An Invasive Species Assessment Protocol: Evaluating Non-Native Plants for Their Impact on Biodiversity, Version 1

NatureServe, in cooperation with The Nature Conservancy and the U.S. National Park Service, developed this Invasive Species Assessment Protocol as a tool for assessing, categorizing, and listing non-native invasive vascular plants according to their impact on native species and natural biodiversity in a large geographical area such as a nation, state, province, or ecological region. This protocol is designed to make the process of assessing and listing invasive plants objective and systematic, and to incorporate scientific documentation of the information used to determine each species’ rank. NatureServe’s methodology has previously included assessments of the conservation significance of native species; this protocol extends that scope to non-native species as well. The protocol is used to assess species (or infraspecific taxa, as appropriate) individually for a specified “region of interest” and to assign each species an Invasive Species Impact Rank (I-Rank) of High, Medium, Low, or Insignificant to categorize its negative impact on natural biodiversity within that region. The protocol includes 20 questions, each with four scaled responses (A-D, plus U = unknown). The 20 questions are grouped into four sections: Ecological Impact, Current Distribution and Abundance, Trend in Distribution and Abundance, and Management Difficulty. Each species is assessed by considering these questions, with the answers used to calculate a subrank for each of the four sections. An overall I-Rank is then calculated from the subranks. Text comments and citations to information sources should be provided as documentation for each answer selected, along with a concise text summary of the major considerations leading to the overall rank. While designed for use in a specified large, contiguous, biogeographically diverse region, the protocol can be adapted to specified noncontiguous regions (such as the 50 states of the United States), and may also be applied to assess the impact in the non-native range of a species that is also present elsewhere in a region as a native. NatureServe is now using this protocol to assess the biodiversity impact of the approximately 3,500 non-native vascular plant species established outside cultivation in the United States. The protocol is offered here in generalized form for others who might wish to use it to conduct similar assessments and create lists of invasive plants for other nations, states, provinces, ecological regions, or comparable areas

HOW IS THE VALUE OF REAL ESTATE AFFECTED BY THE DEPARTMENT OF DEFENSE BASE REALIGNMENT AND CLOSURE PROCESS?

This study examines the Department of Defense Base Realignment and Closure (BRAC) process as it relates to real estate prices in the communities surrounding the bases marked for closure and realignment. I examine the history of the BRAC process, detail the bases that have been marked for realignment and closure over the five “rounds” of the BRAC process to date (1988, 1991, 1993, 1995, 2005), and present a model that tests the hypothesis that BRAC closure announcements are correlated with the value of real estate in the local communities surrounding the bases marked for closure. I find that there is a strong and statistically significant correlation between the BRAC process, particularly the series of announcements that occur within the BRAC timeline, and the value of real estate in the local communities affected by the BRAC process. I also discuss policy implications of these findings for the Department of Defense, as well as future research areas and opportunities that have arisen as a result of this study

Health service experiences and preferences of frail home care clients and their family and friend caregivers during the COVID-19 pandemic

Objective: The COVID-19 pandemic has brought about a major upheaval in the lives of older adults and their family/friend caregivers, including those utilizing home care services. In this article, we focus on results from a qualitative component added to a pragmatic randomized controlled trial that focuses on the experiences of our study participants during COVID-19. A total of 29 participants responded to the COVID-19 related questions focused on their health services experiences and preferences from March-June 2020 including 10 home care clients and 19 family/friend caregivers in the provinces of Ontario and Nova Scotia, Canada. Results: Many participants were affected drastically by the elimination or reduction of access to services, highlighting the vulnerability of home care clients and their caregivers during COVID-19. This took an emotional toll on home care clients and increased the need for family/friend caregiver support. While many participants expressed reduced desire to utilize residential long-term care homes, some caregivers found that passive remote monitoring technology was particularly useful within the COVID-19 context. Our results provide important insights into the ways the older adults and their caregivers have been affected during the COVID-19 context and how to better support them in the future

Dorsal striatum does not mediate feedback-based, stimulus-response learning: An event-related fMRI study in patients with Parkinson\u27s disease tested on and off dopaminergic therapy

© 2018 Learning associations between stimuli and responses is essential to everyday life. Dorsal striatum (DS) has long been implicated in stimulus-response learning, though recent results challenge this contention. We have proposed that discrepant findings arise because stimulus-response learning methodology generally confounds learning and response selection processes. In 19 patients with Parkinson\u27s disease (PD) and 18 age-matched controls, we found that dopaminergic therapy decreased the efficiency of stimulus-response learning, with corresponding attenuation of ventral striatum (VS) activation. In contrast, exogenous dopamine improved response selection accuracy related to enhanced DS BOLD signal. Contrasts between PD patients and controls fully support these within-subject patterns. These double dissociations in terms of behaviour and neural activity related to VS and DS in PD and in response to dopaminergic therapy, strongly refute the view that DS mediates stimulus-response learning through feedback. Our findings integrate with a growing literature favouring a role for DS in decision making rather than learning, and unite two literature that have been evolving independently

Geographic and facility variation in initial use of non-tunneled catheters for incident maintenance hemodialysis patients

