Interplay of Fantasy and Realism in Salman Rushdie’s Midnight’s Children

Fantasy and realism are the traits to be found in every culture and individual. Fantasy was often dismissed for being a thing associated with children. This was a practice found to be rampant in the past or it was rather a matter of the past so to say. After centuries of oblivion, people have started giving importance to fantasy when there is a lot of chaos in the society. Fantasy as a genre that helps us to band together, explain, change and form an opinion on reality. Fantasy can surely tempt the human desire, for more than the familiar world of the readers, into ease, anyway from reality and communicate with immense imagination that the readers can connect to. With this in mind, the paper tries to analyze Rushdie’s Midnight’s Children the bizarre and the fantastic blurs the boundaries between the real and plausible in the novel, thereby problematizing the identities of gender, parenthood, and nationality, and renders the readers into a state of uncertainty by incorporating oblique references or links. It also aims to critically analyze and discuss how the lines between fantasy and reality are blurred in literature. The importance of this study is to connect the fine line of fantasy with reality in literature and to present perceptions to the readers on how literature is understood differently by different people

Differential game model and coordination model for green supply chain based on green technology research and development

The purpose of this paper is to establish a green supply chain differential game model for green technology research and development based on a secondary green supply chain composed of a single manufacturer and a single retailer. It compares the differential game equilibrium solutions under centralized and decentralized decision-making. The green supply chain members are coordinated through the dynamic wholesale price mechanism, and numerical simulation is used as a methodology, to verify and explain the results. The study found that compared to decentralized decision-making, the level of green technology and the total profit of green channels are higher under centralized decision-making. When the coordination parameters are within a certain range, the dynamic wholesale price mechanism can coordinate the behavior of manufacturers and retailers. The result also discovers that under the dynamic wholesale price mechanism, with the increase of investment cost coefficient, or the increase of price sensitivity or the decrease of consumer's environmental awareness, the green technology level, product green degree, price, retailer's profit, and the total profit of green channel is decreased. In contrast, the wholesale price and manufacturer's profits are increased

Study of Thyristor Controlled Series Capacitor (TCSC) as a useful FACTS Device

For transmission of large amounts of electric power, AC in the overwhelming majority of cases is the established as well as the most cost effective option at hand. In cases of long distance transmission, as in interconnection of power systems, care has to be taken for safeguarding of synchronism as well as stable system voltages in the interconnection, particularly for extreme load conditions and in conjunction with system faults. Use of Thyristor Controlled Series Capacitor (TCSC) as Flexible AC Transmission System (FACTS) device brings a number of benefits for the user of the grid, all contributing to an increase of the power transmission capability of new as well as existing transmission lines. These benefits include improvement in system stability, voltage regulation, reactive power balance, load sharing between parallel lines and reduction in transmission losses

Electrical conductivity retention and electrochemical activity of CSA doped graphene/gold nanoparticle@ polyaniline composites

AbstractThis paper reports the synthesis of CTAB mediated CSA doped PANI and GN/GNP@ PANI composite nanofibers. The as synthesized composite nanofibers were examined by TEM, SEM, XRD, Raman spectroscopy; UV–visible diffused reflectance spectroscopy and TGA. The CTAB mediated CSA doped composite nanofibers showed 59% higher DC electrical conductivity at ambient temperature than that of PANI, which might be due to the enhancement in the mobility of the charge carriers and reduction in hopping distance in the composite system. The CTAB mediated CSA doped composite nanofibers compared to PANI was observed to be showing enhanced DC electrical conductivity retention after various cycles of heating, suggesting an enhancement in thermal stability of the composite structure, which could be attributed to the synergistic effect of GN, GNP and PANI. Additionally, the composite nanofibers showed greater electrochemical activity and better capacitive performance and reduced optical bandgap than that of PANI

An advanced architecture & instrumentation for developing the system of monitoring a vital sign (Oxygen Saturation) of a patient

Bio-Medical Engineering (BME) has been an active research area for years. BME is the application of engineering techniques to the medical fields. It combines the design and problem solving skills of engineering with medical sciences to improve the health care and the quality of individual life. With the proliferation of advanced electronics and applied engineering, the ways to help people specifically patients are changed. Therefore, an advanced design for monitoring a vital sign towards experimentation is presented. The vital signs monitor is essentially a real time device that displays certain received signals from the human body. The projects of this sort under taken so far have used windows to display the output whereas this project aims to generate a real time display of the signals received from the human body using Linux. Linux was preferred for its ability to simultaneously process data and display it in real time. The basic principles and methods are outlined. The major components of the system are shown separately, and are discussed individually. Few electronic devices used for data are depicted and described. The final results show a better performance

