Dermoid Cyst Arising from the Epiglottis

Dermoid cysts arising from the head and neck region are rare, slow-growing, and well-circumscribed neoplasms. Symptoms are non-specific and usually related to the size and the location of the lesion. A dermoid cyst of the epiglottis is extremely rare. To the best of our knowledge, only one case has been previously reported in the English literature. In this study, a case of a dermoid cyst arising from the epiglottis was presented as an extremely rare clinical condition. The characteristics, differential diagnosis, and treatment of the disease are summarized

Cervico-Thoracic Giant Lipoma in a Child

Lipomas are benign mesenchymal tumors that can be observed all over the body. In total, 25% of lipomas are observed in the head and neck region, and most of them are located in the posterior cervical triangle. Lipomas that are greater than 10 cm in width or more than 1000 g in weight are called giant tumors. Cervico– thoracic lipomas are extremely rare, and only four cases have been reported in the English literature. We report successful surgical excision of a giant lipoma, which started from middle-anterior cervical region covered the anterior cervical triangle, and extended to the mediastinum, without thoracotomy

Effect of high-fat diet on the various morphological parameters of the ovary

Increased food consumption rich in fat and carbohydrate and sedentary lifestyle have seriously increased the rates of obesity and obesity-associated diseases in developed countries. Female mice with diet-induced obesity exhibit infertility and thus can serve as a model for human polycystic ovary syndrome. The aim of the present study was to examine how ovary is affected by diet-induced obesity. The effects of high-fat diet (HFD) on ovary morphology in mice fed with HFD were investigated using unbiased stereological methods. The ovary of mice fed with HFD (n=8, C1090-60, Altromine) for 9 weeks, were compared with that of mice fed with standard chow diet (n=8, C1090-10, Altromine). Stereological parameters were obtained in diestrus cycle. The samples were processed through routine and standard paraffin embedding and were serially sectioned in 5-mu m thickness then, every 10th section was saved, stained with Crossman's triple stain for counting and measuring. In all sampled sections mean follicle numbers, diameters, total ovarian volume cortex to medulla ratio (Vv), ovum to cell ratio in secondary follicle were examined in all sampled sections. The present results showed that weight of ovarian and amount of intraperitoneal adipose tissue and the body weight markedly increased in obese mice when compared with control groups. Moreover, follicle numbers (except primordial follicles) and diameters were significantly increased in obese mice. Cortex to medulla ratio (Vv) and ovum to cell ratio in secondary follicle were also considerably different between experimental and the control groups. The present findings indicate that obesity adversely affects overall ovarian morphology.Eskişehir Osmangazi Üniversitesi (2014-586

Recent Advances in Health Biotechnology During Pandemic

The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which emerged in 2019, cut the epoch that will make profound fluctuates in the history of the world in social, economic, and scientific fields. Urgent needs in public health have brought with them innovative approaches, including diagnosis, prevention, and treatment. To exceed the coronavirus disease 2019 (COVID-19) pandemic, various scientific authorities in the world have procreated advances in real time polymerase chain reaction (RT-PCR) based diagnostic tests, rapid diagnostic kits, the development of vaccines for immunization, and the purposing pharmaceuticals for treatment. Diagnosis, treatment, and immunization approaches put for- ward by scientific communities are cross-fed from the accrued knowledge of multidisciplinary sciences in health biotechnology. So much so that the pandemic, urgently prioritized in the world, is not only viral infections but also has been the pulsion in the development of novel approaches in many fields such as diagnosis, treatment, translational medicine, virology, mi- crobiology, immunology, functional nano- and bio-materials, bioinformatics, molecular biol- ogy, genetics, tissue engineering, biomedical devices, and artificial intelligence technologies. In this review, the effects of the COVID-19 pandemic on the development of various scientific areas of health biotechnology are discussed