Abstract Background Non-tunneled (temporary) hemodialysis catheters (NTHCs) are the least-optimal initial vascular access for incident maintenance hemodialysis patients yet little is known about factors associated with NTHC use in this context. We sought to determine factors associated with NTHC use and examine regional and facility-level variation in NTHC use for incident maintenance hemodialysis patients. Methods We analyzed registry data collected between January 2001 and December 2010 from 61 dialysis facilities within 12 geographic regions in Canada. Multi-level models and intra-class correlation coefficients were used to evaluate variation in NTHC use as initial hemodialysis access across facilities and geographic regions. Facility and patient characteristics associated with the lowest and highest quartiles of NTHC use were compared. Results During the study period, 21,052 patients initiated maintenance hemodialysis using a central venous catheter (CVC). This included 10,183 patients (48.3 %) in whom the initial CVC was a NTHC, as opposed to a tunneled CVC. Crude variation in NTHC use across facilities ranged from 3.7 to 99.4 % and across geographic regions from 32.4 to 85.1 %. In an adjusted multi-level logistic regression model, the proportion of total variation in NTHC use explained by facility-level and regional variation was 40.0 % and 34.1 %, respectively. Similar results were observed for the subgroup of patients who received greater than 12 months of pre-dialysis nephrology care. Patient-level factors associated with increased NTHC use were male gender, history of angina, pulmonary edema, COPD, hypertension, increasing distance from dialysis facility, higher serum phosphate, lower serum albumin and later calendar year. Conclusions There is wide variation in NTHC use as initial vascular access for incident maintenance hemodialysis patients across facilities and geographic regions in Canada. Identifying modifiable factors that explain this variation could facilitate a reduction of NTHC use in favor of more optimal initial vascular access

Producción de anticuerpos monoclonales con aislamiento seleccionados del virus del mosaico dorado de frijol

Programa Cooperativo Regional de Frijol para Centroamérica, México y el Caribe (PROFRIJOL)Cooperación Suiza para el Desarrollo (COSUDE)Centro Internacional de Agricultura Tropical (CIAT)UCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias Agroalimentarias::Estación Experimental Agrícola Fabio Baudrit Moreno (EEAFBM

HDAC3 is a molecular brake of the metabolic switch supporting white adipose tissue browning.

White adipose tissue (WAT) can undergo a phenotypic switch, known as browning, in response to environmental stimuli such as cold. Post-translational modifications of histones have been shown to regulate cellular energy metabolism, but their role in white adipose tissue physiology remains incompletely understood. Here we show that histone deacetylase 3 (HDAC3) regulates WAT metabolism and function. Selective ablation of Hdac3 in fat switches the metabolic signature of WAT by activating a futile cycle of de novo fatty acid synthesis and β-oxidation that potentiates WAT oxidative capacity and ultimately supports browning. Specific ablation of Hdac3 in adipose tissue increases acetylation of enhancers in Pparg and Ucp1 genes, and of putative regulatory regions of the Ppara gene. Our results unveil HDAC3 as a regulator of WAT physiology, which acts as a molecular brake that inhibits fatty acid metabolism and WAT browning.Histone deacetylases, such as HDAC3, have been shown to alter cellular metabolism in various tissues. Here the authors show that HDAC3 regulates WAT metabolism by activating a futile cycle of fatty acid synthesis and oxidation, which supports WAT browning

Fitness Correlates Of Song Repertoire Size In Free-Living Song Sparrows (Melospiza Melodia)

Models of sexual selection propose that exaggerated secondary sexual ornaments indicate a male\u27s own fitness and the fitness of his offspring. These hypotheses have rarely been thoroughly tested in free-living individuals because overall fitness, as opposed to fitness components, is difficult to measure. We used 20 years of data from song sparrows ( Melospiza melodia) inhabiting Mandarte Island, British Columbia, Canada, to test whether a male\u27s song repertoire size, a secondary sexual trait, predicted overall measures of male or offspring fitness. Males with larger song repertoires contributed more independent and recruited offspring, and independent and recruited grandoffspring, to Mandarte\u27s population. This was because these males lived longer and reared a greater proportion of hatched chicks to independence from parental care, not because females mated to males with larger repertoires laid or hatched more eggs. Furthermore, independent offspring of males with larger repertoires were more likely to recruit and then to leave more grandoffspring than were offspring of males with small repertoires. Although we cannot distinguish whether observed fitness variation reflected genetic or environmental effects on males or their offspring, these data suggest that female song sparrows would gain immediate and intergenerational fitness benefits by pairing with males with large song repertoires

Imaging the dephasing of spin wave modes in a square thin film magnetic element

Copyright © 2004 The American Physical SocietyWe have used time-resolved scanning Kerr effect microscopy to study dephasing of spin wave modes in a square Ni81Fe19 element of 10 μm width and 150 nm thickness. When a static magnetic field H was applied parallel to an edge of the square, demagnetized regions appeared at the edges orthogonal to the field. When H was applied along a diagonal, a demagnetized region appeared along the opposite diagonal. Time-resolved images of the out-of-plane magnetization component showed stripes that lie perpendicular to H and indicate the presence of spin wave modes with wave vector parallel to the static magnetization. The transient Kerr rotation was measured at different positions along an axis parallel to H, and the power spectra revealed a number of different modes. Micromagnetic simulations reproduce both the observed images and the mode frequencies. This study allows us to understand an anisotropic damping observed at the center of the square element in terms of dephasing of the resonant mode spectrum