62 research outputs found
Personal data protection with focus on processing and protection in civil aviation
Personal Data Protection with Focus on Processing and Protection in Civil Aviation This diploma thesis focuses on the matter of EU legal regulation of personal data protection and reflects it in the field of civil aviation with focus on commercial air transport, as commercial air transport is at this moment the area of civil aviation where most of the personal data processing and operations with them are made. The goals of this diploma thesis are mainly to describe respective personal data processing in civil aviation and finding out whether GDPR represents an insurmountable legal obstacle for air carriers and civil aviation to operate or whether it is just another complicated act of legislation that air carriers and other entities in civil aviation must reflect. The first chapter of the thesis briefly introduces the history of personal data protection while presenting some of its past and current sources of legislation. Moreover, the first chapter introduces certain legal institutes of current EU personal data protection legislation and draws attention to the continuity and discontinuity of GDPR with the previous one. The second chapter of the thesis provides a short introduction to the topic of civil aviation legislation and describes the relationship between this legislation and GDPR. The...Ochrana osobních údajů se zaměřením na jejich zpracování a ochranu v civilním letectví Tato diplomová práce se zaměřuje na problematiku právní úpravy ochrany osobních údajů EU, přičemž se pokouší tuto problematiku reflektovat v rovině civilního letectví s důrazem na obchodní leteckou dopravu. Právě v rámci obchodní letecké dopravy totiž dochází v civilním letectví ke zpracování největšího množství osobních údajů a k nejvyššímu počtu operací prováděných s osobními údaji. Cílem diplomové práce je především popsat jednotlivá zpracování osobních údajů v civilním letectví a zhodnotit, zda GDPR představuje pro letecké dopravce a civilní letectví nepřekonatelnou právní překážku pro provozování dané činnosti, nebo se jedná pouze o další komplikovaný právní předpis, ke kterému musí přihlížet letečtí dopravci a další subjekty pohybující se v civilním letectví. První kapitola diplomové práce se stručně věnuje historii ochrany osobních údajů, resp. uvádí některé její historické a současné prameny právní úpravy. Následně první kapitola představuje některé právní instituty ochrany osobních údajů a upozorňuje na kontinuitu a diskontinuitu GDPR s předchozí právní úpravou. Druhá kapitola diplomové práce stručně seznamuje s problematikou právní úpravy civilního letectví a popisuje vztahy mezi touto právní úpravou a...Department of European LawKatedra evropského právaPrávnická fakultaFaculty of La
Personal Data Protection with Focus on Processing and Protection in Civil Aviation
Ochrana osobních údajů se zaměřením na jejich zpracování a ochranu v civilním letectví Tato diplomová práce se zaměřuje na problematiku právní úpravy ochrany osobních údajů EU, přičemž se pokouší tuto problematiku reflektovat v rovině civilního letectví s důrazem na obchodní leteckou dopravu. Právě v rámci obchodní letecké dopravy totiž dochází v civilním letectví ke zpracování největšího množství osobních údajů a k nejvyššímu počtu operací prováděných s osobními údaji. Cílem diplomové práce je především popsat jednotlivá zpracování osobních údajů v civilním letectví a zhodnotit, zda GDPR představuje pro letecké dopravce a civilní letectví nepřekonatelnou právní překážku pro provozování dané činnosti, nebo se jedná pouze o další komplikovaný právní předpis, ke kterému musí přihlížet letečtí dopravci a další subjekty pohybující se v civilním letectví. První kapitola diplomové práce se stručně věnuje historii ochrany osobních údajů, resp. uvádí některé její historické a současné prameny právní úpravy. Následně první kapitola představuje některé právní instituty ochrany osobních údajů a upozorňuje na kontinuitu a diskontinuitu GDPR s předchozí právní úpravou. Druhá kapitola diplomové práce stručně seznamuje s problematikou právní úpravy civilního letectví a popisuje vztahy mezi touto právní úpravou a...Personal Data Protection with Focus on Processing and Protection in Civil Aviation This diploma thesis focuses on the matter of EU legal regulation of personal data protection and reflects it in the field of civil aviation with focus on commercial air transport, as commercial air transport is at this moment the area of civil aviation where most of the personal data processing and operations with them are made. The goals of this diploma thesis are mainly to describe respective personal data processing in civil aviation and finding out whether GDPR represents an insurmountable legal