthony
- Horby Peter W.
- Hormis Anil
- Hotopf Matthew
- Howard Joanne
- Huang Yun
- Hughes Stella
- Husain Masud
- Ijaz Samreen
- Irani Sarosh
- Irani Sarosh R.
- Jackson Clare
- Jackson Thomas
- Jacobs Michael
- Jain Susan
- Jenkins Thomas M.
- Jennings Paul
- Jensen Rebecca L.
- Jezzard Peter
- Jones Christopher B.
- Jones Trevor R.
- Kaliappan Agilan
- Kasipandian Vidya
- Keating Seán
- Kegg Stephen
- Keller Simon
- Kelsey Michael
- Kendall Jason
- Kerrison Caroline
- Kerslake Ian
- Khandaker Shadia
- Khoo Saye
- King Katharine
- Kingston Nathalie
- Kiy Robyn T.
- Klenerman Paul
- Knight Stephen R.
- Knight Susan
- Koch Oliver
- Koduri Gouri
- Koshy George
- Koukorava Chrysa
- Kyaw Sandar
- Laha Shondipon
- Lahnsteiner Eva
- Laird Steven
- Lake Annette
- Lant Suzannah
- Larkin Susan
- Latawiec Diane
- Lavelle-Langham Lara
- Law Andrew
- Lee James
- Leek Charles
- Leeming Gary
- Lefteri Daniella
- Leibowitz Maya
- Leiner Tamas
- Lett Lauren
- Lewis Gabriella
- Lewis Matthew R.
- Liggi Sonia
- Lilleker James B.
- Lillie Patrick
- Lim Wei S.
- Limb James
- Linnett Vanessa
- Little Jeff
- Livoti Lucia A.
- Lunn Michael P.
- Lyttle Mark
- MacGillivray Louise
- MacIver Claire L.
- Maclean Alan
- MacMahon Michael
- MacNaughton Emily
- Madarshahian Daniel
- Mancini Maria
- Mankregod Ravish
- Mansoori Parisa
- Marsh Laura
- Martin Naomi
- Maslen Lynn
- Massey Hannah
- Masson Huw
- Matovu Elijah
- Maziere Nicole
- McCafferty Sarah
- McCullough Katherine
- McDonald Sarah
- McDonald Sarah E.
- McDonnell Gavin
- McEvoy Laurence
- McEwen Ruth
- McGlinchey Emily
- McIlwaine Ryan
- McIntosh Andrew M.
- McLauchlan John
- Mclean Kenneth A.
- Meda Manjula
- Menon David K.
- Menon David K.
- Mentzer Alexander J.
- Merson Laura
- Metelmann Soeren
- Meynert Alison M.
- Miah Nahida S.
- Michael Benedict D.
- Michael Benedict D.
- Middleton Joanna
- Miller Karla
- Mills Gary
- Minton Jane
- Mitchell Joyce
- Mohandas Kavya
- Mok Quen
- Monssen Dina
- Moon James
- Moore Elinoor
- Moore Shona C.
- Morgan Patrick
- Morrice Kirstie
- Morris Christopher M.
- Morris Craig
- Mortimore Katherine
- Moses Samuel
- Mpenge Mbiye
- Mulholland Ciaran
- Mulla Rohinton
- Murphy Derek
- Murphy Ellen G.
- Murphy Lee
- Murphy Michael
- Nagarajan Thapas
- Nagel Megan
- Nair Akshay
- Needham Edward
- Needham Edward J.
- Nelson Mark
- Newcombe Virginia
- Nicholas Nathalie
- Nicholson Timothy
- Norman Lisa
- Norris Lillian
- Norris Lucy
- Norton Emma
- Noursadeghi Mahdad
- O'Malley Ronan
- O'Shea Matthew K.
- Olanipekun Michael
- Oosthuyzen Wilna
- Openshaw Peter J.
- Openshaw Peter J.
- Osagie Anthonia
- Ostermann Marlies
- Otahal Igor
- Paddick Stella-Maria
- Pais Mark
- Palmarini Massimo
- Palmieri Carlo
- Palmos Alish
- Palmos Alish
- Panchatsharam Selva
- Papakonstantinou Danai
- Papineni Padmasayee
- Paraiso Hassan
- Patel Arvind
- Patel Brij
- Pattison Natalie
- Paxton William A.
