10 research outputs found
Extensible Architectures: The Strategic Value of Service Oriented Architecture in Banking
Information and communication technology (ICT) has helped to drive increasingly intense global competition. In turn, this intensity increases the need for flexibility and rapid changeability in ICT to support strategies that depend on organizational agility. We report a comparative, cross-cultural case study of the implementation of Service Oriented Architectures (SOA) at a Scandinavian bank and a Swiss bank. The strategic rewards in the adoption of SOA appear to go beyond marketplace issues of ICT capability acquisition, and unexpectedly arise in the creation of an extensible organizational ICT architecture. The extensibility of the ICT architecture that results from the adoption of SOA provides potential for greater organizational agility (and thereby competitiveness)
Effect of remote ischaemic conditioning on clinical outcomes in patients with acute myocardial infarction (CONDI-2/ERIC-PPCI): a single-blind randomised controlled trial.
BACKGROUND: Remote ischaemic conditioning with transient ischaemia and reperfusion applied to the arm has been shown to reduce myocardial infarct size in patients with ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PPCI). We investigated whether remote ischaemic conditioning could reduce the incidence of cardiac death and hospitalisation for heart failure at 12 months. METHODS: We did an international investigator-initiated, prospective, single-blind, randomised controlled trial (CONDI-2/ERIC-PPCI) at 33 centres across the UK, Denmark, Spain, and Serbia. Patients (age >18 years) with suspected STEMI and who were eligible for PPCI were randomly allocated (1:1, stratified by centre with a permuted block method) to receive standard treatment (including a sham simulated remote ischaemic conditioning intervention at UK sites only) or remote ischaemic conditioning treatment (intermittent ischaemia and reperfusion applied to the arm through four cycles of 5-min inflation and 5-min deflation of an automated cuff device) before PPCI. Investigators responsible for data collection and outcome assessment were masked to treatment allocation. The primary combined endpoint was cardiac death or hospitalisation for heart failure at 12 months in the intention-to-treat population. This trial is registered with ClinicalTrials.gov (NCT02342522) and is completed. FINDINGS: Between Nov 6, 2013, and March 31, 2018, 5401 patients were randomly allocated to either the control group (n=2701) or the remote ischaemic conditioning group (n=2700). After exclusion of patients upon hospital arrival or loss to follow-up, 2569 patients in the control group and 2546 in the intervention group were included in the intention-to-treat analysis. At 12 months post-PPCI, the Kaplan-Meier-estimated frequencies of cardiac death or hospitalisation for heart failure (the primary endpoint) were 220 (8·6%) patients in the control group and 239 (9·4%) in the remote ischaemic conditioning group (hazard ratio 1·10 [95% CI 0·91-1·32], p=0·32 for intervention versus control). No important unexpected adverse events or side effects of remote ischaemic conditioning were observed. INTERPRETATION: Remote ischaemic conditioning does not improve clinical outcomes (cardiac death or hospitalisation for heart failure) at 12 months in patients with STEMI undergoing PPCI. FUNDING: British Heart Foundation, University College London Hospitals/University College London Biomedical Research Centre, Danish Innovation Foundation, Novo Nordisk Foundation, TrygFonden
Entreprise architecture implementation and management : a case study on interoperability
Meeting: Hawaii International Conference on System Sciences, 39th, 4-7 January, 2006, Hawaii, U
Enterprise architecture implementation and management : a case study on interoperability
The analysis shows that interoperability is not just a technical issue, and that economic and political factors are just as important when implementing enterprise architecture programs in government. The findings suggest that implementing enterprise calls for a broader definition of interoperability. Linking different public administrative services to provide quality and reliable e-government services requires an understanding of the complex organizational cooperation – and conflicts – in public agencies. The focus of this study is to explore why public agencies implement enterprise architecture programs and the interoperability challenges they are faced with
The strategic value of SOA:a comparative case study in the banking sector
Information and Communication Technology (ICT) has helped to drive increasingly intense global competition. In turn, this intensity increases the need for flexibility and rapid changeability in ICT to support strategies that depend on organisational agility. We report a comparative, cross-cultural case study of the implementation of Service-Oriented Architectures (SOA) at a Scandinavian bank and a Swiss bank. The strategic rewards in the adoption of SOA appear to go beyond marketplace issues of ICT capability acquisition, and unexpectedly arise in the creation of an extensible organisational ICT architecture. The extensibility of the ICT architecture that results from the adoption of SOA provides potential for greater organisational agility (and thereby competitiveness