Exploring knowledge and practices regarding menstrual hygiene management among Bihari women in the Geneva Camp in Bangladesh

Background: Research into menstrual hygiene management (MHM) has been mainly based on menstruation-related knowledge and practices of women and girls in the mainstream Bangladeshi society; socially disadvantaged groups, such as the Bihari refugee women, have largely been ignored. Purpose: This study aims to assess knowledge and practices about MHM among Bihari women in the Mohammadpur Geneva Camp in Dhaka, Bangladesh. Methods: In 2017, a cross-sectional survey was conducted among Bihari women and girls by the trained interviewers using a structured questionnaire. The purposive sampling was applied to select 160 Bihari women aged between 15 and 49. Data were entered, cleaned, and analysed using SPSS software. Both univariate and bivariate analyses were undertaken to examine knowledge and MHM-related practices with a significance level of p<0.01. Results: Overall, most women (59.4%) had low knowledge about menstruation. More than one-quarter (27.0%) used disposable sanitary napkins. The Bihari women who did not use sanitary pads (73%) reported that they used old disposable clothes (59.83%), reusable cloths (25.64%), cotton (9.40%), or toilet tissue paper (4.27%). Around two-thirds of the women (68.0%) performed special baths and 36.9% followed socio-cultural taboos during menstruation. The bivariate analyses revealed that higher menstruation knowledge was associated with higher use of disposable sanitary napkins (low knowledge: 18.9%, high knowledge: 38.5%; p<0.01). Conclusions: The findings suggest that it is imperative for Bihari women to have adequate and appropriate menstruation knowledge so that they can maintain good menstrual hygiene practices. The findings highlight challenges experienced by the refugee women in maintaining MHM and can be used to improve women’s reproductive health and well-being and reduce the risk of reproductive tract infections (RTI) among socially disadvantaged women

Surface Elevation and Sedimentation Dynamics in the Ganges-Brahmaputra Tidal Delta Plain, Bangladesh: Evidence for Mangrove Adaptation to Human-Induced Tidal Amplification

In the Ganges-Brahmaputra (G-B) delta, periodic flooding of the land surface during the tidal cycle coupled with enormous sediment delivery during the monsoon promotes sediment accretion and surface elevation gain through time. However, over the past several decades, widespread embankment (“polder”) construction in the GB tidal delta plain has led to numerous environmental disturbances, including channel siltation and tide range amplification. While previous research indicates that rates of sediment accretion are relatively high in the G-B tidal delta plain, it remains unclear if and how surface elevation is maintaining pace with relative sea-level rise (RSLR) in this region. In this study, we utilize an array of surface elevation tables, sediment traps, and groundwater piezometers to provide longitudinal trends of sedimentation and elevation dynamics with respect to local platform elevation and associated hydroperiod. Two hydro-geomorphic settings of the Sundarbans mangrove forest are compared: higher elevation stream-bank and lower elevation interior. Seasonal measurements over a time span of 5 years reveal that elevation gain is occurring in all settings, with the highest rates observed at elevated stream-bank zones. Elevation gain occurs primarily in response to sediment accretion, with possible minor contributions from pore-water storage and swelling of clay minerals during the monsoon season (i.e., belowground biomass and organic contribution is minimal). As a result, elevation loss and shallow subsidence in the G-B delta is unlikely to be caused by compaction of organic-rich soils, but rather appears to be controlled by seasonal lowering of the groundwater table and compaction of clay minerals. Rates of surface elevation gain in the Sundarbans greatly exceed rates of RSLR and more closely follow rates of RSLR augmented from tide range amplification, indicating that this landscape is adapting to human-induced environmental change. The proceedings of this study underscore the adaptability of the natural G-B tidal delta plain to local environmental disturbances, with the caveat that these defenses may be lost to future upstream reductions in sediment supply

[6]-Gingerol, from Zingiber officinale, potentiates GLP-1 mediated glucose-stimulated insulin secretion pathway in pancreatic β-cells and increases RAB8/RAB10-regulated membrane presentation of GLUT4 transporters in skeletal muscle to improve hyperglycemia in Leprdb/db type 2 diabetic mice