obstacle for air carriers and civil aviation to operate or whether it is just another complicated act of legislation that air carriers and other entities in civil aviation must reflect. The first chapter of the thesis briefly introduces the history of personal data protection while presenting some of its past and current sources of legislation. Moreover, the first chapter introduces certain legal institutes of current EU personal data protection legislation and draws attention to the continuity and discontinuity of GDPR with the previous one. The second chapter of the thesis provides a short introduction to the topic of civil aviation legislation and describes the relationship between this legislation and GDPR. The...Department of European LawKatedra evropského právaFaculty of LawPrávnická fakult
Synthesis of β-d-galactopyranoside-Presenting Glycoclusters, Investigation of Their Interactions with Pseudomonas aeruginosa Lectin A (PA-IL) and Evaluation of Their Anti-Adhesion Potential
Pseudomonas aeruginosa is an opportunistic human pathogen associated with cystic fibrosis.
This bacterium produces, among other virulence factors, a soluble d-galactose-specific lectin PA-IL
(LecA). PA-IL plays an important role in the adhesion to the host cells and is also cytotoxic. Therefore,
this protein is an interesting therapeutic target, suitable for inhibition by carbohydrate-based
compounds. In the current study, ß-d-galactopyranoside-containing tri- and tetravalent glycoclusters
were synthesized. Methyl gallate and pentaerythritol equipped with propargyl groups were chosen
as multivalent scffolds and the galactoclusters were built from the above-mentioned cores by
coupling ethylene or tetraethylene glycol-bridges and peracetylated propargyl ß-d-galactosides
using 1,3-dipolar azide-alkyne cycloaddition. The interaction between galactoside derivatives and
PA-IL was investigated by several biophysical methods, including hemagglutination inhibition assay,
isothermal titration calorimetry, analytical ultracentrifugation, and surface plasmon resonance. Their
ability to inhibit the adhesion of P. aeruginosa to bronchial cells was determined by ex vivo assay.
The newly synthesized multivalent galactoclusters proved to be significantly better ligands than
simple d-galactose for lectin PA-IL and as a result, two representatives of the dendrimers were able
to decrease adhesion of P. aeruginosa to bronchial cells to approximately 32% and 42%, respectively.
The results may provide an opportunity to develop anti-adhesion therapy for the treatment of
P. aeruginosa infection
Mannich-type modifications of (−)-cannabidiol and (−)-cannabigerol leading to new, bioactive derivatives
(−)-Cannabidiol (CBD) and (−)-cannabigerol (CBG) are two major non-psychotropic phytocannabinoids that have many beneficial biological properties. However, due to their low water solubility and prominent first-pass metabolism, their oral bioavailability is moderate, which is unfavorable for medicinal use. Therefore, there is a great need for appropriate chemical modifications to improve their physicochemical and biological properties. In this study, Mannich-type reaction was used for the synthetic modification of CBD and CBG for the first time, and thus fifteen new cannabinoid derivatives containing one or two tertiary amino groups were prepared. Thereafter the antiviral, antiproliferative and antibacterial properties of the derivatives and their effects on certain skin cells were investigated. Some modified CBD derivatives showed remarkable antiviral activity against SARS-CoV-2 without cytotoxic effect, while synthetic modifications on CBG resulted in a significant increase in antiproliferative activity in some cases compared to the parent compound
Effect of within-species plant genotype mixing on habitat preference of a polyphagous insect predator
The effects of within-species plant genotype mixing on the habitat preference of a polyphagous ladybird were studied. Plant species diversity is often claimed to positively affect habitat preferences of insect predators, but the effects of within-species genotype diversity have not been extensively studied. In a field experiment with different barley (Hordeum vulgare) genotypes in mixed and pure stands, adult seven-spot ladybird Coccinella septempunctata, a polyphagous predator, preferred a specific combination of genotypes over the single genotypes alone before aphids had arrived in the crop, and again when aphids were emigrating. In laboratory experiments on adult ladybird orientation to odour from barley, ladybirds were attracted/arrested by the mixed odour of the same barley genotype mixture that was preferred in the field. Exposure of one barley genotype to volatiles from the other also caused the odour of the exposed plants to become more attractive to ladybirds. The results support the hypothesis that plant volatiles may attract or arrest foraging adult ladybirds, contributing to the selection of favourable habitats, and they show that within-species plant genotype mixing can shape interactions within multitrophic communities