Combined service accounting in tourism establishments

YÖK Tez ID: 1906831990'lı yılların başlarından itibaren şirket birleşmeleri ve satın almalarla birlikte;farklı sektörlerde pek çok işletme büyüme eğilimine girmiştir. Turizm işletmelerindede, ayrı ayrı hizmet vermekte olan konaklama ve seyahat işletmelerinde birleşmelerolduğu ve bu işletmelerin tek çatı altında hizmet verdikleri görülmektedir. Buişletmelerin sayısı her geçen gün artmaktadır. Bu artış, kombine hizmet veren turizmişletmelerinde kullanılan muhasebe organizasyonlarının da incelenmesini gereklikılmıştır. Ancak ülkemizde turizm işletmelerinin muhasebe organizasyonlarıkonaklama ve seyahat işletmeleri olarak ayrı ayrı incelenmişken, kombine hizmetveren turizm işletmelerinin muhasebe organizasyonları araştırma konusu olmamıştır.Turizm işletmelerinde kombine hizmet verilmesinde, işletmenin iyi bir şekildeyönetilmesinin büyük önemi vardır. Bütün işletmelerde olduğu gibi bu işletmelerdede ileriye dönük planların yapılması ve uygulanması ancak iyi bir muhasebeorganizasyonunun varlığı ile mümkündür.Bu çalışma ile kombine hizmet veren turizm işletmelerinde doğru ve etkin birmuhasebe organizasyonunun sağlanabilmesi için kuramsal ve uygulamalı biraraştırma yapılarak turizm sektöründe faaliyet gösteren işletme yöneticilerine yolgösterebilmek ve uygulamada karşılaşılan kavram kargaşasına son verilmesiamaçlanmıştır. Tezin hazırlanabilmesi için, merkezi Ankara'da bulunan bir turizmişletmesi ile işletmenin İstanbul şubesi çalışma kapsamına alınmıştır. Merkez veşubede verilen her türlü hizmet ile bu hizmetlerin muhasebeleştirilmesi, merkez veşubenin yapmış oldukları gelir ve giderlerin kayıtları örneklerle incelenmiştir.As of the beginning of 1990s, together with company mergers and purchases;many business enterprises have took the tendency of growing. Also, it is seen in thetourism enterprises that mergers happen in the accommodation and travelenterprises that give service separately and that these enterprises give service underthe same roof. The number of these enterprises increases every day. This increasehas required the investigation of the accountancy organizations used in the tourismestablishments that give combined service. However, while the accountancyorganizations of the tourism establishments in our country have been investigatedseparately, the accountancy organizations of the tourism establishments that givecombine service have not been the subject of investigation.Managing the establishment in a very good manner in providing combinedservice in tourism establishments has a big importance. As is the case in allenterprises, making plans towards future and applying them is only possible also inthese establishments with the existence of a good accountancy organization.With this study, by making a theoretical and practical investigation, it hasbeen aimed to guide the managers of the establishments that do business in thetourism sector and end the concept confusion for being able to ensure a correct andeffective accountancy organization in the tourism establishments, which givecombined service. To be able to prepare the thesis, a tourism establishment and theIstanbul branch of the establishment have been taken into the scope of the study.Every kind of services and entering these services into accounts and the records ofthe incomes and expenses made by the main office and branch has been examinedin details with examples

Turizm işletmelerinde kombine hizmet muhasebesi

Tez (Yüksek Lisans) -- Kırıkkale Üniversitesi79006

A case with mutation in the TNFRSF1A gene

Tumor necrosis factor (TNF) receptor-associated periodic syndrome (TRAPS) is a rare autosomal dominant hereditary diseaseof the group of recurrent autoinflammatory syndromes. Theprognosis is generally good; the main risk is the developmentof amyloidosis. Corticosteroid therapy is usually administeredduring attacks. Severe cases require treatment with biologicalagents. In this study, DNA fragment analysis and next generation sequencing methods were applied to elucidate the patientwith recurrent fever and joint pain. A six-year-old girl with recurrent fever and joint pain was referred to a medical geneticsclinic for a etiologic study on the consideration of autoinflammatory disease. On physical examination, there was no featureexcept bilateral swelling in the knee. Echocardiography andknee magnetic resonance examination were unremarkable. Thesuperficial tissue ultrasonographic examination of the bilateralknee region was observed fluid accumulation 30 mm on the leftand 15mm on the right in the thickest site, at the suprapatellarlevel. Fluid was observed in the joint range. In the sample fromthe joint fluid, the white blood cell was 74000/m³. In the analysisof the peripheral blood, white blood cell count was 17.7x10³/µL,CRP: 31 mg/L, fibrinogen: 4.6g/L, sedimentation: 25 mm/h. The24-hour urine protein/creatinine was 0.27 mg/mg. FMF fragment analysis revealed no mutation and the diagnosis of FMFwas excluded. The next generation sequence analysis revealed alikely pathogenic, heterozygous c.362G&gt;A(R121Q; rs4149584) alteration of the TNFRSF1A gene (ENST00000162749). Then thesegregation analysis was planned. In this study, we pointed outthe TNFRSF1A mutation in periodic fever syndrome cases. Earlydiagnosis by genetic testing can prevent amyloidosis.</p

