10 research outputs found
Perceptions of Active Learning between Faculty and Undergraduates: Differing Views among Departments
- Publication venue
- FHSU Scholars Repository
- Publication date
- 15/09/2016
- Field of study
There have been numerous calls recently to increase the use of active learning in university science, technology, engineering, and math (STEM) classrooms to more actively engage students and enhance student learning. However, few studies have investigated faculty and student perceptions regarding the effectiveness of active learning or the barriers to its implementation. Previous work surveying a single class in a single department has suggested that faculty and students have different perceptions of the effectiveness of active learning strategies and the barriers faculty face when implementing these teaching strategies. We expand on these previous findings by surveying a larger and more diverse sample of students and faculty in a college consisting of five departments. We find that students and faculty agree that active learning techniques are useful, effective, and should be implemented more widely, but disagree on the percentage of class time currently devoted to active learning. When we parsed the data by department, more nuanced perceptions became apparent. The perceived barriers to implementing teaching reform differed in importance by department and in some departments relatively few faculty had observed or used active learning. Our findings suggest that advocates of teaching reform must recognize that not all departments or institutions face the same barriers to implementing curricular changes
Roles matter: Graduate student perceptions of active learning in the STEM courses they take and those they teach
- Publication venue
- FHSU Scholars Repository
- Publication date
- 01/10/2021
- Field of study
Despite many calls to reform undergraduate science, technology, engineering, and math (STEM) education to incorporate active learning into classes, there has been little attention paid to graduate level classrooms or courses taught by graduate students. Here, we set out to understand if and how STEM graduate students’ perceptions of active learning change in the classes they take versus those they teach. We found that graduate students had taken relatively few graduate level classes using active learning and they felt that more time should be devoted to active learning in the courses they were taking. Teaching assistants felt that they were devoting the right amount of class time to active learning in the classes they taught. Graduate students also felt that they were using teaching methods in the classes they taught that were different from those they thought should be used when teaching undergraduates and were different from how they preferred to learn when taking classes
Finishing the euchromatic sequence of the human genome
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- Sutherland Robert D.
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- Wu Xiaojing
- Wu Zaining
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- Wycoff-Montenegro Melissa
- Wylie Kris
- Wyman Dudley
- Wyman Stacia
- Xi Yan
- Xi Yingying
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- Xie Gary
- Xie Jane
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- Xiong Yuqing
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- Yadav Shailendra
- Yakub Syed
- Yamamoto Lynn
- Yamamoto Noriko
- Yamamoto Yuko
- Yamashita Yasue
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- Yang Hao
- Yang Huanming
- Yang Huanming
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- Yao Zhijian
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- Yun Rui
- Zainoun Joanne
- Zembeck Lisa
- Zeng Yixin
- Zhai Dong
- Zhan Guoping
- Zhang Bo
- Zhang Caimin
- Zhang Fengmei
- Zhang Guangyu
- Zhang Guohua
- Zhang Guohua
- Zhang Haiqing
- Zhang Haiqing
- Zhang Haiqing
- Zhang Hongbo
- Zhang Hongbo
- Zhang Jingjing
- Zhang Jingjing
- Zhang Jingkun
- Zhang Jiuchun
- Zhang Jiuchun
- Zhang Lanzhi
- Zhang Li
- Zhang Li
- Zhang Meihua
- Zhang Meng
- Zhang Ming
- Zhang Qing
- Zhang Ruhua
- Zhang Shaojie
- Zhang Tiezhen
- Zhang Wei
- Zhang Wei
- Zhang Xianglin
- Zhang Xianglin
- Zhang Xiaoliang
- Zhang Xiuqing
- Zhang Yan
- Zhang Yi
- Zhang Yilin
- Zhang Yilin
- Zhang Ying
- Zhang Yuansen
- Zhang Yuzhi
- Zhang Zhengdong
- Zhao Hongmei
- Zhao Lijian
- Zhao Shenru
- Zhao Zhijing
- Zhen Zhicheng
- Zheng Haibo
- Zhong Ming
- Zhou Carol
- Zhou Haixia
- Zhou Jianling
- Zhou Nannan
- Zhou Xinfeng
- Zhou Yan
- Zhou Yang
- Zhou Yi
- Zhu Bingying
- Zhu Bofeng
- Zhu Fenghua
- Zhu Genfeng
- Zhu Genfeng
- Zhu Miao
- Zhu Ning
- Zhu Yongge
- Zhu Zhen
- Zhuang Shitao
- Zierten Deborah
- Zimmer Andrew
- Zody Michael C.
