Experimental investigations on the Chlorine-induced corrosion of HVOF thermal sprayed Stellite-6 and NiAl coatings with fluidised bed biomass/anthracite combustion systems

Stellite-6 (Co-based) and NiAl coatings (Ni-based) were deposited via HVOF spraying onto 304 stainless steels and tested in a 20 kWth biomass fired bubbling fluidised bed (BFB) combustor for 20 hours and an industrial scale anthracite fired CFB boiler for 1630 hours. Stellite-6 showed excellent corrosion resistance in both fluidised bed combustion systems because of the formation of outermost Cr2O3 layer and the spinel CoCr2O4 beneath, whereas NiAl coatings' anti-corrosion performance was significantly depleted due to the chlorine attack, and the resultant formation of Al2O3 layer at the coating/substrate interface finally led to coating spallation in both systems

Exo-circRNAs: a new paradigm for anticancer therapy

Abstract CircRNAs, as new members of long noncoding RNAs, have been the focus of recent investigation. CircRNAs feature a closed continuous loop structure without 5′-3′ polarity or a poly A tail. Many studies have reported the potential application of circRNAs in the clinic as new biomarkers and therapeutic targets in different diseases, especially for cancer. Additionally, the exosomes are important vehicles in cell-to-cell communication. And exo-circRNAs are circRNAs in exosomes which can be detected to provide additional evidence for conventional diagnostic methods and can be applied to suppress the malignant progress in cancer. In this review, we describe the biogenesis, characteristics, and functions of circRNAs and exosomes. Specifically, we present a comprehensive update of the promising role of exo-circRNAs in anticancer therapy