This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.Abstract Background [6]-Gingerol, a major component of Zingiber officinale, was previously reported to ameliorate hyperglycemia in type 2 diabetic mice. Endocrine signaling is involved in insulin secretion and is perturbed in db/db Type-2 diabetic mice. [6]-Gingerol was reported to restore the disrupted endocrine signaling in rodents. In this current study on Leprdb/db diabetic mice, we investigated the involvement of endocrine pathway in the insulin secretagogue activity of [6]-Gingerol and the mechanism(s) through which [6]-Gingerol ameliorates hyperglycemia. Methods Leprdb/db type 2 diabetic mice were orally administered a daily dose of [6]-Gingerol (200 mg/kg) for 28 days. We measured the plasma levels of different endocrine hormones in fasting and fed conditions. GLP-1 levels were modulated using pharmacological approaches, and cAMP/PKA pathway for insulin secretion was assessed by qRT-PCR and ELISA in isolated pancreatic islets. Total skeletal muscle and its membrane fractions were used to measure glycogen synthase 1 level and Glut4 expression and protein levels. Results 4-weeks treatment of [6]-Gingerol dramatically increased glucose-stimulated insulin secretion and improved glucose tolerance. Plasma GLP-1 was found to be significantly elevated in the treated mice. Pharmacological intervention of GLP-1 levels regulated the effect of [6]-Gingerol on insulin secretion. Mechanistically, [6]-Gingerol treatment upregulated and activated cAMP, PKA, and CREB in the pancreatic islets, which are critical components of GLP-1-mediated insulin secretion pathway. [6]-Gingerol upregulated both Rab27a GTPase and its effector protein Slp4-a expression in isolated islets, which regulates the exocytosis of insulin-containing dense-core granules. [6]-Gingerol treatment improved skeletal glycogen storage by increased glycogen synthase 1 activity. Additionally, GLUT4 transporters were highly abundant in the membrane of the skeletal myocytes, which could be explained by the increased expression of Rab8 and Rab10 GTPases that are responsible for GLUT4 vesicle fusion to the membrane. Conclusions Collectively, our study reports that GLP-1 mediates the insulinotropic activity of [6]-Gingerol, and [6]-Gingerol treatment facilitates glucose disposal in skeletal muscles through increased activity of glycogen synthase 1 and enhanced cell surface presentation of GLUT4 transporters

Efficacy and Safety of Methotrexate in Articular and Cutaneous Manifestations of systemic Lupus Erythematosus

Aim:  A prospective open-label study comparing the efficacy and safety of methotrexate (MTX) and chloroquine (CQ) in articular and cutaneous manifestations of systemic lupus erythematosus (SLE). Methods:  Consecutive SLE patients were randomly assigned to either 10 mg MTX weekly or 150 mg CQ daily during 24 weeks. Outcome measures were: numbers of swollen and tender joints, duration of morning stiffness, visual analog scale (VAS) for articular pain, physician global assessment index, patient global assessment index, SLE Disease Activity Index (SLEDAI), disappearance of skin rash and erythrocyte sedimentation rate (ESR). Results:  Forty-one patients consented to participate, 15 were allocated in the MTX group and 26 in the CQ group. Two patients on MTX dropped out due to side-effects and two in the CQ group, one due to side-effects and one due to inefficacy. Baseline demographic, clinical and laboratory parameters of the two groups were nearly identical. In both groups the clinical and laboratory parameters improved significantly over 24 weeks, except the ESR in the MTX group. The results of the outcome measures at the end of the trial did not differ significantly between the two groups, except morning stiffness (P < 0.05 in favor of the MTX group) and ESR (P < 0.01 in favor of the CQ group). Rise of serum alanine aminotransferase was observed in two cases in the MTX group and in none in the CQ group. Conclusion:  Low-dose MTX appears to be as effective as CQ in patients with articular and cutaneous manifestations of SLE, having an acceptable toxicity profile. Results of this prospective study need to be confirmed in a larger study

Municipal wastewater can result in a dramatic decline in freshwater fishes: a lesson from a developing country

Impacts of ineffective wastewater management on the biodiversity of receiving waters in developing countries are poorly documented. Using a before-after-control-impact methodology, we measured the effects of untreated wastewater release on the fish community in the Barnoi River, Bangladesh. In 2006, prior to untreated wastewater discharge, fish abundance, species richness and water quality were similar across sampling sites. In 2016, after 8 years of wastewater release to the downstream reach, fish abundance and species richness were reduced by >47% and >35% respectively at downstream sites compared to unaffected upstream sites and >51% and >41% lower respectively compared to the pre-wastewater discharge period. The wastewater impact was particularly severe during months of low discharge (October–December). Water transparency, dissolved oxygen and pH were lower (P < 0.001) at impacted downstream sites compared to upstream sites. Nineteen species (41.3% of all species we recorded) are threatened in Bangladesh and the abundance of these species, except one, decreased significantly (P < 0.05) at the impacted sites. We recommend improved wastewater management by applying primary treatment facilities and incorporating reedbed filtration as a mean of biological treatment, into the canals carrying wastewaters. The success of such measures should be tested with fish species that were most responsive to wastewater, using the indicator species concept