- Zollo Massimo
- Zorrilla Sara E.
- Zuo Lin
- Publication venue
- LSU Digital Commons
- Publication date
- 21/10/2004
- Field of study
The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead
Multiorgan MRI findings after hospitalisation with COVID-19 in the UK (C-MORE): a prospective, multicentre, observational cohort study
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- Abel K
- Adamali H.
- Adeloye D
- Adeyemi Oluwaseun
- Adrego Rita
- Aguilar Jimenez Laura A.
- Ahmad Haider N
- Ahmad Shanaz
- Ahmed R
- Ahwireng Nyarko
- Ainsworth Mark
- Al-Sheklly B.
- Alamoudi Asma
- Alfaro-Almagro Fidel
- Ali Mariam
- Aljaroof M
- Allan L
- Allen R J
- Allerton Lisa
- Allsop Lynne
- Allt Ann Marie
- Almeida Paula
- Altmann Danny
- Alvarez Corral Maria
- Amoils S.
- Anderson David
- Antoniades C
- Arbane Gill
- Arias Ava Maria
- Armour C.
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- Atkin Paul
- Aul Raminder
- Aung H
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- Avram Cristina
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- Wynter Inez
- Xie Cheng
- Xu M
- Yasmin Najira
- Yasmin S
- Yates Tom
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- Zawia Amira
- Zeidan Lisa
- Zhao Bang
- Zheng Bang
- Zongo O.
- Publication venue
- Elsevier
- Publication date
- 22/09/2023
- Field of study
Introduction:
The multiorgan impact of moderate to severe coronavirus infections in the post-acute phase is still poorly understood. We aimed to evaluate the excess burden of multiorgan abnormalities after hospitalisation with COVID-19, evaluate their determinants, and explore associations with patient-related outcome measures.
Methods:
In a prospective, UK-wide, multicentre MRI follow-up study (C-MORE), adults (aged ≥18 years) discharged from hospital following COVID-19 who were included in Tier 2 of the Post-hospitalisation COVID-19 study (PHOSP-COVID) and contemporary controls with no evidence of previous COVID-19 (SARS-CoV-2 nucleocapsid antibody negative) underwent multiorgan MRI (lungs, heart, brain, liver, and kidneys) with quantitative and qualitative assessment of images and clinical adjudication when relevant. Individuals with end-stage renal failure or contraindications to MRI were excluded. Participants also underwent detailed recording of symptoms, and physiological and biochemical tests. The primary outcome was the excess burden of multiorgan abnormalities (two or more organs) relative to controls, with further adjustments for potential confounders. The C-MORE study is ongoing and is registered with ClinicalTrials.gov, NCT04510025.
