1,730 research outputs found

    Technical Bulletins: Conducting A Special Census

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    This Technical Bulletin provides information about the two types of special censuses (census of annexed territory and citywide census) and their costs

    Cladding mode coupling in highly localized fiber Bragg gratings: modal properties and transmission spectra

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    The spectral characteristics of a fiber Bragg grating (FBG) with a transversely inhomogeneous refractive index profile, differs con- siderably from that of a transversely uniform one. Transmission spectra of inhomogeneous and asymmetric FBGs that have been inscribed with focused ultrashort pulses with the so-called point-by-point technique are investigated. The cladding mode resonances of such FBGs can span a full octave in the spectrum and are very pronounced (deeper than 20dB). Using a coupled-mode approach, we compute the strength of resonant coupling and find that coupling into cladding modes of higher azimuthal order is very sensitive to the position of the modification in the core. Exploiting these properties allows precise control of such reflections and may lead to many new sensing applications.Comment: Submission to OE, 16 pages, 6 figure

    Influence of MWCNT/surfactant dispersions on the mechanical properties of Portland cement pastes

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    This work studies the reinforcing effect of Multi Walled Carbon Nanotubes (MWCNT) on cement pastes. A 0.35% solid concentration of MWCNT in powder was dispersed in deionized water with sodium dodecyl sulfate (cationic surfactant), cetylpyridinium chloride (anionic surfactant) and triton X-100 (amphoteric surfactant) using an ultrasonic tip processor. Three concentrations of each surfactant (1mM, 10mM and 100mM) were tested, and all samples were sonicated until an adequate dispersion degree was obtained. Cement pastes with additions of carbon nanotubes of 0.15% by mass of cement were produced in two steps; first the dispersions of MWCNT were combined with the mixing water using an ultrasonic tip processor to guarantee homogeneity, and then cement was added and mixed until a homogeneous paste was obtained. Direct tensile strength, apparent density and open porosity of the pastes were measured after 7 days of curing. It was found that the MWCNT/surfactants dispersions decrease the mechanical properties of the cement based matrix due to an increased porosity caused by the presence of surfactants. © Published under licence by IOP Publishing Ltd

    Tandem high dose therapy with hematopoietic progenitor cell rescue in children with high-risk solid tumors

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    Bivariate stochastic modeling of functional response with natural mortality

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    A correction due to Abbott (1925) is the standard method of dealing with control mortality in insect bioassay to estimate the mortality of an insect conditional on control mortality not having occurred. In this article a bivariate stochastic process for overall mortality is developed in which natural mortality and predation are jointly modeled to take account of the competing-risks associated with prey loss. The total mortality estimate from this model is essentially identical with that from more classical modeling. However, when predation loss is estimated in the absence of control mortality the results are somewhat different, with the estimate from the bivariate model being lower than that from using Abbott’s formula in conjunction with the classical model. It is argued that overdispersion in observed mortality data corresponds to correlated outcomes (death or survival) for the prey initially present, while Abbott’s correction relies implicitly on independence

