116 research outputs found

    Core Equivalence in Economy under Generalized Information

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    We investigate a pure exchange atomless economy under uncertainty with emphasis on an epistemic point of view, where the traders are assumed to have a non-partitional information structure. We propose a generalized notion of rational expectations equilibrium for the economy and we show the core equivalence theorem: The ex-post core for the economy coincides with the set of all its rational expectations equilibria.Pure exchange economy under refexive information structure, Ex-post core, Rational expectations equilibrium, Core equivalence theorem

    Suppression of 12-O-tetradecanoylphorbol-13-acetate-induced ornithine decarboxylase activity by resveratrol derivatives

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    As demonstrated previously, resveratrol (3,4',5-trihydroxy-trans-stilbene) inhibits 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced ornithine decarboxylase (ODC), the key rate limiting enzyme in mammalian polyamine synthesis. Using human bladder epithelial carcinoma HTB-24 cells in culture where resveratrol inhibits induction with an IC50 of 8.8 µM, we now report potential metabolites demonstrate greater activity [tetrabutylammonium (E)-4-(3,5-dihydroxystyryl)phenyl sulfate (IC50 1.2 µM), resveratrol tripotassium 3,5,4'-trisulfate (IC50 1.8 µM), resveratrol tripotassium 3,4'-disulfate (IC50 1.8 µM), and resveratrol tripotassium 3,5-disulfate (IC50 2.3 µM)]. Based on RT-PCR studies, ODC inhibition occurs at the transcriptional level, but this was not due to direct inhibition of protein kinase C (e.g., resveratrol IC50, 79 µM; resveratrol tripotassium 3,5-disulfate IC50, 49 µM). Additional work is underway to more fully investigate this potentially important observation. [This work was supported by program project P01 CA48112 awarded by the National Cancer Institute. SL acknowledges Indo-US Science and Technology Forum (IUSSTF), New Delhi for a Research Fellowship]

    Complex sequencing rules of birdsong can be explained by simple hidden Markov processes

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    Complex sequencing rules observed in birdsongs provide an opportunity to investigate the neural mechanism for generating complex sequential behaviors. To relate the findings from studying birdsongs to other sequential behaviors, it is crucial to characterize the statistical properties of the sequencing rules in birdsongs. However, the properties of the sequencing rules in birdsongs have not yet been fully addressed. In this study, we investigate the statistical propertiesof the complex birdsong of the Bengalese finch (Lonchura striata var. domestica). Based on manual-annotated syllable sequences, we first show that there are significant higher-order context dependencies in Bengalese finch songs, that is, which syllable appears next depends on more than one previous syllable. This property is shared with other complex sequential behaviors. We then analyze acoustic features of the song and show that higher-order context dependencies can be explained using first-order hidden state transition dynamics with redundant hidden states. This model corresponds to hidden Markov models (HMMs), well known statistical models with a large range of application for time series modeling. The song annotation with these models with first-order hidden state dynamics agreed well with manual annotation, the score was comparable to that of a second-order HMM, and surpassed the zeroth-order model (the Gaussian mixture model (GMM)), which does not use context information. Our results imply that the hierarchical representation with hidden state dynamics may underlie the neural implementation for generating complex sequences with higher-order dependencies

    Enhanced stability of layered phases in parallel hard-spherocylinders due to the addition of hard spheres

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    There is increasing evidence that entropy can induce microphase separation in binary fluid mixtures interacting through hard particle potentials. One such phase consists of alternating two dimensional liquid-like layers of rods and spheres. We study the transition from a uniform miscible state to this ordered state using computer simulations and compare results to experiments and theory. We conclude that (1) there is stable entropy driven microphase separation in mixtures of parallel rods and spheres, (2) adding spheres smaller then the rod length decreases the total volume fraction needed for the formation of a layered phase, therefore small spheres effectively stabilize the layered phase; the opposite is true for large spheres and (3) the degree of this stabilization increases with increasing rod length.Comment: 11 pages, 9 figures. Submitted to Phys. Rev. E. See related website http://www.elsie.brandeis.ed

    A compact statistical model of the song syntax in Bengalese finch

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    Songs of many songbird species consist of variable sequences of a finite number of syllables. A common approach for characterizing the syntax of these complex syllable sequences is to use transition probabilities between the syllables. This is equivalent to the Markov model, in which each syllable is associated with one state, and the transition probabilities between the states do not depend on the state transition history. Here we analyze the song syntax in a Bengalese finch. We show that the Markov model fails to capture the statistical properties of the syllable sequences. Instead, a state transition model that accurately describes the statistics of the syllable sequences includes adaptation of the self-transition probabilities when states are repeatedly revisited, and allows associations of more than one state to the same syllable. Such a model does not increase the model complexity significantly. Mathematically, the model is a partially observable Markov model with adaptation (POMMA). The success of the POMMA supports the branching chain network hypothesis of how syntax is controlled within the premotor song nucleus HVC, and suggests that adaptation and many-to-one mapping from neural substrates to syllables are important features of the neural control of complex song syntax

    短大生の食生活

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    A dietary survey was made on 90 students of a dietitian training junior college about their dietary habits, especially the number of daily meal times and contents of meal during one week. 1. Number of students without taking breakfast was larger than those without lunch or supper. 2. Frequency of eating-cut was mostly observed in the case of lunch, and the number was about 11% of the total number of lunch. 3. As the staple food, cooked rice was taken more frequently, about 60%, than bread, which was taken about 20%.Bread was more taken as breakfast than as lunch or supper. 4. As the food material for the main dish, meat was used mostly, beyond 30%, and next to meat, shellfish, eggs, soybean products were used in this order. 5. As convenience foods, soup and Chinese noodles were most frequently used. 6. Total frequency of taking ready-to-serve food, ready-to-cook food, or retort pouch food was about 1 - 3%

    Phase behaviour and gravity-directed self assembly of hard convex spherical caps

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    We investigate the phase behaviour and self-assembly of convex spherical caps using Monte Carlo simulations. This model is used to represent the main features observed in experimental colloidal particles with mushroom-cap shape [Riley et al., Langmuir, 2010, 26, 1648]. The geometry of this non-centrosymmetric convex model is fully characterized by the aspect ratio χ∗ defined as the spherical cap height to diameter ratio. We use NPT Monte Carlo simulations combined with free energy calculations to determine the most stable crystal structures and the phase behaviour of convex spherical caps with different aspect ratios. We find a variety of crystal structures at each aspect ratio, including plastic and dimer-based crystals; small differences in chemical potential between the structures with similar morphology suggest that convex spherical caps have the tendency to form polycrystalline phases rather than crystallising into a single uniform structure. With the exception of plastic crystals observed at large aspect ratios (χ∗ > 0.75), crystallisation kinetics seem to be too slow, hindering the spontaneous formation of ordered structures. As an alternative, we also present a study of directing the self-assembly of convex spherical caps via sedimentation onto solid substrates. This study contributes to show how small changes to particle shape can significantly alter the self-assembly of crystal structures, and how a simple gravity field and a template can substantially enhance the process
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