17 research outputs found

    Chord-based Resource Identifier-to-Locator Mapping and Searching for the Future Internet

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    A great many problems, such as scalability, mapping data searching, high frequency update of mapping data, arise in the future network resource mapping system for its vast data processing need. Future Network Chord (FN Chord), an algorithm based on Chord and aims at solving the resources identity mapping and searching problem, is put forward by taking advantage of the qualities of scalability, rapid searching speed, high searching efficiency and flexible naming of chord in order to solve this problem. What’s more, an extra interest node index table for FN Chord is designed to record the hotspot resource mapping location in the paper. So, the resource searching strategy, which is named as Interest Index Table Future Network Chord (IIT-FN Chord) is proposed to search the resource in the paper. The entropy weight method is used to calculate the node interest level according the interest nodes’ resource item online time and visited times and to renew the interest index table. Moreover, probability replacement method is proposed to replace the outdated item on interest index table with new item. Simulation results show that the algorithm can decrease the average searching latency, average searching hops and thus increases the searching efficiency for the resource searching

    Polymer-based microring resonator with the multimode interference coupler operating at very-near-infrared wavelengths

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    A microring resonator with the multimode interference coupler is fabricated on the polymer platform by using UV-based soft nanoimprint technique. A unique class of fluorinated polymer, perfluoropolyether (PFPE), is employed for the fabrication of the flexible soft mold. By optimizing the proportion between Ormocore and the thinner maT, the microring resonator is fabricated almost without residual layer. The fabricated device with a Q-factor up to 2.3 × 104 is demonstrated for very-near-infrared wavelengths, which shows high potential for sensing applications

    Chronic Kidney Disease Increases Atrial Fibrillation Inducibility: Involvement of Inflammation, Atrial Fibrosis, and Connexins

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    Chronic kidney disease (CKD) causes atrial structural remodeling and subsequently increases the incidence of atrial fibrillation (AF). Atrial connexins and inflammatory responses may be involved in this remodeling process. In this study, nephrectomy was used to produce the CKD rat model. Three months post-nephrectomy, cardiac structure, function and AF vulnerability were quantified using echocardiography and electrophysiology methods. The left atrial tissue was tested for quantification of fibrosis and inflammation, and for the distribution and expression of connexin (Cx) 40 and Cx43. An echocardiography showed that CKD resulted in the left atrial enlargement and left ventricular hypertrophy, but had no functional changes. CKD caused a significant increase in the AF inducible rate (91.11% in CKD group vs. 6.67% in sham group, P < 0.001) and the AF duration [107 (0–770) s in CKD vs. 0 (0–70) s in sham, P < 0.001] with prolonged P-wave duration. CKD induced severe interstitial fibrosis, activated the transforming growth factor-β1/Smad2/3 pathway with a massive extracellular matrix deposition of collagen type I and α-smooth muscle actin, and matured the NLR (nucleotide-binding domain leucine-rich repeat-containing receptor) pyrin domain-containing protein 3 (NLRP3) inflammasome with an inflammatory cascade response. CKD resulted in an increase in non-phosphorylated-Cx43, a decrease in Cx40 and phosphorylated-Cx43, and lateralized the distribution of Cx40 and Cx43 proteins with upregulations of Rac-1, connective tissue growth factor and N-cadherin. These findings implicate the transforming growth factor-β1/Smad2/3, the NLRP3 inflammasome and the connexins as potential mediators of increased AF vulnerability in CKD

    Successful drug-eluting stent implantation in a male patient with dextrocardia: a case report

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    Situs inversus with dextrocardia is a rare condition, with complete transposition of all the body organs, including the heart. Percutaneous coronary intervention (PCI) in these patients is technically difficult because of the mirror image of organs. Here, we describe a 56-year-old man with coronary heart disease with known situs inversus with dextrocardia and coronary percutaneous intervention was performed for stenosis in the right coronary artery. A drug eluting stent was implanted at this site successfully. This case suggested that the interventional management of such patients follows the same general rules as for non-dextrocardia patients, but the manipulation of the catheter and projection position choices need to be taken into consideration to obtain optimal benefits for the patient
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