Nonmonotonic Evolution of the Blocking Temperature in Dispersions of Superparamagnetic Nanoparticles

We use a Monte Carlo approach to simulate the influence of the dipolar interaction on assemblies of monodisperse superparamagnetic ${\gamma}-Fe_{2}O_{3}$ nanoparticles. We have identified a critical concentration c*, that marks the transition between two different regimes in the evolution of the blocking temperature ($T_{B}$) with interparticle interactions. At low concentrations (c < c*) magnetic particles behave as an ideal non-interacting system with a constant $T_{B}$. At concentrations c > c* the dipolar energy enhances the anisotropic energy barrier and $T_{B}$ increases with increasing c, so that a larger temperature is required to reach the superparamagnetic state. The fitting of our results with classical particle models and experiments supports the existence of two differentiated regimes. Our data could help to understand apparently contradictory results from the literature.Comment: 13 pages, 7 figure

Experimental Verification of Surface Vehicle Dynamics

Experimental verification of surface vehicle dynamic

A Rapid Method for Observing the Internal Morphology of Amphibian Embryos

A simple, rapid method for visualizing the internal morphology of amphibian embryos is described. Fixed embryos of Ambystoma mexicanum are surrounded with commercial embedding material and are frozen. Internal structure is revealed by cutting the embryos with a cooled scalpel or razor blade, removing the frozen embedment with an aqueous buffer, and processing the halved embryos for scanning electron microscopy (SEM). This technique allows the internal anatomy of the embryo to be viewed but is much simpler and more rapid than previously described techniques. It should therefore prove useful for understanding and teaching the three-dimensional relationship between tissues in developing embryos. In addition, we believe that this technique could be used, with minor changes, as a rapid method for viewing the internal morphology of a variety of specimens

Homozygous disruption of P450 side-chain cleavage (CYP11A1) is associated with prematurity, complete 46,XY sex reversal, and severe adrenal failure

Disruption of the P450 side-chain cleavage cytochrome (P450scc) enzyme due to deleterious mutations of the CYP11A1 gene is thought to be incompatible with fetal survival because of impaired progesterone production by the fetoplacental unit. We present a 46, XY patient with a homozygous disruption of CYP11A1.The child was born prematurely with complete sex reversal and severe adrenal insufficiency. Laboratory data showed diminished or absent steroidogenesis in all pathways. Molecular genetic analysis of the CYP11A1 gene revealed a homozygous single nucleotide deletion leading to a premature termination at codon position 288. This mutation will delete highly conserved regions of the P450scc enzyme and thus is predicted to lead to a nonfunctional protein. Both healthy parents were heterozygous for this mutation.Our report demonstrates that severe disruption of P450scc can be compatible with survival in rare instances. Furthermore, defects in this enzyme are inherited in an autosomal-recessive fashion, and heterozygote carriers can be healthy and fertile. The possibility of P450scc-independent pathways of steroid synthesis in addition to the current concept of luteoplacental shift of progesterone synthesis in humans has to be questioned

Correlated Microscale Isotope and Scanning Transmission X-Ray Analyses of Isotopically Anomalous Organic Matter from the CR2 Chondrite EET 92042

We discuss correlated examinations of organic matter from the CR2 chondrite EET 92042, using SIMS, STXM and other methods. We found a large, isotopically highly anomalous region of probable presolar origin that is C- and 13C-poor and 15N-rich

Hamiltonian dynamics of extended objects

We consider a relativistic extended object described by a reparametrization invariant local action that depends on the extrinsic curvature of the worldvolume swept out by the object as it evolves. We provide a Hamiltonian formulation of the dynamics of such higher derivative models which is motivated by the ADM formulation of general relativity. The canonical momenta are identified by looking at boundary behavior under small deformations of the action; the relationship between the momentum conjugate to the embedding functions and the conserved momentum density is established. The canonical Hamiltonian is constructed explicitly; the constraints on the phase space, both primary and secondary, are identified and the role they play in the theory described. The multipliers implementing the primary constraints are identified in terms of the ADM lapse and shift variables and Hamilton's equations shown to be consistent with the Euler-Lagrange equations.Comment: 24 pages, late

