83 research outputs found
Experimental study on discretely modulated continuous-variable quantum key distribution
We present a discretely modulated continuous-variable quantum key
distribution system in free space by using strong coherent states. The
amplitude noise in the laser source is suppressed to the shot-noise limit by
using a mode cleaner combined with a frequency shift technique. Also, it is
proven that the phase noise in the source has no impact on the final secret key
rate. In order to increase the encoding rate, we use broadband homodyne
detectors and the no-switching protocol. In a realistic model, we establish a
secret key rate of 46.8 kbits/s against collective attacks at an encoding rate
of 10 MHz for a 90% channel loss when the modulation variance is optimal.Comment: 7 pages,6 figure
Inverse saturable absorption mechanism and design optimization of mode-locked fiber lasers with a nonlinear amplifying loop mirror
From the point of view of the differential phase delay experienced by the two
counterpropagating optical fields, the self-starting of the mode-locked fiber
laser with a nonlinear amplifying loop mirror (NALM) is theoretically studied.
Although it is generally believed that NALM shows a saturable absorption effect
on both continuous wave (CW) light and pulses, we find a counter-intuitive fact
that cross-phase modulation (XPM) leads to opposite signs of differential
nonlinear phase shifts (NPSs) in these two cases, resulting in inverse
saturable absorption (ISA) during pulse formation process. The ISA is not
helpful for the self-starting of laser mode-locking and can be alleviated by
introducing a non-reciprocal phase shifter into the fiber loop. In addition, we
analyze the influences of gain-fiber position, splitting ratio, and optical
attenuator in the fiber loop, on the differential NPS and self-starting
process. These results are helpful for optimizing the design of NALM and
lowering the self-starting threshold of the high-repetition-rate mode-locked
fiber laser.Comment: 13 pages, 5 figure
Functional SNP in the 3’UTR of PON1 is Associated with the Risk of Calcific Aortic Valve Stenosis via MiR-616
Strong [O III] {\lambda}5007 Compact Galaxies Identified from SDSS DR16 and Their Scaling Relations
Green pea galaxies are a special class of star-forming compact galaxies with
strong [O III]{\lambda}5007 and considered as analogs of high-redshift
Ly{\alpha}-emitting galaxies and potential sources for cosmic reionization. In
this paper, we identify 76 strong [O III]{\lambda}5007 compact galaxies at z <
0.35 from DR1613 of the Sloan Digital Sky Survey. These galaxies present
relatively low stellar mass, high star formation rate, and low metallicity.
Both star-forming main sequence relation (SFMS) and mass-metallicity relation
(MZR) are investigated and compared with green pea and blueberry galaxies
collected from literature. It is found that our strong [O III] {\lambda}5007
compact galaxies share common properties with those compact galaxies with
extreme star formation and show distinct scaling relations in respect to those
of normal star-forming galaxies at the same redshift. The slope of SFMS is
higher, indicates that strong [O III]{\lambda}5007 compact galaxies might grow
faster in stellar mass. The lower MZR implies that they may be less chemically
evolved and hence on the early stage of star formation. A further environmental
investigation confirms that they inhabit relatively low-density regions. Future
largescale spectroscopic surveys will provide more details on their physical
origin and evolution.Comment: 12 pages, 8 figures, 1 table. Published in A
Syntropic spin alignment at the interface between ferromagnetic and superconducting nitrides
The magnetic correlations at the superconductor/ferromagnet (S/F) interfaces
play a crucial role in realizing dissipation-less spin-based logic and memory
technologies, such as triplet-supercurrent spin-valves and "{\pi}" Josephson
junctions. Here we report the coexistence of an induced large magnetic moment
and a crypto ferromagnetic state at high-quality nitride S/F interfaces. Using
polarized neutron reflectometry and d. c. SQUID measurements, we quantitatively
determined the magnetization profile of S/F bilayer and confirmed the induced
magnetic moment in the adjacent superconductor only exists below TC.
