R\uf6tliche L\ue4sion am Stamm

Anamnese 1 Ein 65-j\ue4hriger Patient, der im Gesichtsbereich bereits chronische Lichtsch\ue4den aufwies, wurde im Rahmen des Nierentransplantationsscreenings wegen einer neu aufgetretenen r\uf6tlichen L\ue4sion in unserer Ambulanz vorstellig. Der Patient selbst bemerkte die L\ue4sion nicht. Anamnese 2 Eine 59-j\ue4hrige Patientin kam wegen multipler N\ue4vi zur allj\ue4hrlichen Routinekontrolle. Die neu aufgetretene r\uf6tliche Papel am R\ufccken rechts war ihr nicht aufgefallen

Desmoplastic Trichoepithelioma and Melanocytic Nevus: Dermoscopic and Reflectance Confocal Microscopy Presentation of a Rare Collision Tumor

A 27-year-old woman presented with a 2-year history of an asymptomatic papule located on her right cheek. The physical examination revealed a firm, well-defined with a raised annular border, skin-colored papule, 5 mm in maximum diameter

Lacunarity Analysis: A Promising Method for the Automated Assessment of Melanocytic Naevi and Melanoma

The early diagnosis of melanoma is critical to achieving reduced mortality and increased survival. Although clinical examination is currently the method of choice for melanocytic lesion assessment, there is a growing interest among clinicians regarding the potential diagnostic utility of computerised image analysis. Recognising that there exist significant shortcomings in currently available algorithms, we are motivated to investigate the utility of lacunarity, a simple statistical measure previously used in geology and other fields for the analysis of fractal and multi-scaled images, in the automated assessment of melanocytic naevi and melanoma. Digitised dermoscopic images of 111 benign melanocytic naevi, 99 dysplastic naevi and 102 melanomas were obtained over the period 2003 to 2008, and subject to lacunarity analysis. We found the lacunarity algorithm could accurately distinguish melanoma from benign melanocytic naevi or non-melanoma without introducing many of the limitations associated with other previously reported diagnostic algorithms. Lacunarity analysis suggests an ordering of irregularity in melanocytic lesions, and we suggest the clinical application of this ordering may have utility in the naked-eye dermoscopic diagnosis of early melanoma

inTrack: High Precision Tracking of Mobile Sensor Nodes

Radio-interferometric ranging is a novel technique that allows for fine-grained node localization in networks of inexpensive COTS nodes. In this paper, we show that the approach can also be applied to precision tracking of mobile sensor nodes. We introduce inTrack, a cooperative tracking system based on radio-interferometry that features high accuracy, long range and low-power operation. The system utilizes a set of nodes placed at known locations to track a mobile sensor. We analyze how target speed and measurement errors affect the accuracy of the computed locations. To demonstrate the feasibility of our approach, we describe our prototype implementation using Berkeley motes. We evaluate the system using data from both simulations and field tests

Dermoscopy in the era of dermato-oncology: from bed to bench side and retour

Today dermoscopy is standard-of-care in the diagnosis and management of patients with benign and malignant skin tumors because it increases the diagnostic accuracy of skin lesions compared to the naked-eye examination up to 25%. Despite its role in the routine dermato-oncology, it increasingly gained interest as a bridge connecting clinical with basic molecular research in dermato-oncology. Here, we correlate dermoscopy patterns of nevi and melanomas with high and low susceptibility genes and somatic mutations, provide an overview on the clinical and dermoscopic patterns of cutaneous melanoma subtypes, and highlight the role of dermoscopy in the diagnosis of skin eruptions during systemic treatments of advanced melanoma including targeted therapies and immunotherapies

Effects of a Chemical Sunscreen on UV-Induced Changes of Different Histological Features in Melanocytic Nevi

Several studies have investigated the effect of UV radiation on melanocytic nevi by using different approaches and different sources and types of irradiation.1 We read with interest the work of Carrera et al,2 and we would like to describe our experience also