- Peacock Sharon
- Pendered Sophie
- Penrice-Randal Rebekah
- Pepperell Justin
- Peters Mark
- Phull Mandeep
- Pilgrim Jack
- Pintus Stefania
- Pius Riinu
- Planche Tim
- Plotkin Daniel
- Pollak Thomas
- Pollakis Georgios
- Pooni Jagtur S.
- Post Frank
- Price David
- Price Nicholas
- Prince Tessa
- Prout Rachel
- Rae Nikolas
- Rambaut Andrew
- Ren Alexander
- Reschreiter Henrik
- Reynolds Tim
- Reynolds Will
- Richardson Neil
- Ridley P. M.
- Roberts Angela
- Roberts Devender
- Roberts Mark
- Roberts Stephanie
- Robertson David L.
- Rogers Henry C.
- Rose Alistair
- Rota Silvia
- Rousseau Guy
- Ruge Bobby
- Russell Clark D.
- Ryan Brendan
- Sales Debby
- Salman Rustam A.
- Saluja Taranprit
- Samuel Merna
- Sanchez Jean-Charles
- Sancho-Shimizu Vanessa
- Sands Caroline J.
- Sargent Brendan
- Saviciute Egle
- Sawcer Stephen J.
- Schmid Matthias L.
- Scott Janet T.
- Scott-Brown James
- Seed Adam W.
- Semple Malcolm G.
- Semple Malcolm G.
- Semple Scott
- Shah Aarti
- Shankar-Hari Manu
- Shanmuga Prad
- Sharma Anil
- Sharma Parul
- Shaw Catherine A.
- Shaw Pamela J.
- Shaw Victoria
- Shaw Victoria E.
- Shawcross Anna
- Shears Rebecca K.
- Sieradzki Adam
- Sigfrid Louise
- Singh Bhagteshwar
- Sizer Jeremy
- Small Benjamin
- Smith Craig J.
- Smith Jacqueline
- Smith Richard
- Smith Stephen
- Snelson Catherine
- Solomon Tom
- Solomon Tom
- Spencer Rebecca G.
- Spittle Nick
- Sriskandan Shiranee
- Staines Nikki
- Stambach Tom
- Stewart James P.
- Stewart Richard
- Stirrups Kathy
- Stuart David
- Subramaniam Krishanthi
- Subramaniam Krishanthi S.
- Subudhi Pradeep
- Summers Charlotte
- Sunderland Geraint
- Swann Olivia V.
- Szakmany Tamas
- Szemiel Agnieska
- Taams Leonie
- Taams Leonie S.
- Taggart Aislynn
- Tait Sarah
- Takats Zoltan
- Takis Panteleimon
- Tamborska Arina
- Tanianis-Hughes Jolanta
- Tatham Kate
- Tato Esteban
- Taylor John-Paul
- Tedder Richard S.
- Tharmaratnam Kukatharmini
- Thomas Jo
- Thomas Jordan
- Thomas Rhys H.
- Thompson A. A. R.
- Thompson Chris
- Thompson Robert
- Thomson Emma
- Thomson Emma C.
- Thwaites Ryan S.
- Tonder Libby v.
- Tridente Ascanio
- Trochu Erwan
- Tupper-Carey Darell
- Turtle Lance C.
- Twagira Mary
- Underwood Jonathan
- Upthegrove Rachel
- Vallotton Nick
- van Daniel J.
- Vancheeswaran Rama
- Veenith Tonny
- Venneri Annalena
- Vincent Angela
- Vincent Angela
- Vincent Rachel
- Vincent-Smith Lisa
- Visuvanathan Shico
- Vuylsteke Alan
- Waddy Sam
- Wai Antonia Y.
- Wake Rachel
- Walden Andrew
- Welters Ingeborg
- Wham Murray
- Whitehouse Tony
- Whittaker Paul
- Whittington Ashley
- Wijesinghe Meme
- Wilcock Eve
- Williams Guy B.
