The Equivalence Principle in the Non-baryonic Regime

We consider the empirical validity of the equivalence principle for non-baryonic matter. Working in the context of the TH\epsilon\mu formalism, we evaluate the constraints experiments place on parameters associated with violation of the equivalence principle (EVPs) over as wide a sector of the standard model as possible. Specific examples include new parameter constraints which arise from torsion balance experiments, gravitational red shift, variation of the fine structure constant, time-dilation measurements, and matter/antimatter experiments. We find several new bounds on EVPs in the leptonic and kaon sectors.Comment: 22 pages, late

Near-Infrared Molecular Hydrogen Emission from the Central Regions of Galaxies: Regulated Physical Conditions in the Interstellar Medium

The central regions of many interacting and early-type spiral galaxies are actively forming stars. This process affects the physical and chemical properties of the local interstellar medium as well as the evolution of the galaxies. We observed near-infrared H2 emission lines: v=1-0 S(1), 3-2 S(3), 1-0 S(0), and 2-1 S(1) from the central ~1 kpc regions of the archetypical starburst galaxies, M82 and NGC 253, and the less dramatic but still vigorously star-forming galaxies, NGC 6946 and IC 342. Like the far-infrared continuum luminosity, the near-infrared H2 emission luminosity can directly trace the amount of star formation activity because the H2 emission lines arise from the interaction between hot and young stars and nearby neutral clouds. The observed H2 line ratios show that both thermal and non-thermal excitation are responsible for the emission lines, but that the great majority of the near-infrared H2 line emission in these galaxies arises from energy states excited by ultraviolet fluorescence. The derived physical conditions, e.g., far-ultraviolet radiation field and gas density, from [C II] and [O I] lines and far-infrared continuum observations when used as inputs to photodissociation models, also explain the luminosity of the observed H2 v=1-0 S(1) line. The ratio of the H2 v=1-0 S(1) line to far-IR continuum luminosity is remarkably constant over a broad range of galaxy luminosities; L_H2/L_FIR = about 10^{-5}, in normal late-type galaxies (including the Galactic center), in nearby starburst galaxies, and in luminous IR galaxies (LIRGs: L_FIR > 10^{11} L_sun). Examining this constant ratio in the context of photodissociation region models, we conclude that it implies that the strength of the incident UV field on typical molecular clouds follows the gas density at the cloud surface.Comment: Accepted for ApJ, 24 pages, 17 figures, for complete PDF file, see http://kao.re.kr/~soojong/mypaper/2004_pak_egh2.pd

A role for human leucocyte antigens in the susceptibility to SARS‐Cov‐2 infection observed in transplant patients

We analysed data from 80 patients who tested positive for SARS‐CoV‐2 RNA who had previously been HLA typed to support transplantation. Data were combined from two adjacent centres in Manchester and Leeds to achieve a sufficient number for early analysis. HLA frequencies observed were compared against two control populations: first, against published frequencies in a UK deceased donor population (n = 10,000) representing the target population of the virus, and second, using a cohort of individuals from the combined transplant waiting lists of both centres (n = 308), representing a comparator group of unaffected individuals of the same demographic. We report a significant HLA association with HLA‐ DQB1*06 (53% vs. 36%; p < .012; OR 1.96; 95% CI 1.94–3.22) and infection. A bias towards an increased representation of HLA‐A*26, HLA‐DRB1*15, HLA‐DRB1*10 and DRB1*11 was also noted but these were either only significant using the UK donor controls, or did not remain significant after correction for multiple tests. Likewise, HLA‐A*02, HLA‐B*44 and HLA‐C*05 may exert a protective effect, but these associations did not remain significant after correction for multiple tests. This is relevant information for the clinical management of patients in the setting of the current SARS‐CoV‐2 pandemic and potentially in risk‐assessing staff interactions with infected patients

A review of recent perspectives on biomechanical risk factors associated with anterior cruciate ligament injury

There is considerable evidence to support a number of biomechanical risk factors associated with non-contact anterior cruciate ligament (ACL) injury. This paper aimed to review these biomechanical risk factors and highlight future directions relating to them. Current perspectives investigating trunk position and relationships between strength, muscle activity and biomechanics during landing/cutting highlight the importance of increasing hamstring muscle force during dynamic movements through altering strength, muscle activity, muscle length and contraction velocity. In particular, increased trunk flexion during landing/cutting and greater hamstring strength are likely to increase hamstring muscle force during landing and cutting which have been associated with reduced ACL injury risk. Decision making has also been shown to influence landing biomechanics and should be considered when designing tasks to assess landing/cutting biomechanics. Coaches should therefore promote hamstring strength training and active trunk flexion during landing and cutting in an attempt to reduce ACL injury risk.Peer reviewe

AKARI and BLAST Observations of the Cassiopeia A Supernova Remnant and Surrounding Interstellar Medium