Findings:
Of 2710 participants in Tier 2 of PHOSP-COVID, 531 were recruited across 13 UK-wide C-MORE sites. After exclusions, 259 C-MORE patients (mean age 57 years [SD 12]; 158 [61%] male and 101 [39%] female) who were discharged from hospital with PCR-confirmed or clinically diagnosed COVID-19 between March 1, 2020, and Nov 1, 2021, and 52 non-COVID-19 controls from the community (mean age 49 years [SD 14]; 30 [58%] male and 22 [42%] female) were included in the analysis. Patients were assessed at a median of 5·0 months (IQR 4·2–6·3) after hospital discharge. Compared with non-COVID-19 controls, patients were older, living with more obesity, and had more comorbidities. Multiorgan abnormalities on MRI were more frequent in patients than in controls (157 [61%] of 259 vs 14 [27%] of 52; p<0·0001) and independently associated with COVID-19 status (odds ratio [OR] 2·9 [95% CI 1·5–5·8]; padjusted=0·0023) after adjusting for relevant confounders. Compared with controls, patients were more likely to have MRI evidence of lung abnormalities (p=0·0001; parenchymal abnormalities), brain abnormalities (p<0·0001; more white matter hyperintensities and regional brain volume reduction), and kidney abnormalities (p=0·014; lower medullary T1 and loss of corticomedullary differentiation), whereas cardiac and liver MRI abnormalities were similar between patients and controls. Patients with multiorgan abnormalities were older (difference in mean age 7 years [95% CI 4–10]; mean age of 59·8 years [SD 11·7] with multiorgan abnormalities vs mean age of 52·8 years [11·9] without multiorgan abnormalities; p<0·0001), more likely to have three or more comorbidities (OR 2·47 [1·32–4·82]; padjusted=0·0059), and more likely to have a more severe acute infection (acute CRP >5mg/L, OR 3·55 [1·23–11·88]; padjusted=0·025) than those without multiorgan abnormalities. Presence of lung MRI abnormalities was associated with a two-fold higher risk of chest tightness, and multiorgan MRI abnormalities were associated with severe and very severe persistent physical and mental health impairment (PHOSP-COVID symptom clusters) after hospitalisation.
Interpretation:
After hospitalisation for COVID-19, people are at risk of multiorgan abnormalities in the medium term. Our findings emphasise the need for proactive multidisciplinary care pathways, with the potential for imaging to guide surveillance frequency and therapeutic stratification
Mapping Free Speech Scholarship in the Communication Discipline: 1969–2006
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- Airne David J.
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- Amason Patricia
- Anderson Robert
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- Atkin David
- Attig R. Brian
- Aust Philip J
- Aust Philip J.
- Bailey Dennis L
- Bailey Dennis L.
- Bailey William
- Barbour Alton
- Barbour Alton
- Barbour Alton
- Barbour Alton
- Bassett John
- Beasley Maurine H.
- Benjamin Louise M.
- Benjamin Louise M.
- Bennett James R.
- Benson Thomas W.
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- Bosmajian Haig A.
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- Bowles Dorothy
- Brewer Edward C.
- Broussard E. Joseph
- Bubacz Bruce
- Buckrop Jacquelyn J.
- Bulsys Joseph A.
- Bumpers Dale
- Bunker Matthew
- Bunker Matthew
- Burgh James
- Bush Paul D.
- Cahill Corrine M.
- Casey Michael W.
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- Center Don B.
- Chafee Zachariah
- Chandler Daniel Ross
- Chandler Daniel Ross
- Chandler Daniel Ross
- Chang Hosoon
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- Chryslee Gail J.