Personal Data Protection with Focus on Processing and Protection in Civil Aviation
Personal Data Protection with Focus on Processing and Protection in Civil Aviation This diploma thesis focuses on the matter of EU legal regulation of personal data protection and reflects it in the field of civil aviation with focus on commercial air transport, as commercial air transport is at this moment the area of civil aviation where most of the personal data processing and operations with them are made. The goals of this diploma thesis are mainly to describe respective personal data processing in civil aviation and finding out whether GDPR represents an insurmountable legal obstacle for air carriers and civil aviation to operate or whether it is just another complicated act of legislation that air carriers and other entities in civil aviation must reflect. The first chapter of the thesis briefly introduces the history of personal data protection while presenting some of its past and current sources of legislation. Moreover, the first chapter introduces certain legal institutes of current EU personal data protection legislation and draws attention to the continuity and discontinuity of GDPR with the previous one. The second chapter of the thesis provides a short introduction to the topic of civil aviation legislation and describes the relationship between this legislation and GDPR. The..
Úkoly odboru koordinace výroby při tvorbě pořadů v prvním studiovém bloku televizního střediska na Kavčích horách
Development and validation of methods for GMO detection
The present work is focused on the issue of genetically modified organisms (GMOs) detection in the plants and derived products. Existing legislation in the European Union regulates monitoring of GMO and lays down rules for their labeling and traceability. The aim was to contribute to solving certain issues of critical points in GMO detection. The first point was DNA extraction. The problem was adressed to the example of DNA extraction from the fruit of papaya and candied papaya. For both food products the suitability of the selected extraction methods was verified and confirmed by amplification of a specific DNA sequence by PCR. The second critical point was related to PCR inhibitors. We observed the effect of real-time PCR inhibition due to the influence of the residual EDTA and the residual amount of heavy metal ions, which were present in laboratory plastic. In both examples, the inhibition affects the PCR efficiency. Another critical point in the GMO detection is use of screening elements. That work was focused on false positive results. Development of new methods for GMO detection was another goal of this work. We have developed the method for garden pea taxon-specific gene quantification by real-time PCR. The method was tested on 13 cultivars of garden pea and several related plants of..
Personal data protection with focus on processing and protection in civil aviation
Personal Data Protection with Focus on Processing and Protection in Civil Aviation This diploma thesis focuses on the matter of EU legal regulation of personal data protection and reflects it in the field of civil aviation with focus on commercial air transport, as commercial air transport is at this moment the area of civil aviation where most of the personal data processing and operations with them are made. The goals of this diploma thesis are mainly to describe respective personal data processing in civil aviation and finding out whether GDPR represents an insurmountable legal obstacle for air carriers and civil aviation to operate or whether it is just another complicated act of legislation that air carriers and other entities in civil aviation must reflect. The first chapter of the thesis briefly introduces the history of personal data protection while presenting some of its past and current sources of legislation. Moreover, the first chapter introduces certain legal institutes of current EU personal data protection legislation and draws attention to the continuity and discontinuity of GDPR with the previous one. The second chapter of the thesis provides a short introduction to the topic of civil aviation legislation and describes the relationship between this legislation and GDPR. The..
Kundenbindung und Wechselverhalten in der privaten Krankenversicherung
Hodek J-M. Kundenbindung und Wechselverhalten in der privaten Krankenversicherung. Göttingen: Cuvillier; 2010
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