- Williams Martin
- Williams Robyn
- Williams Steven
- Wilson Lawrence
- Winchester Stephen
- Wiselka Martin
- Wolverson Adam
- Wong Sui H.
- Wood Greta K.
- Wood Greta K.
- Wood Nicholas
- Wootton Daniel G.
- Workman Andrew
- Wrobel Nicola
- Yates Bryan
- Young Peter
- Zambon Maria
- Zandi Michael S.
- Zelaya Fernando
- Zhang J. E.
- Publication venue
- Nature Research
- Publication date
- 22/12/2023
- Field of study
To understand neurological complications of COVID-19 better both acutely and for recovery, we measured markers of brain injury, inflammatory mediators, and autoantibodies in 203 hospitalised participants; 111 with acute sera (1–11 days post-admission) and 92 convalescent sera (56 with COVID-19-associated neurological diagnoses). Here we show that compared to 60 uninfected controls, tTau, GFAP, NfL, and UCH-L1 are increased with COVID-19 infection at acute timepoints and NfL and GFAP are significantly higher in participants with neurological complications. Inflammatory mediators (IL-6, IL-12p40, HGF, M-CSF, CCL2, and IL-1RA) are associated with both altered consciousness and markers of brain injury. Autoantibodies are more common in COVID-19 than controls and some (including against MYL7, UCH-L1, and GRIN3B) are more frequent with altered consciousness. Additionally, convalescent participants with neurological complications show elevated GFAP and NfL, unrelated to attenuated systemic inflammatory mediators and to autoantibody responses. Overall, neurological complications of COVID-19 are associated with evidence of neuroglial injury in both acute and late disease and these correlate with dysregulated innate and adaptive immune responses acutely
John Plaifere (d.1632) on conditional predestination: a well-mixed version of scientia media
- Author
- Arminius Jacobus
- Baro Peter
- Baxter Richard
- Bryant Barry E.
- Cattermole Richard
- Coffey John
- Cust Richard
- Dekker Eef
- Dodds Gregory D.
- Fielding John
- Fincham Kenneth
- Goad Thomas
- Hoenderdaal G. J.
- Hughes Seán F.
- Jae-Eun Park
- Milton Anthony
- Molina Luis de
- Montagu Richard
- Muller Richard A.
- Muller Richard A.
- Muller Richard A.
- Muller Richard A.
- Plaifere John
- Plaifere John
- Porter H. C.
- Quantin Jean-Louis
- Schaff Philip
- Stanglin Keith D.
- Stanglin Keith D.
- Todd Margo
- Turretin Francis
- Twisse William
- Tyacke N.R.N.
- Tyacke N.R.N.
- Tyacke N.R.N.
- Van Asselt W. J.
- Venn John
- White Peter
- Publication venue
- 'Informa UK Limited'
- Publication date
- Field of study
Beneath the organ trade: a critical analysis of the organ trafficking discourse
- Author
- A Dundes
- A Mills
- AE Clarke
- AF Vecchi De
- AL Caplan
- AM Nahas El
- B Donovan
- C Douzinas
- CA Erin
- D Brennan
- D Budiani‐Saberi
- D Castro
- D Joralemon
- D Martin
- D Rothman
- DA Budiani
- DA Budiani-Saberi
- DA Budiani‐Saberi
- F Ambagtsheer
- F Delmonico
- FL Delmonico
- G Cohen
- G Ellison
- GM Danovitch
- H King
- IG Cohen
- J Berman
- J Zargooshi
- JM Appel
- JM Chacón
- JO Davidson
- JV Mchale
- L Cohen
- LM Agustin
- M Goyal
- M Makinen
- M Moniruzzaman
- MA Peters
- MJ Alsharif
- MW Mutua
- N Rose
- N Rose
- N Scheper‐Hughes
- P Andreas
- R Kishore
- R Weitzer
- R Weitzer
- RK Panjabi
- RL Mendoza
- RL Mendoza
- S Cohen
- S Hamdy
- S Lundin
- S Meyer
- S Naqvi
- S Yea
- Seán Columb
- SL White
- SP Calandrillo
- T Lemke
- TG Blanchette
- TH Jafar
- TM Steinfatt
- V Campion-Vincent
- Y Shimazono
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
The “Dark Welsh” as Slaves and Slave Traders in Exeter Book Riddles 52 and 72
- Author
- Bassett Steven
- Bately Janet M.
