Guest Artist Series:Maria Horvath, Piano

Center for the Performing Arts Monday Evening January 26, 2004 8:00p.m

Guest Artist Maria Horvath, Piano

Kemp Recital Hall Monday Evening February 15, 1999 8:00p.m

Graduate Recital: Maria Horvath, Piano

Kemp Recital Hall Saturday Afternoon April 24, 1993 4:30p.m

Dr. Maria Horvath, Fortepiano Masterclass

Kemp Recital Hall September 30, 2018 Sunday Afternoon 4:00 p.m

Volumes Three and Four of Jozsef Soproni\u27s Note Pages : A Stylistic Study.

Jozsef Soproni, born in Hungary in 1930, composed in virtually every genre of musical composition: symphonies, other orchestral pieces, concertos, an opera, masses, cantatas, other choral pieces, songs, string quartets, sonatas, plus other chamber and instrumental pieces. His interest in solo piano music is realized in a number of compositions written before 1979 and his twelve piano sonatas written between 1996 and the first quarter of 1999. There is no comprehensive study of Soproni\u27s music for piano; indeed all that has been published about it are brief analyses of various pieces, biographical sketches in books, and two articles in a Hungarian pedagogical journal of music. Note Pages includes eighty pieces for solo piano in four volumes, composed in 1974, 1975, 1977, and 1978. While volume 1 consists of short pieces and the consecutive volumes contain an increasing number of longer and more challenging compositions, Note Pages is a collection of performance pieces for pianists on various levels rather than being a didactic work. This monograph examines the fifteen pieces in volumes 3 and 4. Chapter 1 includes biographical information and an overview of Soproni\u27s musical heritage and aesthetics, his works, his compositions for solo piano, and the entire collection of Note Pages. Chapters 2 and 3 examine the third and fourth volumes of the work, with emphasis on compositional techniques and pianism. The study concludes with a brief summary of stylistic features found in the last two volumes and possible difficulties encountered by the performer, as well as some advice given by the composer regarding the preparation process preceding performance as well as the main objectives of a good performance of these pieces

Prevalence of Heart Disease Risk Factors in the Azores

Abstract(157) de Comunicação em Painel apresentada em "81st European Atherosclerosis Society (AES) Congress", 2013, 2-5 Jun, Lyon, France.BACKGROUND and AIMS: In the Azores age adjusted death rates from coronary heart disease (CHD) are two-fold higher than in mainland Portugal. We determined the prevalence of standard and emerging CHD risk factors in 206 female and 146 male Azorean subjects (mean age 41 years)

Analysis for co-occurring sequence features identifies link between common synonymous variant and an early-terminated NPC1 isoform

Direct assessment of allelic phase for DNA and RNA features of diploid genomes has been challenging for Sanger sequencing, due to its allele-conflating base-calling signal. Massively parallel sequencing technologies are based on the generation of a continuous copy of a single strand sequence segments, thus preserving the allelic relation between the features of the original molecules. We have performed a transcriptome-wide search for co-occurrence of variant nucleotides and exon-intron boundaries positioned within the length of a single sequencing read. Analysis of 75 human transcriptomes from retinal pigment epithelia (RPE), glioblastoma, low-grade brain tumor, breast cancer and colon cancer, have identified an association between the synonymous variant rs1140458 and an early-terminated NPC1 isoform lacking exons 19–25. Higher proportion of molecules bearing the variant nucleotide (versus the reference) incorporates the intron (P \u3c0.0001), which turns the last codon of exon 18 into a stop codon. The significance is highest in RPE cells (P = 3.88 × 10−12). NPC1 protein is involved in the control of the cholesterol trafficking. NPC1 mutations lead, in an autosomal recessive manner, to the neurological disorder Niemann-Pick syndrome type C (NP-C), and, ablation of NPC1 causes age-progressive retinal degeneration in mice and drosophila. The vast majority of the NP-C causative variants consist of missense/nonsense substitutions, small indels, and, intronic splice variants. Rs1140458 is a common exonic synonymous substitution that has never been linked to alternative splicing or pathogenicity. Our analysis suggests that rs1140458 may affect the levels of the functional NPC1 protein, and to contribute to some of the cholesterol-implicated cellular phenotype

3D-Cell-Annotator : an open-source active surface tool for single-cell segmentation in 3D microscopy images

aSummary: Segmentation of single cells in microscopy images is one of the major challenges in computational biology. It is the first step of most bioimage analysis tasks, and essential to create training sets for more advanced deep learning approaches. Here, we propose 3D-Cell-Annotator to solve this task using 3D active surfaces together with shape descriptors as prior information in a semi-automated fashion. The software uses the convenient 3D interface of the widely used Medical Imaging Interaction Toolkit (MITK). Results on 3D biological structures (e.g. spheroids, organoids and embryos) show that the precision of the segmentation reaches the level of a human expert.Peer reviewe