59 research outputs found
The changing global distribution and prevalence of canine transmissible venereal tumour.
BACKGROUND: The canine transmissible venereal tumour (CTVT) is a contagious cancer that is naturally transmitted between dogs by the allogeneic transfer of living cancer cells during coitus. CTVT first arose several thousand years ago and has been reported in dog populations worldwide; however, its precise distribution patterns and prevalence remain unclear. RESULTS: We analysed historical literature and obtained CTVT prevalence information from 645 veterinarians and animal health workers in 109 countries in order to estimate CTVT's former and current global distribution and prevalence. This analysis confirmed that CTVT is endemic in at least 90 countries worldwide across all inhabited continents. CTVT is estimated to be present at a prevalence of one percent or more in dogs in at least 13 countries in South and Central America as well as in at least 11 countries in Africa and 8 countries in Asia. In the United States and Australia, CTVT was reported to be endemic only in remote indigenous communities. Comparison of current and historical reports of CTVT indicated that its prevalence has declined in Northern Europe, possibly due to changes in dog control laws during the nineteenth and twentieth centuries. Analysis of factors influencing CTVT prevalence showed that presence of free-roaming dogs was associated with increased CTVT prevalence, while dog spaying and neutering were associated with reduced CTVT prevalence. Our analysis indicated no gender bias for CTVT and we found no evidence that animals with CTVT frequently harbour concurrent infectious diseases. Vincristine was widely reported to be the most effective therapy for CTVT. CONCLUSIONS: Our results provide a survey of the current global distribution of CTVT, confirming that CTVT is endemic in at least 90 countries worldwide. Additionally, our analysis highlights factors that continue to modify CTVT's prevalence around the world and implicates free-roaming dogs as a reservoir for the disease. Our analysis also documents the disappearance of the disease from the United Kingdom during the twentieth century, which appears to have been an unintentional result of the introduction of dog control policies.This is the author's accepted manuscript. The final version of this article has been published by BioMed Central: http://www.biomedcentral.com/1746-6148/10/168
Understanding the adsorption process in ZIF-8 using high pressure crystallography and computational modelling
Understanding host–guest interactions and structural changes within porous materials is crucial for enhancing gas storage properties. Here, the authors combine cryogenic loading of gases with high pressure crystallography and computational techniques to obtain atomistic detail of adsorption-induced structural and energetic changes in ZIF-8
High Post-Capture Survival for Sharks, Rays and Chimaeras Discarded in the Main Shark Fishery of Australia?
Most sharks, rays and chimaeras (chondrichthyans) taken in commercial fisheries are discarded (i.e. returned to the ocean either dead or alive). Quantifying the post-capture survival (PCS) of discarded species is therefore essential for the improved management and conservation of this group. For all chondrichthyans taken in the main shark fishery of Australia, we quantified the immediate PCS of individuals reaching the deck of commercial shark gillnet fishing vessels and applied a risk-based method to semi-quantitatively determine delayed and total PCS. Estimates of immediate, delayed and total PCS were consistent, being very high for the most commonly discarded species (Port Jackson shark, Australian swellshark, and spikey dogfish) and low for the most important commercial species (gummy and school sharks). Increasing gillnet soak time or water temperature significantly decreased PCS. Chondrichthyans with bottom-dwelling habits had the highest PCS whereas those with pelagic habits had the lowest PCS. The risk-based approach can be easily implemented as a standard practice of on-board observing programs, providing a convenient first-step assessment of the PCS of all species taken in commercial fisheries
Accommodating Dynamic Oceanographic Processes and Pelagic Biodiversity in Marine Conservation Planning
Pelagic ecosystems support a significant and vital component of the ocean's productivity and biodiversity. They are also heavily exploited and, as a result, are the focus of numerous spatial planning initiatives. Over the past decade, there has been increasing enthusiasm for protected areas as a tool for pelagic conservation, however, few have been implemented. Here we demonstrate an approach to plan protected areas that address the physical and biological dynamics typical of the pelagic realm. Specifically, we provide an example of an approach to planning protected areas that integrates pelagic and benthic conservation in the southern Benguela and Agulhas Bank ecosystems off South Africa. Our aim was to represent species of importance to fisheries and species of conservation concern within protected areas. In addition to representation, we ensured that protected areas were designed to consider pelagic dynamics, characterized from time-series data on key oceanographic processes, together with data on the abundance of small pelagic fishes. We found that, to have the highest likelihood of reaching conservation targets, protected area selection should be based on time-specific data rather than data averaged across time. More generally, we argue that innovative methods are needed to conserve ephemeral and dynamic pelagic biodiversity
Tracking reveals limited interactions between Campbell Albatross and fisheries during the breeding season