- Chuang Rueyling
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- 'Informa UK Limited'
- Publication date
- Field of study
Identification of seven new prostate cancer susceptibility loci through a genome-wide association study
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- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2009
- Field of study
Prostate cancer (PrCa) is the most frequently diagnosed male cancer in developed countries. To identify common PrCa susceptibility alleles, we have previously conducted a genome-wide association study in which 541, 129 SNPs were genotyped in 1,854 PrCa cases with clinically detected disease and 1,894 controls. We have now evaluated promising associations in a second stage, in which we genotyped 43,671 SNPs in 3,650 PrCa cases and 3,940 controls, and a third stage, involving an additional 16,229 cases and 14,821 controls from 21 studies. In addition to previously identified loci, we identified a further seven new prostate cancer susceptibility loci on chromosomes 2, 4, 8, 11, and 22 (P=1.6×10−8 to P=2.7×10−33)
Cognitive and psychiatric symptom trajectories 2–3 years after hospital admission for COVID-19: a longitudinal, prospective cohort study in the UK
- Author
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- Zehra Suleiman (19671661)
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- Publication venue
- Publication date
- 31/07/2024
- Field of study
Background: COVID-19 is known to be associated with increased risks of cognitive and psychiatric outcomes after the acute phase of disease. We aimed to assess whether these symptoms can emerge or persist more than 1 year after hospitalisation for COVID-19, to identify which early aspects of COVID-19 illness predict longer-term symptoms, and to establish how these symptoms relate to occupational functioning. Methods: The Post-hospitalisation COVID-19 study (PHOSP-COVID) is a prospective, longitudinal cohort study of adults (aged ≥18 years) who were hospitalised with a clinical diagnosis of COVID-19 at participating National Health Service hospitals across the UK. In the C-Fog study, a subset of PHOSP-COVID participants who consented to be recontacted for other research were invited to complete a computerised cognitive assessment and clinical scales between 2 years and 3 years after hospital admission. Participants completed eight cognitive tasks, covering eight cognitive domains, from the Cognitron battery, in addition to the 9-item Patient Health Questionnaire for depression, the Generalised Anxiety Disorder 7-item scale, the Functional Assessment of Chronic Illness Therapy Fatigue Scale, and the 20-item Cognitive Change Index (CCI-20) questionnaire to assess subjective cognitive decline. We evaluated how the absolute risks of symptoms evolved between follow-ups at 6 months, 12 months, and 2–3 years, and whether symptoms at 2–3 years were predicted by earlier aspects of COVID-19 illness. Participants completed an occupation change questionnaire to establish whether their occupation or working status had changed and, if so, why. We assessed which symptoms at 2–3 years were associated with occupation change. People with lived experience were involved in the study. Findings: 2469 PHOSP-COVID participants were invited to participate in the C-Fog study, and 475 participants (191 [40·2%] females and 284 [59·8%] males; mean age 58·26 [SD 11·13] years) who were discharged from one of 83 hospitals provided data at the 2–3-year follow-up. Participants had worse cognitive scores than would be expected on the basis of their sociodemographic characteristics across all cognitive domains tested (average score 0·71 SD below the mean [IQR 0·16–1·04]; p<0·0001). Most participants reported at least mild depression (263 [74·5%] of 353), anxiety (189 [53·5%] of 353), fatigue (220 [62·3%] of 353), or subjective cognitive decline (184 [52·1%] of 353), and more than a fifth reported severe depression (79 [22·4%] of 353), fatigue (87 [24·6%] of 353), or subjective cognitive decline (88 [24·9%] of 353). Depression, anxiety, and fatigue were worse at 2–3 years than at 6 months or 12 months, with evidence of both worsening of existing symptoms and emergence of new symptoms. Symptoms at 2–3 years were not predicted by the severity of acute COVID-19 illness, but were strongly predicted by the degree of recovery at 6 months (explaining 35·0–48·8% of the variance in anxiety, depression, fatigue, and subjective cognitive decline); by a biocognitive profile linking acutely raised D-dimer relative to C-reactive protein with subjective cognitive deficits at 6 months (explaining 7·0–17·2% of the variance in anxiety, depression, fatigue, and subjective cognitive decline); and by anxiety, depression, fatigue, and subjective cognitive deficit at 6 months. Objective cognitive deficits at 2–3 years were not predicted by any of the factors tested, except for cognitive deficits at 6 months, explaining 10·6% of their variance. 95 of 353 participants (26·9% [95% CI 22·6–31·8]) reported occupational change, with poor health being the most common reason for this change. Occupation change was strongly and specifically associated with objective cognitive deficits (odds ratio [OR] 1·51 [95% CI 1·04–2·22] for every SD decrease in overall cognitive score) and subjective cognitive decline (OR 1·54 [1·21–1·98] for every point increase in CCI-20). Interpretation: Psychiatric and cognitive symptoms appear to increase over the first 2–3 years post-hospitalisation due to both worsening of symptoms already present at 6 months and emergence of new symptoms. New symptoms occur mostly in people with other symptoms already present at 6 months. Early identification and management of symptoms might therefore be an effective strategy to prevent later onset of a complex syndrome. Occupation change is common and associated mainly with objective and subjective cognitive deficits. Interventions to promote cognitive recovery or to prevent cognitive decline are therefore needed to limit the functional and economic impacts of COVID-19. Funding: National Institute for Health and Care Research Oxford Health Biomedical Research Centre, Wolfson Foundation, MQ Mental Health Research, MRC-UK Research and Innovation, and National Institute for Health and Care Research.</p
SYLLABUS AND BIBLIOGRAPHY FOR ISSUES IN FREEDOM OF SPEECH
- Author
- Abernathy M. Glenn
- Abernathy M. Glenn
- Abraham Henry J.