- Bitterli Dieter
- Bosanquet Geoffrey
- Bosworth Joseph
- Brooke Stopford A
- Cameron A.
- Charles B. G.
- Charles-Edwards T. M
- Charles-Edwards T. M
- Charles-Edwards T. M
- Cockayne T. O.
- Crossley-Holland Kevin
- Dafydd Jenkins
- Darlington R. R.
- Davies R. R
- Davies Wendy
- Dietrich F.
- Dobbie Elliot Van Kirk
- Duffy Seán
- Dyer Christopher
- Etchingham Colman
- Faull Margaret Lindsay
- Ford W. J
- Garmonsway G. N.
- Gelling Margaret
- Gneuss Helmut
- Goodall I. H
- Grein C. W. M.
- Grein C. W. M.
- Healey Antonette diPaolo
- Henning J.
- Herschend Frands
- Hessels J. H.
- Holm Poul
- Holthausen Ferdinand
- Holthausen Ferdinand
- Hooke Della
- Hooke Della
- Howe Nicholas
- Hughes P
- Irvine Susan
- Krapp George Phillip
- Lapidge Michael
- Lapidge Michael
- Lerer Seth
- Liebermann Felix
- Lindy Brady
- Maund K
- McAll Christopher
- Meritt H. D.
- Mitchell Bruce
- Moore-Colyer Richard J
- Muir Bernard J.
- Mytum Harold
- Niles John D
- Niles John D
- Noble Frank
- Page Raymond Ian
- Patterson Nerys
- Peile J. H. F.
- Pelteret David A. E.
- Pelteret David A. E.
- Pelteret David A. E.
- Pheifer J. D.
- Pollington Stephen
- Powell F
- Rule Martin
- Rulon-Miller Nina
- Russell Paul
- Scott B. G.
- Smith D. K
- Stryker W. G.
- Swartz Dorothy Dilts
- Szarmach Paul E
- Tanke John W.
- Thorpe Benjamin
- Toller T. Northcote
- Trautmann Moritz
- Trautmann Moritz
- Tupper Frederick Jr.
- Voss Manfred
- Walker David
- Walters D. B
- Walz John A
- Welch Martin
- Wilcox Jonathan
- Williamson Craig
- Winterbottom Michael
- Wormald Patrick
- Publication venue
- 'Informa UK Limited'
- Publication date
- 26/02/2014
- Field of study
The imagery of captivity found within Exeter Book Riddles 52 and 72 has been understood to link Welsh slaves with the cattle they herd, for each riddle features an ethnically distinct “dark Welsh” figure performing agricultural work. This article argues that key details suggest that these captives can also be read as humans, alluding to the historical roles of the Welsh as both slaves and slave traders in Anglo-Saxon England. While scholars have long realised that these riddles call attention to ethnic and class difference by linking racially distinct Welsh servitude to hard manual labour, particularly to oxen, the Welsh were also active slave raiders of their own people. In their portrayals of ethnically distinct Welsh who control bound captives, this article argues that these riddles also allude to the role of the Welsh in the slave trade as brokers of human merchandise. These riddles, then, reveal the complexities of the period by illuminating the contradictory identity of the Welsh as both victims and perpetrators of the slave trade in Anglo-Saxon England
Canada
- Author
- A. Amprimoz
- A. Amprimoz
- A. Blott
- A. Boutelle
- A. Brodie
- A. Feder
- A. Gandolfo
- A. Purdy
- A. Roche
- A.C. Stewart
- A.D. Armitage
- A.E. Davidson
- A.W. Riley
- Acland Lois
- Alianak Hrant
- Allen Robert
- Amprimoz Alexandre
- Andrus David
- Annand Alan Mark
- Aquin Hubert
- Ardies Tom
- Atwood Margaret
- Atwood Margaret
- Aubert Rosemary
- Austin Don
- Avery Martin
- Avison Margaret
- Avison Margaret
- B. Cameron
- B. Daurio
- B. Davies
- B. Fawcett
- B. Godard
- B. Hehner
- B. Kingstone with
- B. Rasporich
- B. Wood
- B. Wood
- B.M. Ewing
- Bailey Alfred G.