International audienceFisheries-related mortality has been influential in driving global declines in seabird populations. Understanding the overlap between seabird distribution and fisheries is one important element in assessing bycatch risk, and may be achieved by tracking the movements of individual birds and fishing vessels. Here, we assess the spatiotemporal overlap between the vulnerable Campbell Albatross Thalassarche impavida and large (>28 m) commercial fishing boats in New Zealand’s Exclusive Economic Zone (EEZ). We used a novel analytical approach, bivariate Gaussian bridge movement modelling, to compute spatiotemporal utilization distributions of bird-borne global positioning system (GPS) loggers and data from the Vessel Monitoring System. We tracked birds for 28,815 h during incubation and chick brooding, with half of this time spent within New Zealand’s EEZ, utilizing 6.7% of the available area. However, there was no evidence that albatrosses and fishing vessels were in the same location simultaneously. We accounted for the broader ecological footprint of fishing vessels by calculating the distance between GPS-fix locations for albatrosses and fishing vessels, revealing that albatrosses were within 30 km of fishing vessels in 8.4% of foraging trips. This highlights differences in estimated fine-scale spatiotemporal overlaps which may be due to the distance between albatrosses and vessels or the methods used. Overall, the low levels of spatial overlap could be a result of Campbell Albatross’ preference for foraging in areas without fishing activity or competitive exclusion by other species. Our results reinforce the importance of multi-scale, temporally explicit, and multi-national approaches to risk assessment, as Campbell Albatrosses spend approximately half of their time foraging outside New Zealand’s EEZ
Corporate boards and the performance of Asian firms: A meta-analysis
The prevalence of ownership concentration in Asian firms presents a challenge to the influential agency theory-based understanding of the role of corporate boards. In this paper we develop and test hypotheses about board attributes and firm performance that reflect Asian institutional conditions. We present the first meta-analysis of the relationship between board attributes and performance of Asian firms using a varied set of meta-analytical techniques on a database of 86 studies covering nine Asian countries. First, we find that board structure and composition preferences are influenced by the identity of the concentrated owner. Second, consistent with US data, we find very limited evidence of a direct relationship between board attributes and firm financial performance in the Asian context. Third, we find that the relationship between board structure and composition and firm performance is mediated by the revealed strategic preferences of Asian firms specifically by the level of R&D investment
Delivering better outcomes through customer-led project management: the case of the major project BT 21st Century Network in the UK
Traditional approaches of major project management take the strategy of selecting a supplier-led prime/systems integrator. Although this strategy pushes a significant amount of risk to the supplier, project performance may suffer due to lower engagement of the customer in the anticipation of potential issues involving a major project. Thus, this research investigates the implications of the customer, as opposed to a selected external supplier, assuming the role of systems/prime integrator, as a Problem Structuring Method (PSM) to better deal with the soft side and uncertainties of the project. A case study approach is conducted on the major project BT 21st Century Network (BT21CN) to demonstrate that customer-led systems integration projects may provide more balance in the relationship and distribution of risks between supplier and customer, having a positive impact on project performance, accelerating the development of BT’s organisational capabilities, and producing better project outcomes in the long term
Zoofolkloristika: Prvi uvidi na putu prema novoj disciplini
The author notes that new, more complex researches of connections between animals, nature and connections to humans are needed in Slovenian and European folklore, literature and cultural studies, due to new ecological and ethical findings in the wider social and cultural environment and a changing order of the world, which has moved the focus from anthropocentrism into ecocentrism. The discussion builds upon various theoretical discourses, new concepts and multidisciplinary knowledge, to create the foundations, guidelines and directions for a new academic discipline of zoofolkloristics. Furthermore, new theoretical and analytical discourses should enable zoofolkloristics to provide an insight into changes in human attitudes to animals, in both folklore and within traditional and contemporary ritual practices, or their redefinition, and at the same time exert influence upon legal safety of non-human subjectivities.Autorica polazi od tvrdnje da su potrebna nova, kompleksnija istraživanja veza između životinja, prirode i poveznica s ljudima u slovenskoj i europskoj folkloristici, znanosti o književnosti i kulturnim studijima, zbog novih ekoloških i etičkih uvida u širu društveno-kulturnu okolinu i promjene u svijetu, koje su dovele do promjene od antropocentrizma k ekocentrizmu. U radu se na temelju različitih teorijskih diskursa, novih pojmova i multidisciplinarnog znanja stvaraju temelji, smjernice i pravci istraživanja u novoj znanstvenoj disciplini zoofolkloristike. Autorica tvrdi da bi etnologija, folkloristika i znanost o književnosti mogle imati ključnu ulogu u razvoju ekološke svijesti, znanstvenih terenskih istraživanja i kulturne ekologije te tako omogućiti prelazak iz ekologije u eshatologiju. Rad započinje opisom percepcije životinja i odnosa ljudi i životinja, gdje autorica govori o temeljnim pojmovima koji utječu na uvođenje ove nove znanstvene discipline, kao što su: životinja kao ispitanik, individualni pristup životinji, sinantropski i antropofilni pogled na čovjeka i životinju te antropomorfizam. Zatim se govori o povijesnim i suvremenim filozofsko-antropološkim diskursima o ljudskom pogledu na životinju te o teoriji specizma. Autorica razmatra predmet nove discipline te kaže da je u centru istraživanja životinja u folkloru u najširem mogućem smislu, u svim sferama narodne kulture, što se proučava iz novih gledišta, nove percepcije i recepcije; u pjesmama, pričama, bajkama, basnama, predajama, poslovicama, izrekama, zagonetkama, šalama, narodnom jeziku, kulturnim praksama, narodnom teatru, mitologiji, narodnoj medicini pa čak i u narodnoj glazbi. Nadalje, autorica daje pregled kulturnih istraživanja životinja u Europi i Sloveniji, te pokazuje da su rasprave o životinjama uglavnom objavljivane u 21. stoljeću, što bi moglo označavati da je riječ o prelasku u novu paradigmu ili čak i novu ontologiju. Autorica se bavi metodološkim i teorijskim pitanjima i pravcima u zoofolklorističkim istraživanjima koje klasificira prema kritičkom diskursu. Rad završava pregledom ciljeva zoofolkloristike, za koju tvrdi da ne bi smjela postati znanstvena disciplina koja nema aktivan utjecaj na društvenopolitički prostor u kojem koegzistiraju ljudski i ne-ljudski subjektiviteti
Breast cancer cells can switch between estrogen receptor α and ErbB signaling and combined treatment against both signaling pathways postpones development of resistance
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