We use new large area far infrared maps ranging from 65 - 500 microns obtained with the AKARI and the Balloon-borne Large Aperture Submillimeter Telescope (BLAST) missions to characterize the dust emission toward the Cassiopeia A supernova remnant (SNR). Using the AKARI high resolution data we find a new "tepid" dust grain population at a temperature of ~35K and with an estimated mass of 0.06 solar masses. This component is confined to the central area of the SNR and may represent newly-formed dust in the unshocked supernova ejecta. While the mass of tepid dust that we measure is insufficient by itself to account for the dust observed at high redshift, it does constitute an additional dust population to contribute to those previously reported. We fit our maps at 65, 90, 140, 250, 350, and 500 microns to obtain maps of the column density and temperature of "cold" dust (near 16 K) distributed throughout the region. The large column density of cold dust associated with clouds seen in molecular emission extends continuously from the surrounding interstellar medium to project on the SNR, where the foreground component of the clouds is also detectable through optical, X-ray, and molecular extinction. At the resolution available here, there is no morphological signature to isolate any cold dust associated only with the SNR from this confusing interstellar emission. Our fit also recovers the previously detected "hot" dust in the remnant, with characteristic temperature 100 K.Comment: Accepted for publication in the Astrophysical Journal. Maps and related data are available at http://blastexperiment.info

A comparative HST imaging study of the host galaxies of radio-quiet quasars, radio-loud quasars and radio galaxies: Paper I

We present the first results from a major HST WFPC2 imaging study aimed at providing the first statistically meaningful comparison of the morphologies, luminosities, scalelengths and colours of the host galaxies of radio-quiet quasars, radio-loud quasars, and radio galaxies. We describe the design of this study and present the images which have been obtained for the first half of our 33-source sample. We find that the hosts of all three classes of luminous AGN are massive elliptical galaxies, with scalelengths ~=10 kpc, and R-K colours consistent with mature stellar populations. Most importantly this is the the first unambiguous evidence that, just like radio-loud quasars, essentially all radio-quiet quasars brighter than M_R = -24 reside in massive ellipticals. This result removes the possibility that radio `loudness' is directly linked to host galaxy morphology, but is however in excellent accord with the black-hole/spheroid mass correlation recently highlighted by Magorrian et al. (1998). We apply the relations given by Magorrian et al. to infer the expected Eddington luminosity of the putative black hole at the centre of each of the spheroidal host galaxies we have uncovered. Comparison with the actual nuclear R-band luminosities suggests that the black holes in most of these galaxies are radiating at a few percent of the Eddington luminosity; the brightest host galaxies in our low-z sample are capable of hosting quasars with M_R = -28, comparable to the most luminous quasars at z = 3. Finally we discuss our host-derived black-hole masses in the context of the radio-luminosity:black-hole mass correlation recently uncovered for nearby galaxies by Franceschini et al. (1998), and the resulting implications for the physical origin of radio loudness.Comment: Submitted for publication in the Astrophysical Journal, 55 pages of latex, plus 12 postscript figures (Figures 1a-1s (greyscales of images and model fits, and Figures 2a-2g (luminosity profiles and model fits) can be downloaded from http://www.roe.ac.uk/astronomy/html/rjm1.shtml

Development of a strontium optical lattice clock for the SOC mission on the ISS

Ultra-precise optical clocks in space will allow new studies in fundamental physics and astronomy. Within an European Space Agency (ESA) program, the Space Optical Clocks (SOC) project aims to install and to operate an optical lattice clock on the International Space Station (ISS) towards the end of this decade. It would be a natural follow-on to the ACES mission, improving its performance by at least one order of magnitude. The payload is planned to include an optical lattice clock, as well as a frequency comb, a microwave link, and an optical link for comparisons of the ISS clock with ground clocks located in several countries and continents. Within the EU-FP7-SPACE-2010-1 project no. 263500, during the years 2011-2015 a compact, modular and robust strontium lattice optical clock demonstrator has been developed. Goal performance is a fractional frequency instability below 1x10^{-15}, tau^{-1/2} and a fractional inaccuracy below 5x10^{-17}. Here we describe the current status of the apparatus' development, including the laser subsystems. Robust preparation of cold {88}^Sr atoms in a second stage magneto-optical trap (MOT) is achieved.Comment: 27 Pages, 15 figures, Comptes Rendus Physique 201

Development of a strontium optical lattice clock for the SOC mission on the ISS

The ESA mission "Space Optical Clock" project aims at operating an optical lattice clock on the ISS in approximately 2023. The scientific goals of the mission are to perform tests of fundamental physics, to enable space-assisted relativistic geodesy and to intercompare optical clocks on the ground using microwave and optical links. The performance goal of the space clock is less than $1 \times 10^{-17}$ uncertainty and $1 \times 10^{-15} {\tau}^{-1/2}$ instability. Within an EU-FP7-funded project, a strontium optical lattice clock demonstrator has been developed. Goal performances are instability below $1 \times 10^{-15} {\tau}^{-1/2}$ and fractional inaccuracy $5 \times 10^{-17}$. For the design of the clock, techniques and approaches suitable for later space application are used, such as modular design, diode lasers, low power consumption subunits, and compact dimensions. The Sr clock apparatus is fully operational, and the clock transition in $^{88}$Sr was observed with linewidth as small as 9 Hz.Comment: 12 pages, 8 figures, SPIE Photonics Europe 201