6,009 research outputs found
An experimental study of the buckling of complete spherical shells
Buckling of complete spherical shells to examine Tsien energy hypothesi
Opening the Pandora's box of quantum spinor fields
Lounesto's classification of spinors is a comprehensive and exhaustive
algorithm that, based on the bilinears covariants, discloses the possibility of
a large variety of spinors, comprising regular and singular spinors and their
unexpected applications in physics and including the cases of Dirac, Weyl, and
Majorana as very particular spinor fields. In this paper we pose the problem of
an analogous classification in the framework of second quantization. We first
discuss in general the nature of the problem. Then we start the analysis of two
basic bilinear covariants, the scalar and pseudoscalar, in the second quantized
setup, with expressions applicable to the quantum field theory extended to all
types of spinors. One can see that an ampler set of possibilities opens up with
respect to the classical case. A quantum reconstruction algorithm is also
proposed. The Feynman propagator is extended for spinors in all classes.Comment: 18 page
Effective action for a quantum scalar field in warped spaces
We investigate the one-loop corrections at zero, as well as finite
temperature, of a scalar field taking place in a braneworld motived warped
background. After to reach a well defined problem, we calculate the effective
action with the corresponding quantum corrections to each case.Comment: 10 pages, to appear in The European Physical Journal
Straight spinning cosmic strings in Brans-Dicke gravity
It is presented an exact solution of straight spinning cosmic strings in
Brans-Dicke theory of gravitation. The possibility of the existence of closed
timelike curves around these cosmic strings is analyzed. Furthermore, the
stability about the formation of the topological defect discussed here is
checked. It is shown the existence of a suitable choice for the integration
constants in which closed timelike curves are not allowed. We also verify if it
is possible that the obtained spacetime can be the source that describes the
observed rotational curves in some galaxies.Comment: 13 pages, 1 figur
Constraining Elko Dark Matter at the LHC with Monophoton Events
A mass dimension one fermion, also known as Elko, constitutes a dark matter
candidate which might interact with photons at the tree level in a specific
fashion. In this work, we investigate the constraints imposed by unitarity and
LHC data on this type of interactions using the search for new physics in
monophoton events. We found that Elkos which can explain the dark matter relic
abundance mainly through electromagnetic interactions are excluded at the
95\%CL by the 8 TeV LHC data for masses up to 1 TeV.Comment: 6 pages, 4 figure
A nearly cylindrically symmetric source in the Brans-Dicke gravity as the generator of the rotational curves of the galaxies
Observation shows that the velocities of stars grow by approximately 2 to 3
orders of magnitude when the distances from the centers of the galaxies are in
the range of kpc to kpc, before they begin to tend to a constant
value. Up to know, the reason for this behavior is still a matter for debate.
In this work, we propose a model which adequately describes this unusual
behavior using a (nearly) cylindrical symmetrical solution in the framework of
a scalar-tensor-like (the Brans-Dicke model) theory of gravity.Comment: 24 pages, 4 figures, accepted for publication in Eur. Phys. J.
Synthetic control of a fitness tradeoff in yeast nitrogen metabolism
Background:
Microbial communities are involved in many processes relevant to industrial and medical biotechnology, such as the formation of biofilms, lignocellulosic degradation, and hydrogen production. The manipulation of synthetic and natural microbial communities and their underlying ecological parameters, such as fitness, evolvability, and variation, is an increasingly important area of research for synthetic biology.
Results:
Here, we explored how synthetic control of an endogenous circuit can be used to regulate a tradeoff between fitness in resource abundant and resource limited environments in a population of Saccharomyces cerevisiae. We found that noise in the expression of a key enzyme in ammonia assimilation, Gdh1p, mediated a tradeoff between growth in low nitrogen environments and stress resistance in high ammonia environments. We implemented synthetic control of an endogenous Gdh1p regulatory network to construct an engineered strain in which the fitness of the population was tunable in response to an exogenously-added small molecule across a range of ammonia environments.
Conclusion:
The ability to tune fitness and biological tradeoffs will be important components of future efforts to engineer microbial communities
Hsc66 substrate specificity is directed toward a discrete region of the iron-sulfur cluster template protein IscU
Hsc66 and Hsc20 comprise a specialized chaperone system important for the assembly of iron-sulfur clusters in Escherchia coli. Only a single substrate, the Fe/S template protein IscU, has been identified for the Hsc66/Hsc20 system, but the mechanism by which Hsc66 selectively binds IscU is unknown. We have investigated Hsc66 substrate specificity using phage display and a peptide array of IscU. Screening of a heptameric peptide phage display library revealed that Hsc66 prefers peptides with a centrally located Pro-Pro motif. Using a cellulose-bound peptide array of IscU we determined that Hsc66 interacts specifically with a region (residues 99-103, LPPVK) that is invariant among all IscU family members. A synthetic peptide (ELPPVKIHC) corresponding to IscU residues 98-106 behaves in a similar manner to native IscU, stimulating the ATPase activity of Hsc66 with similar affinity as IscU, preventing Hsc66 suppression of bovine rhodanese aggregation, and interacting with the peptide-binding domain of Hsc66. Unlike native IscU, however, the synthetic peptide is not bound by Hsc20 and does not synergistically stimulate Hsc66 ATPase activity with Hsc20. Our results indicate that Hsc66 and Hsc20 recognize distinct regions of IscU and further suggest that Hsc66 will not bind LPPVK motifs with high affinity in vivo unless they are in the context of native IscU and can be directed to Hsc66 by Hsc20
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