Interestingly, the direction of the induced moment in the superconductors was
unexpectedly parallel to that in the ferromagnet, which contrasts with earlier
findings in S/F heterostructures based on metals or oxides. The
first-principles calculations verify the observed unusual interfacial spin
texture is caused by the Heisenberg direct exchange coupling through d orbital
overlapping and severe charge transfer across the interfaces. Our work
establishes an incisive experimental probe for understanding the magnetic
proximity behavior at S/F interfaces and provides a prototype epitaxial
building block for superconducting spintronics.Comment: 21 pages, 5 figures, supplementary file with 14 figure
Involvement of Autophagy in Cardiac Remodeling in Transgenic Mice with Cardiac Specific Over-Expression of Human Programmed Cell Death 5
Programmed cell death 5 (PDCD5) is a cytosolic protein suppressing growth of multiple types of cancer cells through activating p53. We hypothesized that PDCD5 plays an essential role in cardiac remodeling and function. PDCD5 was significantly up-regulated in the hearts from mice subjected to angiotensin II treatment or transverse aortic constriction. Thus, we generated transgenic mice over-expressing human PDCD5 under the control of alpha myosin heavy chain promoter to examine the role of PDCD5 in cardiac remodeling. Transgenic founder died spontaneously displayed enlarged heart. The high PDCD5 over-expressing line (10-fold) showed reduced survival rate, increase in heart weight normalized to body weight. Real-Time RT-PCR analysis revealed fetal gene program was up-regulated. Echocardiography and histopathological examination showed characteristics of dilated cardiomyopathy and heart failure in transgenic mice. Western blot and immunohistochemistry analysis showed autophagy was dramatically increased in transgenic mice as compared to WT littermates control mice, while apoptosis remained unchanged. The enhanced autophagy in high over-expressing line was associated with significant increase in p53 activity and its downstream target damage-regulated autophagy modulator expression. The low over-expressing line (3.5-fold) appeared normal, but was more susceptible to angiotensin II-induced cardiac hypertrophy. This study is the first providing evidence that PDCD5 plays an important role in cardiac remodeling
Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples
Funder: NCI U24CA211006Abstract: The Cancer Genome Atlas (TCGA) and International Cancer Genome Consortium (ICGC) curated consensus somatic mutation calls using whole exome sequencing (WES) and whole genome sequencing (WGS), respectively. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2,658 cancers across 38 tumour types, we compare WES and WGS side-by-side from 746 TCGA samples, finding that ~80% of mutations overlap in covered exonic regions. We estimate that low variant allele fraction (VAF < 15%) and clonal heterogeneity contribute up to 68% of private WGS mutations and 71% of private WES mutations. We observe that ~30% of private WGS mutations trace to mutations identified by a single variant caller in WES consensus efforts. WGS captures both ~50% more variation in exonic regions and un-observed mutations in loci with variable GC-content. Together, our analysis highlights technological divergences between two reproducible somatic variant detection efforts
Shading-Interval Constraints for Normal Map Editing
Normal mapping is a compact representation to create visually rich shapes and shading effects. In this paper, we introduce a new paintbased approach to edit a normal map according to the intended shading, from realistic to non-realistic ones. For this purpose, we have formulated a normal-from-shading operation as a quadratic problem that makes use of intervals on shading. This approach ensures that the resulting normal map visually corresponds to the user-designed shading
Brexit and its consequences for Great Britain
National audienceIn this paper, we propose a novel method for normal texture editing based on shading maps. The presented method can be applied on both photo-realistic rendering and non-photorealistic rendering (NPR). By introducing shading interval constraints, the normal texture editing problem is characterized by a quadratic programming approach, which can be accelerated by GPU techniques. Experiments are presented, showing that for a 1024×1024 size normal texture, the computation costs only 3.6 milliseconds. The experimental results show that our proposed method is user-friendly and can be performed in real-time.了适于真实及非真实感图形绘制,提出一种基于绘制着色图的法向纹理编辑方法.通过引入着色区间约束概念,设计了一个法向纹理到着色图的非线性二次规划问题模型,并利用GPU技术实现了算法加速,方便了用户交互操作.实验结果表明,对于1024×1024大小的法向纹理,迭代计算的平均时间为3.6ms,能够达到实时的交互
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