- Bailey Bill
- Barbour Douglas
- Bartlett Brian
- Bartlette Sandra
- Bauer William
- Beissel Henry
- Beresford-Howe Constance
- Berton Pierre
- Biderman Ruth
- Bonnie Fred
- Bowering George
- Bowie Douglas
- Boyarsky Abraham
- Brownlow Edward William
- Bullock Michael
- Burns Mary
- Buyukmihci H.S.
- C. Belkin
- C. Hosek
- C. Pagnoulle
- C. Pollack
- C. Rosen
- C. Thomas
- C.H. Gervais
- C.L. Smiley
- C.T. Bissell
- Calder Ruth
- Callaghan Morley
- Canadian
- Carman Bliss
- Carr Emily
- Castillo Charles
- Clark Joan
- Clute John
- Cohen Leonard
- Cohen Matt
- Collier Diana G.
- Colson Theodore
- Corning Emilia
- Crowe Eleanor
- Crowell Peter
- Cuevas Ernesto
- Cull David
- D. Arnason
- D. Barbour
- D. Barbour
- D. Barbour
- D. Bessai
- D. Bessai
- D. Day
- D. Edmonds
- D. Godfrey
- D. Kent
- D. Ketterer
- D. Latham
- D. Livesay
- D. Livesay
- D. Mantz
- D. Mantz
- D. Rubin.
- D.E.D. Downey
- D.J. Dooley
- D.W. Russell
- D.W. Russell
- Dabydeen Cyril
- Dagg Mel
- Davies Ken
- Davies Robertson
- Davies Robertson
- Dawson Fielding
- Denison Merrill
- Deverell Rex
- Dewdney Chris
- Dickinson Don
- Dickinson Mary Lou
- Doran Jane
- Doubt Bryan
- Drabek Jan
- Dudek Louis
- Duncan Sara Jeannette
- Dunmore Spencer
- E. Cameron
- E. Jewinski
- E. Mandel
- E. Mandel
- E. Seidner
- E. Wachtel
- Eggleston Wilfrid
- Egyedi Bela
- Eirikson Irene
- Elves Hazel
- Engel Howard
- Engel Marian
- Enright William
- Evans Cicely Louise
- Everson R.G.
- F. Birbalsingh
- F. Cogswell
- F. Davey
- F. Spitzer
- F. Spoerly
- F. Teague
- Fagan Cary
- Fawcett Brian
- Fawcett Brian
- Fawcett Brian
- Ferguson Trevor
- Ferron Jacques
- Finkenbine Mark
- Fischman Sheila
- Fletcher Peggy
- Fobes Greg
- Ford Cathy
- Frye Northrop
- Frye Northrop
- Fuchs Terry
- G. Geddes
- G. Geddes
- G. Hancock
- G. Hancock
- G. Hancock
- G. Marcotte
- G. McWhirter
- G. Melnyk
- G. Murray
- G. Ryga
- G. Ryga
- G. Woodcock
- G. Woodcock
- G. Woodcock
- Gallant Mavis
- Galt John
- Garsonnin Eric
- Garwood Lana
- Gatenby Greg
- Gauvreau Claude
- Gibbs Robert
- Gilbert Gerry
- Gillis Susan
- Godfrey Dave
- Goldsmith Oliver
- Gorman LeRoy
- Gould Terry
- Govier Katherine
- Gregg John
- Greig Hugh
- Grove Frederick Philip
- Gutteridge Don
- Gérin-Lajoie Antoine
- H. de Santana
- H. Porter
- H.G. Edinger
- Haggerty Joan
- Haig-Brown Roderick
- Haliburton Thomas Chandler
- Haliburton Thomas Chandler
- Halko Irene
- Hall Chipman
- Halperin Irving
- Hamilton Pierce Stevens
- Hamilton Susan L.