ÇEVİRİBİLİMİNDE THEO HERMANS BAĞLAMINDA DİZGE ODAKLI BİR YAKLAŞIM

Çeviride dizge odaklı yaklaşım denildiğinde akla ilk gelen isimlerden biri Çoğuldizge (Polysystem) Kuramı ile bilinen Itamar Even-Zohar’dır. Bununla birlikte, Belçikalı çeviribilimci Theo Hermans 1999’da yayımlanan Translation in Systems adlı eseriyle çeviride dizge odaklı yaklaşımları irdeleyip dizge kavramını açımlayarak Alman sosyolog Niklas Luhmann’ın dizge yaklaşımını çeviribilime uyarlamasıyla farklı bir bakış açısı getirmiştir. Bu makalede, Hermans’ın çeviride seksenli yıllardan itibaren tartışılan dizgesel yaklaşımları nasıl değerlendirdiğini ve özelde çeviri sosyolojisi alanında sınırlı bir ilgiyle karşılanan Luhmann’ın dizge kuramının çeviribilim alanında neden ve nasıl kullanılabileceğine yönelik görüşleri ele alınmıştır. Bu bağlamda, Hermans’ın Çoğuldizge Kuramı’nı hangi açılardan eleştirdiği ve söz konusu kuramdaki kavramsal yaklaşımları nasıl sorguladığı dile getirilmiştir. Çalışmada ayrıca, çeviribiliminde sosyolojiden aktarılan bazı kavramların çeviribilimine nasıl yansıdığı ve bunun çeviri biliminin sınırlarını nasıl genişlettiği irdelenmiştir. Dolayısıyla disiplinler arası ilişkilere açık bir alan olan çeviribilimin sosyolojiden nasıl etkilendiği Luhmann’ın kuramı çerçevesinde tartışılmıştır

Taze Betonun işlenebilirliğini Belirlemede Kalibrasyon işlemi ve

Taze betonların islenebilirlik ve reolojik özelliklerini belirlemek için henüz kabul edilmis bir yöntem ve cihaz bulunmamaktadır. Temel neden çok fazlı bir malzeme olan betonun bu özelliklerini ölçebilmek için gelistirilecek cihazlarda kalibrasyon islemlerinin yapılamamasıdır. Bu çalısmada taze betonun islenebilirligi, islenebilirligi etkileyen baslıca parametreler ve taze betonun islenebilirligini belirlemek için gelistirilmis olan Celsum iki Nokta işlenebilirlik Deney Cihazının (CTPT) kalibrasyonu, polidimetilsiloksan sıvısı kullanılarak incelenmistir. Ayrıca, CTPT cihazının polidimetisiloksan akıskanıyla kalibrasyonu için bir metodoloji gelistirilmistir. Bu metodoloji ve polidimetisiloksan sıvısı kullanılarak elde edilen parametreler, 0.27 ve 0.38 Su/Çimento oranlarında üretilen karısımların reolojik test parametrelerine (kayma esigi ve plastik viskozite) uygulanmıstır. Elde edilen deneysel çalısma ve hesaplamalara göre; önerilen polidimetisiloksan akıskanının taze beton islenebilirlik ölçüm cihazları için kalibrasyon sıvısı olarak kullanabilecegi sonucuna varılmıstır