Instanton bundles on Fano threefolds

We introduce the notion of an instanton bundle on a Fano threefold of index 2. For such bundles we give an analogue of a monadic description and discuss the curve of jumping lines. The cases of threefolds of degree 5 and 4 are considered in a greater detail.Comment: 31 page, to appear in CEJ

Venous Leak Embolization in Patients with Venogenic Erectile Dysfunction via Deep Dorsal Penile Vein Access: Safety and Early Efficacy.

PURPOSE This all-comers registry aimed to assess safety and early efficacy of venous embolization in patients with venogenic erectile dysfunction due to venous leak in an unselected cohort. METHODS Between October 2019 and September 2022, patients with venogenic erectile dysfunction resistant to phosphodiesterase-5-inhibitors were treated with venous embolization using ultrasound-guided anterograde access via a deep dorsal penile vein in a single center. A mix of ethiodized oil and modified cyanoacrylate-based glue n-butyl 2 cyanoacrylate (NBCA) monomer plus methacryloxy-sulpholane monomer (Glubran-2, GEM, Italy) was used as liquid embolic agent. Prior to embolization, venous leak had been verified based on penile duplex sonography and computed tomography cavernosography. Procedural success was defined as technically successful and complete target vein embolization. The primary safety outcome measure was any major adverse event 6 weeks after the procedure. The primary feasibility outcome measure was IIEF-15 (International Index of Erectile Function-15) score improvement ≥ 4 points in ≥ 50% of subjects on 6 weeks follow-up post intervention. RESULTS Fifty consecutive patients (mean age 61.8 ± 10.0 years) with severe erectile dysfunction due to venous leak underwent venous embolization. Procedural success was achieved in 49/50 (98%) of patients with no major adverse events on follow-up. The primary feasibility outcome measure at 6 weeks was reached by 34/50 (68%) of patients. CONCLUSION Venous leak embolization via deep dorsal penile vein access using a liquid embolic agent was safe for all and efficacious in the majority of patients with severe venogenic erectile dysfunction on 6 weeks follow-up

Sylvester-t' Hooft generators of sl(n) and sl(n|n), and relations between them

Among the simple finite dimensional Lie algebras, only sl(n) possesses two automorphisms of finite order which have no common nonzero eigenvector with eigenvalue one. It turns out that these automorphisms are inner and form a pair of generators that allow one to generate all of sl(n) under bracketing. It seems that Sylvester was the first to mention these generators, but he used them as generators of the associative algebra of all n times n matrices Mat(n). These generators appear in the description of elliptic solutions of the classical Yang-Baxter equation, orthogonal decompositions of Lie algebras, 't Hooft's work on confinement operators in QCD, and various other instances. Here I give an algorithm which both generates sl(n) and explicitly describes a set of defining relations. For simple (up to center) Lie superalgebras, analogs of Sylvester generators exist only for sl(n|n). The relations for this case are also computed.Comment: 14 pages, 6 figure

Structure Constants for New Infinite-Dimensional Lie Algebras of U(N+,N-) Tensor Operators and Applications

The structure constants for Moyal brackets of an infinite basis of functions on the algebraic manifolds M of pseudo-unitary groups U(N_+,N_-) are provided. They generalize the Virasoro and W_\infty algebras to higher dimensions. The connection with volume-preserving diffeomorphisms on M, higher generalized-spin and tensor operator algebras of U(N_+,N_-) is discussed. These centrally-extended, infinite-dimensional Lie-algebras provide also the arena for non-linear integrable field theories in higher dimensions, residual gauge symmetries of higher-extended objects in the light-cone gauge and C^*-algebras for tractable non-commutative versions of symmetric curved spaces.Comment: 8 pages, LaTeX, no figures; minor comments added; to appear in J. Phys A (Math. Gen.