- Hardy Isabeth
- Harlow Robert
- Harris John
- Harris Paula
- Harrison Devin
- Hayman Robert
- Heide Christopher
- Heide Christopher
- Hekkanen Ernest
- Hendry Tom
- Hendry Tom
- Hendry Tom
- Hiebert Paul
- Hill Kathy
- Hine Daryl
- Hodgins Jack
- Hollingshead Greg
- Hollingsworth Margaret
- Hood Hugh
- Hooper Mollie
- Horst Roger
- Hosein Jennifer
- Howe Joseph
- Howells Annie
- Hubert Cam
- Hubert Cam
- Huggan Isabel
- Huser Glen
- Hutchison Joe
- Hébert Anne
- I. Balfour
- I. Carrington
- I. Young
- Ingram Alyce
- Ireland Ann
- J. Ball
- J. Baxter
- J. David
- J. Hofsess
- J. Hofsess
- J. Lye
- J. Mallinson
- J. Neufeld
- J. Pivato
- J. Reaney
- J. Sowby
- J.C. Green
- J.H. Rosenburg
- J.M. Kertzer
- J.M. Yates
- J.M. Zezulka
- J.R. Struthers
- J.W. Foster
- J.W. Watson
- Jarvis Thomas Stinson
- Jewinski Hans
- Jiles Paulette
- Johnson G. Bertha
- Jonas George
- Jonas George
- Julian Marilyn
- K. Echlin
- K. Norris
- K. Norris
- K. Radu
- K. Russell
- K. Thompson
- K.J. Hughes
- K.P. Stich
- Keenleyside T.A.
- Kemp Penny
- Kemp Penny
- Kertes Joseph
- Kidd Flora
- Kirby William
- Kleiman Ed'
- Klein A.M.
- Knox Alexander
- Konyves Tom
- Konyves Tom
- Kreisel Henry
- Kreisel Henry
- Kroetsch Robert
- Kumin Maxine
- L. McMullen
- L. Sandler
- L.B. Meckler
- L.C. Gottlieb
- L.M. Shirinian
- Lamb Murray
- Landy Francis
- Lane John
- Lauder Scott
- Laurence Margaret
- Lavoie Stephanie
- Layton Aviva
- Layton Irving
- Layton Irving
- Leacock Stephen
- Leckie Keith
- Lee Dennis
- Lemm Richard
- Leprohon Rosanna
- LeSueur William
- Levis Deanna
- Lewis Ruth C.
- Lipkis Jeff
- Livesay Dorothy
- Longmore George
- Loomer L.S.
- Lowry Margerie Bonner
- Lowther Pat
- M. Acorn
- M. Acorn
- M. Anderson
- M. Atwood
- M. Atwood
- M. Bowering
- M. Boweririg
- M. Dorsinville
- M. Ford
- M. Kennedy
- M. Macina
- M. McLuhan
- M. Micros
- M. Page
- M. Page
- M. Ross
- M. Vipond
- M. Zola
- M.B. Oliver
- M.C. Wilson
- M.G. Hesse
- MacCormack Terry
- Macphail Andrew
- Madott Darlene
- Mahood Maurice
- Mandel Eli
- Mandrake Jill
- Marcotte Gilles
- Margoshes Dave
- Marlatt Daphne
- Marlatt Daphne
- Marshall Joyce
- Marshall Tom
- Mason Mike
- Mathews Laurence
- Mayhew Vic
- McClellan Pat
- McClung Nellie
- McCurry Jim
- McFadden David
- McFadden David
- McKenzie Earl
- McKinnon Barry
- McLean Anne
- McLean James S.
- McLuhan Marshall
- Metcalf John
- Metcalf John
- Mills John
- Minions Stephen
- Mitchell Ken
- Mitchell W.O.
- Mombourquette Michael
- Moore Brian
- Moore Brian
- Moore Ken
- Morton Lionel
- Mowat Farley
- Mrkich Dan
- Munro Alice
- Munro Alice
- Murphy Jeremiah V.
- Musgrave Susan
- N. Carson
- N.W. Fraser
- Neil Al
- Newlove. John
- Nichol B.P.
- Nichol B.P.
- Nichol B.P.
- Nightingale Christine
- Nowlan Alden
- Nowlan Alden
- Nutting Leslie
- O'Flaherty Patrick
- Oates Joyce
- Oates Joyce Carol
- Okun Nicole
- Ondaatje Michael
- Ondaatje Michael
- Ord Douglas
- Orde Lewis
- P. Baltensperger
- P. Hay
- P. Hunt
- P. Monk
- P. Morley
- P. Morley
- P. Quartermain
- P. Stevens
- P. Stevens
- P. Thompson.