    Retropharyngeal Abscess and Pott’s Disease Due to Tuberculosis: A Case Report

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    Introduction: Extrapulmonary mycobacterial infection can lead to vertebral spondylitis and osteomyelitis (Pott’s disease). Retropharyngeal abscess with concurrent spinal osteomyelitis is a rare presentation of tuberculosis in the US. Chart review on a patient was completed, and the relevant published literature was reviewed. Case Presentation: A previously healthy 34-year-old male originally from Sudan presented to an outside hospital with a 2-month history of neck pain, sore throat, odynophagia, fevers, and chills. MRI showed a retropharyngeal abscess and suspected cervical spine osteomyelitis. Acid-fast bacillus (AFB) smear was positive from a neck drain specimen, but sputum was negative. Chest imaging did not show findings consistent with pulmonary tuberculosis. He was treated with rifampin, isoniazid, pyrazinamide, and ethambutol (RIPE) along with moxifloxacin and linezolid due to concern for possible multidrug resistant tuberculosis and transferred to our center for further care. Culture isolated Mycobacterium tuberculosis. CT neck showed vertebral tuberculous osteomyelitis (Pott’s disease) of C1-C3 with a multiloculated retropharyngeal and prevertebral abscess (Figure 1). The patient was taken to the OR for posterior spinal fusion from occiput to C4 and transoral incision and drainage of the abscess. The post-operative course was uneventful, and moxifloxacin and linezolid were discontinued when Xpert MTB/RIF test revealed rifampin susceptibility. At follow-up the patient’s symptoms had resolved. Patient consent was obtained to utilize this case for educational purposes. Conclusions: This report presents the multidisciplinary treatment of this patient requiring infection control measures and antibiotic therapy by infectious disease, posterior spine fusion by orthopedic surgery, and retropharyngeal abscess drainage by otolaryngology

    Constructing a definition: Adolescent wellbeing from the perspective of the child and expert

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    Background: Adolescent’s wellbeing is gaining increasing attention, with it being part of the United Nations sustainable goals (United Nations, 2019 [online]). The question regarding what adolescent’s wellbeing is, however, has received no rigorous answer (Alexandrova, 2017), even though it is regarded as a fundamental measure of learning and growing as a human being (Stevens & Jarden, 2019). Understanding what wellbeing means to adolescents is vital and an under-researched area (Dunlop-Bennett et al., 2019) which has implications for the development and validation of tools to measure their wellbeing. Construct definition development literature highlights that experts, in addition to the relevant population, need to be consulted about the subject area to form a representative and valid definition (Podsakoff et al., 2016). Method: Two groups were invited to interview with the aim to understand their conceptualisations of wellbeing. Group 1consisted of both expert practitioners and researchers from different disciplines in the field of wellbeing (n = 8) and Group 2were young people aged 11-16 (n = 41). Conclusion: Any definition needs to be reflective of the multi-faceted nature of wellbeing. Findings revealed three themes: holism, positive feelings, and external influences. Based on these findings a definition of wellbeing was formed. These conclusions should be used to underpin research with adolescents and the development of a measure of young people’s wellbeing

    Item Development and Face Validity of the Rheumatoid Arthritis Patient Priorities in Pharmacological Interventions Outcome Measures

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    © 2015, Springer International Publishing Switzerland. Background: The assessment of rheumatoid arthritis (RA) is dominated by core sets and indices that have been developed by RA professionals. Previous research developed a set of eight priority treatment outcomes generated by patients to complement the professionally developed core sets for RA. Objective: This study aimed to facilitate quantitative measurement of these outcomes. Methods: Two consultation meetings with patient research partners diagnosed with RA (n=18) were held to identify face validity in existing instruments (Phase 1) at the Bristol Royal Infirmary. Where validated measures did not exist, new numerical rating scales (NRS) were constructed and discussed at two focus groups with patients diagnosed with RA (n=8) at the Bristol Royal Infirmary and the Royal National Hospital for Rheumatic Diseases (Phase 2). Feedback on the stem question, time frame, anchors and layout was recorded and transcribed verbatim. Results: Of the eight priorities, existing NRS for pain, activities of daily living and fatigue were voted as acceptable (Phase 1), but new NRS were required for five priorities. The partners strongly recommended that the three separate domains of severity, effect and ability to cope in each measurement area be assessed, as in the existing validated fatigue NRS. Focus group participants (Phase 2) made significant contributions to the phrasing of questions, for example how to ensure ‘mobility’ could be uniformly understood and how changes in valued activities be judged appropriately. Conclusion: Through extensive patient feedback, 24 NRS were constructed based on priorities identified by patients and encompassing domains where existing questionnaires contain many more items and do not address three important concepts endorsed by patients: severity, effect and coping. The Rheumatoid Arthritis Patient Priorities in Pharmacological Interventions patient-reported outcome measures are now ready for the evaluation of comprehension, construct validity and sensitivity through an observational study
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