GNSS jamming resilience for close to shore navigation in the Northern Sea

avigational error accounts for half of the accidents and serious incidents in close to shore maritime transport in Norway predominantly due to the rapidly changing weather conditions and the dangerous nature of the narrow inshore waters found along the Norwegian coast. This creates a dependence on Differential Global Positioning System (DGPS) use and any disruption to this service can lead to an increased accident rate. The aim of this paper is to research the jamming vulnerability of existing maritime receivers and to understand if an upgrade to a multi-constellation or multi-frequency receiver would improve system resilience. The novelty of this work is a comparison of jamming resilience between different combinations of multiple constellations (GPS and Globalnaya Navigatsionnaya Sputnikovaya Sistema (GLONASS)) and multi-frequency Global Navigation Satellite System (GNSS) signals. This paper presents results from GNSS jamming trials conducted in the northern part of Norway, confirming previous research and indicating that typical maritime GPS receivers are easy to jam and may produce erroneous positional information. Results demonstrate that the single frequency multi-constellation receivers offer better jamming resilience than multi-frequency (L1 + L2) GPS receivers. Further, the GLONASS constellation demonstrated a better resilience than GPS. Results demonstrate a known correlation between GPS L1 and L2 frequencies, as well as a probable over-dependence on GPS for signal acquisition, meaning that no signal can be received without GPS L1 present. With these limitations in mind, the authors suggest that the most economic update to the single frequency GPS receivers, currently used for maritime applications, should be multi-constellation GPS + GLONASS receivers. This solution is cheaper and it also offer better jamming resistance for close to shore navigation than dual frequency receivers

The use of mobile phones for skin tumor screening

A lot of importance is attributed to mobile telemedicine these days, a topic that encompasses a wide and ever growing range of applications. Small, handheld devices such as camera mobile phones have come into every day use providing technically sophisticated tasks on a user-friendly level and can therefore be easily used in various fields of telemedicine. Dermatology is a perfect candidate for the use of telemedicine tools in general, as well as mobile devices in particular. The unique aspect of mobile teledermatology is that this system represents a filtering, or triage system, allowing a sensitive approach for the management of patients with emergent skin diseases. In order to investigate the feasibility of teleconsultation using a new generation of cellular phones, a clinical study to evaluate the accuracy of online diagnosis of skin tumours was conducted. Teledermoscopy represents a recent development of teledermatology that might add up additional information in the diagnosis of pigmented skin lesions. Teledermatology, mobile as well as stationary, can advance the reliability of diagnosis by expert consultations without expensive and time-consuming relocations. Consequently, the quality of patient's care can be raised and the costs of the health care system can be reduced

concordance and time estimation of store and forward mobile teledermatology compared to classical face to face consultation

Smartphones have overcome the limitations of image quality seen in older devices and opened a new field of telemedicine called "mobile teledermatology". Technological advances and the need to reduce health service costs will strongly promote the development of telemedicine. For this reason, we evaluated the concordance be tween store-and-forward mobile teledermatology and the classical face-to-face dermatological visit. We also measured the time taken to submit a teleconsultation using a smartphone. Before conventional face-to-face visit, a final-year resident of the 3-year course for general practitioners collected medical history, took digital images of skin diseases with a smartphone and, measuring the time required to complete this operation, transmitted them to an expert teledermatologist. In 391 patients we obtained a concordance between face-to-face and store-and-forward diagnosis of 91.05% (Cohen κ coefficient = 0.906). On average only few minutes needs to be added to a no

GPS Remote Sensing Measurements Using Aerosonde UAV

In February 2004, a NASA-Langley GPS Remote Sensor (GPSRS) unit was flown on an Aerosonde unmanned aerial vehicle (UAV) from the Wallops Flight Facility (WFF) in Virginia. Using direct and surface-reflected 1.575 GHz coarse acquisition (C/A) coded GPS signals, remote sensing measurements were obtained over land and portions of open water. The strength of the surface-reflected GPS signal is proportional to the amount of moisture in the surface, and is also influenced by surface roughness. Amplitude and other characteristics of the reflected signal allow an estimate of wind speed over open water. In this paper we provide a synopsis of the instrument accommodation requirements, installation procedures, and preliminary results from what is likely the first-ever flight of a GPS remote sensing instrument on a UAV. The correct operation of the GPSRS unit on this flight indicates that Aerosonde-like UAV's can serve as platforms for future GPS remote sensing science missions