Circumnuclear Gas in Seyfert 1 Galaxies: Morphology, Kinematics, and Direct Measurement of Black Hole Masses

(Abridged) The two-dimensional distribution and kinematics of the molecular, ionized, and highly ionized gas in the nuclear regions of Seyfert 1 galaxies have been measured using high spatial resolution (~0''.09) near-infrared spectroscopy from NIRSPEC with adaptive optics on the Keck telescope. Molecular hydrogen, H2, is detected in all nine Seyfert 1 galaxies and, in the majority of galaxies, has a spatially resolved flux distribution. In contrast, the narrow component of the BrG emission has a distribution consistent with that of the K-band continuum. In general, the kinematics of H2 are consistent with thin disk rotation, with a velocity gradient of over 100 km/s measured across the central 0''.5 in three galaxies, and across the central 1''.5 in two galaxies. The kinematics of BrG are in agreement with the H2 rotation, except in all four cases the central 0''.5 is either blue- or redshifted by more than 75 km/s. The highly ionized gas, measured with the [Ca VIII] and [Si VII] coronal lines, is spatially and kinematically consistent with BrG in the central 0''.5. Dynamical models have been fitted to the two-dimensional H2 kinematics, taking into account the stellar mass distribution, the emission line flux distribution, and the point spread function. For NGC 3227 the modeling indicates a black hole mass of Mbh = 2.0{+1.0/-0.4} x 10^7 Msun, and for NGC 4151 Mbh = 3.0{+0.75/-2.2} x 10^7 Msun. In NGC 7469 the best fit model gives Mbh < 5.0 x 10^7 Msun. In all three galaxies, modeling suggests a near face-on disk inclination angle, which is consistent with the unification theory of active galaxies. The direct black hole mass estimates verify that masses determined from the technique of reverberation mapping are accurate to within a factor of three with no additional systematic errors.Comment: 43 pages, including 47 figures; Accepted for publication in ApJ. All 2-D maps (in high resolution) are available at http://www.astro.ucla.edu/~ehicks . Minor changes to the text and updated reverberation mapped black hole mass estimates; the conclusions are unchange

Engineering Virus Like Particles Towards Directing Immunologic Responses

This poster was presented during the 3rd Annual UT Tyler Faculty Research Poster Showcase.https://scholarworks.uttyler.edu/fac_posters/1008/thumbnail.jp

Codevelopment Between Key Personality Traits and Alcohol Use Disorder From Adolescence Through Young Adulthood

ObjectivePersonality traits related to negative emotionality and low constraint are strong correlates of alcohol use disorder (AUD), but few studies have evaluated the prospective interplay between these traits and AUD symptoms from adolescence to young adulthood.MethodThe Minnesota Twin Family Study (N = 2,769) was used to examine the developmental interplay between AUD symptoms and three personality measures of constraint, negative emotionality, and aggressive undercontrol from ages 17 to 29.ResultsResults from random‐intercept, cross‐lagged panel models showed that low constraint and aggressive undercontrol predicted subsequent rank‐order increases in AUD symptoms from ages 17 to 24. AUD symptoms did not predict rank‐order change in these traits from ages 17 to 24. There was support for both cross‐effects from ages 24 to 29. Biometric analysis of the twin data showed genetic influences accounted for most of the phenotypic correlations over time.ConclusionResults are consistent with the notion that personality traits related to low constraint and aggressive undercontrol are important vulnerability/predisposition factors for the development of early adult AUD. In later young adulthood, there is more evidence for the simultaneous codevelopment of personality and AUD. Implications are addressed with attention to personality‐based risk assessments and targeted AUD prevention approaches.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/142935/1/jopy12311.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/142935/2/jopy12311_am.pd

Leadership and decision-making practices in public versus private universities in Pakistan

The goal of this study is to examine differences in leadership and decision-making practices in public and private universities in Pakistan, with a focus on transformational leadership (TL) and participative decision-making (PDM). We conducted semi-structured interviews with 46 deans and heads of department from two public and two private universities in Pakistan. Our findings indicate that leadership and decision-making practices are different in public and private universities. While differences were observed in all six types of TL-behaviour, the following three approaches emerged to be crucial in both public and private universities: (1) articulating a vision, (2) fostering the acceptance of group goals, and (3) high-performance expectations. In terms of PDM, deans and heads of department in public and private universities adopt a collaborative approach. However, on a practical level this approach is limited to teacher- and student-related matters. Overall, our findings suggest that the leadership and decision-making practices in Pakistani public and private universities are transformational and participative in nature

The transcriptional repressor protein NsrR senses nitric oxide directly via a [2Fe-2S] cluster

The regulatory protein NsrR, a member of the Rrf2 family of transcription repressors, is specifically dedicated to sensing nitric oxide (NO) in a variety of pathogenic and non-pathogenic bacteria. It has been proposed that NO directly modulates NsrR activity by interacting with a predicted [Fe-S] cluster in the NsrR protein, but no experimental evidence has been published to support this hypothesis. Here we report the purification of NsrR from the obligate aerobe Streptomyces coelicolor. We demonstrate using UV-visible, near UV CD and EPR spectroscopy that the protein contains an NO-sensitive [2Fe-2S] cluster when purified from E. coli. Upon exposure of NsrR to NO, the cluster is nitrosylated, which results in the loss of DNA binding activity as detected by bandshift assays. Removal of the [2Fe-2S] cluster to generate apo-NsrR also resulted in loss of DNA binding activity. This is the first demonstration that NsrR contains an NO-sensitive [2Fe-2S] cluster that is required for DNA binding activity

Treatment of Travel Expenses by Golf Course Patrons: Sunk or Bundled Costs and the First and Third Laws of Demand

To attract golf patrons, sport managers must understand consumption patterns of the golfer. Importantly, the treatment of travel costs must be understood. According to the Alchian-Allen (1964) theorem, golfers treat travel costs as bundled costs (third law of economic demand) whereas classical consumer theory indicates that golfers treat travel costs as sunk costs (first law of economic demand). The purpose of this study was to determine if golf patrons treated travel costs as sunk costs or if they treated travel costs as a bundled cost. Data from a survey of course patrons in Ohio support the treatment of travel costs as bundled costs by golf course patrons, especially those classified as tourists. The strong, positive correlation found between distance traveled and the cost of greens fees enables managers to utilize geographic segmentation in choosing to whom to market their course based upon their product’s price compared to area competitors