- Abraham Henry J.
- Anderson A.
- Anderson Walt
- Anshen Ruth N.
- Arnstein Walter L.
- Asch Sidney H.
- Asch Sidney H.
- Baade Hans W.
- Barker Lucius J.
- Barth Alan
- Bartholomew Paul C.
- Bayley David H.
- Bayne Stephen F.
- Bell Daniel
- Beman Lamar T.
- Berger Raoul
- Berns Walter F.
- Bickel Alexander M.
- Black Hugo
- Blanshard Paul
- Blumberg Abraham S.
- Bosmajian Haig
- Bosworth Allan R.
- Boyer Paul S.
- Boyle Kay
- Brant Irving
- Breckenridge Adam Carlyle
- Brown Oliver
- Brucker Herbert
- Buckley William F.
- Cahn Edmond
- Cantor Norman F.
- Capaldi Nicholas
- Carey John
- Carmen Ira H.
- Castberg Frede
- Caughey John W.
- Cavanah Frances
- Chafee Zechariah
- Chafee Zechariah
- Chafee Zechariah
- Chafee Zechariah
- Chafee Zechariah
- Chamberlain Lawrence H.
- Clark Ramsey
- Clor Harry M.
- Cohen William
- Cohen William
- Coil Henry W.
- Commager Henry Steele
- Commager Henry Steele
- Commager Henry Steele.
- Cox Archibald
- Crowther Bosley
- Curti Merle E.
- Cushman Robert S.
- Cushman Robert S.
- Cushman Robert S.
- Daniels Arlene Kaplan
- Daniels Walter Machray
- Dash Samuel
- de Alba Joaquin
- de Grazia Edward
- de Santillano Giorgio
- Dorsen Norman
- Dorsen Norman
- Douglas William O.
- Douglas William O.
- Douglas William O.
- Douglas William O.
- Dove Tom
- Dowden Wilfreds.
- Emerson Thomas I.
- Emerson Thomas I.
- Emerson Thomas I.
- Epstein Jason
- Ernst Morris
- Ernst Morris
- Ernst Morris
- Ernst Morris
- Fairman Charles
- Faulkner Robert Kenneth
- Fellman David
- Fellman David
- Fellman David
- Fernandez Benedict J.
- Finn James
- Fortas Abe
- Fraenkel Osmond
- Fraenkel Osmond
- Fribourg Marjorie G.
- Gardiner Harold C.
- Gardner David P.
- Gardner Fred
- Gelfand Ravina
- Gellhorn Walter
- Gertz Elmer
- Ginger Ann Fagan
- Girdner Audrie
- Goodman Walter
- Gordon William I.
- Graham Hugh Davis
- Grant Joanne
- Greenwalt Kent
- Grodzins Morton
- Gross Gerald
- Hachten William A.
- Haight Anne Lyon
- Haiman Franklyn S.