- P.F. McNally
- Palmer John
- Parsons Fay
- Petersen Olive MacKay
- Plantos Ted
- Powell Craig
- Pratt E.J.
- Purdy A.
- R. Cameron
- R. Cluett
- R. Fulford
- R. Huebert
- R. LaBonte
- R. Mathews
- R. Page
- R. Siemens
- R. Skelton
- R. Smith
- R. Stuart
- R. Sutherland
- R.A. Lecker
- R.A. Lecker
- R.D. MacDonald
- Raddall Thomas H.
- Radu Kenneth
- Reaney James
- Richards David
- Riches Brenda
- Richler Mordecai
- Riddell John
- Riis Sharon
- Ringwood Gwen Pharis
- Ritter Erika
- Roberts Charles G.D.
- Roberts Charles G.D.
- Roberts Kevin
- Robertson Don
- Robin Skelton
- Robin Donald M.
- Robinson Spider
- Rogers Linda
- Rohmer Richard
- Rooke Constance
- Rose Mildred A.
- Ross D.
- Ross James
- Ross Veronica
- Ross W.W.E.
- Rosta Helen
- Rowdon Larry
- S. Bonnycastle
- S. Clarkson
- S. Djwa
- S. Hatfield
- S. Martin
- S. Morrison
- S. Nagarajan
- S. Solecki
- S. Solecki
- S. Symons
- S.E. Grace
- S.J. Wilson
- Salmaniw Stephen
- Sandor Karl
- Sangster Charles
- Saul John
- Schoemperlen Diane
- Schroeder Andreas
- Schweers Gordon
- Scott Duncan Campbell
- Scott Duncan Campbell
- Scott F.R.
- Seal Graham
- Service Robert W.
- Seton Ernest Thompson
- Seán Virgo
- Sharpe. David
- Sherman K.J.
- Sherman Ken
- Sherrin Robert G.
- Shields Carol
- Shirinian Lorne M.
- Simmie Lois
- Simpson Gregg
- Simpson Leo
- Slater Ian
- Smith A.J.M.
- Smith D.C.
- Smith D.L.M.
- Souster Raymond
- Stange Kenneth
- Staniforth Richard
- Station F.
- Stead Robert
- Stein David
- Stein Louise
- Stenson Fred
- Stephen Sid
- Stevens Peter
- Stevenson Lionel
- Stewart A.C.
- Sturmanis Dona
- Such
- Suthren Victor
- Symons Scott
- Symons T.H.B.
- Szumigalski Anne
- T. Hendry
- T. Marshall
- T. Marshall
- T. Marshall
- T. Marshall
- T. Quigley
- T. Stephenson
- T. Wayman
- T.D. MacLulich
- T.D. MacLulich
- T.E. Tausky
- T.Q. Dombrowski
- Teed Roy
- Templeton Charles
- Thomas Audrey
- Thompson James
- Thompson John R.
- Thompson Kent
- Tippett Maria
- Tocque Philip
- Traill Catherine Parr
- Tupper Dorothy
- V. Boland
- Valgardson W.D.
- Valgardson W.D.
- Van der Schel Sjors
- Van Dyck Henry
- Van Rjndt Philippe
- Virgo Sean
- Vlahov Ed
- W. Cude
- W. Cude
- W. Kirkconnell
- W. Pache
- W.H. New
- W.H. New
- Wade John Stevens
- Walker Doris
- Walters Harold N.
- Waltner-Toews David
- Ward Frederick
- Watmough David
- Watt F.W.
- Weinzweig Helen
- Wheatley Patience
- White Marilyn
- Whyte Don
- Wiebe Armin
- Wiebe Rudy
- Wilford M.
- Wilson Ethel
- Windsor Robert
- Woodcock George
- Wreggitt Andrew
- Wright Doug
- Wright Richard B.
- Wynand Derk
- Young David
- Publication venue
- 'SAGE Publications'
- Publication date
- Field of study