The Murchison Widefield Array: The Square Kilometre Array Precursor at Low Radio Frequencies

The Murchison Widefield Array (MWA) is one of three Square Kilometre Array Precursor telescopes and is located at the Murchison Radio-astronomy Observatory in the Murchison Shire of the mid-west of Western Australia, a location chosen for its extremely low levels of radio frequency interference. The MWA operates at low radio frequencies, 80–300 MHz, with a processed bandwidth of 30.72 MHz for both linear polarisations, and consists of 128 aperture arrays (known as tiles) distributed over a ~3-km diameter area. Novel hybrid hardware/software correlation and a real-time imaging and calibration systems comprise the MWA signal processing backend. In this paper, the as-built MWA is described both at a system and sub-system level, the expected performance of the array is presented, and the science goals of the instrument are summarised

Finishing the euchromatic sequence of the human genome

The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead

Men, masculinities and heart disease: a systematic review of the qualitative literature

The aim of this study was to synthesize qualitative data on men's experiences of coronary heart disease (CHD). The authors searched for qualitative papers published before January 2007 in MEDLINE, EMBASE, British Nursing Index, CINAHL, PsychINFO and Web of Knowledge and used thematic analysis to synthesize findings. They found 136 studies that collected data on men's experiences of CHD. Only 27 studies took a gendered approach and only two aimed to investigate men's gendered experiences of CHD. Many men drew on discourses associated with hegemonic masculinity (e.g. demonstrating stoicism through delaying seeking professional help) when talking about the implications of the disease for their identity, relationships and paid work. However, some accounts challenged this dominant discourse. The authors argue that a more nuanced understanding of hegemonic masculinity should take account of the production of gendered narratives in the interview context, given that men 'do' gender when they give the impression of 'not doing' health

Anxiety as a mediator between perfectionism and eating disorders.

There is a strong link between perfectionism and eating disorders, yet little research to date has examined mediators of this relationship. The aim of this study was to investigate the mediating effect of anxiety on the relationship between perfectionism and eating pathology in a clinical sample (N = 370, M age = 25.04, 99 % female) of treatment-seeking eating disorder patients (bulimia nervosa—41 %; eating disorder not otherwise specified—41 %; anorexia nervosa—18 %). Results from structural equation modeling indicated that anxiety partially mediated the relationship between self-oriented perfectionism and eating disorder psychopathology. The findings suggest the role of anxiety and perfectionism within cognitive-behavioral models of eating pathology, and have implications for the treatment of eating disorders