- Halstead Fred
- Handlin Oscar
- Haney Robert William
- Harris Richard
- Hart Herbert
- Hayden Thomas
- Hohenberg John
- Holmes Grace W.
- Holmes Oliver Wendall
- Holmes Oliver Wendall
- Hook Sidney
- Hook Sidney
- Howell Leon
- Hudon Edward G.
- Hunnings Neville M.
- Hunsaker David M.
- Hutchison E. R.
- Hyman Harold M.
- Hyman Harold M.
- Inglis Ruth
- Jackson Percival E.
- Jones Howard Mumford
- Joughin Louis
- Kalven Harry
- Kaplan Morton A.
- Kauper Paul G.
- Kennan George F.
- Kilpatrick James J.
- Kirk Russell
- Knight Harold V.
- Konvitz Milton R.
- Konvitz Milton R.
- Konvitz Milton R.
- Konvitz Milton R.
- Koop Theodore F.
- Krislov S.
- Kronhausen Eberhard
- Lacy Dan M.
- Lamont Corliss
- Lamont Corliss
- Laubach John H.
- Leigh Robert D.
- Levy Leonard W.
- Levy Leonard W.
- Levy Leonard W.
- Levy Leonard W.
- Levy Leonard W.
- Lofton John
- Longaker Richard P.
- Ludwig Bernard
- Lynd Staughton
- Lytle Clifford M.
- Mailer Norman
- Manier August Edward
- Mason Alpheus T.
- Mayer Martin
- Mayer Milton
- McClellan Grant
- McCoy Ralph E.
- McGaffin William
- Meiklejohn Alexander
- Meiklejohn Alexander
- Meiklejohn Donald
- Mendelson Wallace
- Metzger Walter P.
- Mill John Stuart
- Miller Charles A.
- Miller Helen Hill
- Miller James C.
- Miller Leonard G.
- Millett John D.
- Mitford Jessica
- Moon Eric
- Moos M.
- Morison Samuel Eliot
- Nelson Harold L.
- Newman EdwinS.
- O'Neil Robert M.
- Parker Donald
- Paul James C. N.
- Pfeffer Leo
- Phelan John
- Popper William
- Preston William
- Pride Armistead
- Pritchett Charles H.
- Rader Melvin
- Rahner Karl
- Randall Richard
- Rankin Robert S.
- Ransom Harry Howe
- Rapoport Roger
- Reitman Alan
- Rembar Charles
- Rhodes Irwin S.
- Rice Charles E.
- Rice George P.
- Rice George P.
- Rice George P.
- Rivers William Lawrence
- Roberts Moira
- Roche John P.
- Rose Arnold M.
- Rosenberg Jerry M.
- Rucker Bryce W.
- Sacco Nicola
- Sayler Richard
- Schapsmeier Edward L.
- Schlesinger Arthur M.
- Schroeder Theodore
- Schroeder Theodore
- Schroeder Theodore
- Schumach Murray
- Scopes John T.
- Shapiro Martin
- Shikes Ralph E.
- Skolnich Jerome H.
- Smith James M.
- Smith Robert
- Sobul DeAnne
- Sowle Claude R.
- Stein Meyer L.
- Stevick Daniel B.
- Stewart George Rippey
- Stouffer Samuel A.
- Summers Marvin
- Summers Robert E.
- Sweet Esther C.
- Tedford Thomas L.
- Ten Broek Jacobus
- Thayer Frank
- Thomas Dorothy S.
- Tresolini Rocco J.
- Urofsky Melvin
- Wahlke John C.
- Walker Daniel
- Waskow Arthur I.
- Watkins Arthur V.
- Way H. Frank
- Weaver Gary R.
- Weissman Harold H.
- Wiggins James R.
- Wilcox Clair
- Williamson Edmund G.
- Young Alfred F.
- Zarr Melvyn
- Zinn Howard
- Publication venue
- 'Informa UK Limited'
- Publication date
- Field of study